Abstract:
:The urinary excretion rates of nitrate (NO3) and nitrite (NO2) were monitored in 14 patients with active ulcerative colitis during treatment using hydrocortisone and sulfasalazine. During the active phase of the disease, the NO3 excretion was significantly higher in the patients than in healthy controls (n = 6, p < 0.05), although it varied considerably among the patients. During the healing phase, the NO3 excretion decreased concurrently with improvement of symptoms and colorectal ulceration, but the NO2 excretion increased. During the inactive phase of the disease, the NO3 and NO2 excretions were significantly lower than during the active phase, and the NO2/NO3 ratio resembled that in the healthy controls. In contrast, a patient who failed to respond to treatment showed continuously high NO3 and NO2 excretion rates. These results indicate that urinary NO3 and NO2 excretions vary with the disease state in ulcerative colitis.
journal_name
Digestionjournal_title
Digestionauthors
Sasajima K,Yoshida Y,Yamakado S,Sato J,Miyashita M,Okawa K,Matsutani T,Onda M,Kawano Edoi
10.1159/000201332subject
Has Abstractpub_date
1996-01-01 00:00:00pages
170-3issue
3eissn
0012-2823issn
1421-9867journal_volume
57pub_type
杂志文章相关文献
DIGESTION文献大全abstract:BACKGROUND/AIMS:A trophic role of gastrin has been convincingly demonstrated in the oxyntic mucosa of the stomach, but is still a matter of debate in the lower gastrointestinal tract. METHODS:In order to examine the role of circulating gastrin in colorectal adenoma and carcinoma fasting serum gastrin concentrations we...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000007634
更新日期:1999-03-01 00:00:00
abstract::Sedation and analgesia is the standard of care during diagnostic and therapeutic endoscopic gastrointestinal procedures in most areas of the world. Unsedated endoscopy is feasible in selected patients, but requires commitment on the part of both the patient and the provider. The American Society of Anesthesiologists h...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000285504
更新日期:2010-01-01 00:00:00
abstract::Interdigestive motor activity has been studied extensively both in the human and canine small intestine. The more irregular postprandial pattern, however, has rarely been studied. In particular, physiological studies in humans are lacking. Thus it is unknown whether the physical state of a meal affects the duration of...
journal_title:Digestion
pub_type: 临床试验,杂志文章
doi:10.1159/000201474
更新日期:1997-01-01 00:00:00
abstract:AIMS:The primary objective of this study was to clarify the influence of histotype on the outcome of D1/D2 gastrectomized patients with pathologically proven R0 resection. The secondary objective was to demonstrate overall survival (OS), disease-free survival (DFS), and locoregional recurrence rates following standard ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000338298
更新日期:2012-01-01 00:00:00
abstract::A highly significant increase in net fluxes across the guinea-pig small intestine for both 45Ca2+ and 35SO4(2-), in the presence of cystic fibrosis plasma compared with non-cystic fibrosis plasma, was observed (p less than 0.001). In the presence of cystic fibrosis plasma, the nuclear, mitochondrial, microsomal and so...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199307
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND/AIMS:There are many reports of non-alcoholic fatty liver disease (NAFLD) patients with increased carotid intima-media thickness (IMT). However, there is little information about carotid IMT in alcoholic fatty liver disease (AFLD) patients. We aimed to compare the carotid IMT of NAFLD patients and AFLD patien...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000326854
更新日期:2011-01-01 00:00:00
abstract::Indicators of net water movement are used in a variety of intestinal transport studies. Such indicators should be virtually unabsorbed under study conditions. The effects of stimuli that alter intestinal mass on indicator recovery have not been examined. We used the male albino rat to study the effects of food restric...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199576
更新日期:1987-01-01 00:00:00
abstract::The clinical value of the tumor marker human chorionic gonadotropin-beta (hCG-beta) in ascitic fluid for the differentiation of malignancy-related and non-malignant ascites was evaluated. Ascitic fluid protein, cholesterol and cytological examination were determined for comparison. Thirty-six patients with malignancy-...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201324
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND/AIMS:Currently, a split-dose of polyethylene glycol (PEG) is the mainstay of bowel preparation due to its tolerability, bowel-cleansing action, and safety. However, bowel preparation with PEG is suboptimal because residual fluid reduces the polyp detection rate and requires a more thorough colon inspection. ...
