Functional comparison of anaesthetic agents during myocardial ischaemia-reperfusion using pressure-volume loops.

abstract：:Sickle cell disease is a congenital haemoglobinopathy with a high incidence of perioperative complications. Traditional anaesthetic management, based largely on extrapolation from biochemical models, has emphasized avoidance of red cell sickling to prevent exacerbations of the disease. This historical review outlines ...

journal_title：British journal of anaesthesia

authors： Firth PG

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:High-dose glucocorticoid may reduce postsurgical pain and improve recovery. We hypothesized that 125 mg methylprednisolone (MP) would reduce time to meet functional discharge criteria after total hip arthroplasty (THA). METHODS:Forty-eight patients undergoing unilateral THA under spinal anaesthesia were con...

journal_title：British journal of anaesthesia

authors： Lunn TH,Andersen LØ,Kristensen BB,Husted H,Gaarn-Larsen L,Bandholm T,Ladelund S,Kehlet H

更新日期：2013-01-01 00:00:00

abstract：:We tested the hypothesis that the solvent for etomidate was a factor in the incidence of pain and other side effects after injection, and that these were associated with histamine release. Nine of 10 volunteers who received etomidate in a propylene glycol formulation reported moderate to severe pain on injection; only...

journal_title：British journal of anaesthesia

authors： Doenicke AW,Roizen MF,Hoernecke R,Lorenz W,Ostwald P

更新日期：1999-09-01 00:00:00

abstract：:We evaluated prospectively the use of Gram staining of protected pulmonary specimens to allow the early diagnosis of ventilator-associated pneumonia (VAP), compared with the use of 60 bronchoscopic protected specimen brushes (PSB) and 126 blinded plugged telescopic catheters (PTC) obtained from 134 patients. Gram stai...

journal_title：British journal of anaesthesia

authors： Mimoz O,Karim A,Mazoit JX,Edouard A,Leprince S,Nordmann P

更新日期：2000-11-01 00:00:00

abstract：:During resection of a Wilms' tumour in a 10-year-old girl, sudden bradycardia, hypotension and cyanosis developed, leading to cardiac arrest. It was thought that part of the tumour had caused a pulmonary embolus. After prompt resuscitation, cardiopulmonary bypass surgery was started within 20 min. At operation the lef...

journal_title：British journal of anaesthesia

authors： Akyön MG,Arslan G

更新日期：1981-08-01 00:00:00

abstract：:The relationship between maternal FIO2 and umbilical venous PO2, PCO2, pH and neonatal Apgar and TSR (time to sustained respiration) scores was studied in 35 patients undergoing Caesarean section under general anaesthesia. Patients were allocated randomly to breathe an FIO2 of either 0.5 or 0.33. Umbilical venous bloo...

journal_title：British journal of anaesthesia

authors： Lawes EG,Newman B,Campbell MJ,Irwin M,Dolenska S,Thomas TA

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Ischaemia is one of the causative mechanisms of peripheral nerve injury, a documented complication of regional anaesthesia. Local anaesthetics per se and/or vasopressor adjuvants may account for changes in peripheral nerve blood flow. The aim of this study was to test the effects of levobupivacaine and ropiv...

journal_title：British journal of anaesthesia

authors： Bouaziz H,Iohom G,Estèbe JP,Campana WM,Myers RR

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Clinicians frequently warn patients of discomfort before potentially painful procedures, despite the lack of evidence that such communications are helpful. We aimed to compare two communications (one with, and the other without, a warning of a 'sting') immediately before i.v. cannulation in order to measure ...

journal_title：British journal of anaesthesia

authors： Dutt-Gupta J,Bown T,Cyna AM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Overt stroke after non-cardiac surgery has a substantial impact on the duration and quality of life. Covert stroke in the non-surgical setting is much more common than overt stroke and is associated with an increased risk of cognitive decline and dementia. Little is known about covert stroke after non-cardia...

journal_title：British journal of anaesthesia

authors： Mrkobrada M,Hill MD,Chan MT,Sigamani A,Cowan D,Kurz A,Sessler DI,Jacka M,Graham M,Dasgupta M,Dunlop V,Emery DJ,Gulka I,Guyatt G,Heels-Ansdell D,Murkin J,Pettit S,Sahlas DJ,Sharma M,Sharma M,Srinathan S,St John P

更新日期：2016-08-01 00:00:00

abstract：:A double-blind trial was undertaken to compare the effects of trimeprazine tartrate (2 mg kg-1 or 4 mg kg-1) plus atropine 0.03 mg kg-1 for oral premedication of 192 children undergoing tonsillectomy. Demeanour before operation, side-effects after operation, recovery times and fluid balance were studied. Behaviour in ...

