Terminal-restriction fragment length polymorphism (T-RFLP) analysis for changes in the gut microbiota profiles of indomethacin- and rebamipide-treated mice.

abstract：:Administration of cholic acid (1.0% of the diet) to male Fisher rats for 3 days resulted in increased numbers of DNA synthesizing epithelial cells per colonic crypt column as compared to those found in either control or 0.2% cholic acid-fed rats. The middle third of the crypt was the area stimulated to contribute the ...

journal_title：Digestion

authors： Deschner EE,Cohen BI,Raicht RF

更新日期：1981-01-01 00:00:00

abstract：:The influence of CDCA and UDCA administration on human intestinal permeability to lactulose, as disclosed by intravenous CCK, has been investigated. For this purpose the fraction of lactulose excreted in the urine during 5 h after an oral load of the disaccharide in hypertonic solution was measured in 12 healthy subje...

journal_title：Digestion

authors： Budillon G,Parrilli G,Capuano G,Mazzacca G,Menzies IS

更新日期：1982-01-01 00:00:00

abstract：:The effect of maximal doses of cholecystokinin and caerulein on lipase and chymotropsin concentrations were compared in large groups of patients with almost equal capacities of bicarbonate secretion. The responsiveness of the pancreas is, as a whole, higher with caerulein than with cholecystokinin, this feature being ...

journal_title：Digestion

authors： Minaire Y,Descos L

更新日期：1977-01-01 00:00:00

abstract：:An improved GLC method was employed to study individual serum bile acids in 14 control subjects after a 12-hour fast followed by a standard fatty meal. Peripheral venous blood samples were obtained at 15-min intervals for up to 2 h in 7 subjects, and 4 h in 2 subjects. The fasting total bile acids, and cholic:chenodeo...

journal_title：Digestion

authors： Pennington CR,Ross PE,Bouchier IA

更新日期：1978-01-01 00:00:00

abstract：:The purpose of this study was to determine the regulation of pancreatic polypeptide (PP) release by using pirenzepine (a specific M1 muscarinic receptor antagonist), 4-diphenylacetoxy-N-methylpiperidine methobromide (4-DAMP, a specific M3 muscarinic receptor antagonist), atropine (a nonspecific muscarinic receptor ant...

journal_title：Digestion

authors： Tanikawa M,Hayakawa T,Kondo T,Naruse S,Shibata T,Kitagawa M

更新日期：1994-01-01 00:00:00

abstract：:CCK-8, bombesin, secretin and urecholine added in various concentrations to the incubation medium of the dispersed pancreatic acini, obtained from rats, resulted in a dose-dependent stimulation of amylase secretion, the half-maximal response being achieved at 3 X 10(-12), 10(-10), 10(-7) and 10(-5) M, respectively. Pi...

journal_title：Digestion

authors： Jaworek J,Konturek SJ

更新日期：1987-01-01 00:00:00

abstract：:Lithium is a cation which has central nervous system effects and is able to interfere with both the release and action of polypeptide hormones. We examined its effect on basal and stimulated plasma gastrin and pancreatic polypeptide (PP) levels in 4 dogs with chronic gastric fistulas. Gastrin and PP release were stimu...

journal_title：Digestion

authors： Modlin IM,Ehrlich BE,Lamers CB,Diamond JM,Walsh JH

更新日期：1981-01-01 00:00:00

abstract：:A 3 years evolution with amyloid involvement, primarily of the liver, in a patient is described. This led to intrahepatic cholestasis and to portal hypertension with esophageal varices. ...

journal_title：Digestion

authors： Melkebeke P,Vandepitte J,Hannon R,Fevery J

更新日期：1980-01-01 00:00:00

abstract：:Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional cytokine which modifies tissue stromal matrix synthesis, cell proliferation and immune function. In the present study, we have used a mouse monoclonal antibody to the latent (intracytoplasmic) form of TGF-beta 1 to compare its expression in 144 cases ...

journal_title：Digestion

authors： Slater SD,Williamson RC,Foster CS

更新日期：1995-01-01 00:00:00

abstract：:Recent progress in both basic and clinical research has led us to develop sophisticated and effective medical therapy of ulcerative colitis (UC). Although classical agents such as aminosalicylates, corticosteroids and immunomodulatory drugs have remained as the gold standard for decades, their novel formulations and/o...

