Randomized controlled trial of the haemodynamic and recovery effects of xenon or propofol anaesthesia.

abstract：BACKGROUND:Aortocaval compression (ACC) can result in haemodynamic disturbances and uteroplacental hypoperfusion in parturients. Its detection is difficult because in most patients, sympathetic compensation results in no signs or symptoms. However, profound hypotension may develop after sympathectomy during regional an...

journal_title：British journal of anaesthesia

authors： Lee SW,Khaw KS,Ngan Kee WD,Leung TY,Critchley LA

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:There is considerable evidence that the use of tidal volumes <6 ml kg(-1) predicted body weight (PBW) reduces mortality in mechanically ventilated patients. We evaluated the effectiveness of using a large screen displaying delivered tidal volume in ml kg(-1) (PBW) for reducing tidal volumes. METHODS:We asse...

journal_title：British journal of anaesthesia

authors： Bourdeaux CP,Birnie K,Trickey A,Thomas MJ,Sterne J,Donovan JL,Benger J,Brandling J,Gould TH

更新日期：2015-08-01 00:00:00

abstract：:In 15 patients (ASA I-II) undergoing intraabdominal gynaecological surgery, muscle paralysis for tracheal intubation and surgery was achieved by a combined bolus and demand infusion of vecuronium. The initial loading dose of 67 micrograms kg-1 and the rate of subsequent infusion were determined by evaluation of the ta...

journal_title：British journal of anaesthesia

authors： Haraldsted VY,Nielsen JW,Joensen F,Dilling-Hansen B,Hasselstrøm L

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Tracheal tube tip and cuff positions of different cuffed paediatric tracheal tube brands in the trachea can vary with design. METHODS:Data from three clinical studies with measured tracheal lengths were pooled in a database including 422 children aged from birth to 16 yr. Dimensional data of seven cuffed pa...

journal_title：British journal of anaesthesia

authors： Kemper M,Imach S,Buehler PK,Thomas J,Dave M,Weiss M

更新日期：2018-08-01 00:00:00

abstract：:One explanation for diminished opioid analgesic efficacy is opioid-induced hyperalgesia (OIH). We report a case of OIH in an infant with gastroschisis, requiring multiple surgical interventions and prolonged sedation for ventilation. This is the first report of OIH in an infant. On day 41 of life after nine separate s...

journal_title：British journal of anaesthesia

authors： Hallett BR,Chalkiadis GA

更新日期：2012-01-01 00:00:00

abstract：:Tissue damage during surgery induces coagulation factors and activates platelets. Surgical pain may provoke release of catecholamines, leading to hypercoagulability. We have investigated the effect of surgical pain on blood coagulability and fibrinolysis in orthopaedic operations using tourniquets in 22 patients under...

journal_title：British journal of anaesthesia

authors： Kohro S,Yamakage M,Arakawa J,Kotaki M,Omote T,Namiki A

更新日期：1998-04-01 00:00:00

abstract：:All currently available aminoacylaniline local anaesthetics, except lignocaine, contain a chiral centre but are used as racemates, a fact usually ignored in pharmacokinetic studies. This study reports the cardiovascular effects, and the regional and total body clearances of the enantiomers of bupivacaine determined at...

journal_title：British journal of anaesthesia

authors： Rutten AJ,Mather LE,McLean CF

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:To determine the pharmacokinetics (PK) of a new i.v. formulation of paracetamol (Perfalgan) in children ≤15 yr of age. METHODS:After obtaining written informed consent, children under 16 yr of age were recruited to this study. Blood samples were obtained at 0, 15, 30 min, 1, 2, 4, 6, and 8 h after administr...

journal_title：British journal of anaesthesia

authors： Mohammed BS,Engelhardt T,Cameron GA,Cameron L,Hawksworth GM,Hawwa AF,McElnay J,Helms PJ,McLay JS

更新日期：2012-05-01 00:00:00

abstract：:Isolated, cultured rat pancreatic islets of Langerhans were incubated in medium containing glucose 2 or 20 mmol litre-1 and with glucose supplemented with midazolam 10, 100 or 1000 ng ml-1. Glucose 20 mmol litre-1 with the addition of noradrenaline 10 mumol litre-1 was used as a control. In contrast with noradrenaline...

journal_title：British journal of anaesthesia

authors： Desborough JP,Jones PM,Persaud SJ,Howell SL

更新日期：1993-02-01 00:00:00

abstract：:This review describes the laboratory evidence and microvascular mechanisms responsible for the beneficial effects of statins in sepsis. During sepsis, changes occur within the microcirculation including alterations in arteriolar tone influencing blood pressure, adaptations to endothelial cell integrity causing leakage...

