Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.

abstract：:The serum detection of S100B, a new melanoma marker, has shown clinical significance in early studies. The aim of our study of 1, 339 serum samples from 412 different melanoma patients and 107 control patients was to prove the prognostic value of serum S100B levels in melanoma patients at different stages of disease a...

journal_title：Oncology

authors： Hauschild A,Engel G,Brenner W,Gläser R,Mönig H,Henze E,Christophers E

更新日期：1999-01-01 00:00:00

abstract：:Thirteen samples of gastric tumors that had developed in the remnant stomach (remnant gastric cancer) were compared with 63 samples of primary gastric tumors located in the upper third of the stomach (primary gastric cancer) by both clinicopathologic and flow cytometric analysis. The depths of invasion of all these tu...

journal_title：Oncology

authors： Ikeguchi M,Kondou A,Oka A,Tsujitani S,Maeta M,Kaibara N

更新日期：1995-03-01 00:00:00

abstract：:Sorafenib, an oral multikinase inhibitor, has demonstrated clinical efficacy in patients with advanced hepatocellular carcinoma (HCC). However, in the SHARP trial (Sorafenib HCC Assessment Randomized Protocol trial) and the Asia-Pacific trial (conducted in the Asia-Pacific region), no cases of complete response (CR) w...

journal_title：Oncology

authors： Inuzuka T,Nishikawa H,Sekikawa A,Takeda H,Henmi S,Sakamoto A,Saito S,Kita R,Kimura T,Osaki Y,Kudo M

更新日期：2011-01-01 00:00:00

abstract：:After nearly four decades of clinical experience with the fluoropyrimidines, 5-fluorouracil (5-FU) remains an integral part of chemotherapy for colorectal cancer. A range of 5-FU treatment regimens with or without biochemical modulation are currently used and toxicity appears to be schedule dependent. The use of oral ...

journal_title：Oncology

authors： Brito RA,Medgyesy D,Zukowski TH,Royce ME,Ravandi-Kashani F,Hoff PM,Pazdur R

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:We retrospectively investigated the treatment outcomes of second-line treatment with pazopanib or gemcitabine/docetaxel in patients with advanced soft tissue sarcoma (STS). METHODS:Ninety-one patients who were treated with pazopanib or gemcitabine/docetaxel for advanced STS between 1995 and 2015 were analyz...

journal_title：Oncology

authors： Kim JH,Park HS,Heo SJ,Kim SK,Han JW,Shin KH,Kim SH,Hur H,Kim KS,Choi YD,Kim S,Lee YH,Suh JS,Ahn JB,Chung HC,Noh SH,Rha SY,Kim HS

更新日期：2019-01-01 00:00:00

abstract：:C-reactive protein (CRP) has been found to be ubiquitous in sera when determined by a highly sensitive methods such as radioimmunoassay. Patients with some tumors appear to have much higher serum levels of CRP than others; in these, CRP seems to reflect the tumor burden. There is a positive correlation with TNM stagin...

journal_title：Oncology

authors： Drahovsky D,Dunzendorfer U,Ziegenhagen G,Drahovsky M,Kellen JA

更新日期：1981-01-01 00:00:00

abstract：:In 29 patients (48 courses of chemotherapy), a randomized double-blind crossover study was undertaken to establish the antiemetic effectiveness of a combination of metoclopramide at a moderately high dose (5 mg/kg body weight) with 1 g methylprednisolone (treatment A) as compared with metoclopramide monotherapy (5 mg/...

journal_title：Oncology

authors： Ell C,König HJ,Brockmann P,Domschke S,Domschke W

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:Our aim was to assess FDG-PET/CT as a surrogate biomarker of the pathological complete response in locally advanced rectal cancer treated with neoadjuvant chemoradiation. METHODS:T3-4 and/or N+ rectal cancer patients were treated prospectively with capecitabine-based chemoradiation and total mesorectal exci...

journal_title：Oncology

authors： Bampo C,Alessi A,Fantini S,Bertarelli G,de Braud F,Bombardieri E,Valvo F,Crippa F,Di Bartolomeo M,Mariani L,Milione M,Biondani P,Avuzzi B,Chiruzzi C,Pietrantonio F

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:In order to improve the prognosis of pancreatic cancer patients, it is crucial to explore novel tools for its early diagnosis. Here, we attempted to screen serum biomarkers to distinguish pancreatic cancer from non-cancer individuals. METHODS:47 serum samples from pancreatic cancer patients, 39 of whom had s...

journal_title：Oncology

authors： Yu Y,Chen S,Wang LS,Chen WL,Guo WJ,Yan H,Zhang WH,Peng CH,Zhang SD,Li HW,Chen GQ

