Effects of morphine on atrial preparations obtained from nonfailing and failing human hearts.

abstract：:The arterial to end-tidal PCO2 difference (PaCO2-PE'CO2) was measured in five anaesthetized dogs during controlled ventilation at 0.25 Hz (15 b.p.m.) and during high frequency jet ventilation at 1, 3 and 5 Hz. Because of the slow response of the infra-red carbon dioxide analyser, satisfactory recordings of end-tidal c...

journal_title：British journal of anaesthesia

authors： Mortimer AJ,Cannon DP,Sykes MK

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The ilioinguinal/iliohypogastric nerve block is a popular regional anaesthetic technique for children undergoing inguinal surgery. The success rate is only 70-80% and complications may occur. A prospective randomized double-blinded study was designed to compare the use of ultrasonography with the conventiona...

journal_title：British journal of anaesthesia

authors： Willschke H,Marhofer P,Bösenberg A,Johnston S,Wanzel O,Cox SG,Sitzwohl C,Kapral S

更新日期：2005-08-01 00:00:00

abstract：:We have developed a simple, reliable method for rapid analysis of the partial pressure of volatile anaesthetic agents, based on a two-stage, head-space analysis. It is designed to solve the problems associated with reduced solubility of modern anaesthetics. After equilibration and analysis of a 2-ml sample of blood at...

journal_title：British journal of anaesthesia

authors： Smith MA,Sapsed-Byrne SM,Lockwood GG

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Perioperative warming is recommended for surgery under anaesthesia, however its role during Caesarean delivery remains unclear. This meta-analysis aimed to determine the efficacy of active warming on outcomes after elective Caesarean delivery. METHODS:We searched databases for randomized controlled trials u...

journal_title：British journal of anaesthesia

authors： Sultan P,Habib AS,Cho Y,Carvalho B

更新日期：2015-10-01 00:00:00

abstract：Background:Experimental studies suggest that mechanical cell washing to remove pro-inflammatory components that accumulate in the supernatant of stored donor red blood cells (RBCs) might reduce inflammation and organ injury in transfused patients. Methods:Cardiac surgery patients at increased risk of large-volume RBC ...

journal_title：British journal of anaesthesia

authors： Wozniak MJ,Sullo N,Qureshi S,Dott W,Cardigan R,Wiltshire M,Morris T,Nath M,Bittar N,Bhudia SK,Kumar T,Goodall AH,Murphy GJ

更新日期：2017-05-01 00:00:00

abstract：:Blood loss and the frequency of vomiting were assessed at 88 spontaneous vertex deliveries. An i.v. injection of oxytocin 10 u was as effective as ergometrine 0.5 mg in controlling bleeding from the uterus after delivery. The continuous infusion of a dilute solution of oxytocin in the first stage of labour was not fol...

journal_title：British journal of anaesthesia

authors： Moir DD,Amoa AB

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Ketamine-induced neuroapoptosis has been attributed to diverse stress-related mechanisms. Glycogen synthase kinase-3β (GSK-3β) is a multifunctional kinase that is active in neuronal development and linked to neurodegenerative disorders. We hypothesized that ketamine would enhance GSK-3β-induced neuroapopotos...

journal_title：British journal of anaesthesia

authors： Liu JR,Baek C,Han XH,Shoureshi P,Soriano SG

更新日期：2013-06-01 00:00:00

abstract：:We present a case where rocuronium 80 mg (3 x ED95) was used in a rapid sequence induction in a 80-kg pregnant patient with an open eye injury. The patient was also receiving magnesium 2 g h-1 i.v. for preterm labour. The expected duration for neuromuscular block of rocuronium in the absence of magnesium would be appr...

journal_title：British journal of anaesthesia

authors： Gaiser RR,Seem EH

更新日期：1996-11-01 00:00:00

abstract：:A technique of induction of anaesthesia using propanidid, lignocaine and suxamethonium is described, and the muscle fasciculations that follow it are shown to be significantly less than those accompanying induction with methohexitone and suxamethonium. ...

journal_title：British journal of anaesthesia

authors： Fry EN

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:Multiple cognitive and psychiatric disorders are associated with an increased tonic inhibitory conductance that is generated by α5 subunit-containing γ-aminobutyric acid type A (α5 GABAA) receptors. Negative allosteric modulators that inhibit α5 GABAA receptors (α5-NAMs) are being developed as treatments for...

