Abstract:
:Beard's theory can be restated in a modified form in modern terms in the following way. Cancer represents primarily trophoblastic tissue derived either from an aberrant germ cell or from a somatic cell whose normally repressed 'asexual generation' genes are abnormally reactivated ('derepressed'). The variety of tumors, other than teratomas, may be due to a parallel chance derepression of some genes of somatic ('sexual gneration') characters. This would be a defensive reaction against intramural parasitization by trophoblast and would result in the differentiation and hyperplasia of normally present more primative somatic cells.
journal_name
Oncologyjournal_title
Oncologyauthors
Gurchot Cdoi
10.1159/000225037subject
Has Abstractpub_date
1975-01-01 00:00:00pages
310-33issue
5-6eissn
0030-2414issn
1423-0232journal_volume
31pub_type
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