Abstract：
:Hypertensive patients were monitored for myocardial ischaemia during anaesthesia and surgery with the V5 lead of a standard electrocardiograph. Myocardial ischaemia was detected in 11 of 39 untreated hypertensive patients and in four of seven receiving therapy with a diuretic, but in none of 44 receiving atenolol. Fourteen of the atenolol-treated patients were receiving the drug on a long-term basis and the remaining 30 were treated acutely only on the morning of surgery. When myocardial ischaemia was observed, it was always associated with noxious stimulation and tachycardia, but a conspicuous increase in arterial pressure was not usually present. We conclude that myocardial ischaemia is prevalent during anaesthesia in untreated hypertensive patients, and that pretreatment with atenolol, but not diuretics, provides prophylaxis.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Stone JG,Foëx P,Sear JW,Johnson LL,Khambatta HJ,Triner Ldoi
10.1093/bja/61.6.675subject
Has Abstractpub_date
1988-12-01 00:00:00pages
675-9issue
6eissn
0007-0912issn
1471-6771pii
S0007-0912(17)47509-Xjournal_volume
61pub_type
临床试验,杂志文章,随机对照试验abstract：:Data from two published and one new meta-analysis were reviewed to compare the antiemetic efficacy of three different anaesthetic regimens: (i) propofol anaesthesia compared with another anaesthetic (control); (ii) anaesthesia without nitrous oxide compared with the same anaesthetic with nitrous oxide (control); (iii)...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,meta分析
doi：10.1093/bja/78.3.256
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:The purpose of this prospective study was to assess the blood-sparing effect, the quality of analgesia, and the incidence of side-effects of a low-dose regime of intrathecal opioids (ITO) when compared with those of a high-dose regime in scoliosis surgery in children. METHODS:Forty-six children were randoml...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aen025
更新日期：2008-04-01 00:00:00
abstract：:We have studied the efficacy of i.v. clonidine to suppress post-extradural shivering in parturients. Forty healthy parturients who received extradural block for labour (n = 20) or for Caesarean section (n = 20) and who required treatment for shivering after delivery were allocated randomly to two groups. Group I recei...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/71.2.294
更新日期：1993-08-01 00:00:00
abstract：:We have studied the effects of alfentanil administered intrathecally on somatosympathetic reflexes evoked by stimulation of radial and tibial nerves in 10 anaesthetized and paralysed dogs. In five animals, alfentanil was administered in doses of 100, 100, 200 and 400 micrograms in 0.8 ml and 800 micrograms in 1.6 ml p...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/68.5.503
更新日期：1992-05-01 00:00:00
abstract：:Spinal anaesthesia is the preferred anaesthetic technique for elective Caesarean deliveries. Hypotension is the most common side-effect and has both maternal and neonatal consequences. Different strategies have been attempted to prevent spinal-induced hypotension, including the use of low-dose bupivacaine. We conducte...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,meta分析,评审
doi：10.1093/bja/aer200
更新日期：2011-09-01 00:00:00
abstract：:We studied cardiovascular and catecholamine responses for 3 days in three groups of patients undergoing abdominal hysterectomy. The night before surgery and again 2 h before induction of anaesthesia, patients received the ACE inhibitor, ramipril, the beta 1 blocker, metoprolol, or placebo. In the actively treated grou...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/72.6.633
更新日期：1994-06-01 00:00:00
abstract：:Following antagonism of tubocurarine block with a mixture of atropine 20 microgram/kg and neostigmine 50 microgram/kg in 20 children, heart rate decreased from a control value of 110.4 beat/min to 90.1 at 5 min and 89.2 at 6 min (P less than 0.02). Stroke volume index did not change during the first 5 min from a contr...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/49.9.901
更新日期：1977-09-01 00:00:00
abstract：:Prolongation of the QT interval of the ECG represents an imbalance in cardiac autonomic function and may predict cardiac arrhythmia. Vagal activity protects against prolongation of the QT interval which may be associated with flattening of the T-wave of the ECG. The changes in QT interval, T-wave amplitude and respira...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/71.5.736
更新日期：1993-11-01 00:00:00
abstract：BACKGROUND:There has been a renewed interest in nitric oxide donor drugs, such as nitroglycerin, delivered by the inhalational route for treatment of pulmonary arterial hypertension (PAH). We investigated the acute effects of inhaled nitroglycerin on pulmonary and systemic haemodynamics in children with PAH associated ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/ael112
更新日期：2006-08-01 00:00:00
abstract：:Studies with an emulsion formulation of ICI 35 868 (2,6- diisopropylphenol ) indicate that this new formulation has anaesthetic properties in rats and mice, and haemodynamic effects in the mini-pig which are similar to those of the previously available Cremophor formulation. Administration of the emulsion formulation ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/56.6.617
更新日期：1984-06-01 00:00:00
abstract：:We describe a scavenging device, primarily for use during inhalation induction of anaesthesia in children; it was designed to optimize the often conflicting requirements of clinical acceptability and adequate gas collection. The performance was assessed in three ways. The device reduced the nitrous oxide concentration...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/64.1.117
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Cardiac output (CO) monitoring is helpful in the assessment of critically ill pregnant women, but invasive monitors are often unsuitable for use. We aimed to measure agreement between the non-invasive ultrasound cardiac output monitor (USCOM) and three-dimensional transthoracic echocardiography (3D-TTE) in p...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeu162
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:We investigated the effects of spinal and general anaesthesia and surgical tourniquet on acute pain and early recovery after total knee arthroplasty (TKA). METHODS:Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bja.2020.03.036
更新日期：2020-11-01 00:00:00
abstract：:Plasma concentrations of pancuronium were measured in nine patients undergoing surgery because of total biliary obstruction. When compared with the averaged model-independent pharmacokinetic parameters obtained for normal patients, the terminal half-life of 270 min was more than twice normal (132 min, P less than 0.00...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/49.11.1103
