Obesity, metabolic syndrome and the risk of development of colonic diverticulosis.

abstract：BACKGROUND/AIMS:This study aimed at (i) clarifying the factors associated with high scores on the modified frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) among 3,505 relatively healthy subjects undergoing routine medical health checkups with gastrointestinal endoscopy and (ii) comparing risk...

journal_title：Digestion

authors： Takeshita E,Sakata Y,Hara M,Akutagawa K,Sakata N,Endo H,Ohyama T,Matsunaga K,Yoshioka T,Kawakubo H,Tanaka Y,Shirai S,Ito Y,Tsuruoka N,Iwakiri R,Kusano M,Fujimoto K

更新日期：2016-01-01 00:00:00

abstract：:The serine protease inhibitor camostate (Foy-305; 200 mg/kg body weight) had been administered twice daily either subcutaneously or orally to mice for 5, 10 and 15 days. Within 5 days, pancreatic weight, concentration of trypsin, amylase and protein were significantly increased and even more increased after 10 and 15 ...

journal_title：Digestion

authors： Wereszczyńska-Siemiatkowska U,Pohl U,Otto J,Lankisch PG

更新日期：1987-01-01 00:00:00

abstract：:The effect of the long-acting somatostatin analogue Sandostatin (SMS 201-995) on intestinal absorption and propagation (mouth-to-caecum transit time; MCTT), on pancreatic secretion and on gall bladder contraction after direct (secretin-pancreozymin test) and indirect stimulation (Lundh meal), and on meal-induced respo...

journal_title：Digestion

authors： Lembcke B,Creutzfeldt W,Schleser S,Ebert R,Shaw C,Koop I

更新日期：1987-01-01 00:00:00

abstract：:In chronic pancreatitis the exocrine pancreatic tissue is replaced by extracellular matrix deposits from fibroblasts. We have stimulated fibrogenesis in the pancreas by inducing a single episode of cerulein pancreatitis (10 microg/kg/h for 12 h). We have used a spectrophotometrical assay to measure the tissue hydroxyp...

journal_title：Digestion

authors： Weidenbach H,Lerch MM,Turi S,Bachem M,Adler G

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to see whether administration of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, could prevent the development of gastric cancer via inhibition of apurinic/apyrimidinic endonuclease-1 (APE-1) expression induced by Helicobacter pylori infection. METHODS:70 Mongol...

journal_title：Digestion

authors： Futagami S,Kawagoe T,Horie A,Shindo T,Hamamoto T,Suzuki K,Kusunoki M,Miyake K,Gudis K,Tsukui T,Crowe SE,Sakamoto C

更新日期：2008-01-01 00:00:00

abstract：:Saliva from one parotid gland was collected under citric acid stimulation in three groups consisting of 69 control subjects and two groups consisting of 25 patients with chronic and relapsing chronic pancreatitis. Mixed saliva was collected under mechanical stimulation from 10 patients and 6 control subjects. Flow rat...

journal_title：Digestion

authors： Dürr GH,Amouric M,Bode C,Bode JC,Sarles H,Figarella C

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Duodenal cancer is one of the extracolonic malignancies with known mortality in familial adenomatous polyposis (FAP) patients. Visualization of the major duodenal papilla (MDP) with a standard esophagogastroduodenoscopy (EGD) is currently insufficient because of the limited field of view. Full-spect...

journal_title：Digestion

authors： Ichijima R,Abe S,Kobayashi S,Minagawa T,Tagawa T,Nakajima T,Yamada M,Takamaru H,Sekiguchi M,Sakamoto T,Oda I,Matsuda T,Saito Y,Gotoda T

更新日期：2020-01-01 00:00:00

abstract：:CCK-8, bombesin, secretin and urecholine added in various concentrations to the incubation medium of the dispersed pancreatic acini, obtained from rats, resulted in a dose-dependent stimulation of amylase secretion, the half-maximal response being achieved at 3 X 10(-12), 10(-10), 10(-7) and 10(-5) M, respectively. Pi...

journal_title：Digestion

authors： Jaworek J,Konturek SJ

更新日期：1987-01-01 00:00:00

abstract：:Germ-free and conventional rats were fed a semi-synthetic diet including 10% wheat bran for 1 month. They were compared to similar rats fed the same diet without bran. Transit of polyethylene glycol (PEG) 4000 was studied in giving the marker either in saline or in the diet. The presence of a bacterial flora was found...

