How does the esophageal epithelium maintain its integrity?

abstract：BACKGROUND/AIMS:Autoimmune gastritis (AIG) may predispose to gastric carcinoid tumors or adenocarcinomas and may also cause unexplained iron and/or vitamin B(12) deficiency. The aims of this study were to explore clinical manifestations, endoscopic findings and laboratory features of patients with AIG. METHODS:109 pat...

journal_title：Digestion

authors： Soykan I,Yakut M,Keskin O,Bektaş M

更新日期：2012-01-01 00:00:00

abstract：:The effects of certain chemical additives on, and the molecular characteristics of, the intestinal proteases of the suckling rat have been investigated. The catheptic activity of the intestinal wall was thiol dependent, whereas the luminal protease was markedly inhibited by trypsin inhibitor. There was no significant ...

journal_title：Digestion

authors： Jones RE

更新日期：1980-01-01 00:00:00

abstract：:Omeprazole is a very potent and long-acting inhibitor of gastric acid secretion. These characteristics make the drug very suitable for the management of gastric acid hypersecretion and symptom relief in patients with the Zollinger-Ellison syndrome, and in the treatment of patients with ulcers resistant to histamine H2...

journal_title：Digestion

authors： Meijer JL,Jansen JB,Lamers CB

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Symptoms caused by chronic pancreatitis (CP) are common but often elusive hampering therapeutic decisions. Though correlations of morphologic findings in imaging and clinical appearance remain vague. We aimed in investigating whether a distinct combination of clinical parameters can better define the extent ...

journal_title：Digestion

authors： Perkhofer L,Besold T,Schmidberger J,Seufferlein T,Hann A,Müller M,Kleger A

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) of early esophageal cancer (EC) is becoming more widespread. Post-ESD coagulation syndrome (CS) has been proposed as temporary inflammatory signs that occur during the post-ESD period caused by transmural thermal injury by electrocoagulation. This retrospective study ai...

journal_title：Digestion

authors： Sakai M,Sohda M,Saito H,Ubukata Y,Nakazawa N,Kuriyama K,Hara K,Sano A,Ogata K,Yokobori T,Kuwano H,Shirabe K,Saeki H

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND/AIMS:Combined pH-metry/multichannel intraluminal impedance (pH/MII) measurement enables to measure gastroesophageal reflux despite ongoing proton pump inhibitor therapy. The aim of our study was to evaluate the influence of an escalating medical anti-reflux therapy with 40 mg esomeprazole, 80 mg esomeprazole...

journal_title：Digestion

authors： Bajbouj M,Becker V,Phillip V,Wilhelm D,Schmid RM,Meining A

更新日期：2009-01-01 00:00:00

abstract：:Discussion over the role of enzyme therapy in patients with acute pancreatitis is based upon theoretical considerations rather than hard data. In this respect, it differs little from most other treatments used in the management of acute pancreatitis, although, in the case of enzyme treatment, the lack of data results ...

journal_title：Digestion

authors： McMahon MJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to examine the relationship between narrow-band imaging (NBI) magnifying observation using the surface pattern as the main evaluation criterion and pit pattern diagnosis on the basis of magnifying observation using a dye in relation to the characteristics of colorectal tumors ac...

journal_title：Digestion

authors： Hayashi N,Tanaka S,Kanao H,Oka S,Yoshida S,Chayama K

更新日期：2013-01-01 00:00:00

abstract：:The prognosis for the acute healing of patients with persistent, erosive or ulcerative reflux oesophagitis depends upon the choice of drug treatment as well as the severity of the initial oesophagitis. The results of this study show that omeprazole, 40 mg once daily (n = 51), is more effective than ranitidine, 300 mg ...

journal_title：Digestion

authors： Lundell L

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study investigated the safety of endoscopic variceal ligation (EVL) under conscious sedation with midazolam and sequential flumazenil after procedure in these patients. METHODS:A total of 279 patients who underwent secondary prophylactic EVL at our institution between April 2012 and June 2014, wer...

journal_title：Digestion

authors： Kim SI,Jin YJ,Lee SH,Lee JW,Lee DH,Lee D

更新日期：2015-01-01 00:00:00

abstract：:The pancreatic exocrine secretory response to increasing doses of exogenous caerulein with and without a background infusion of secretin was studied in 5 healthy volunteers. Caerulein over a full range of doses (2.3-37 pmol/kg/h) produced increasing enzyme secretion up to 18.5 pmol/kg/h, whereas 37 pmol/kg/h was clear...