journal_title：British journal of anaesthesia

authors： Manzo MA,Wang DS,Li WW,Pinguelo A,Popa MO,Khodaei S,Atack JR,Ross RA,Orser BA

更新日期：2020-12-30 00:00:00

abstract：:Cryoprecipitate, originally developed as a therapy for patients with antihaemophilic factor deficiency, or haemophilia A, has been in use for almost 50 yr. However, cryoprecipitate is no longer administered according to its original purpose, and is now most commonly used to replenish fibrinogen levels in patients with...

journal_title：British journal of anaesthesia

authors： Nascimento B,Goodnough LT,Levy JH

更新日期：2014-12-01 00:00:00

abstract：:We describe a six-compartment physiological model of the kinetics and dynamics of induction of anaesthesia with propofol in sheep. It includes a faithful description of initial bolus kinetics caused by accurate representations of the inter-relationships between initial vascular mixing, lung kinetics and cardiac output...

journal_title：British journal of anaesthesia

authors： Upton RN,Ludbrook GL

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...

journal_title：British journal of anaesthesia

authors： Chen A,Elia N,Dunaiceva J,Rudiger A,Walder B,Bollen Pinto B

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The pathophysiology of the serotoninergic system in malignant hyperthermia (MH) is not completely understood. The serotonin-2 (5HT(2A)) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) induces typical MH symptoms, including skeletal muscle rigidity, an increase in body tempe...

journal_title：British journal of anaesthesia

authors： Gerbershagen MU,Wappler F,Fiege M,Kolodzie K,Weisshorn R,Szafarczyk W,Kudlik C,Schulte Am Esch J

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:To determine whether temperature and haematocrit (Hct) alter the relationship between blood flow (BF) and blood flow velocity (BFV). METHODS:Using a transcranial Doppler apparatus, we measured the peak velocity of whole blood cells pumped by a cardiopulmonary bypass (CPB) circuit, through a 0.15-cm internal...

journal_title：British journal of anaesthesia

authors： Paut O,Bissonnette B

更新日期：2002-02-01 00:00:00

abstract：:Critical narrowing of the dependent airways was examined in anaesthetized dogs with closed chests. Two techniques were used, (a) "closing" volume (CV), measured from the expired nitrogen plateau and (b) tantalum bronchography, to measure the calibre of airways of 3-8 mm diameter in the upper (UZ), middle (MZ) and lowe...

journal_title：British journal of anaesthesia

authors： Jones JG,Graf PD,Lemen R

更新日期：1978-08-01 00:00:00

abstract：:Day-case anaesthesia requires rapidly eliminated anaesthetics which are relatively expensive. This multinational, multicentre European study assessed the relative costs of propofol or sevoflurane anaesthesia in 211 patients. Anaesthesia was induced and maintained with propofol in group 1, with propofol and sevoflurane...

journal_title：British journal of anaesthesia

authors： Smith I,Terhoeve PA,Hennart D,Feiss P,Harmer M,Pourriat JL,Johnson IA

更新日期：1999-10-01 00:00:00

abstract：:The face-grafting techniques are innovative and highly complex, requiring well-defined organization of all the teams involved. Subsequent to the first report in France in 2005, there have been 17 facial allograft transplantations performed worldwide. We describe anaesthesia and postoperative management, and the proble...

journal_title：British journal of anaesthesia

authors： Sedaghati-nia A,Gilton A,Liger C,Binhas M,Cook F,Ait-Mammar B,Scherrer E,Hivelin M,Lantieri L,Marty J,Plaud B

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Isoflurane has been reported to induce caspase-3 activation, which may induce neurotoxicity and contribute to the pathogenesis of Alzheimer's disease. However, the underlying mechanism is largely unknown, especially whether or not isoflurane can induce ryanodine receptors (RyRs)-associated endoplasmic reticu...

journal_title：British journal of anaesthesia

authors： Wang H,Dong Y,Zhang J,Xu Z,Wang G,Swain CA,Zhang Y,Xie Z

更新日期：2014-10-01 00:00:00

abstract：:We have studied haemodynamic responses to 0, 0.25, 0.5, 0.75 and 1 MAC isoflurane administration in 10 patients during a zero-order propofol infusion and normocapnia. Isoflurane reduced mean arterial pressure (MAP), systemic vascular resistance and left ventricular stroke work in a dose-dependent manner (29%, 38% and ...

