Solvent for etomidate may cause pain and adverse effects.

abstract：:The effects of bolus doses of phenoperidine 1-2 mg i.v. either alone, or combined with pancuronium 2-4 mg, were investigated in seven patients in traumatic coma. Phenoperidine alone significantly reduced mean arterial pressure (MAP) by a mean (+/- SEM) of 13.2 (+/- 2.8) mm Hg. Overall there was no significant change i...

journal_title：British journal of anaesthesia

authors： Bingham RM,Hinds CJ

更新日期：1987-05-01 00:00:00

abstract：:Perioperative risk of death after general surgery is quoted as overall less than 1%. However, each individual's risk varies widely according to many identified factors with some having a significantly increased risk of a worse outcome. The observation that manipulating and targeting certain physiological parameters in...

journal_title：British journal of anaesthesia

authors： Tote SP,Grounds RM

更新日期：2006-07-01 00:00:00

abstract：:This is the report of a 55-yr-old female who developed severe myotonia and dystonia after general anaesthesia. Before starting on gabapentin therapy for a neuropathic pain condition, she had undergone numerous uneventful general anaesthetics. Since receiving treatment with gabapentin, she has experienced severe moveme...

journal_title：British journal of anaesthesia

authors： Allford MA

更新日期：2007-08-01 00:00:00

abstract：:Dose-response relationships for the antagonism of intermediate-acting neuromuscular blocking agents have not been evaluated previously in children. We have examined the dose-response relationships for neostigmine antagonism of 90% rocuronium-induced neuromuscular block in children and adults, during nitrous oxide-1 MA...

journal_title：British journal of anaesthesia

authors： Abdulatif M,Mowafi H,al-Ghamdi A,el-Sanabary M

更新日期：1996-12-01 00:00:00

abstract：:Artery-to-muscle (A-M) onset time for five neuromuscular blocking agents was studied in 50 female patients under light endotracheal anaesthesia. Circulation to the right arm was occluded by a tourniquet and released 1 min after the injection i.v. into the left arm of a myoneural blocking drug. Muscle twitches were rec...

journal_title：British journal of anaesthesia

authors： Minsaas B,Stovner J

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:The Bispectral Index (BIS) is a proprietary index of anaesthesia depth, which is correlated with the level of consciousness and probability of intraoperative recall. The present study investigates the use of a neural network technique to obtain a non-proprietary index of the depth of anaesthesia from the pro...

journal_title：British journal of anaesthesia

authors： Ortolani O,Conti A,Di Filippo A,Adembri C,Moraldi E,Evangelisti A,Maggini M,Roberts SJ

更新日期：2002-05-01 00:00:00

abstract：:We calculated oxygen consumption by the reverse Fick principle (cVO2) using cardiac output measured with a new technique of continuous thermal dilution and compared these values with measurements made at the same time using a gas exchange method (mVO2). We studied nine patients in a stable condition after cardiac surg...

journal_title：British journal of anaesthesia

authors： Bizouarn P,Blanloeil Y,Pinaud M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:We used an automated bispectral index (BIS)-guided dual-loop controller to determine propofol and remifentanil requirements during general anaesthesia in obese and lean surgical patients. METHODS:Obese patients, BMI>35 kg m(-2), and lean patients (<25 kg m(-2)) having laparoscopic procedures were prospectiv...

journal_title：British journal of anaesthesia

authors： Liu N,Lory C,Assenzo V,Cocard V,Chazot T,Le Guen M,Sessler DI,Journois D,Fischler M

更新日期：2015-04-01 00:00:00

abstract：:We have investigated the effect of volatile anaesthetics on protein synthesis and secretion in Hartley male guinea pig liver slices. The slices (250-300 microns thick) were incubated in sealed roller vials containing Krebs-Henseleit buffer at 37 degrees C under 95% oxygen. Volatile anaesthetics were vaporized in the v...

journal_title：British journal of anaesthesia

authors： Ghantous HN,Fernando JL,Keith RL,Gandolfi AJ,Brendel K

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:In regional anaesthesia, there is a risk of direct nerve injury. The purpose of this study was to determine whether the diameter of the applied needle is associated with the magnitude of nerve injury after needle nerve perforation. METHODS:In five anaesthetized pigs, the brachial plexus were exposed bilater...

journal_title：British journal of anaesthesia

authors： Steinfeldt T,Nimphius W,Werner T,Vassiliou T,Kill C,Karakas E,Wulf H,Graf J

