Circulatory responses of the dog to acute isovolumic anaemia in the presence of high-grade adrenergic beta-receptor blockade.

Abstract:

:The haemodynamic responses to isovolumic anaemia (dextran-for-blood exchange) were studied in seven dogs pretreated with propranolol 20 mg/kg body weight for 3 weeks. Adrenergic beta-receptor blockade did not prevent significant increases in heart rate (up to 19%). Cardiac output increased by about 20% while systemic vascular resistance decreased by the same proportion. Oxygen extraction increased from 24% to 35% and this was reflected by a decrease in mixed venous PO2 by 1.2 kPa. The modest hyperdynamic response of the circulation to haemodilution in the presence of high-grade adrenergic beta-receptor blockade is in sharp contrast with the large hyperdynamic response that has been reported in its absence and indicates that normal compensatory mechanisms are considerably impaired.

journal_name

Br J Anaesth

authors

Clarke TN,Foëx P,Roberts JG,Saner CA,Bennett MJ

subject

Has Abstract

pub_date

1980-03-01 00:00:00

pages

337-41

issue

3

eissn

0007-0912

issn

1471-6771

journal_volume

52

pub_type

杂志文章
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    doi:10.1093/bja/69.3.318

    authors: Mahajan RP,Laverty J

    更新日期:1992-09-01 00:00:00

  • Observations on extradural morphine analgesia in various pain conditions.

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    doi:10.1093/bja/52.3.247

    authors: Magora F,Olshwang D,Eimerl D,Shorr J,Katzenelson R,Cotev S,Davidson JT

    更新日期:1980-03-01 00:00:00

  • Validation and clinical utility of the Korean version of the Quality of Recovery-15 with enhanced recovery after surgery: a prospective observational cohort study.

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    pub_type: 杂志文章

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    更新日期:2020-10-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1093/bja/76.2.274

    authors: Selwyn DA,Raphael JH,Lambert DG,Langton JA

    更新日期:1996-02-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:1989-01-01 00:00:00

  • Comparison of morphine alone with morphine plus clonidine for postoperative patient-controlled analgesia.

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    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Jeffs SA,Hall JE,Morris S

    更新日期:2002-09-01 00:00:00

  • Changes in intragastric pressure on induction of anaesthesia.

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    pub_type: 杂志文章

    doi:10.1093/bja/56.8.873

    authors: Drummond GB,Park GR

    更新日期:1984-08-01 00:00:00

  • Effect of baricity on spinal anaesthesia with amethocaine.

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    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/52.6.589

    authors: Brown DT,Wildsmith JA,Covino BG,Scott DB

    更新日期:1980-06-01 00:00:00

  • Improved performance on cardiopulmonary exercise testing following DDDR pacemaker adjustment: a case report.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aet587

    authors: Bolsin S,Colson M,Ridley D,Ward C

    更新日期:2014-06-01 00:00:00

  • Validity and reliability of a postoperative quality of recovery score: the QoR-40.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.bja.a013366

    authors: Myles PS,Weitkamp B,Jones K,Melick J,Hensen S

    更新日期:2000-01-01 00:00:00

  • Emergence delirium or pain after anaesthesia--how to distinguish between the two in young children: a retrospective analysis of observational studies.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aev552

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    更新日期:2016-03-01 00:00:00

  • The suppression of spinal F-waves by propofol does not predict immobility to painful stimuli in humans.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aei283

    authors: Baars JH,Tas S,Herold KF,Hadzidiakos DA,Rehberg B

    更新日期:2006-01-01 00:00:00

  • Actions of the hypnotic anaesthetic, dexmedetomidine, on noradrenaline release and cell firing in rat locus coeruleus slices.

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    pub_type: 杂志文章

    doi:10.1093/bja/71.3.447

    authors: Jorm CM,Stamford JA

    更新日期:1993-09-01 00:00:00

  • Measurement of lung volume by multiple indicator dilution. Differences in apparent volumes of distribution of oxygen, nitrogen and argon.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/56.3.289

    authors: Black AM,Hahn CE,Maynard P,Scott IL

    更新日期:1984-03-01 00:00:00

  • Determination of cardiac output by ultrasound dilution technique in infants and children: a validation study against direct Fick principle.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aet382

    authors: Boehne M,Baustert M,Paetzel V,Köditz H,Schoof S,Happel CM,Bertram H

    更新日期:2014-03-01 00:00:00

  • Halothane and propofol differentially affect electroencephalographic responses to noxious stimulation.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aei208

    authors: Orth M,Barter L,Dominguez C,Atherley R,Carstens E,Antognini JF

    更新日期:2005-10-01 00:00:00

  • Quantitative assessment of extradural bupivacaine analgesia.

