Effect of different kinds of premedication on the induction properties of midazolam.

abstract：:Cancer treatment is associated with significant morbidity and mortality. Surgery is a mainstay of treatment for many tumours, and anaesthetists care for cancer patients on a daily basis. Surgery itself induces a stress response and inhibits the immune system, and cancer surgery is associated with the release of tumour...

journal_title：British journal of anaesthesia

authors： Tedore T

更新日期：2015-12-01 00:00:00

abstract：:We have investigated the effect of a bolus injection of atracurium 0.6 mg kg-1 on the cardiovascular system in 16 patients undergoing aortocoronary bypass surgery. H1- and H2-receptor antagonists were administered to eight patients before the neuromuscular blocker. A standard anaesthetic was used comprising fentanyl, ...

journal_title：British journal of anaesthesia

authors： Adt M,Baumert JH,Reimann HJ

更新日期：1992-02-01 00:00:00

abstract：:The extent of air contamination by halothane in an operating session was correlated with the number of patients, the total usage of halothane, refilling a vaporizer and the number of hyperventilating patients per session. Trichloroethylene content of theatre air correlated only with total usage and refilling a vaporiz...

journal_title：British journal of anaesthesia

authors： Thompson JM,Barratt RS,Hutton P,Robinson JS,Belcher R,Stephen WI

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) pressure-volume (PV) loops were used to compare the functional effects that accompany the cardioprotection seen with desflurane, sevoflurane, and propofol in a rabbit preparation of coronary ischaemia-reperfusion (IR). METHODS:Male New Zealand White rabbits (n=48) were anaesthetized wi...

journal_title：British journal of anaesthesia

authors： Andrews DT,Royse AG,Royse CF

更新日期：2009-11-01 00:00:00

abstract：:A randomized, double-blind study of 40 women was performed to compare patient controlled anaesthesia (PCA) morphine requirements after spinal anaesthesia for elective Caesarean section. The women received 0.2 mg of either morphine or diamorphine mixed with 0.5% bupivacaine in 8% dextrose. There were no significant dif...

journal_title：British journal of anaesthesia

authors： Husaini SW,Russell IF

更新日期：1998-08-01 00:00:00

abstract：:Bioactive substances in fresh frozen plasma (FFP) are considered to be related to adverse reactions after transfusion, particularly in septic or traumatized patients. Therefore, we analysed the concentration of various bioactive substances (histamine, eosinophil cationic protein, eosinophil protein X, myeloperoxidase ...

journal_title：British journal of anaesthesia

authors： Nielsen HJ,Reimert C,Pedersen AN,Dybkjoer E,Brünner N,Alsbjørn B,Skov PS

更新日期：1997-05-01 00:00:00

abstract：:A new design of tracheal tube cuff was compared with two types of high-volume, low-pressure (HVLP) cuffed tracheal tube for leakage of fluid from the subglottic space into the trachea. Spontaneous and positive-pressure ventilation were simulated using a mechanical lung, an intubated model trachea and a ventilator. Exc...

journal_title：British journal of anaesthesia

authors： Young PJ,Ridley SA,Downward G

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Magnesium is a calcium and an NMDA-receptor antagonist and can modify important mechanisms of nociception. We evaluated the co-analgesic effect of magnesium in the postoperative setting after on-pump cardiac surgery. METHODS:Forty patients randomly received either magnesium gluconate as an i.v. bolus of 0.2...

journal_title：British journal of anaesthesia

authors： Steinlechner B,Dworschak M,Birkenberg B,Grubhofer G,Weigl M,Schiferer A,Lang T,Rajek A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Tracheal tube tip and cuff positions of different cuffed paediatric tracheal tube brands in the trachea can vary with design. METHODS:Data from three clinical studies with measured tracheal lengths were pooled in a database including 422 children aged from birth to 16 yr. Dimensional data of seven cuffed pa...

journal_title：British journal of anaesthesia

authors： Kemper M,Imach S,Buehler PK,Thomas J,Dave M,Weiss M

更新日期：2018-08-01 00:00:00

abstract：:The physical and pharmacological properties of the structural isomers isoflurane and enflurane differ from each other and from those of other potent inhaled anaesthetics. The minimum alveolar concentration (MAC) for isoflurane (1.15%) is one-and-one-half times that for halothane (0.75%) and two-thirds that for enflura...