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:There is no standard second-line therapy for patients with oesophagogastric cancer who progress following first-line chemotherapy for advanced disease or relapse following radical multi-modality therapy. The aim of this retrospective study was to evaluate survival following rechallenge with platinum plus fluoro...

journal_title：Oncology

authors： Okines AF,Asghar U,Cunningham D,Ashley S,Ashton J,Jackson K,Hawkes E,Chau I

更新日期：2010-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is characterized as a highly chemoresistant cancer with no effective systemic therapy. Despite surgical or locoregional therapies, prognosis remains poor because of high tumor recurrence or tumor progression, and currently there are no well-established effective adjuvant therapies. The m...

journal_title：Oncology

authors： Pang RW,Poon RT

更新日期：2007-01-01 00:00:00

abstract：:Twelve patients with advanced primary lung cancers associated with malignant pleural effusion were treated with intrathoracic instillation of recombinant interleukin-2 with or without in-vitro-sensitized cells. Two cases achieved complete response, and 7 partial response. The adverse effects seen in the protocol were ...

journal_title：Oncology

authors： Miyao H,Chou T,Ito K,Moriyama H,Mitsuma S,Wakabayashi M,Yoshizawa H,Arakawa M

更新日期：1994-01-01 00:00:00

abstract：:Breast cancer is the most common cancer in women. Although survival rates have improved with the use of new therapeutic agents, many issues remain unresolved and new predictive and prognostic factors are needed in clinical practice. Several studies have suggested a prognostic and predictive role for circulating and di...

journal_title：Oncology

authors： Amadori A,Rossi E,Zamarchi R,Carli P,Pastorelli D,Jirillo A

更新日期：2009-01-01 00:00:00

abstract：:The effects on gastric and duodenal mucosa induced by cisplatin plus etoposide (PE) chemotherapy were investigated in 32 patients with lung cancer. They were submitted to gastroduodenoscopy before receiving cisplatin 100 mg/m2 (day 1) plus etoposide at a mean dose of 107 mg/m2 (days 1, 3 and 5). Endoscopic examination...

journal_title：Oncology

authors： Sartori S,Nielsen I,Maestri A,Beltrami D,Trevisani L,Pazzi P

更新日期：1991-01-01 00:00:00

abstract：:Several reports have demonstrated an adverse effect of perioperative blood transfusions on the survival of patients with various solid tumors treated surgically. We retrospectively investigated the relationship between perioperative blood transfusions and the survival of 501 patients who underwent radical subtotal gas...

journal_title：Oncology

authors： Choi JH,Chung HC,Yoo NC,Lee HR,Lee KH,Kim JH,Roh JK,Min JS,Lee KS,Kim BS

更新日期：1995-03-01 00:00:00

abstract：PURPOSE:Patient nonadherence to oral antineoplastic therapy is a well-recognized barrier to effective treatment. In order to identify patients who may need additional support to become adherent, it is important to have a useful tool that takes into account all the parameters of adherence to prescription. The aim of thi...

journal_title：Oncology

authors： Thivat E,Van Praagh I,Belliere A,Mouret-Reynier MA,Kwiatkowski F,Durando X,Mahammedi H,Dillies AF,Chollet P,Chevrier R

更新日期：2013-01-01 00:00:00

abstract：:Cases are presented in which 111In-bleomycin accumulated in Virchow's gland metastasis from squamous cell carcinoma of the uterine cervix, and in paratracheal lymphatic gland metastasis from embryonal carcinoma of the right ovary. Thus, this radiopharmaceutical was found to be of great use for assessment of metastatic...

journal_title：Oncology

authors： Kida T,Ikeda M

更新日期：1986-01-01 00:00:00

abstract：:Three lung tumor-associated markers (LTAM), previously identified as a Cohn Fraction IV alpha-globulin (LTAM-1), ferritin (LTAM-2) and lactoferrin (LTAM-3) were separated by a combination of ion exchange, dye-affinity and molecular sieve chromatography. They were further purified by polyacrylamide gel electrophoresis ...

journal_title：Oncology

authors： Maxim PE,Veltri RW,Sprinkle PM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Clear cell renal cell carcinoma (CCRCC) is a malignant neoplasm frequently associated with an increase in circulating immune complexes (CIC). Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a disease involving the chorioretinal structures of the eye, and it is commonly observe...

journal_title：Oncology

authors： Parmeggiani F,Costagliola C,D'Angelo S,Incorvaia C,Perri P,Sebastiani A

更新日期：2004-01-01 00:00:00

abstract：:67Ga-subtraction scan was found to be useful and a promising new method for the pre-treatment evaluation of the patient with Hodgkin's disease or non-Hodgkin's lymphoma. The scan appeared to be most accurate in the neck, chest, and axillary regions. It appears to offer a means of increasing the accuracy of evaluating ...