journal_title：Digestion

authors： Riottot M,Sacquet E,Leprince C

更新日期：1984-01-01 00:00:00

abstract：:We consider the multiple interacting factors which lead to the proliferation of human gastric enterochromaffin-like (ECL) cells, and control of this proliferation by somatostatin and its analogues. Somatostatin receptors occur in human fundic mucosa, and octreotide can be considered a useful therapeutic tool to contro...

journal_title：Digestion

authors： Delle Fave G,Annibale B

更新日期：1996-01-01 00:00:00

abstract：:Studies with short-term administration of omeprazole in patients with erosive or ulcerative reflux oesophagitis have demonstrated that strong inhibition of gastric acid secretion will become the therapy of choice for these patients. However, because reflux oesophagitis relapses rapidly when short-term treatment is dis...

journal_title：Digestion

authors： Jansen JB,Lamers CB

更新日期：1989-01-01 00:00:00

abstract：:The effects of secretin and caerulein on the absorption of water, sodium, potassium and glucose from the jejunum of dogs were investigated. Intravenous infusion of 1 clinical unit (CU; 82 pmol/kg/h) of secretin inhibited jejunal absorption of water, sodium and glucose compared to control period. Adding an intravenous ...

journal_title：Digestion

authors： Hirose S,Shimazaki K,Hattori N

更新日期：1986-01-01 00:00:00

abstract：:The effects of gastric fundectomy and antrectomy on the colonic mucosa were studied in hamsters over 5 and 25 days. Sham-operated animals served as controls. Basal plasma gastrin concentrations were significantly increased after fundectomy and significantly decreased after antrectomy. Five days after fundectomy, there...

journal_title：Digestion

authors： Chu M,Rehfeld JF,Borch K

更新日期：1992-01-01 00:00:00

abstract：:The effects of two recently developed gastrin receptor antagonists, PD 136450 and L-365,260, on pentagastrin-stimulated acid secretion were investigated in rats. PD 136450 at a dose of 6 mg/kg s.c. (9.6 mumol) completely abolished acid secretion induced by pentagastrin. The inhibition of 18 mg/kg PD 136450 s.c. lasted...

journal_title：Digestion

authors： Eissele R,Koop H,Bothe-Sandfort E,Arnold R

更新日期：1992-01-01 00:00:00

abstract：INTRODUCTION:The incidence of early-onset inflammatory bowel disease is increasing in Japan. OBJECTIVE:This study aimed to analyze the treatment and progress of early-onset inflammatory bowel disease. METHODS:This prospective survey evaluated the data of 43 patients aged <8 years who were diagnosed with inflammatory ...

journal_title：Digestion

authors： Kudo T,Fujii T,Maisawa SI,Sasaki M,Uchida K,Ida S,Kagimoto S,Yoden A,Shimizu T

更新日期：2020-05-18 00:00:00

abstract：:D-Galactosamine administration to rats (400 mg/kg) by intraperitoneal injection induced biochemical alterations in liver plasma membranes. Alterations were studied 4, 16 and 24 h after D-galactosamine injection. Plasma membrane 5'-mononucleotidase activity decreased to 40% of control values. Carbohydrate composition w...

journal_title：Digestion

authors： Bertrand F,Veissiere D,Picard J

更新日期：1979-01-01 00:00:00

abstract：:Activation of enzyme phospholipase A2 (EC 3.1.1.4), the major liberator of arachidonic acid, has been proposed as a component in the pathogenesis of inflammatory bowel disease. To test the hypothesis that phospholipase A2 activity is increased in ulcerative colitis, enzyme activity was investigated in colonic biopsies...

journal_title：Digestion

authors： Almer S,Franzén L,Olaison G,Smedh K,Ström M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy for advanced gastric cancer is expected to improve prognoses. However, as there is no method to evaluate neoadjuvant chemotherapeutic efficacy before gastrectomy, some patients at high risk for a poor prognosis undergo gastrectomy. The aim of the present study was to investigate whet...

journal_title：Digestion

authors： Sugawara N,Ota K,Terazawa T,Tanaka R,Akutagawa H,Yamaguchi T,Imai Y,Harada S,Kojima Y,Tashiro K,Kii T,Lee SW,Kawai M,Egashira Y,Goto M,Uchiyama K,Hirose Y,Takeuchi T,Higuchi K

更新日期：2020-01-01 00:00:00

abstract：:The aim of the study was to define the effects of sex, age, smoking, alcohol, analgesic ingestion, and treatment method whereby healing was initially induced on the prognosis of patients with a chronic duodenal ulcer (DU). 122 patients were assessed 1 year after the endoscopic demonstration of a DU. Two outcome variab...