journal_title：British journal of anaesthesia

authors： Verborgh C,Verbessem D,Camu F

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Echocardiography has been shown to positively impact on the management of the critically ill patient. However, many published studies have a significant bias towards inclusion of cardiothoracic patients. We present an audit of the impact of echocardiography on the management of patients in a district general...

journal_title：British journal of anaesthesia

authors： Orme RM,Oram MP,McKinstry CE

更新日期：2009-03-01 00:00:00

abstract：:In a prospective randomized multi-centre study, the mortality following internal fixation surgery for fracture of the upper femur was investigated in 538 elderly patients allocated to receive subarachnoid blockade or general (narcotic-relaxant) anaesthesia. The 28-day mortality was 6.6% with subarachnoid, and 5.9% wit...

journal_title：British journal of anaesthesia

authors： Davis FM,Woolner DF,Frampton C,Wilkinson A,Grant A,Harrison RT,Roberts MT,Thadaka R

更新日期：1987-09-01 00:00:00

abstract：:Maternal haemorrhage is the leading cause of preventable maternal death worldwide and encompasses antepartum, intrapartum, and postpartum bleeding. This review highlights factors that predispose to severe bleeding, its management, and the most recent treatment and guidelines. Advances in obstetric care have provided p...

journal_title：British journal of anaesthesia

authors： Walfish M,Neuman A,Wlody D

更新日期：2009-12-01 00:00:00

abstract：:Arterial pressure is still one of the most important measures in estimating the required dose of inhaled anaesthetics. It is measured easily and reacts rapidly which makes it suitable as a variable for feedback control of depth of anaesthesia. Fuzzy logic, a novel approach to feedback control, was used to control arte...

journal_title：British journal of anaesthesia

authors： Zbinden AM,Feigenwinter P,Petersen-Felix S,Hacisalihzade S

更新日期：1995-01-01 00:00:00

abstract：:Haemodynamic changes (supraventricular tachycardia, decreases in arterial pressure) were observed during laryngoscopy and intubation of the trachea in a patient receiving nifedipine and verapamil. Before the induced stresses of laryngoscopy and tracheal intubation, these drugs had controlled the patient's arterial pre...

journal_title：British journal of anaesthesia

authors： Gorven AM,Cooper GM,Prys-Roberts C

更新日期：1986-03-01 00:00:00

abstract：:The haemodynamic responses to isovolumic anaemia (dextran-for-blood exchange) were studied in seven dogs pretreated with propranolol 20 mg/kg body weight for 3 weeks. Adrenergic beta-receptor blockade did not prevent significant increases in heart rate (up to 19%). Cardiac output increased by about 20% while systemic ...

journal_title：British journal of anaesthesia

authors： Clarke TN,Foëx P,Roberts JG,Saner CA,Bennett MJ

更新日期：1980-03-01 00:00:00

abstract：:Delirium commonly manifests in the postoperative period as a clinical syndrome resulting from acute brain dysfunction or encephalopathy. Delirium is characterized by acute and often fluctuating changes in attention and cognition. Emergence delirium typically presents and resolves within minutes to hours after terminat...

journal_title：British journal of anaesthesia

authors： Palanca BJA,Wildes TS,Ju YS,Ching S,Avidan MS

更新日期：2017-08-01 00:00:00

abstract：:A computer program written mainly in a high level language (ALGOL), but with the sampling routine and certain calculations written in assembly language (SIR), has been developed to assess neuromuscular blockade in anaesthetized man by means of an Elliott 903 digital computer. The program allows the on-line real-time a...

journal_title：British journal of anaesthesia

authors： Perry IR,Worsley R,Sugai N,Payne JP

更新日期：1975-10-01 00:00:00

abstract：Background:The influence of different head and neck positions on the effectiveness of ventilation with the air-Q® self-pressurizing airway remains unevaluated. This study aimed to evaluate the influence of different head and neck positions on ventilation with the air-Q® SP airway. Methods:In this prospective, randomiz...

journal_title：British journal of anaesthesia

authors： Kim HJ,Lee K,Bai S,Kim MH,Oh E,Yoo YC

更新日期：2017-03-01 00:00:00

abstract：:The electroencephalogram (EEG) was monitored through all phases of enflurane anaesthesia in dental outpatients with a history of cerebral convulsions which had been well controlled with anticonvulsant drugs. Abnormal EEG activity which differed from the background activity was observed in three patients. Their case re...

journal_title：British journal of anaesthesia

authors： Yamashiro M,Sumitomo M,Furuya H

更新日期：1985-10-01 00:00:00