    abstract::Bupivacaine (0.5%) 20 ml was administered extradurally to six healthy volunteers. It was found that simultaneous application of 10 needles to the skin could evoke pain when analgesia was obtained to one needle stimulation. In addition, a laser beam was used as a quantitative technique to activate simultaneously many c...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/65.5.633

    authors: Adrendt-Nielsen L,Oberg B,Bjerring P

    更新日期:1990-11-01 00:00:00

  • Effect of age, gender and anaesthetic technique on the pharmacodynamics of atracurium.

    abstract::We have measured in 38 patients the plasma concentration profile of atracurium and its effect on the electromyographic first response of the train-of-four. One of three techniques was used to supplement anaesthesia with 66% nitrous oxide in oxygen, 0.9% isoflurane (end-tidal), 0.5% halothane (end-tidal) or midazolam 3...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/70.1.38

    authors: Parker CJ,Hunter JM,Snowdon SL

    更新日期:1993-01-01 00:00:00

  • Sevoflurane promotes the expansion of glioma stem cells through activation of hypoxia-inducible factors in vitro.

    abstract:BACKGROUND:Growing evidences indicate that inhalational anaesthetics can enhance the growth and malignant potential of tumour cells and may affect tumour recurrence after surgery. Tumour stem cells play a vital role in tumour recurrence. This study investigates the effect of sevoflurane on glioma stem cells (GSCs) in v...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeu402

    authors: Shi QY,Zhang SJ,Liu L,Chen QS,Yu LN,Zhang FJ,Yan M

    更新日期:2015-05-01 00:00:00

  • Postoperative use of a cough-assist device in avoiding prolonged intubation.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aef227

    authors: Marchant WA,Fox R

    更新日期:2002-10-01 00:00:00

  • Effect of propofol on heart rate, arterial pressure and digital plethysmograph variability.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/73.2.167

    authors: Robinson BJ,Buyck HC,Galletly DC

    更新日期:1994-08-01 00:00:00

  • Relationship between Bispectral Index, electroencephalographic state entropy and effect-site EC50 for propofol at different clinical endpoints.

    abstract:BACKGROUND:State entropy (SE) is a newly available monitor for depth of anaesthesia. We investigated whether the relationship between predicted effect-site propofol concentration and Bispectral Index (BIS) and SE values is useful for predicting loss of verbal contact and loss of consciousness during steady-state condit...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aei075

    authors: Iannuzzi M,Iannuzzi E,Rossi F,Berrino L,Chiefari M

    更新日期:2005-04-01 00:00:00

  • Aerosolized surfactant therapy for endotoxin-induced experimental acute respiratory distress syndrome in rats.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/87.2.266

    authors: Tashiro K,Yamada K,Konzaki T,Yamamoto K,Ohmura S,Kobayashi T,Suzuki Y

    更新日期:2001-08-01 00:00:00

  • Postoperative serum cholinesterase activity following successful renal transplantation.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/51.9.881

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    更新日期:1979-09-01 00:00:00

  • Leukemia inhibitory factor (LIF) potentiates antinociception activity and inhibits tolerance induction of opioids.

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    pub_type: 杂志文章

    doi:10.1093/bja/aew247

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    更新日期:2016-10-01 00:00:00

  • Interactive effect of morphine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.

    abstract::We studied the interactive effect of dexmedetomidine and morphine on gastric emptying and gastrointestinal transit in the rat. In one group of rats, to examine the interactive effect on gastrointestinal transit, the two drugs were injected i.p. in a fixed ratio (30: 1)--that of their ED50 values--in six doses (0.062-1...

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    pub_type: 杂志文章

    doi:10.1093/bja/80.1.63

    authors: Asai T,Mapleson WW,Power I

    更新日期:1998-01-01 00:00:00

  • Adverse effects of extradural and intrathecal opiates: report of a nationwide survey in Sweden.

    abstract::The Swedish Society of Anaesthetists conducted a nationwide retrospective survey of clinical experience with extradural and intrathecal opiates. Special interest was focused on the frequency and type of ventilatory depression. The questionnaire was answered by 84 of 93 departments (90%). Up to May 1981 extradural morp...

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    doi:10.1093/bja/54.5.479

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    更新日期:1982-05-01 00:00:00

  • Retraction notice to "Volume replacement in the surgical patient--does the type of solution make a difference?" [Br J Anaesth 84 (2000) 783-93].

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    doi:10.1016/j.bja.2020.07.036

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    pub_type: 杂志文章

    doi:10.1093/bja/aer386

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  • Suxamethonium-induced hyperkalaemia in patients with severe intra-abdominal infections.

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