journal_title：Oncology

authors： Krolikiewicz H,Maruyama Y,Deland FH,Beihn RM,Hafner T,Utley JF

更新日期：1977-01-01 00:00:00

abstract：:Twenty-seven patients with advanced measurable colorectal carcinoma were treated with a combination protocol consisting of folinic acid (FA) 200 mg/m2 i.v. bolus followed by 5-fluorouracil (5-FU) 550 mg/m2, and cisplatin (CIS) 20 mg/m2 each administered as a 2-hour i.v. infusion. Treatment was given on 4 consecutive d...

journal_title：Oncology

authors： Scheithauer W,Depisch D,Schiessel R,Ludwig H

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The clinical features of hepatocellular carcinoma (HCC) differ in patients with and without cirrhosis. OBJECTIVE:We aimed to investigate the long-term outcomes of noncirrhotic HCC patients after curative resection. METHODS:We retrospectively examined 649 consecutive patients with HCC who underwent curative...

journal_title：Oncology

authors： Lee HW,Choi GH,Kim DY,Park YN,Kim KS,Choi JS,Ahn SH,Han KH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Variations in the incidence of cancer can be influenced by diet and specific lifestyles. In the last years, diet has been evaluated as an important factor in the development of ovarian cancer, even though the results have not been consistent. Dietary factors related to the risk of ovarian cancer in Mexican w...

journal_title：Oncology

authors： Salazar-Martinez E,Lazcano-Ponce EC,Gonzalez Lira-Lira G,Escudero-De los Rios P,Hernandez-Avila M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Postoperative management of patients with pancreatic adenocarcinoma (PA) is controversial. METHODS:The aim of this pilot study was to assess the feasibility of postoperative combination chemotherapy followed by radiotherapy in patients aged 18-70 years with a histological diagnosis of PA, and Karnofsky perf...

journal_title：Oncology

authors： Reni M,Passoni P,Bonetto E,Balzano G,Panucci MG,Zerbi A,Ronzoni M,Staudacher C,Villa E,Di Carlo V

更新日期：2005-01-01 00:00:00

abstract：:Lewis lung carcinoma (3LL), which has been most frequently used for various investigations of cancer, was converted to an ascitic form designated 3LL-SA. Ascites tumor cells showed a mixed population of single cells and about 10% islands which were made up of 2 to about 50 cells. Transplantability was 100%. The biolog...

journal_title：Oncology

authors： Sato T,Takusagawa K,Asoo N,Kumano N,Hasuike M,Konno K

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:Pegylated liposomal doxorubicin (PLD) and capecitabine (CAP) have separately shown significant antitumor activity in a wide range of solid tumors. A phase I study was conducted in order to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of their combination in patients with refr...

journal_title：Oncology

authors： Maltezos E,Amarantidis K,Trichas M,Vasiliadis M,Toromanidou M,Chatzaki E,Karayiannakis A,Tsaroucha A,Romanidis K,Kakolyris S

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Calcitriol, 1alpha,25-dihydroxyvitamin D(3) (1,25-D(3)) has potent antiproliferative effects and potentiates the antitumor activity of many other cytotoxic drugs. 1,25-D(3) plasma pharmacokinetic (PK) parameters associated with antitumor activity in experimental animal models are unknown. The objective of th...

journal_title：Oncology

authors： Muindi JR,Modzelewski RA,Peng Y,Trump DL,Johnson CS

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Identification of high-risk stage II colorectal cancer (CRC) patients, potential candidates for adjuvant chemotherapy, is challenging. Current clinical guidelines rely mainly on histopathological markers with relatively weak prognostic value. This motivates further search for prognostic markers. METHODS:Thi...

journal_title：Oncology

authors： Dimberg J,Andersson RE,Haglund S

更新日期：2020-01-01 00:00:00

abstract：:Novel human estrogen receptor (ER)-beta was identified in cDNA libraries from human testis. ER-beta specifically expresses in testis, ovary, thymus, spleen, osteoblasts and fetus. ER-beta might not conserve the same physiological functions as does ER-alpha. Therefore, the clinical significance of the expression of ER-...

journal_title：Oncology

authors： Fujimoto J,Hirose R,Sakaguchi H,Tamaya T

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to investigate whether the Ile646Val (2073A>G) polymorphism in the kinase-binding domain of A-kinase anchoring protein 10 (AKAP10) is related to the risk of colorectal cancer (CRC), clinicopathological variables and the environmental factors for the development of CRC. METHODS:Ap...

journal_title：Oncology

authors： Wang MJ,Zhou ZG,Wang L,Yu YY,Zhang P,Zhang Y,Cui CF,Yang L,Li Y,Zhou B,Sun XF

更新日期：2009-01-01 00:00:00