journal_title:Digestion
pub_type: 杂志文章,随机对照试验
doi:10.1159/000339780
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:In this study, a clinical and serological follow-up of 8-10 years was performed in relatives of celiac disease (CD) patients from southern Brazil. The occurrence of new CD cases in the families and the use of two different IgA-tTG enzyme-linked immunosorbent assay (ELISA) kits were also evaluated. METH...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000320451
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/AIM:Previous studies have reported small intestinal lesions in patients with portal hypertensive disease. However, the etiology of these lesions is not clear, as portal venous pressure was not measured in any of these studies. The aim of this study is to clarify the association between small intestinal lesio...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000338180
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND AND AIM:Many investigations have demonstrated that changes in body weight are frequent in patients with coeliac disease (CD) after a gluten-free diet (GFD); conversely data on the metabolic syndrome (MS) and hepatic steatosis (HS) are still rare. The aim is to evaluate the prevalence of MS and HS in patients...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000495749
更新日期:2019-01-01 00:00:00
abstract::We studied the functional coupling between antral somatostatin and gastrin cells in pigs using isolated perfused preparations of the antrum with intact supply of the vagus nerves. Luminal acidification significantly inhibited gastrin secretion to 61 +/- 3% of basal secretion and increased somatostatin output 9-fold. I...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000200882
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Upper gastrointestinal bleeding (UGB) is an important precipitating factor for the development of hepatic encephalopathy (HE) in cirrhotic patients. The aim of this study was to evaluate the efficacy of lactulose in a controlled randomized trial for prophylaxis of HE after UGB. PATIENTS AND METHODS...
journal_title:Digestion
pub_type: 杂志文章,随机对照试验
doi:10.1159/000346083
更新日期:2013-01-01 00:00:00
abstract::The present study was undertaken to investigate the effect of adrenergic agents on secretion of amylase from the salivary glands in vivo. Saliva was collected from the distal oesophagus in conscious rats. Adrenaline increased the concentration of amylase in saliva and serum significantly. The result of infusion of alp...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199729
更新日期:1988-01-01 00:00:00
abstract::Eighteen cases of severe hyperplasia of fundic argyrophil cells observed during routine histologic examination of endoscopic gastric biopsy specimens from unselected patients with upper gastro-intestinal symptomatology were investigated. All patients, except one, were female with a mean age of 57 years. Atrophic gastr...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199389
更新日期:1986-01-01 00:00:00
abstract:AIMS:We investigated the effect of n-3 polyunsaturated fatty acids (PUFAs) on mucosal levels of leukotrienes (LTs) and lipid peroxide (LPO), and on mucosal microcirculation, in rats with experimental colitis induced by dextran sulfate sodium (DSS). METHODS:We fed Wistar rats a perilla oil-enriched diet containing alph...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000051872
更新日期:2001-01-01 00:00:00
abstract::Gastric emptying was measured in 12 patients with chronic duodenal ulceration and compared with the results from 10 healthy volunteers. The test meal of 300 ml 15% dextrose, labelled with 99mTc-DTPA, was ingested in increments over 6 min. Gamma camera imaging proceeded over 30 min, with a 1-min frame time. A direct co...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199660
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND/AIMS:Polyamine uptake from the circulation plays an important role in the maintenance of the intracellular polyamine content during extensive proliferation in intestinal mucosal cells. METHODS:Isolated basolateral membrane vesicles of the rabbit enterocyte were used to characterize polyamine transport acros...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000007468
更新日期:1998-01-01 00:00:00