journal_title：Digestion

authors： Nakamura T,Nagahori M,Kanai T,Watanabe M

更新日期：2008-01-01 00:00:00

abstract：:Recent studies indicate that intestinal lamina propria T cells are highly specialized lymphocytes, which differ from T cells in other compartments of the immune system in several respects. In the present study phenotypic and functional characteristics of lamina propria T cells and their possible relation to mucosal gr...

journal_title：Digestion

authors： Zeitz M,Schieferdecker HL,James SP,Riecken EO

更新日期：1990-01-01 00:00:00

abstract：:The interactions of adrenergic and cholinergic influences on the gastric D cell were studied using an isolated perfused rat stomach in vitro. The sevenfold increase in the release of somatostatin-like immunoreactivity (SLI) in response to isoproterenol (4 . 10(-8) M) was dose-dependently inhibited by acetylcholine (10...

journal_title：Digestion

authors： Koop H,Behrens I,Bothe E,McIntosh CH,Pederson RA,Arnold R,Creutzfeldt W

更新日期：1982-01-01 00:00:00

abstract：:The aim of this study was to examine the relative importance of the enzymes ornithine decarboxylase (ODC) and diamine oxidase (DAO) in intestinal polyamine metabolism in normal rats. To study this we measured jejunal and ileal DAO and ODC activities and polyamine levels 2 h after injecting, in non-fasting male Wistar ...

journal_title：Digestion

authors： Rokkas T,Vaja S,Taylor P,Murphy GM,Dowling RH

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Overt hepatic encephalopathy (HE) following insertion of a transjugular intrahepatic portosystemic shunt (TIPS) is a problem in some patients. In contrast to overt HE, minimal HE (MHE) following TIPS is studied to a limited degree only. We therefore evaluated the incidence of MHE in patients following TIPS i...

journal_title：Digestion

authors： Biecker E,Hausdörfer I,Grünhage F,Strunk H,Sauerbruch T

更新日期：2011-01-01 00:00:00

abstract：:A 14C-triolein breath test was carried out on 49 subjects suffering from chronic pancreatitis or from other digestive diseases, and its results were compared with the daily fecal fat excretion. The 14CO2 peak excretion was abnormal in all the subjects with a fecal fat excretion above 14 g/day, whereas individual value...

journal_title：Digestion

authors： Benini L,Scuro LA,Menini E,Manfrini C,Vantini I,Vaona B,Brocco G,Talamini G,Cavallini G

更新日期：1984-01-01 00:00:00

abstract：:A statistical study was carried out to determine if fasting serum bile acid levels are clinically useful in differentiating children with chronic persistent hepatitis from children with chronic aggressive hepatitis. Serum bile acid levels were determined in 27 patients with chronic aggressive hepatitis, 41 with chroni...

journal_title：Digestion

authors： Jara P,Codoceo R,Hernanz A,Castaño C,Diaz C,Montero JL,Vázquez C

更新日期：1983-01-01 00:00:00

abstract：:This prospective study was designed to validate a novel biopsy urease test as well as a simplified 13C-urea breath test for the detection of Helicobacter pylori. In addition, the hypothesis was tested that both the reaction velocity of the urease test and the 13CO2 excess of the urea breath test may allow a prediction...

journal_title：Digestion

authors： Labenz J,Bärsch G,Peitz U,Aygen S,Hennemann O,Tillenburg B,Becker T,Stolte M

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:There are unexpectedly large differences between the incidences of acute pancreatitis (AP) as indicated by different hospitals. Retrospective studies suggest that the reason behind this is the large differences that exist between the local managements of abdominal pain at emergency units. Unfortunately, no e...

journal_title：Digestion

authors： Zsoldos F,Párniczky A,Mosztbacher D,Tóth A,Lásztity N,Hegyi P,Hungarian Pancreatic Study Group and the International Association of Pancreatology.

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIM:Studies have demonstrated an important role for endogenous PG and NO in the healing of chronic gastric ulcers. We investigated the effects of COX and NOS inhibitors on the healing of duodenal ulcers, in comparison with gastric ulcers, in rats. METHODS:Gastric and duodenal ulcers were induced by serosal ...

journal_title：Digestion

authors： Araki H,Komoike Y,Matsumoto M,Tanaka A,Takeuchi K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Since resistance of Helicobacter pylori is developing very fast all over the world, new treatment regimens for eradication are urgently needed. AIM:To compare eradication success rate of H. pylori treatment regimens with and without doxycycline. METHODS:English medical literature searches were conducted fo...