journal_title：British journal of anaesthesia

authors： Bramwell RG,Manford ML

更新日期：1981-08-01 00:00:00

abstract：Background:In addition to general anaesthetic effects, sevoflurane can also induce hyperactive behaviours during induction and recovery, which may contribute to neurotoxicity; however, the mechanism of such effects is unclear. Volatile anaesthetics including isoflurane have been found to activate the kainate (GluK2) re...

journal_title：British journal of anaesthesia

authors： Liang P,Li F,Liu J,Liao D,Huang H,Zhou C

更新日期：2017-11-01 00:00:00

abstract：:As constant hypoxaemia itself may trigger development of apnoea and periodic breathing, we have studied the effect of oxygen therapy on the occurrence of late postoperative episodic hypoxaemia. Thirty-five patients without cardiopulmonary disease and undergoing elective total hip replacement were monitored with a puls...

journal_title：British journal of anaesthesia

authors： Rosenberg J,Pedersen MH,Gebuhr P,Kehlet H

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The development of hydroxyethyl starches (HES) with low impact on blood coagulation but higher volume effect compared with the currently used HES solutions is of clinical interest. We hypothesized that high molecular weight, low-substituted HES might possess these properties. METHODS:Thirty pigs were infuse...

journal_title：British journal of anaesthesia

authors： Madjdpour C,Dettori N,Frascarolo P,Burki M,Boll M,Fisch A,Bombeli T,Spahn DR

更新日期：2005-05-01 00:00:00

abstract：:The insufflation of oxygen at 1 litre kg-1 min-1 via two endobronchial catheters (called continuous flow ventilation (CFV)) maintained a normal PaCO2 and a constant PaO2 in anaesthetized paralysed dogs and in five out of seven cats. In two cats with a high carbon dioxide production, CFV failed to maintain carbon dioxi...

journal_title：British journal of anaesthesia

authors： Perl A,Whitwam JG,Chakrabarti MK,Taylor VM

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:The effects of thoracic epidural anaesthesia (TEA) on gastric mucosal microvascular haemoglobin oxygenation (microHbO(2)) are unclear. At the splanchnic level, reduction of sympathetic tone may promote vasodilation and increase microHbO(2). However, these splanchnic effects are counteracted by systemic effec...

journal_title：British journal of anaesthesia

authors： Schwarte LA,Picker O,Höhne C,Fournell A,Scheeren TW

更新日期：2004-10-01 00:00:00

abstract：:The extent of air contamination by halothane in an operating session was correlated with the number of patients, the total usage of halothane, refilling a vaporizer and the number of hyperventilating patients per session. Trichloroethylene content of theatre air correlated only with total usage and refilling a vaporiz...

journal_title：British journal of anaesthesia

authors： Thompson JM,Barratt RS,Hutton P,Robinson JS,Belcher R,Stephen WI

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Tracheal tube tip and cuff positions of different cuffed paediatric tracheal tube brands in the trachea can vary with design. METHODS:Data from three clinical studies with measured tracheal lengths were pooled in a database including 422 children aged from birth to 16 yr. Dimensional data of seven cuffed pa...

journal_title：British journal of anaesthesia

authors： Kemper M,Imach S,Buehler PK,Thomas J,Dave M,Weiss M

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Early postoperative negative behaviour in preschool children after general anaesthesia is a common problem. The distinction between emergence delirium (ED) and pain is difficult, but management differs between the two. The aim of the current analysis was to identify individual observational variables that ca...

journal_title：British journal of anaesthesia

authors： Somaini M,Engelhardt T,Fumagalli R,Ingelmo PM

更新日期：2016-03-01 00:00:00

abstract：:We report a case of improved cardiopulmonary exercise (CPX) test outcomes measured 48 h after initial CPX testing and immediately after alterations were made to the settings of a dual chamber, dual sensing pacemaker with exercise detection. The changes allowed successful abdominal surgery to be completed. ...

journal_title：British journal of anaesthesia

authors： Bolsin S,Colson M,Ridley D,Ward C

更新日期：2014-06-01 00:00:00

abstract：:We have examined the correlation between the evoked electromyographic response in the first dorsal interosseous muscle of the hand, temperature and forearm position in 40 female patients after enflurane anaesthesia with spontaneous breathing. In 20 patients the supinated forearm with the wrist extended was immobilized...