更新日期：2010-02-01 00:00:00

abstract：:A possible means of rapid cooling in the emergency treatment of malignant hyperpyrexia, peritoneal dialysis using a cold dialysate, is described. Experimental observations in a young man on a regular peritoneal dialysis regime showed that significant heat extraction can be obtained when either a cool (20 degrees C) or...

journal_title：British journal of anaesthesia

authors： Gjessing J,Barsa J,Tomlin PJ

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:A recent study showed that the noble gas helium induces early myocardial preconditioning. Cyclooxygenase-2 (COX-2) has been shown to be an important mediator in the signal transduction of late preconditioning. In the present study, we investigated whether helium induces late preconditioning in a concentratio...

journal_title：British journal of anaesthesia

authors： Huhn R,Heinen A,Weber NC,Hieber S,Hollmann MW,Schlack W,Preckel B

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:There is limited clinical experience with xenon in a large number of patients. We present intra- and postoperative haemodynamic and recovery data comparing xenon and total intravenous anaesthesia with propofol. METHODS:A total of 160 patients aged 18-60 years (ASA I and II) undergoing elective surgery took ...

journal_title：British journal of anaesthesia

authors： Coburn M,Kunitz O,Baumert JH,Hecker K,Haaf S,Zühlsdorff A,Beeker T,Rossaint R

更新日期：2005-02-01 00:00:00

abstract：:A 4-year-old girl developed severe hepatitis following the fourth administration of halothane in a period of 5 months. She was shown to have a circulating antibody which acted specifically against rabbit hepatocyte previously sensitized to halothane. The patient made a full recovery from the hepatitis, but 5 months la...

journal_title：British journal of anaesthesia

authors： Lewis RB,Blair M

更新日期：1982-03-01 00:00:00

abstract：:Intraoperative awareness, with or without recall, continues to be a topic of clinical significance and neurobiological interest. In this article, we review evidence pertaining to the incidence, sequelae, and prevention of intraoperative awareness. We also assess which aspects of the complication are well understood (i...

journal_title：British journal of anaesthesia

authors： Mashour GA,Avidan MS

更新日期：2015-07-01 00:00:00

abstract：:The coherent frequency (CF) of the auditory evoked response (AER) is derived using auditory clicks presented at frequencies in the range 5-47 Hz. CF and psychological performance were measured while seven subjects breathed isoflurane in doses increasing from 0% to 0.2%, 0.4% and 0.8% end-tidal concentration and then d...

journal_title：British journal of anaesthesia

authors： Munglani R,Andrade J,Sapsford DJ,Baddeley A,Jones JG

更新日期：1993-11-01 00:00:00

abstract：:Gastric (GP) and lower oesophageal sphincter pressures (LOSP) were measured in non-pregnant female volunteers (group I) and pregnant women with (group III) or without (group II) heartburn. Patients in early pregnancy had greater gastric pressures than group I. Mean barrier pressure (LOSP-GP) was significantly decrease...

journal_title：British journal of anaesthesia

authors： Brock-Utne JG,Dow TG,Dimopoulos GE,Welman S,Downing JW,Moshal MG

更新日期：1981-04-01 00:00:00

abstract：:Cryoprecipitate, originally developed as a therapy for patients with antihaemophilic factor deficiency, or haemophilia A, has been in use for almost 50 yr. However, cryoprecipitate is no longer administered according to its original purpose, and is now most commonly used to replenish fibrinogen levels in patients with...

journal_title：British journal of anaesthesia

authors： Nascimento B,Goodnough LT,Levy JH

更新日期：2014-12-01 00:00:00

abstract：:In a prospective, randomized, double-blind clinical study, we have studied 100 children, aged 2-12 yr, to compare halothane and sevoflurane in outpatient dental anaesthesia. All patients were unpremedicated and received inhalation induction using nitrous oxide in oxygen supplemented with either halothane (maximum insp...

journal_title：British journal of anaesthesia

authors： Paris ST,Cafferkey M,Tarling M,Hancock P,Yate PM,Flynn PJ

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:A pulmonary hypertensive crisis (PHC) can be a life-threatening condition. We established a PHC model by exposing rats with monocrotaline (MCT)-induced pulmonary hypertension to acute hypoxia, and investigated the effects of vasopressin, phenylephrine, and norepinephrine on the PHC. METHODS:Four weeks after...

