The rational use of i.v. hydrochloric acid in the treatment of metabolic alkalosis.

abstract：BACKGROUND:Transitions into and out of the anaesthetised state exhibit resistance to state transitions known as neural inertia. As a consequence, emergence from anaesthesia occurs at a consistently lower anaesthetic concentration than induction. Motivated by stochastic switching between discrete activity patterns obser...

journal_title：British journal of anaesthesia

authors： Proekt A,Hudson AE

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Lower thoracic epidural anaesthesia and analgesia (EDA) has gained increasing importance in perioperative pain therapy. The loss-of-resistance technique used to identify the epidural space is thought to rely on the penetration of the ligamentum flavum. Investigations at the cervical and lumbar regions have d...

journal_title：British journal of anaesthesia

authors： Lirk P,Colvin J,Steger B,Colvin HP,Keller C,Rieder J,Kolbitsch C,Moriggl B

更新日期：2005-06-01 00:00:00

abstract：:We studied 325 patients undergoing elective noncardiac surgery who had preoperative ambulatory ECG monitoring performed for a duration of 5130 h (range 8-24 h; mean 15.8 h). Sixty-four subjects (20%) had one or more episodes of ST segment depression consistent with myocardial ischaemia. Of all preoperative cardiovascu...

journal_title：British journal of anaesthesia

authors： Allman KG,Muir A,Howell SJ,Hemming AE,Sear JW,Foëx P

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Plethysmographic variability index (PVI) is an accurate predictor of fluid responsiveness in mechanically ventilated patients. However, the site of measurement of the plethysmographic waveform impacts its morphology and its respiratory variation. The goal of this study was to investigate the ability of PVI t...

journal_title：British journal of anaesthesia

authors： Desgranges FP,Desebbe O,Ghazouani A,Gilbert K,Keller G,Chiari P,Robin J,Bastien O,Lehot JJ,Cannesson M

更新日期：2011-09-01 00:00:00

abstract：:The rate of gastric emptying in pregnancy was measured indirectly using the rate of paracetamol absorption in four groups of 15 patients: non-pregnant controls, first trimester patients presenting for termination of pregnancy, second trimester patients presenting for prostaglandin termination of pregnancy, and patient...

journal_title：British journal of anaesthesia

authors： Macfie AG,Magides AD,Richmond MN,Reilly CS

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Muscle relaxants facilitate tracheal intubation, but they are often not used for short peripheral surgical procedures. The consequences of this practice on the upper airway are still a matter of controversy. We therefore compared the incidence of post-intubation symptoms in a randomized study comparing patie...

journal_title：British journal of anaesthesia

authors： Combes X,Andriamifidy L,Dufresne E,Suen P,Sauvat S,Scherrer E,Feiss P,Marty J,Duvaldestin P

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Postoperative non-cardiac complication rates are as high as 11-28% after high-risk abdominal procedures. Emerging evidence indicates that postoperative cardiac troponin T elevations are associated with adverse outcome in non-cardiac surgery. The aim of this study was to determine the relationship between pos...

journal_title：British journal of anaesthesia

authors： Noordzij PG,van Geffen O,Dijkstra IM,Boerma D,Meinders AJ,Rettig TC,Eefting FD,van Loon D,van de Garde EM,van Dongen EP

更新日期：2015-06-01 00:00:00

abstract：:A total of 1442 patients who had major gynaecological surgery were recruited into three multicentre studies using a standard general anaesthetic technique in order to assess the efficacy of various doses of orally administered ondansetron in the prevention of postoperative nausea and vomiting. A total of 1257 patients...

journal_title：British journal of anaesthesia

authors： Haigh CG,Kaplan LA,Durham JM,Dupeyron JP,Harmer M,Kenny GN

更新日期：1993-10-01 00:00:00

abstract：:Cancer treatment is associated with significant morbidity and mortality. Surgery is a mainstay of treatment for many tumours, and anaesthetists care for cancer patients on a daily basis. Surgery itself induces a stress response and inhibits the immune system, and cancer surgery is associated with the release of tumour...

journal_title：British journal of anaesthesia

authors： Tedore T

更新日期：2015-12-01 00:00:00

abstract：:We have studied the effects of flow and dobutamine on systemic haemodynamic variables, oxygen delivery (DO2) and oxygen consumption (VO2) in 20 patients during cardiopulmonary bypass (CPB) with mild hypothermia (34 degrees C). In a subgroup of seven patients, we also studied the effects on gastric microcirculatory blo...