更新日期：1977-11-01 00:00:00
abstract：:Cerebral emboli detected by transcranial Doppler imaging were recorded in 20 patients undergoing multiple-vessel coronary artery bypass surgery, either with or without cardiopulmonary bypass, in a prospective unblinded comparative study. Emboli were recorded continuously from the time of pericardial incision until 10 ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/84.5.629
更新日期：2000-05-01 00:00:00
abstract：:Respiratory obstruction has been reported as a complication of carotid endarterectomy; the causes include traumatic mucosal oedema, direct tracheal compression by haematoma and oedema secondary to lymphatic and venous congestion. We report four cases of acute respiratory obstruction complicating carotid endarterectomy...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/76.1.156
更新日期：1996-01-01 00:00:00
abstract：:Frailty is a syndrome of cumulative decline across multiple physiological systems, which predisposes vulnerable adults to adverse events. Assessing vulnerable patients can potentially lead to interventions that improve surgical outcomes. Anaesthesiologists who care for older patients can identify frailty to improve pr...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1016/j.bja.2019.03.034
更新日期：2019-07-01 00:00:00
abstract：:We have examined interactions between midazolam, propofol and alfentanil using two end-points of light sedation (hypnosis) and anaesthesia. Quantal dose-response curves were determined in 400 female patients for the drugs individually and in combination. At the hypnotic end-point, interactions were analysed by fitting...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/69.2.162
更新日期：1992-08-01 00:00:00
abstract：:Summary While complex physiological mechanisms exist to regulate and optimize tissue oxygenation under various conditions, clinical and experimental evidence indicates that anaemia, unchecked, is associated with organ injury and unfavourable outcomes. More data (especially from human studies) are needed to answer ques...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aer350
更新日期：2011-12-01 00:00:00
abstract：:A new anaesthetic gas scavenging system is described. The resistance of the system appears to be low. When input gas flow rate in the system was zero or 150 litre min-1, misuse of the system produced pressure changes at its collecting points of 26 Pa subatmospheric and 630 Pa above atmospheric pressure, respectively. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/55.7.681
更新日期：1983-07-01 00:00:00
abstract：:Intraoperative awareness, with or without recall, continues to be a topic of clinical significance and neurobiological interest. In this article, we review evidence pertaining to the incidence, sequelae, and prevention of intraoperative awareness. We also assess which aspects of the complication are well understood (i...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aev034
更新日期：2015-07-01 00:00:00
abstract：:Midazolam 0.3 mg kg-1 was given as a single dose to three groups of children undergoing cardiac surgery to determine its pharmacokinetic profile in this situation. The first group, undergoing closed heart surgery, received the midazolam during the operation. The other groups underwent cardiopulmonary bypass (CPB) with...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/61.3.302
更新日期：1988-09-01 00:00:00
abstract：:The serum vasopressin (S-AVP) concentration, serum sodium concentration and osmolality, central venous pressure and fluid balance were measured during 10-min periods in 32 patients undergoing transurethral resection of the prostate. Concentration of S-AVP was unaffected by uncomplicated resection; irrigant absorption ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/63.3.330
更新日期：1989-09-01 00:00:00
abstract：:The use of di-isopropyl phenol (Diprivan) for induction of anaesthesia was assessed in doses ranging from 1 to 3 mg kg-1. With less than 1.75mg kg-1 not all patients were anaesthetized; 2.0 mg kg-1 appeared to be a satisfactory induction dose. Involuntary muscle movement, cough and hiccup at induction were rare with a...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/53.11.1197
更新日期：1981-11-01 00:00:00
abstract：:This review describes the laboratory evidence and microvascular mechanisms responsible for the beneficial effects of statins in sepsis. During sepsis, changes occur within the microcirculation including alterations in arteriolar tone influencing blood pressure, adaptations to endothelial cell integrity causing leakage...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/ael358
更新日期：2007-02-01 00:00:00
abstract：:Maternal haemorrhage is the leading cause of preventable maternal death worldwide and encompasses antepartum, intrapartum, and postpartum bleeding. This review highlights factors that predispose to severe bleeding, its management, and the most recent treatment and guidelines. Advances in obstetric care have provided p...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aep303
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Recent studies have concluded that i.v. dexamethasone can prolong the duration of peripheral nerve blockade. We hypothesized that a 4 mg dose would equally prolong the duration of psoas compartment blocks (PCBs) when compared with 8 mg, and that both doses would prolong the duration when compared with placeb...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bja.2017.11.073
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Treprostinil sodium improves haemodynamics and symptoms in pulmonary arterial hypertension (PAH) patients, but its subcutaneous (s.c.) administration can produce severe local site pain, and lead to discontinuation of vital treatment. Treprostinil is a prostacyclin analogue which stimulates prostacyclin recep...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aet308
更新日期：2014-02-01 00:00:00
abstract：:Quality of recovery after anaesthesia is an important measure of the early postoperative health status of patients. We attempted to develop a valid, reliable and responsive measure of quality of recovery after anaesthesia and surgery. We studied 160 patients and asked them to rate postoperative recovery using three me...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/oxfordjournals.bja.a013366
更新日期：2000-01-01 00:00:00
abstract：:We have compared the viability criteria of muscle bundles used in the in vitro contracture test for susceptibility to malignant hyperthermia (MH) in a group of 28 patients with various neuromuscular diseases (NMD) and 93 MH-related family patients. In the patients with NMD, this standard test gave one positive, six eq...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/72.1.93
更新日期：1994-01-01 00:00:00