journal_title：Digestion

authors： Niv Y

更新日期：2016-01-01 00:00:00

abstract：AIMS:We investigated the effect of n-3 polyunsaturated fatty acids (PUFAs) on mucosal levels of leukotrienes (LTs) and lipid peroxide (LPO), and on mucosal microcirculation, in rats with experimental colitis induced by dextran sulfate sodium (DSS). METHODS:We fed Wistar rats a perilla oil-enriched diet containing alph...

journal_title：Digestion

authors： Shimizu T,Igarashi J,Ohtuka Y,Oguchi S,Kaneko K,Yamashiro Y

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Recently, minimally invasive approaches such as endoscopic treatment or laparoscopic gastrectomy for early gastric cancer have made rapid progress. However, the extent of gastrectomy and lymphadenectomy in laparoscopic surgery is radical, similar to that of open gastrectomy for patients with early gastric ca...

journal_title：Digestion

authors： Hiramatsu Y,Takeuchi H,Goto O,Kikuchi H,Kitagawa Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:The benefits of colonoscopy in reducing colorectal cancer (CRC) risk for patients over 75 years are controversial. We aimed to determine whether colonoscopy use is associated with a decreased risk of CRC in patients 76-85 years old in the United States (US). PATIENTS AND METHODS:All patients in the Med...

journal_title：Digestion

authors： Wang YR,Cangemi JR,Loftus EV Jr,Picco MF

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Colonic endoscopic mucosal resection (EMR) is safe for patients without antithrombotic therapy; however, EMR is associated with several risks. This study was performed to evaluate the risk of delayed hemorrhage in patients undergoing EMR without antithrombotic therapy. METHODS:In the present retrospect...

journal_title：Digestion

authors： Tsuruta S,Tominaga N,Ogata S,Tsuruoka N,Sakata Y,Shimoda R,Eguchi Y,Anzai K,Hara M,Fujimoto K

更新日期：2019-01-01 00:00:00

abstract：:We have shown that dietary long-chain triglycerides and 16,16-dimethyl prostaglandin E2 enhance and aspirin impairs postresection mucosal adaptation in rats. The present studies examined the hypothesis that supplemental linoleic acid (LA) above the minimum requirement may enhance postresection mucosal adaptation throu...

journal_title：Digestion

authors： Park JH,Grandjean CJ,Hart MH,Baylor JM,Vanderhoof JA

更新日期：1989-01-01 00:00:00

abstract：:This study examined the morphological and functional adaptations occurring in the jejunum of adult rats fed totally by parenteral nutrition during a 4-day period. Comparison was made with sham-operated animals receiving orally a similar isocaloric diet. The intravenously fed rats exhibited a 20% shortening of the vill...

journal_title：Digestion

authors： Raul F,Galluser M,Doffoel M

更新日期：1984-01-01 00:00:00

abstract：:The luminal mucus layer of the rat's small intestine was separated from the mucosa by filling the lumen with agar jelly. When the rats were fasted overnight and given 59Fe or 65Zn by stomach tube the mucus isolated by this technique contained more isotope and more sialic acid than fed controls, and more of the isotope...

journal_title：Digestion

authors： Quarterman J

更新日期：1987-01-01 00:00:00

abstract：:The current therapy of choice for all Helicobacter pylori-associated ulcer disease is eradication therapy. Although adequate therapeutic regimens are currently available, often still ineffective therapies are tried. Cure of the infection essentially eliminates the ulcer diathesis. Cure of the infection is especially i...

journal_title：Digestion

authors： Tytgat GN

更新日期：1998-08-01 00:00:00

abstract：:The incidence of steatorrhea is said to be lower and its grade milder in Japanese because their fat intake is lower than that of Europeans and Americans. Failure to take this into account creates difficulties when attempting to compare data on pancreatic exocrine insufficiency in different countries. The authors exami...

journal_title：Digestion

authors： Nakamura T,Tando Y,Yamada N,Watanabe T,Ogawa Y,Kaji A,Imamura K,Kikuchi H,Suda T

更新日期：1999-01-01 00:00:00

abstract：:23 cirrhotics with ascites and sodium retention, whose aldosteronemia had been evaluated after an equilibration period at controlled sodium intake at the occasion of previous studies, were retrospectively investigated. The dosage of spironolactone needed to induce a negative sodium balance correlated significantly wit...

journal_title：Digestion

authors： Bernardi M,Servadei D,Trevisani F,Rusticali AG,Gasbarrini G

更新日期：1985-01-01 00:00:00