journal_title：British journal of anaesthesia

authors： Smith DC,Booth JV

更新日期：1994-04-01 00:00:00

abstract：:We have studied the effects of mivacurium after induction of anaesthesia with alfentanil-propofol in healthy adult oral surgical patients. Anaesthesia was maintained with nitrous oxide and 0.75% (end-tidal) enflurane in oxygen after nasotracheal intubation. Recordings were made of the rectified compound adductor polli...

journal_title：British journal of anaesthesia

authors： Goldhill DR,Whitehead JP,Emmott RS,Griffith AP,Bracey BJ,Flynn PJ

更新日期：1991-09-01 00:00:00

abstract：:This paper describes the use of solenoid valves for the production of binary gas mixtures. The system is controlled by a microprocessor and is capable of delivering accurate flows and concentrations of gases over the ranges commonly used in anaesthesia. Since the flow produced by the valves is pulsatile, a system for ...

journal_title：British journal of anaesthesia

authors： Palayiwa E,Hahn CE,Sugg BR,Lindsay-Scott D,Tyrrell PJ

更新日期：1986-09-01 00:00:00

abstract：:A patient with a foreign body penetrating the neck and chest was found to have physical signs which were consistent with serious tracheal injury and included a large movement of air through the lower part of the neck. The subsequent management of the patient and the difficult problem of securing an airway are describe...

journal_title：British journal of anaesthesia

authors： Brierley JK,Oates J,Bogod DG

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The relationship between end-tidal sevoflurane concentration, bispectral index (BIS) and the EEG bispectrum in children appears to be age dependent. The aim of this study was to quantify the BIS values at 1 MAC (minimum alveolar concentration) for desflurane and halothane, and explore the relationship with a...

journal_title：British journal of anaesthesia

authors： Tirel O,Wodey E,Harris R,Bansard JY,Ecoffey C,Senhadji L

更新日期：2006-04-01 00:00:00

abstract：:Animal studies suggest that alpha 2 agonists inhibit the chemoreceptor response to hypoxia. We have examined the effect of oral clonidine on the ventilatory response to sustained, isocapnic hypoxia (SpO2 79.7% (SD 1.1%) for 20 min) in eight male subjects. The hypoxic ventilatory response was measured before and after ...

journal_title：British journal of anaesthesia

authors： Foo IT,Warren PM,Drummond GB

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Arterial catheterization is painful and is associated with patient stress and anxiety. Analgesia is usually provided by subcutaneous injection of local anaesthetic. An alternative is topical anaesthesia, such as Rapydan which is a novel topical anaesthetic patch containing 70 mg each of lidocaine and tetraca...

journal_title：British journal of anaesthesia

authors： Ruetzler K,Sima B,Mayer L,Golescu A,Dunkler D,Jaeger W,Hoeferl M,You J,Sessler DI,Grubhofer G,Hutschala D

更新日期：2012-11-01 00:00:00

abstract：:We describe an obstetric patient who presented for removal of a retained placenta. After insertion of the spinal anaesthetic, she developed a severe headache, and a subarachnoid haemorrhage was diagnosed. We discuss the differential diagnosis of the headache, the occurrence of intracranial haemorrhages after dural pun...

journal_title：British journal of anaesthesia

authors： Eggert SM,Eggers KA

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Myocardial potassium channels are complexes formed by different subunits. The subunit composition may influence the cardiotoxic action of local anaesthetics. The effects of amide local anaesthetics on HERG channels co-expressed with the putative subunit MiRP1 have not been established. It is also unclear if ...

journal_title：British journal of anaesthesia

authors： Friederich P,Solth A,Schillemeit S,Isbrandt D

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:This study focuses on a recently developed robotic nerve block system and its impact on learning regional anaesthesia skills. We compared success rates, learning curves, performance times, and inter-subject performance variability of robot-assisted vs manual ultrasound (US)-guided nerve block needle guidance...

journal_title：British journal of anaesthesia

authors： Morse J,Terrasini N,Wehbe M,Philippona C,Zaouter C,Cyr S,Hemmerling TM

更新日期：2014-06-01 00:00:00

abstract：:Thirty patients took part in a double-blind trial to compare morphine 10 mg i.m. with morphine 5 mg into the extradural space for pain relief following Caesarean section. With the extradural route the mean time to first analgesia was 7.95 h compared with 4.75 h for the i.m. route. The mean number of further doses of d...

journal_title：British journal of anaesthesia

authors： Chambers WA,Mowbray A,Wilson J

更新日期：1983-12-01 00:00:00