Intraoperative awareness: controversies and non-controversies.

abstract：:The effects of bolus doses of phenoperidine 1-2 mg i.v. either alone, or combined with pancuronium 2-4 mg, were investigated in seven patients in traumatic coma. Phenoperidine alone significantly reduced mean arterial pressure (MAP) by a mean (+/- SEM) of 13.2 (+/- 2.8) mm Hg. Overall there was no significant change i...

journal_title：British journal of anaesthesia

authors： Bingham RM,Hinds CJ

更新日期：1987-05-01 00:00:00

abstract：:Topical capsaicin formulations are used for pain management. Safety and modest efficacy of low-concentration capsaicin formulations, which require repeated daily self-administration, are supported by meta-analyses of numerous studies. A high-concentration capsaicin 8% patch (Qutenza™) was recently approved in the EU a...

journal_title：British journal of anaesthesia

authors： Anand P,Bley K

更新日期：2011-10-01 00:00:00

abstract：:The effect of the administration of propranolol 0.15 mg per kg body weight i.v. on the metabolic response to pelvic surgery was compared with results in similar patients who had not received propranolol. The only significant difference between the two groups was a lower plasma insulin concentration in the beta-blockad...

journal_title：British journal of anaesthesia

authors： Cooper GM,Paterson JL,Mashiter K,Hall GM

更新日期：1980-12-01 00:00:00

abstract：:As the route of breathing and use of airway apparatus such as mask, mouthpiece and noseclip can alter breathing pattern, this study has used the helium dilution method to estimate the effects of mouthpiece and mask breathing on functional residual capacity (FRC) in the supine position, and the change in FRC that occur...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the ci...

journal_title：British journal of anaesthesia

authors： Gögenur I,Wildschiøtz G,Rosenberg J

更新日期：2008-01-01 00:00:00

abstract：:This study was designed to observe the effects of i.v. fluid infusion on uterine activity during normal labour in women receiving an extradural block. Thirty-four women in spontaneous labour at term gestation were allocated randomly and prospectively to one of three i.v. pre-extradural fluid load groups: group A, no f...

journal_title：British journal of anaesthesia

authors： Cheek TG,Samuels P,Miller F,Tobin M,Gutsche BB

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Descriptions of the pharmacokinetics and metabolism of morphine and its metabolites in young children are scant. Previous studies have not differentiated the effects of size from those related to age during infancy. METHODS:Postoperative children 0-3 yr old were given an intravenous loading dose of morphine...

journal_title：British journal of anaesthesia

authors： Bouwmeester NJ,Anderson BJ,Tibboel D,Holford NH

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Experimental studies and investigations in patients with cardiac diseases suggest that opioids at clinical concentrations have no important direct effect on myocardial relaxation and contractility. In vivo data on the effect of remifentanil on myocardial function in humans are scarce. This study aimed to inv...

journal_title：British journal of anaesthesia

authors： Bolliger D,Seeberger MD,Kasper J,Skarvan K,Seeberger E,Lurati Buse G,Buser P,Filipovic M

更新日期：2011-04-01 00:00:00

abstract：:Ropivacaine is considered safer than bupivacaine, on the basis of experimental and human data that indicate a lower systemic toxicity. Here we report the occurrence of a single seizure after i.v. administration of ropivacaine 120 mg intended for extradural block in a patient having postpartum, tubal ligation. The only...

journal_title：British journal of anaesthesia

authors： Abouleish EI,Elias M,Nelson C

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is an α-2-receptor agonist which might be used as an additive to local anaesthetics for various regional anaesthetic techniques. We therefore designed this prospective, double-blinded, controlled volunteer study to investigate the effects of dexmedetomidine as an adjuvant to ropivacaine on pe...

journal_title：British journal of anaesthesia

authors： Marhofer D,Kettner SC,Marhofer P,Pils S,Weber M,Zeitlinger M

更新日期：2013-03-01 00:00:00

abstract：:The possibility of an interaction between diazepam and pancuronium bromide was investigated in six patients undergoing general anaesthesia maintained with fentanyl, droperidol and nitrous oxide. Neuromuscular blockade was controlled using a feedback mechanism which automatically adjusted the rate of injection of pancu...