journal_title：British journal of anaesthesia

authors： Eger EI 2nd

更新日期：1984-01-01 00:00:00

abstract：:In order to clarify the relative contribution of hepatic metabolism to the short term disposition of methohexitone, we have measured hepatic blood flow during induction of anaesthesia with a 1.5-mg kg-1 i.v. bolus dose of methohexitone. Median hepatic clearance was 1.01 litre min-1 and hepatic extraction 87%. As a con...

journal_title：British journal of anaesthesia

authors： Lange H,Stephan H,Brand C,Zielmann S,Sonntag H

更新日期：1992-11-01 00:00:00

abstract：:We have studied 16 healthy volunteers whose lungs were preoxygenated six times each in order to assess the amount of room air entrained during tidal volume preoxygenation if a good seal is not maintained between the face mask and the face. With a fresh gas flow of 10 litre min-1, we found that using gravity alone to h...

journal_title：British journal of anaesthesia

authors： McGowan P,Skinner A

更新日期：1995-12-01 00:00:00

abstract：:Recent research has shown that high-frequency, gamma-band electroencephalographic (EEG) oscillations (40-60 Hz) may be an important marker of the conscious state. We compared the ability of the bispectral index (BIS) to distinguish the awake and anaesthetized states during the induction of general anaesthesia with: (i...

journal_title：British journal of anaesthesia

authors： Sleigh JW,Steyn-Ross DA,Steyn-Ross ML,Williams ML,Smith P

更新日期：2001-01-01 00:00:00

abstract：:We have investigated 60 patients in a prospective double-blind, placebo-controlled study to assess the efficacy of EMLA (Eutectic Mixture of Local Anaesthetics) cream to provide analgesia during extracorporeal shock wave lithotripsy (ESWL) with a second generation lithotriptor. Before operation, EMLA or placebo cream ...

journal_title：British journal of anaesthesia

authors： McDonald PF,Berry AM

更新日期：1992-10-01 00:00:00

abstract：:The analgesic effects and bioavailability of a slow-release preparation of morphine (Duromorph) were studied in 12 patients with acute postoperative pain. Duromorph produced significant analgesia within 1-2 h of administration i.m., and there was a progressive decrease in the mean pain score for at least 8 h. None of ...

journal_title：British journal of anaesthesia

authors： Charway CL,Calvey TN,Williams NE,Murray GR

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Signalling of several G-protein-coupled receptors of the Gq/11 family is time-dependently inhibited by local anaesthetics (LAs). Since LA-induced modulation of muscarinic m1 and m3 receptor function may explain their beneficial effects in clinical practice, such as decreased postoperative cognitive dysfuncti...

journal_title：British journal of anaesthesia

authors： Picardi S,Stevens MF,Hahnenkamp K,Durieux ME,Lirk P,Hollmann MW

更新日期：2014-02-01 00:00:00

abstract：Background:In addition to general anaesthetic effects, sevoflurane can also induce hyperactive behaviours during induction and recovery, which may contribute to neurotoxicity; however, the mechanism of such effects is unclear. Volatile anaesthetics including isoflurane have been found to activate the kainate (GluK2) re...

journal_title：British journal of anaesthesia

authors： Liang P,Li F,Liu J,Liao D,Huang H,Zhou C

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Fibrinolysis contributes to coagulopathy after major trauma and surgery. We hypothesized that progressive haemodilution is responsible, at least in part, for increased fibrinolytic tendency of blood clot. METHODS:The study was performed in two parts. First, whole blood (WB) samples collected from six health...

journal_title：British journal of anaesthesia

authors： Bolliger D,Szlam F,Levy JH,Molinaro RJ,Tanaka KA

更新日期：2010-03-01 00:00:00

abstract：:We have compared mivacurium and succinylcholine in 27 paediatric patients with mild (Child's A) to moderate (Child's B) liver disease undergoing oesophagogastroduodenoscopy (OGD) and injection of oesophageal varices, with 10 healthy children receiving mivacurium for ENT procedures. With mivacurium 0.2 mg kg-1, the sev...

journal_title：British journal of anaesthesia

authors： Green DW,Fisher M,Sockalingham I

更新日期：1998-09-01 00:00:00

abstract：:The aim of this study was to find, using modern techniques, any histological differences in muscle biopsies between malignant hyperthermia (MH) susceptible (MHS), MH equivocal (MHE) and MH negative (MHN) patients. On the basis of the European MH contracture test carried out in 83 patients, 23 were shown to be MHS, nin...

