Loss of circadian rhythm in luminal acidity of canine stomach by implantation of a gastric fistula.

abstract：BACKGROUND:Leptin is a pleiotropic hormone that is involved in the regulation of food intake and body weight. Recent findings demonstrated that leptin receptors are present in the pancreas but the involvement of leptin in pancreatitis remains unknown. The aim of the present study was: (1) to assess plasma leptin levels...

journal_title：Digestion

authors： Konturek PC,Jaworek J,Maniatoglou A,Bonior J,Meixner H,Konturek SJ,Hahn EG

更新日期：2002-01-01 00:00:00

abstract：:Differential absorption of D-xylose and 3-O-methyl-D-glucose, and unmediated intestinal permeation of lactulose and L-rhamnose has been investigated in 14 patients with diarrhoea following tropical exposure and in 16 healthy control subjects. Five had malabsorption of fat, D-xylose and B12 ('tropical malabsorption' (T...

journal_title：Digestion

authors： Cook GC,Menzies IS

更新日期：1986-01-01 00:00:00

abstract：:This study examined the morphological and functional adaptations occurring in the jejunum of adult rats fed totally by parenteral nutrition during a 4-day period. Comparison was made with sham-operated animals receiving orally a similar isocaloric diet. The intravenously fed rats exhibited a 20% shortening of the vill...

journal_title：Digestion

authors： Raul F,Galluser M,Doffoel M

更新日期：1984-01-01 00:00:00

abstract：:Studies with short-term administration of omeprazole in patients with erosive or ulcerative reflux oesophagitis have demonstrated that strong inhibition of gastric acid secretion will become the therapy of choice for these patients. However, because reflux oesophagitis relapses rapidly when short-term treatment is dis...

journal_title：Digestion

authors： Jansen JB,Lamers CB

更新日期：1989-01-01 00:00:00

abstract：:The case of a 52-year-old male with chronic active type B hepatitis in whom severe exacerbation of liver disease was associated with interferon alpha treatment is described. It seems that patients with very active forms of chronic hepatitis B may experience severe and symptomatic exacerbation of liver disease during i...

journal_title：Digestion

authors： Laskus T,Radkowski M,Slusarczyk J,Cianciara J

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Capsule endoscopy (CE) has been recognised as an important investigational tool in the diagnosis of gastrointestinal disease. Studies have shown that CE can identify lesions in the upper gastrointestinal tract as well as in the small intestine. However, contrary to conventional oesophagogastroscopy ...

journal_title：Digestion

authors： Peter S,Heuss LT,Beglinger C,Degen L

更新日期：2005-01-01 00:00:00

abstract：:Groups of Sprague-Dawley rats were given placebo or prostaglandin E2 (PGE2) at 25 or 5,000 micrograms/kg or 15,R,15-methyl-PGE2 (MePGE2) at 5 or 50 micrograms/kg, twice daily, orally, for 1 month. Histological sections from the proximal duodenum were processed for immunohistochemistry and the volume density of immunor...

journal_title：Digestion

authors： Kapraali M,Söderman C,Marín L,Johansson O,Theodorsson E,Uribe A

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Upper gastrointestinal bleeding (UGB) is an important precipitating factor for the development of hepatic encephalopathy (HE) in cirrhotic patients. The aim of this study was to evaluate the efficacy of lactulose in a controlled randomized trial for prophylaxis of HE after UGB. PATIENTS AND METHODS...

journal_title：Digestion

authors： Wen J,Liu Q,Song J,Tong M,Peng L,Liang H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Many studies have recently been published on acute pancreatitis; however, few large-sample studies have been focused on the risk factors for deaths in severe acute pancreatitis. To address this issue, the present study was intended to assess etiology, severity, and mortality of acute pancreatitis in the...

journal_title：Digestion

authors： Bai Y,Jia L,Wang B,Yang B,Wang L,Shi X,Zhang W,Liu Y,Zou D,Li Z

更新日期：2007-01-01 00:00:00

abstract：:Crohn's disease and ulcerative colitis represent distinct phenotypic forms of inflammatory bowel disease and continue to be a common cause of morbidity. The corticosteroids and the immunomodulatory drugs, which are the basis of treatment for the inflammatory bowel diseases, do not assure always satisfactory outcomes. ...