journal_title：British journal of anaesthesia

authors： Asbury AJ,Henderson PD,Brown BH,Turner DJ,Linkens DA

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Early postoperative negative behaviour in preschool children after general anaesthesia is a common problem. The distinction between emergence delirium (ED) and pain is difficult, but management differs between the two. The aim of the current analysis was to identify individual observational variables that ca...

journal_title：British journal of anaesthesia

authors： Somaini M,Engelhardt T,Fumagalli R,Ingelmo PM

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Phonomyography (PMG) is a novel method to monitor neuromuscular block. It is non-invasive and can be applied to any muscle. It can be used interchangeably with mechanomyography (MMG). The staircase phenomenon has not been investigated for this method or at the corrugator supercilii muscle. The purpose of thi...

journal_title：British journal of anaesthesia

authors： Deschamps S,Trager G,Mathieu PA,Hemmerling TM

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Chronic pain is no longer an effective warning system, but a syndrome with co-morbidities and many causes, needing a careful evaluation. Questions remain about the pain behaviour of chronic pain patients compared with patients with acute pain, or healthy subjects that we investigated. METHODS:We compared th...

journal_title：British journal of anaesthesia

authors： Tuna T,Van Obbergh L,Van Cutsem N,Engelman E

更新日期：2018-09-01 00:00:00

abstract：:A possible means of rapid cooling in the emergency treatment of malignant hyperpyrexia, peritoneal dialysis using a cold dialysate, is described. Experimental observations in a young man on a regular peritoneal dialysis regime showed that significant heat extraction can be obtained when either a cool (20 degrees C) or...

journal_title：British journal of anaesthesia

authors： Gjessing J,Barsa J,Tomlin PJ

更新日期：1976-05-01 00:00:00

abstract：:Eight patients with a history of failed tracheal intubation during pregnancy were investigated by x-ray laryngoscopy after delivery. Partial elevation of the epiglottis with no view of glottic structures was found in five patients who were therefore considered to still present difficulty. In each of these five patient...

journal_title：British journal of anaesthesia

authors： Fahy L,Horton WA,Charters P

更新日期：1990-12-01 00:00:00

abstract：:We have evaluated the level of state and trait anxiety, neuroticism, extroversion and coping style as predictors of the effectiveness of patient-controlled analgesia (PCA) in 110 patients undergoing total abdominal hysterectomy. After operation patients were allocated to receive pain control with either PCA or i.m. in...

journal_title：British journal of anaesthesia

authors： Thomas V,Heath M,Rose D,Flory P

更新日期：1995-03-01 00:00:00

abstract：:Healthcare litigation in the UK continues to grow at an alarming rate, with claims against anaesthetists and critical care physicians increasing each year. This has led to a huge financial burden for the taxpayer and a sharp increase in professional indemnity fees for individual doctors. Although such litigation shoul...

journal_title：British journal of anaesthesia

authors： Adams JP,Bell MD,Bodenham AR

更新日期：2012-07-01 00:00:00

abstract：:We studied the effects of minor surgery and endotracheal intubation on postoperative breathing patterns. We measured breathing patterns and laryngeal resistance during the periods immediately before intubation (preoperative) and immediately after extubation following minor surgery (postoperative) in eight patients ana...

journal_title：British journal of anaesthesia

authors： Tanaka A,Isono S,Sato J,Nishino T

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The Bispectral Index (BIS) is a proprietary index of anaesthesia depth, which is correlated with the level of consciousness and probability of intraoperative recall. The present study investigates the use of a neural network technique to obtain a non-proprietary index of the depth of anaesthesia from the pro...

journal_title：British journal of anaesthesia

authors： Ortolani O,Conti A,Di Filippo A,Adembri C,Moraldi E,Evangelisti A,Maggini M,Roberts SJ