journal_title：British journal of anaesthesia

authors： Mezin P,Payen JF,Bosson JL,Brambilla E,Stieglitz P

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Paradoxical excitement response during sedation consists of loss of affective control and abnormal movements. Chronic alcohol abuse has been proposed as a predisposing factor despite lack of supporting evidence. Because alcohol and propofol have a common site of action, we postulated that paradoxical excitem...

journal_title：British journal of anaesthesia

authors： Jeong S,Lee HG,Kim WM,Jeong CW,Lee SH,Yoon MH,Choi JI

更新日期：2011-12-01 00:00:00

abstract：:We have examined the role of benzodiazepine receptors in nitrous oxide-induced neuronal depression in rats. The changes in neuronal excitability induced by nitrous oxide and the benzodiazepine inverse agonist, Ro15-4513, were monitored by measurement of visual evoked potentials (VEP). Administration of Ro15-4513 10 mg...

journal_title：British journal of anaesthesia

authors： Dzoljic M,Erdmann W,Dzoljic MR

更新日期：1996-10-01 00:00:00

abstract：:An animal model was established to study the toxic effects of hyperoxia and the consequent changes in intracellular antioxidant status. Superoxide dismutase, catalase and glutathione peroxidase activities were measured in erythrocytes, liver and lung, in addition to cellular glutathione concentrations and its associat...

journal_title：British journal of anaesthesia

authors： Webster NR,Toothill C,Cowen PN

更新日期：1987-06-01 00:00:00

abstract：:Advances in cannabis research have paralleled developments in opioid pharmacology whereby a psychoactive plant extract has elucidated novel endogenous signalling systems with therapeutic significance. Cannabinoids (CBs) are chemical compounds derived from cannabis. The major psychotropic CB delta-9-tetrahydrocannabino...

journal_title：British journal of anaesthesia

authors： Hosking RD,Zajicek JP

更新日期：2008-07-01 00:00:00

abstract：:The neuromuscular blocking effects of equipotent doses of the three putative metabolites of vecuronium (3-hydroxy vecuronium, 17-hydroxy vecuronium and 3,17-dihydroxy vecuronium) were compared with those of an equipotent dose of vecuronium. Results obtained with the liver excluded from the circulation and after intrap...

journal_title：British journal of anaesthesia

authors： Bencini AF,Houwertjes MC,Agoston S

更新日期：1985-08-01 00:00:00

abstract：:Continuous intercostal nerve blockade was used to provide analgesia after cholecystectomy. The blockade was maintained by the insertion of a single extradural catheter into an appropriate intercostal space and by "topping-up" with local anaesthetic on demand. Of the patients studied, 92%, and 76%, required no addition...

journal_title：British journal of anaesthesia

authors： Murphy DF

更新日期：1983-06-01 00:00:00

abstract：:Plasma concentrations of pancuronium were measured using a fluorimetric method in six patients with normal renal function and seven patients in chronic renal failure. A tow-compartment open model was used in the pharmacokinetic analysis of the data. With this model, the clearance of pancuronium was found to be reduce...

journal_title：British journal of anaesthesia

authors： McLeod K,Watson MJ,Rawlins MD

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Robotic-assisted laparoscopic radical prostatectomy (RALRP) is gaining popularity as a less traumatic and minimally invasive alternative to open radical retropubic prostatectomy (RRP). The aim of this study was to evaluate the incidence and grade of venous gas embolism (VGE) during RALRP compared with those ...

journal_title：British journal of anaesthesia

authors： Hong JY,Kim JY,Choi YD,Rha KH,Yoon SJ,Kil HK

更新日期：2010-12-01 00:00:00

abstract：:A simple mathematical model of the chest wall was constructed so that during tidal breathing the relative volume contributions of the rib cage and abdomen/diaphragm could be measured in man, using four mercury-in-rubber strain gauges around the trunk. From the dimensions of the trunk and the change in circumference de...

journal_title：British journal of anaesthesia

authors： Faithfull D,Jones JG,Jordan C

更新日期：1979-05-01 00:00:00

abstract：:We studied the size 4 laryngeal mask airway (LMA) to test the hypothesis that oropharyngeal leak pressure and fibreoptic position improves with increasing cuff volume. After LMA insertion, 50 anaesthetized adult patients had the cuff inflated in 5-ml increments to 40 ml. Oropharyngeal leak pressure was optimal at 15 m...

journal_title：British journal of anaesthesia

authors： Keller C,Pühringer F,Brimacombe JR

更新日期：1998-08-01 00:00:00