journal_title：Digestion

authors： Ioannidis O,Varnalidis I,Paraskevas G,Botsios D

更新日期：2011-01-01 00:00:00

abstract：:We demonstrate that, in patients taking non-steroidal anti-inflammatory drugs (NSAIDs), there is inhibition of the proliferation of mucosal cells that normally leads to healing of duodenal ulcers. A microdissection technique was used to quantitate mitosis in duodenal crypts at the ulcer edge, giving a regeneration ind...

journal_title：Digestion

authors： Levi S,Goodlad RA,Lee CY,Stamp G,Walport MJ,Wright NA,Hodgson HJ

更新日期：1992-01-01 00:00:00

abstract：:Daily faecal calcium and magnesium outputs were inversely related to food-stimulated colonic intraluminal pressure in diverticular disease subjects. There was no relationship to sodium potassium and bile acid concentrations, nor to intestinal transit. ...

journal_title：Digestion

authors： Eastwood MA,Smith AN,Mitchell WD,Pritchard JL

更新日期：1980-01-01 00:00:00

abstract：:A 3 years evolution with amyloid involvement, primarily of the liver, in a patient is described. This led to intrahepatic cholestasis and to portal hypertension with esophageal varices. ...

journal_title：Digestion

authors： Melkebeke P,Vandepitte J,Hannon R,Fevery J

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND/AIMS:We evaluated the diagnostic variability and reproducibility of endoscopic signs in two populations with a different pretest likelihood of celiac disease (CD). METHODS:We recruited 289 CD patients (both adults and children) in a multicenter prospective study. Group 1 (high risk) included 111 patients re...

journal_title：Digestion

authors： Pellegrino S,Furfaro F,Tortora A,Naso P,D'Agate C,Spina M,Belluardo N,Bertone A,Passanisi G,Malandrino S,Familiari L,Villanacci V,Puzzo L,Tuccari G,Sciacca A,Vieni G,Costa S,Currò G,Magazzù G,Sferlazzas C,Bassotti

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) has become the standard endoscopic treatment for early gastric cancer without lymph node metastasis. At present, undifferentiated type intramucosal cancers without ulcer findings <20 mm in size are often chosen as endoscopic treatment lesions for expanded indication. Th...

journal_title：Digestion

authors： Kamada K,Tomatsuri N,Yoshida N

更新日期：2012-01-01 00:00:00

abstract：:Retractile mesenteritis is an extremely rare disease characterised by a non-specific inflammatory and fibrotic process of the mesenteric adipose tissue, which is usually accompanied by pain and a variety of other abdominal symptoms. We describe here the case of a patient with retractile mesenteritis presenting with pr...

journal_title：Digestion

authors： Papadaki HA,Kouroumalis EA,Stefanaki K,Roussomoustakaki M,Daskalogiannaki ME,Reppa D,Eliopoulos GD

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Impaired intestinal epithelial barrier function is a hallmark of a variety of pathological conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). IBD patients with IBS-like symptoms show higher interleukin-13 (IL-13) serum levels and poor psychological well-being. Supplemen...

journal_title：Digestion

authors： Li M,Oshima T,Ito C,Yamada M,Tomita T,Fukui H,Miwa H

更新日期：2019-09-18 00:00:00

abstract：:Life events and daily stress were assessed in patients with duodenal ulcer, active or in remission, and in matched disease and normal controls. The mean positive life event scores were significantly lower in duodenal ulcer patients than in disease and healthy controls, and lower in patients with active ulcer than in t...

journal_title：Digestion

authors： Hui WM,Shiu LP,Lok AS,Lam SK

更新日期：1992-01-01 00:00:00

abstract：:Intestinal absorption after extensive small bowel resections, for diseases other than Crohn's disease, was studied in 17 patients. When the ileocecal valve and the right colon were preserved, malabsorption was transient and moderate and had no prejudicial nutritional effect (fecal fat: 8.8 +/- 1.8 g/24 h in resections...

journal_title：Digestion

authors： Cosnes J,Gendre JP,Le Quintrec Y

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:In order to perform small bowel manometry studies in man, the probes have to be guided through the upper gastrointestinal tract. This is usually controlled by fluoroscopy, but a method that allows to place the tubes without X-rays is obviously desirable. METHODS:A new method that controls tube placing by so...