journal_title：British journal of anaesthesia

authors： McGown CC,Brookes ZL

更新日期：2007-02-01 00:00:00

abstract：:Cardiovascular risk prediction using clinical risk factors is integral to both the European and the American algorithms for preoperative cardiac risk assessment and perioperative management for non-cardiac surgery. We have reviewed these risk factors and their ability to guide clinical decision making. We examine thei...

journal_title：British journal of anaesthesia

authors： Biccard BM,Rodseth RN

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Prolonged postoperative decrease in lung function is common after major upper abdominal surgery. Evidence suggests that ventilation with low tidal volumes may limit the damage during mechanical ventilation. We compared postoperative lung function of patients undergoing upper abdominal surgery, mechanically v...

journal_title：British journal of anaesthesia

authors： Treschan TA,Kaisers W,Schaefer MS,Bastin B,Schmalz U,Wania V,Eisenberger CF,Saleh A,Weiss M,Schmitz A,Kienbaum P,Sessler DI,Pannen B,Beiderlinden M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The pathophysiology of the serotoninergic system in malignant hyperthermia (MH) is not completely understood. The serotonin-2 (5HT(2A)) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) induces typical MH symptoms, including skeletal muscle rigidity, an increase in body tempe...

journal_title：British journal of anaesthesia

authors： Gerbershagen MU,Wappler F,Fiege M,Kolodzie K,Weisshorn R,Szafarczyk W,Kudlik C,Schulte Am Esch J

更新日期：2003-08-01 00:00:00

abstract：:Midazolam is often used for paediatric premedication. We have compared two methods of administering midazolam intranasally in 44 surgical day-case children allocated randomly to receive midazolam 0.2 mg kg-1 as drops or midazolam 0.1 mg kg-1 from an intranasal spray device. Behaviour was recorded on a four-point scale...

journal_title：British journal of anaesthesia

authors： Griffith N,Howell S,Mason DG

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Single-lung ventilation in infants and small children is challenging because suitable sizes of double-lumen cuffed tracheal tubes are not available. A 6-yr-old child required pulmonary saline washout for primary alveolar proteinosis, and therefore needed sequential single-lung ventilation in order to achieve...

journal_title：British journal of anaesthesia

authors： Wilson CA,Arthurs OJ,Black AE,Schievano S,Hunt C,van Hoog S,Wallis C,Sury MR

更新日期：2015-10-01 00:00:00

abstract：:Forty-five patients undergoing circumcision were allocated randomly to one of three study groups to compare topical analgesia with dorsal nerve block using the midline or lateral approach. Pain scores, side effects and analgesic requirements were recorded after surgery. Patients who received topical analgesia required...

journal_title：British journal of anaesthesia

authors： Chambers FA,Lee J,Smith J,Casey W

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:One major risk factor of the sitting position for neurosurgery is air embolism, especially in patients with persistent foramen ovale (PFO). The first aim of this prospective study was to evaluate a bedside method for detecting PFO using transcranial Doppler sonography (TCD) with contrast medium. A second aim...

journal_title：British journal of anaesthesia

authors： Engelhardt M,Folkers W,Brenke C,Scholz M,Harders A,Fidorra H,Schmieder K

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine has been proposed as a perineural local anaesthetic (LA) adjunct to prolong peripheral nerve block duration; however, results from our previous meta-analysis in the setting of brachial plexus block (BPB) did not support its use. Many additional randomized trials have since been published. We ...

journal_title：British journal of anaesthesia

authors： Vorobeichik L,Brull R,Abdallah FW

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Fluid administration to increase stroke volume index (SVi) is a cornerstone of haemodynamic resuscitation. We assessed the accuracy of SVi variation during a calibrated abdominal compression manoeuvre (ΔSVi-CAC) to predict fluid responsiveness in children. METHODS:Patients younger than 8 yr with acute circu...

journal_title：British journal of anaesthesia

authors： Jacquet-Lagrèze M,Tiberghien N,Evain JN,Hanna N,Courtil-Teyssedre S,Lilot M,Baudin F,Chardonnal L,Bompard D,Koffel C,Portefaix A,Javouhey E,Fellahi JL

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The elderly are perceived as a high-risk group for procedural sedation. Concern exists regarding the safety of sedation of this patient group by emergency physicians, particularly when using propofol. METHODS:We analysed prospectively collected data on patients aged 75 yr or older undergoing sedation betwee...