journal_title：Digestion

authors： Beglinger C,Köhler E,Stalder GA,Jansen J,Gyr K

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Different food items are made responsible for irritable bowel syndrome (IBS) symptoms, but the physiopathology of IBS remains unclear. AIMS:During a meeting in Nice, France, experts of the European Working Team of the IBiS Club discussed selected data regarding the relationships between alimentation, food i...

journal_title：Digestion

authors： Dapoigny M,Stockbrügger RW,Azpiroz F,Collins S,Coremans G,Müller-Lissner S,Oberndorff A,Pace F,Smout A,Vatn M,Whorwell P

更新日期：2003-01-01 00:00:00

abstract：:2 cases of pancreatic disease in patients with malabsorption following small bowel radiation injury are reported. It is suggested that the pancreatic disease present in these patients occurred as a result of previous radiotherapy. ...

journal_title：Digestion

authors： Mitchell CJ,Simpson FG,Davison AM,Losowsky MS

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) is a chronic immune-mediated disorder of the gastrointestinal tract. The pathophysiological understanding of this disease is limited and no curative therapy is available so far. Therefore, most patients require long-lasting or even life-long immunosuppressive therapies for the suppressio...

journal_title：Digestion

authors： Vetter M,Neurath MF

更新日期：2018-01-01 00:00:00

abstract：:Combining the narrow-band imaging (NBI) system and magnifying endoscopy allows simple and clear visualization of microscopic structures of the superficial mucosa and its capillary patterns, which may be useful for precise endoscopic diagnosis in the gastrointestinal tract, being more closely to histopathological diagn...

journal_title：Digestion

authors： Okubo M,Tahara T,Shibata T,Nakamura M,Kamiya Y,Yoshioka D,Maeda Y,Yonemura J,Ishizuka T,Arisawa T,Hirata I

更新日期：2011-01-01 00:00:00

abstract：:The influences of secretagogues and of elevated serum calcium concentrations on the calcium secretion from the cat pancreas have been studied in vivo. During a high and constant fluid secretion rate evoked by a background infusion of secretin, additional infusions of both cholecystokinin-pancreozymin and urecholine le...

journal_title：Digestion

authors： Layer P,Hotz J,Goebell H

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The exact etiology of irritable bowel syndrome (IBS) remains unclear. Curative treatment is not available and current treatment modalities are mainly directed against the predominant symptoms. There are a few studies reporting the beneficial effects of transcutaneous electrical stimulation in patients with c...

journal_title：Digestion

authors： Coban Ş,Akbal E,Köklü S,Köklü G,Ulaşlı MA,Erkeç S,Aktaş B,Yüksel O,Koçak E,Erdem HR

更新日期：2012-01-01 00:00:00

abstract：:The diagnostic value of serum ferritin levels was evaluated in 19 patients with biopsy-proven primary hepatocellular carcinoma (PHC) and 26 patients with chronic liver disease (CLD). Serum ferritin levels were significantly elevated in PHC, as compared with CLD and controls (p less than 0.0005). Similarly, serum ferri...

journal_title：Digestion

authors： Giannoulis E,Arvanitakis C,Nikopoulos A,Doutsos I,Tourkantonis A

更新日期：1984-01-01 00:00:00

abstract：:Biliopancreatic bypass (BPB), a bariatric surgical procedure, leads to a malnutrition-induced general visceral atrophy except for the pancreas. This work investigates the implication of cholecystokinin (CCK) in the exocrine pancreatic adaptive process using a plasma CCK assay and the CCK receptor antagonist CR 1409. N...

journal_title：Digestion

authors： Evrard S,Hoeltzel A,Aprahamian M,Bernard C,Mutter D,Marescaux J,Damgé C

更新日期：1994-01-01 00:00:00

abstract：UNLABELLED:This study examined the role of the gastric mucosal blood flow (MBF) in the gastric cytoprotection produced by prostacyclin (PGI2) and prostaglandin E2 (PGE2) in dogs. An acidified solution of saline was applied topically on the canine gastric mucosa with and without ethanol at various concentrations. Ethano...