journal_title：British journal of anaesthesia

authors： Sugawara Y,Mizuno Y,Oku S,Goto T

更新日期：2019-04-01 00:00:00

abstract：:Hypertensive patients were monitored for myocardial ischaemia during anaesthesia and surgery with the V5 lead of a standard electrocardiograph. Myocardial ischaemia was detected in 11 of 39 untreated hypertensive patients and in four of seven receiving therapy with a diuretic, but in none of 44 receiving atenolol. Fou...

journal_title：British journal of anaesthesia

authors： Stone JG,Foëx P,Sear JW,Johnson LL,Khambatta HJ,Triner L

更新日期：1988-12-01 00:00:00

abstract：:Effects of ageing were studied on the neural blockade and the pharmacokinetics after subarachnoid administration of 0.5% bupivacaine 3 ml in 8% glucose in two groups of 15 male patients, between 20 and 55 yr and older than 55 yr, respectively. The blockade was performed with the patient in the sitting position. Two mi...

journal_title：British journal of anaesthesia

authors： Veering BT,Burm AG,Spierdijk J

更新日期：1988-02-01 00:00:00

abstract：:Arterial blood and expired gas samples were taken from 20 patients before operation and on the first day after upper abdominal surgery. After operation the patients were studied breathing air and also breathing 35% oxygen from a venturi-type mask. Preoperative Pao2 with age was exaggerated by operation. Pao2 after ope...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1975-04-01 00:00:00

abstract：:We conducted a prospective, randomized, double-blind study to compare analgesia obtained by wound infiltration using 29 ml of 0.25% bupivacaine alone, or with the addition of clonidine hydrochloride 150 micrograms. A third group received bupivacaine wound infiltration with clonidine 150 micrograms i.m. to control for ...

journal_title：British journal of anaesthesia

authors： Elliott S,Eckersall S,Fligelstone L,Jothilingam S

更新日期：1997-10-01 00:00:00

abstract：:An analysis of neuromuscular transmission has been made in phrenic nerve/diaphragm preparations from male rats aged 30 days or 110 days. The amplitude of miniature end-plate potentials was found to decrease with age, being 0.969 +/- SEM 0.058 mV at 30 days and 0.510 +/- SEM 0.031 mV at 110 days. Over the same period, ...

journal_title：British journal of anaesthesia

authors： Kelly SS,Roberts DV

更新日期：1977-03-01 00:00:00

abstract：:We tested the hypothesis that pressures exerted on the pharyngeal mucosa by the laryngeal mask airway (LMA) and cuffed oropharyngeal airway (COPA) differ, in 20 male and 20 female adult patients. Microchip pressure sensors were attached to the LMA and COPA at four similar anatomical locations (base of the tongue, late...

journal_title：British journal of anaesthesia

authors： Keller C,Brimacombe J

更新日期：1999-06-01 00:00:00

abstract：:The cardiorespiratory effects of increasing respiratory frequency were investigated in two groups of dogs ventilated mechanically with a system which minimized apparatus and anatomical deadspace. In one group minute volume was constant whilst frequency was increased; in the second group minute volume was increased to ...

journal_title：British journal of anaesthesia

authors： Chakrabarti MK,Sykes MK

更新日期：1980-05-01 00:00:00

abstract：:Sleep disordered breathing is a common problem affecting all age groups, particularly in association with certain other medical conditions and syndromes. The pathological consequences of the disorder may be severe, with significant implications for the perioperative management of sufferers. Research into the effects o...

journal_title：British journal of anaesthesia

authors： Loadsman JA,Hillman DR

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:The pathophysiology of the serotoninergic system in malignant hyperthermia (MH) is not completely understood. The serotonin-2 (5HT(2A)) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) induces typical MH symptoms, including skeletal muscle rigidity, an increase in body tempe...

journal_title：British journal of anaesthesia

authors： Gerbershagen MU,Wappler F,Fiege M,Kolodzie K,Weisshorn R,Szafarczyk W,Kudlik C,Schulte Am Esch J

更新日期：2003-08-01 00:00:00

abstract：:In an open study we have investigated the efficacy of 20 ml of 0.75% ropivacaine (7.5 mg ml-1) to provide extradural anaesthesia for elective Caesarean section. Plasma concentrations (total and free) were estimated in the mother and neonate. Anaesthesia was effective and safe. Plasma concentrations of ropivacaine in t...

journal_title：British journal of anaesthesia

authors： Morton CP,Bloomfield S,Magnusson A,Jozwiak H,McClure JH

更新日期：1997-07-01 00:00:00