更新日期：2002-05-01 00:00:00

abstract：:We present an unusual case of hypercapnia and surgical emphysema during transanal endoscopic microsurgery, which led to delayed post-operative ventilatory failure. The hypercapnia and surgical emphysema were secondary to rectal insufflation with carbon dioxide used to facilitate visualization and resection of a rectal...

journal_title：British journal of anaesthesia

authors： Kerr K,Mills GH

更新日期：2001-04-01 00:00:00

abstract：:Midazolam is often used for paediatric premedication. We have compared two methods of administering midazolam intranasally in 44 surgical day-case children allocated randomly to receive midazolam 0.2 mg kg-1 as drops or midazolam 0.1 mg kg-1 from an intranasal spray device. Behaviour was recorded on a four-point scale...

journal_title：British journal of anaesthesia

authors： Griffith N,Howell S,Mason DG

更新日期：1998-12-01 00:00:00

abstract：:We have examined the effects of morphine in auricular myocardium from non-failing and failing human hearts. In both preparations morphine induced inhibition. These responses were not antagonized by naloxone. Comparison of mean IC30 values obtained in non-failing (3.9 (SEM 0.2) x 10(-8) mol litre-1) and failing (5010 (...

journal_title：British journal of anaesthesia

authors： Llobel F,Laorden ML

更新日期：1996-01-01 00:00:00

abstract：:Frailty is a syndrome of cumulative decline across multiple physiological systems, which predisposes vulnerable adults to adverse events. Assessing vulnerable patients can potentially lead to interventions that improve surgical outcomes. Anaesthesiologists who care for older patients can identify frailty to improve pr...

journal_title：British journal of anaesthesia

authors： Bentov I,Kaplan SJ,Pham TN,Reed MJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Prediction models to identify parturients who experience protracted pain, prolonged opioid use, and delayed self-assessed functional recovery are currently inadequate. METHODS:For this study, 213 nulliparous women who planned vaginal delivery were enrolled and assessed daily until they completed three outco...

journal_title：British journal of anaesthesia

authors： Komatsu R,Carvalho B,Flood P

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Clonidine is an alpha 2 adrenergic agonist with analgesic properties. This study aimed to see if the addition of clonidine to morphine when given by patient-controlled analgesia (PCA) would improve analgesia beyond the first 12 h after surgery. METHODS:Sixty patients undergoing lower abdominal surgery were ...

journal_title：British journal of anaesthesia

authors： Jeffs SA,Hall JE,Morris S

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Increasing numbers of older patients prescribed clopidogrel are presenting for urgent hip fracture surgery. Best practice for the management of clopidogrel therapy is unknown, although delays to surgery are associated with increased mortality. We investigated the influence of perioperative management of clop...

journal_title：British journal of anaesthesia

authors： Collyer TC,Reynolds HC,Truyens E,Kilshaw L,Corcoran T

更新日期：2011-12-01 00:00:00

abstract：:Seven patients are described in whom a prophylactic blood patch was instituted within 15 min of accidental dural puncture. Five of the patients received extradural anaesthesia before the blood patch, and one after the blood patch had been performed. In three of these patients further "top-up" doses of local anaestheti...

journal_title：British journal of anaesthesia

authors： Quaynor H,Corbey M

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Several medications have proved to be useful in preventing postoperative nausea and vomiting (PONV). However, routine antiemetic prophylaxis is not cost-effective. We evaluated the accuracy and discriminating power of an artificial neural network (ANN) to predict PONV. METHODS:We analysed data from 1086 in-...

journal_title：British journal of anaesthesia

authors： Peng SY,Wu KC,Wang JJ,Chuang JH,Peng SK,Lai YH

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for...

journal_title：British journal of anaesthesia

authors： Zuppa AF,Nicolson SC,Wilder NS,Ibla JC,Gottlieb EA,Burns KM,Stylianou M,Trachtenberg F,Ni H,Skeen TH,Andropoulos DB,Pediatric Heart Network Investigators.

更新日期：2019-12-01 00:00:00