journal_title：British journal of anaesthesia

authors： Homfray G,Palmer A,Grimsmo-Powney H,Appelboam A,Lloyd G

更新日期：2018-12-01 00:00:00

abstract：:We studied the size 4 laryngeal mask airway (LMA) to test the hypothesis that oropharyngeal leak pressure and fibreoptic position improves with increasing cuff volume. After LMA insertion, 50 anaesthetized adult patients had the cuff inflated in 5-ml increments to 40 ml. Oropharyngeal leak pressure was optimal at 15 m...

journal_title：British journal of anaesthesia

authors： Keller C,Pühringer F,Brimacombe JR

更新日期：1998-08-01 00:00:00

abstract：:We have evaluated the clinical utility and blood propofol concentrations produced with two different infusion regimens for propofol, given to supplement 67% nitrous oxide-morphine anaesthesia. Patients received a standardized three-step infusion of propofol based either on body weight (weight-corrected group) or on a ...

journal_title：British journal of anaesthesia

authors： Sear JW,Glen JB

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:The Bispectral Index (BIS) monitor has been suggested as a potential tool to measure depth of sedation in paediatric intensive care unit (PICU) patients. The primary aim of our observational study was to assess the difference in BIS values between the left and right sides of the brain. Secondary aims were to...

journal_title：British journal of anaesthesia

authors： Froom SR,Malan CA,Mecklenburgh JS,Price M,Chawathe MS,Hall JE,Goodwin N

更新日期：2008-05-01 00:00:00

abstract：:We have studied 13 patients with diabetic nephropathy and 13 patients with uraemia of other origin undergoing renal transplantation, and 12 control patients undergoing general surgery. QTc dispersion and maximum QTc interval were calculated from the 12-lead ECG, and cardiovascular autonomic function tests were perform...

journal_title：British journal of anaesthesia

authors： Kirvelä M,Yli-Hankala A,Lindgren L

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:The AirWay Scope (AWS) is a fibreoptic device that allows for intubation without alignment of the oral, pharyngeal, and tracheal axes. It may be useful for patients with an unstable cervical-spine (C-spine) or when C-spine movement is undesirable. This study was conducted to fluoroscopically evaluate upper C...

journal_title：British journal of anaesthesia

authors： Maruyama K,Yamada T,Kawakami R,Hara K

更新日期：2008-10-01 00:00:00

abstract：:Blood flow to functionally different vascular beds was examined during a sodium nitroprusside infusion in 10 dogs anaesthetized with halothane (1 MAC) in oxygen. Blood flows were measured in the ascending aorta, and the coeliac, superior mesenteric, renal and iliac arteries. In two dogs, regional vascular impedance an...

journal_title：British journal of anaesthesia

authors： Bagshaw RJ,Cox RH,Campbell KB

更新日期：1977-08-01 00:00:00

abstract：:Before the induction of labour in 34 pregnant women 1.5% lignocaine 10 ml was injected into the lumbar extradural space at constant rates between 0.143 and 0.333 ml s-1. Injection pressures and residual pressures were recorded and the extent of analgesia to pinprick was assessed. No significant correlation was found b...

journal_title：British journal of anaesthesia

authors： Husemeyer RP,White DC

更新日期：1980-01-01 00:00:00

abstract：:In the prone knee-chest position the spread of plain 0.5% bupivacaine in the cerebrospinal fluid and associated haemodynamic changes may be different compared with the horizontal position. A randomized comparison was performed in 40 ASA I-II patients, aged 24-61 yr, undergoing lumbar disc surgery. Subarachnoid injecti...

journal_title：British journal of anaesthesia

authors： Laakso E,Pitkänen M,Kyttä J,Rosenberg PH

更新日期：1997-11-01 00:00:00

abstract：:Clinicians inevitably encounter patients who meet the diagnostic criteria for the metabolic syndrome (MetS); these criteria include central obesity, hypertension, atherogenic dyslipidaemia, and hyperglycaemia. Regardless of the variations in its definition, MetS may be associated with adverse outcomes in patients unde...

journal_title：British journal of anaesthesia

authors： Tzimas P,Petrou A,Laou E,Milionis H,Mikhailidis DP,Papadopoulos G

更新日期：2015-08-01 00:00:00

abstract：:Delirium commonly manifests in the postoperative period as a clinical syndrome resulting from acute brain dysfunction or encephalopathy. Delirium is characterized by acute and often fluctuating changes in attention and cognition. Emergence delirium typically presents and resolves within minutes to hours after terminat...

journal_title：British journal of anaesthesia

authors： Palanca BJA,Wildes TS,Ju YS,Ching S,Avidan MS

更新日期：2017-08-01 00:00:00