journal_title：Digestion

authors： Piper DW,McIntosh JH,Hudson HM

更新日期：1985-01-01 00:00:00

abstract：:Prostacyclin, its stable metabolite 6-keto-prostaglandin F1 alpha and prostaglandin E2 were tested on the adenylate cyclase system in human gastric mucosa. All three compounds were able to activate human cyclase. Saturating concentrations of prostacyclin, prostaglandin E2 and 6-keto-prostaglandin F1 alpha (each 0.28 m...

journal_title：Digestion

authors： Simon B,Kather H

更新日期：1979-01-01 00:00:00

abstract：:We report on a 39-year-old woman suffering from deep venous thrombosis due to a heterozygous factor-V-Leiden mutation with resistance to activated protein C. Four months after beginning oral anticoagulation, generalized jaundice appeared. Subsequently, subacute liver failure developed necessitating an orthotopic liver...

journal_title：Digestion

authors： Mix H,Wagner S,Böker K,Gloger S,Oldhafer KJ,Behrend M,Flemming P,Manns MP

更新日期：1999-11-01 00:00:00

abstract：INTRODUCTION:Colonic motility disorders are a frequent clinical problem caused by various drugs and diseases. However, the etiology of colonic dysmotility is often unclear due to the lack of in vivo methods, including rapid dynamic assessment. OBJECTIVES:The aim of this study was to establish a novel quantitative meth...

journal_title：Digestion

authors： Kishi K,Kaji N,Tsuru Y,Hori M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Recently, minimally invasive approaches such as endoscopic treatment or laparoscopic gastrectomy for early gastric cancer have made rapid progress. However, the extent of gastrectomy and lymphadenectomy in laparoscopic surgery is radical, similar to that of open gastrectomy for patients with early gastric ca...

journal_title：Digestion

authors： Hiramatsu Y,Takeuchi H,Goto O,Kikuchi H,Kitagawa Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Currently, use of the Bravo capsule is a very common method for evaluating the gastroesophageal reflux because it has the advantage of being an intraesophageal catheter-free system. However, endoscopic removal of the capsule is necessary when technical problems or severe discomfort are present. Most frequent...

journal_title：Digestion

authors： de Hoyos A,Esparza EA,Loredo ML

更新日期：2009-01-01 00:00:00

abstract：:Malabsorption syndromes are commonly caused by pathological interferences of normal digestive processes. In the last several years major advances in the diagnosis and treatment of these syndromes has emerged. This review will focus on diseases in which the mucosal phase of the digestive process is predominately distur...

journal_title：Digestion

authors： Sun DF,Fang JY

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Since resistance of Helicobacter pylori is developing very fast all over the world, new treatment regimens for eradication are urgently needed. AIM:To compare eradication success rate of H. pylori treatment regimens with and without doxycycline. METHODS:English medical literature searches were conducted fo...

journal_title：Digestion

authors： Niv Y

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:While probiotic bacteria are successfully used in the treatment of ulcerative colitis, the effect of commercially available probiotic products is still controversial. Here, we study whether the number of living probiotic bacteria in yoghurts is altered by an interruption of the cold chain. METHODS:Thre...

journal_title：Digestion

authors： Scharl M,Geisel S,Vavricka SR,Rogler G

更新日期：2011-01-01 00:00:00

abstract：:Effects of indomethacin on healed partially healed gastric ulcers in the dog were studied. Gastric ulcers were produced by submucosal injection of 1 ml of 40% acetic acid solution into the bordering area of the fundus and antrum of the stomach. Indomethacin, 20 mg/kg, was given orally once daily for 5 days beginning o...

journal_title：Digestion

authors： Okabe S,Tabata K

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVES:Few prospective population-based studies have been carried out on the incidence of inflammatory bowel disease (IBD). In a population-based study of pediatric IBD in southeastern Norway, patients <16 years at the time of diagnosis were followed up prospectively. The study reports on changes in diagnosis and c...

journal_title：Digestion

authors： Størdal K,Jahnsen J,Bentsen BS,Moum B

更新日期：2004-01-01 00:00:00

abstract：:Gastrinomas may occur in the pancreas, duodenum or peripancreatic lymph nodes. The gastrin overproduction leads to the Zollinger-Ellison syndrome with multiple gastric and duodenal ulcers and diarrhea. About two thirds of gastrinomas are malignant. Diagnosis is made by clinical history, gastroscopy, and measurement of...

journal_title：Digestion

authors： Granberg D,Jacobsson H,Oberg K,Gustavsson J,Lehtihet M

更新日期：2008-01-01 00:00:00