journal_title：Digestion

authors： V Schönfeld J

更新日期：2008-01-01 00:00:00

abstract：:Rats were given 59Fe (28 micrograms) together with doses of 0, 2 and 200 micrograms of uroporphyrin III in paired observations. Absorption of 59Fe was determined by comparing whole body counts of the rats 30 min and 7 days after dosing. Prior treatment with 200 micrograms of uroporphyrin twice daily for 3 days was ass...

journal_title：Digestion

authors： Weaver GA,Franck CA,Harris MD,Peters T Jr

更新日期：1991-01-01 00:00:00

abstract：:The effects of certain chemical additives on, and the molecular characteristics of, the intestinal proteases of the suckling rat have been investigated. The catheptic activity of the intestinal wall was thiol dependent, whereas the luminal protease was markedly inhibited by trypsin inhibitor. There was no significant ...

journal_title：Digestion

authors： Jones RE

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND/AIMS:As opposed to regular C-reactive protein (CRP) assays, the introduction of high-sensitivity ones has enabled us to detect low grade inflammation in patients with inflammatory bowel disease (IBD). We addressed the subject of the degree of correlation between the concentration of high-sensitivity CRP (hs-...

journal_title：Digestion

authors： Zilberman L,Maharshak N,Arbel Y,Rogowski O,Rozenblat M,Shapira I,Berliner S,Arber N,Dotan I

更新日期：2006-01-01 00:00:00

abstract：:Sedation and analgesia is the standard of care during diagnostic and therapeutic endoscopic gastrointestinal procedures in most areas of the world. Unsedated endoscopy is feasible in selected patients, but requires commitment on the part of both the patient and the provider. The American Society of Anesthesiologists h...

journal_title：Digestion

authors： Paspatis GA,Tribonias G,Paraskeva K

更新日期：2010-01-01 00:00:00

abstract：:Activation of enzyme phospholipase A2 (EC 3.1.1.4), the major liberator of arachidonic acid, has been proposed as a component in the pathogenesis of inflammatory bowel disease. To test the hypothesis that phospholipase A2 activity is increased in ulcerative colitis, enzyme activity was investigated in colonic biopsies...

journal_title：Digestion

authors： Almer S,Franzén L,Olaison G,Smedh K,Ström M

更新日期：1991-01-01 00:00:00

abstract：:Since biguanides are known to inhibit hexose and amino acid absorption in vivo and in vitro as well as vitamin B12 absorption the effect of phenethylbiguanide on taurocholate (TC) and water absorption was measured in rat ileum in vivo. Phenethylbiguanide exhibited a time-dependent inhibitory effect on TC- and water ab...

journal_title：Digestion

authors： Caspary WF,Lücke H

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND/AIMS:Evaluation of the response of gastroesophageal reflux disease (GERD) symptoms to treatment would be facilitated by a brief, valid, reliable and responsive, self-assessed GERD-sensitive scale. We therefore developed the Reflux Questionnaire (ReQuest). This publication describes the psychometric evaluatio...

journal_title：Digestion

authors： Mönnikes H,Bardhan KD,Stanghellini V,Berghöfer P,Bethke TD,Armstrong D

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adenosine deaminase (ADA)-deficient disease, a severe combined immunodeficiency, is most commonly associated with gastrointestinal disorders such as ulcer. The present study investigated the role of ADA in the pathogenesis of gastric ulcer. METHODS:ADA activity was measured in a variety of organs and t...

journal_title：Digestion

authors： Yaguchi T,Saito M,Yasuda Y,Nishizaki T

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:The benefits of colonoscopy in reducing colorectal cancer (CRC) risk for patients over 75 years are controversial. We aimed to determine whether colonoscopy use is associated with a decreased risk of CRC in patients 76-85 years old in the United States (US). PATIENTS AND METHODS:All patients in the Med...

journal_title：Digestion

authors： Wang YR,Cangemi JR,Loftus EV Jr,Picco MF

更新日期：2016-01-01 00:00:00

abstract：:High-fidelity simulation uses simulators that combine all of the physiological and pharmacological responses of a human in a manikin. These simulators change and respond to the users and trainees. Using simulators for teaching sedation in the field of gastroenterology unifies all the advantages of manikins. To underst...

journal_title：Digestion

authors： Hofmann N,Datz C,Schöchl H

更新日期：2010-01-01 00:00:00