journal_title：Digestion

authors： Konturek SJ,Robert A

更新日期：1982-01-01 00:00:00

abstract：:Cell renewal in the duodenal mucosa of Mastomys was studied by autoradiography 1 and 24 h after intraperitoneal injection of tritiated thymidine. Non-specific duodenitis and duodenal ulceration were produced with a continuous infusion of histamine. Mucosal renewal in the duodenum of 30 control Mastomys was compared wi...

journal_title：Digestion

authors： Smedley FH,Rimmer J,Samanidis A,Wastell C

更新日期：1990-01-01 00:00:00

abstract：:This study was undertaken to evaluate the effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients. Sixteen cirrhotics were randomly assigned to metoclopramide (10 mg i.v.) or saline. Metoclopramide significantly decreased transmural variceal pressure (15.7% decr...

journal_title：Digestion

authors： Taranto D,Suozzo R,de Sio I,Romano M,Caporaso N,Del Vecchio Blanco C,Coltorti M

更新日期：1990-01-01 00:00:00

abstract：:Neutrophil motility in normal subjects and Crohn's disease patients was assessed using both double and single filter assay systems with n-formylmethionylleucylphenylalanine (FMLP) as the attractant, and in a single filter assay with Candida albicans in 10% serum as the attractant. Assays were performed in triplicate a...

journal_title：Digestion

authors： Curran FT,Keighley MR

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Currently, use of the Bravo capsule is a very common method for evaluating the gastroesophageal reflux because it has the advantage of being an intraesophageal catheter-free system. However, endoscopic removal of the capsule is necessary when technical problems or severe discomfort are present. Most frequent...

journal_title：Digestion

authors： de Hoyos A,Esparza EA,Loredo ML

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Double-filtration plasmapheresis (DFPP) together with interferon (IFN) administration produces a substantial reduction in the viral load during the early stages of treatment. METHODS:Based on their responses to previous pegylated IFN and ribavirin (PEG-IFN/RBV) therapy, 20 patients were divided int...

journal_title：Digestion

authors： Kim SR,Saito J,Imoto S,Komaki T,Nagata Y,Kim KI,Sasase N,Kimura N,Sasatani K,Konishi E,Hasegawa Y,Fujinami A,Ohta M,El-Shamy A,Tanaka Y,Sugano M,Sakashita M,Nakamura A,Tsuchida S,Makino T,Kawada T,Nakajima T,M

更新日期：2011-01-01 00:00:00

abstract：:The ratio of 6beta-hydroxycortisol to 17-hydroxycorticosteroids in the urine of 73 patients with liver disease, and 53 controls has been measured. The mean ratio was significantly greater in the liver disease group (p less than 0.001), this elevation being most marked among patients with liver metastases and patients ...

journal_title：Digestion

authors： Eade OE,Maddison A,Leonard PJ,Wright R

更新日期：1977-01-01 00:00:00

abstract：:Effects of indomethacin on healed partially healed gastric ulcers in the dog were studied. Gastric ulcers were produced by submucosal injection of 1 ml of 40% acetic acid solution into the bordering area of the fundus and antrum of the stomach. Indomethacin, 20 mg/kg, was given orally once daily for 5 days beginning o...

journal_title：Digestion

authors： Okabe S,Tabata K

更新日期：1981-01-01 00:00:00

abstract：:The aim of the study was to define the effects of sex, age, smoking, alcohol, analgesic ingestion, and treatment method whereby healing was initially induced on the prognosis of patients with a chronic duodenal ulcer (DU). 122 patients were assessed 1 year after the endoscopic demonstration of a DU. Two outcome variab...

journal_title：Digestion

authors： Piper DW,McIntosh JH,Hudson HM

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:To investigate whether the neuronal form of nitric oxide (NO) synthase (nNOS) in gastric mucosa differed from nNOS in the brain in subcellular distribution or antigenicity, and to determine the relative activity of the endothelial form of NO synthase (eNOS) and nNOS in gastric mucosa. METHODS:Subcellul...

journal_title：Digestion

authors： Price K,Hanson P

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND/AIM:What naturally happens to patients after they undergo conservative and endoscopic treatment of colonic diverticular bleeding (CDB) is largely unknown. We retrospectively track the long-term outcome of the recurrence of CDB between patients with endoscopic and conservative treatment. METHODS:The group wa...

journal_title：Digestion

authors： Mizuki A,Tatemichi M,Nakazawa A,Tsukada N,Nagata H,Kanai T

更新日期：2016-01-01 00:00:00