journal_title：British journal of anaesthesia

authors： Karzai W,Lötte A,Günnicker M,Vorgrimler-Karzai UM,Priebe HJ

更新日期：1996-01-01 00:00:00

abstract：:We have tested the hypothesis that intradermal testing is a more effective method for determining the drug responsible for anaesthetic anaphylactic reactions than prick testing in 212 consecutive patients, aged more than 10 yr, referred to an anaesthetic allergy clinic over a 4-yr period. The study was a prospective, ...

journal_title：British journal of anaesthesia

authors： Fisher MM,Bowey CJ

更新日期：1997-07-01 00:00:00

abstract：:We have examined the influence of electrical stimulation on caffeine-induced tension generation during contracture testing used to diagnose malignant hyperthermia. The cumulative contracture response to caffeine was compared in pairs of morphologically comparable muscle bundles obtained from the same patient. Only one...

journal_title：British journal of anaesthesia

authors： Heytens L,Martin JJ,Bossaert LL

更新日期：1992-07-01 00:00:00

abstract：:The effects of different premedication (i.m. and i.v.) on the usefulness of midazolam or thiopentone as induction agents for minor surgery was studied in 194 women undergoing either dilatation and curettage or explorative fractionate curettage. Midazolam appeared to produce light sedation which required powerful preme...

journal_title：British journal of anaesthesia

authors： Kanto J,Sjövall S,Vuori A

更新日期：1982-05-01 00:00:00

abstract：:The neuromuscular blocking effect of repeated bolus administration of suxamethonium 1 mg/kg was observed in 10 healthy surgical patients under enflurane-nitrous oxide-oxygen anaesthesia. Tachyphylaxis and slow recovery of the thumb twitch occurred in close dose-relationships with transition of Phase I block to Phase I...

journal_title：British journal of anaesthesia

authors： Lee C,Chen D,Nagel EL,Katz RL

更新日期：1976-02-01 00:00:00

abstract：:The coherent frequency (CF) of the auditory evoked response (AER) is derived using auditory clicks presented at frequencies in the range 5-47 Hz. CF and psychological performance were measured while seven subjects breathed isoflurane in doses increasing from 0% to 0.2%, 0.4% and 0.8% end-tidal concentration and then d...

journal_title：British journal of anaesthesia

authors： Munglani R,Andrade J,Sapsford DJ,Baddeley A,Jones JG

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Evidence-based international expert consensus regarding anaesthetic practice in hip/knee arthroplasty surgery is needed for improved healthcare outcomes. METHODS:The International Consensus on Anaesthesia-Related Outcomes after Surgery group (ICAROS) systematic review, including randomised controlled and ob...

journal_title：British journal of anaesthesia

authors： Memtsoudis SG,Cozowicz C,Bekeris J,Bekere D,Liu J,Soffin EM,Mariano ER,Johnson RL,Hargett MJ,Lee BH,Wendel P,Brouillette M,Go G,Kim SJ,Baaklini L,Wetmore D,Hong G,Goto R,Jivanelli B,Argyra E,Barrington MJ,Borgea

更新日期：2019-09-01 00:00:00

abstract：:The gliding characteristics were evaluated of 10-ml plastic syringes used to identify the extradural space by "loss of resistance" techniques. This was undertaken quantitatively, by measuring the force necessary to depress syringe plungers, and qualitatively, by examining travel characteristics in terms of the force a...

journal_title：British journal of anaesthesia

authors： Bricker SR,Coleman P

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:The relationship between end-tidal sevoflurane concentration, bispectral index (BIS) and the EEG bispectrum in children appears to be age dependent. The aim of this study was to quantify the BIS values at 1 MAC (minimum alveolar concentration) for desflurane and halothane, and explore the relationship with a...

journal_title：British journal of anaesthesia

authors： Tirel O,Wodey E,Harris R,Bansard JY,Ecoffey C,Senhadji L

更新日期：2006-04-01 00:00:00

abstract：:Topical capsaicin formulations are used for pain management. Safety and modest efficacy of low-concentration capsaicin formulations, which require repeated daily self-administration, are supported by meta-analyses of numerous studies. A high-concentration capsaicin 8% patch (Qutenza™) was recently approved in the EU a...

journal_title：British journal of anaesthesia

authors： Anand P,Bley K

更新日期：2011-10-01 00:00:00

abstract：:Arterial oxygenation was measured in patients being ventilated artificially for respiratory failure, initially at the FIO2 that had been selected clinically to achieve PaO2 at least normal, and then at each of two or three progressively increased FIO2 values up to about 0.9. Impairment of oxygen transfer was assessed ...