abstract::Combining the narrow-band imaging (NBI) system and magnifying endoscopy allows simple and clear visualization of microscopic structures of the superficial mucosa and its capillary patterns, which may be useful for precise endoscopic diagnosis in the gastrointestinal tract, being more closely to histopathological diagn...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000321799
更新日期:2011-01-01 00:00:00
abstract::Outpatient treatment of haemorrhoids by elastic band ligation without anaesthetic was performed in 75 patients. Clinical review showed that 65 returned to work within 24 h of ligation, 8 in 48 h and 2 after 48 h. No patient required hospitalisation for either rectal bleeding or pain after ligation. In the first week a...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197658
更新日期:1975-01-01 00:00:00
abstract::OctreoTher ((90)Y-DOTA-D-Phe(1)-Tyr(3)-octreotide, a.k.a. (90)Y-SMT 487) consists of a somatostatin peptide analogue (Tyr(3)-octreotide), coupled with a complexing moiety (DOTA), and labeled with a tightly bound beta-emitter (yttrium-90). By targeting somatostatin receptor-positive tumors (as imaged by OctreaScan it m...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000051858
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Crohn's disease (CD) is a chronic immune-mediated disorder of the gastrointestinal tract. The pathophysiological understanding of this disease is limited and no curative therapy is available so far. Therefore, most patients require long-lasting or even life-long immunosuppressive therapies for the suppressio...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000488449
更新日期:2018-01-01 00:00:00
abstract::Rectal biopsies were maintained in organ culture over a 24-hour culture period, with good preservation of histological architecture. A filtrate containing Clostridium difficile toxin significantly inhibited the rise in epithelial alkaline phosphatase activity normally seen during culture. This effect was abolished by ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199212
更新日期:1985-01-01 00:00:00
abstract::Serum retinol and serum carotene concentrations were determined over a 6-month period in 137 outpatients with Crohn's disease. Serum retinol measurements were within the reference range for all patients at each assessment period, while serum carotene levels were low in about one quarter of the patients. Of the 56 pati...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000199495
更新日期:1987-01-01 00:00:00
abstract::The aim of this study was to evaluate the serum behavior of human pancreas-specific protein/procarboxypeptidase B (hPASP/PCPB) in the early phases of acute pancreatitis, and to calculate its sensitivity and specificity in comparison with those of serum amylase and lipase in the diagnosis of this illness. Twenty-six ac...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000201128
更新日期:1994-01-01 00:00:00
abstract::Intestinal absorption after extensive small bowel resections, for diseases other than Crohn's disease, was studied in 17 patients. When the ileocecal valve and the right colon were preserved, malabsorption was transient and moderate and had no prejudicial nutritional effect (fecal fat: 8.8 +/- 1.8 g/24 h in resections...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198220
更新日期:1978-01-01 00:00:00
abstract::Somatostatin is widely distributed throughout the human gastrointestinal system. There it is found in neurons and fibers of both the submucosal and the myenteric plexus and the pancreas as well as in the D cells of the stomach, gut and pancreatic islets. Whereas in the intestinal nervous system, in the duodenum and th...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000201070
更新日期:1993-01-01 00:00:00
abstract::Worldwide viral hepatitis is the most common cause of jaundice, chronic liver disease cirrhosis and hepatocellular carcinoma. While important advances have been made in prevention of viral hepatitis, therapy of this disease remains unsatisfactory. There are no specific therapies of proven benefit for acute hepatitis, ...
journal_title:Digestion
pub_type: 杂志文章,评审
doi:10.1159/000007532
更新日期:1998-08-01 00:00:00
abstract::Gastrinomas may occur in the pancreas, duodenum or peripancreatic lymph nodes. The gastrin overproduction leads to the Zollinger-Ellison syndrome with multiple gastric and duodenal ulcers and diarrhea. About two thirds of gastrinomas are malignant. Diagnosis is made by clinical history, gastroscopy, and measurement of...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000122229
更新日期:2008-01-01 00:00:00