journal_title：British journal of anaesthesia

authors： Drummond GB,Zhong NS

更新日期：1983-01-01 00:00:00

abstract：:One hundred and forty male rats received a cryoinjury to a segment of the exposed sciatic nerve. A variety of temperatures and freeze patterns was used and the recovery of function was monitored. Where obvious nerve freezing occurred, the cryoinjury caused complete loss of function in the limb. The return of motor act...

journal_title：British journal of anaesthesia

authors： Evans PJ,Lloyd JW,Green CJ

更新日期：1981-11-01 00:00:00

abstract：:We gave either midazolam or propofol for induction of anaesthesia to 140 ASA I or II female patients (18-60 yr). ED50 values were obtained by probit analysis for three clinical end-points: loss of response to command; loss of eyelash reflex; failure to respond to application of an anaesthetic face mask delivering 1% i...

journal_title：British journal of anaesthesia

authors： McClune S,McKay AC,Wright PM,Patterson CC,Clarke RS

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Perioperative studies of patients following hip fracture have large heterogeneity within their reported outcomes. This study aimed to develop a core outcome set for use in perioperative studies comparing the types of anaesthesia for hip fracture surgery. METHODS:The consensus process consisted of a systemat...

journal_title：British journal of anaesthesia

authors： O'Donnell CM,Black N,McCourt KC,McBrien ME,Clarke M,Patterson CC,Blackwood B,McAuley DF,Shields MO

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We investigated the effects of spinal and general anaesthesia and surgical tourniquet on acute pain and early recovery after total knee arthroplasty (TKA). METHODS:Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without...

journal_title：British journal of anaesthesia

authors： Palanne R,Rantasalo M,Vakkuri A,Madanat R,Olkkola KT,Lahtinen K,Reponen E,Linko R,Vahlberg T,Skants N

更新日期：2020-11-01 00:00:00

abstract：:The induction dose requirements of propofol were compared in three age groups in 300 unpremedicated healthy Chinese children: group A, younger than 2 yr (n = 48); group B, 2-5 yr (n = 117); group C, 6-12 yr (n = 135). Patients in each group were allocated randomly to receive one of eight doses of propofol (1.2, 1.4, 1...

journal_title：British journal of anaesthesia

authors： Aun CS,Short SM,Leung DH,Oh TE

更新日期：1992-01-01 00:00:00

abstract：:Animal studies suggest that alpha 2 agonists inhibit the chemoreceptor response to hypoxia. We have examined the effect of oral clonidine on the ventilatory response to sustained, isocapnic hypoxia (SpO2 79.7% (SD 1.1%) for 20 min) in eight male subjects. The hypoxic ventilatory response was measured before and after ...

journal_title：British journal of anaesthesia

authors： Foo IT,Warren PM,Drummond GB

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:We describe a practical method of training anaesthetists in the technique of awake fibreoptic intubation. This is performed on a training course using the delegates as subjects. METHODS:The first 15 subjects underwent cardiovascular monitoring during airway fibreoptic endoscopy performed by other course mem...

journal_title：British journal of anaesthesia

authors： Patil V,Barker GL,Harwood RJ,Woodall NM

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:The efficacy of opioids typically decreases after long-term use owing to the development of tolerance. Glial activation and the upregulation of proinflammatory cytokines are related to the induction of tolerance. We investigated the effect of leukemia inhibitory factor (LIF) on morphine analgesia and toleran...

journal_title：British journal of anaesthesia

authors： Tu HJ,Kang KH,Ho SY,Liou HC,Liou HH,Lin CP,Fu WM

更新日期：2016-10-01 00:00:00

abstract：:We have examined the correlation between the evoked electromyographic response in the first dorsal interosseous muscle of the hand, temperature and forearm position in 40 female patients after enflurane anaesthesia with spontaneous breathing. In 20 patients the supinated forearm with the wrist extended was immobilized...

journal_title：British journal of anaesthesia

authors： Smith DC,Booth JV

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:The objective of this study was to test whether non-invasive assessment of respiratory stroke volume variation (ΔrespSV) by oesophageal Doppler monitoring (ODM) can predict fluid responsiveness during surgery in a mixed population. The predictive value of ΔrespSV was evaluated using a grey zone approach. ME...

journal_title：British journal of anaesthesia

authors： Guinot PG,de Broca B,Abou Arab O,Diouf M,Badoux L,Bernard E,Lorne E,Dupont H

更新日期：2013-01-01 00:00:00