Interactive effect of morphine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.

abstract：:Cerebral emboli detected by transcranial Doppler imaging were recorded in 20 patients undergoing multiple-vessel coronary artery bypass surgery, either with or without cardiopulmonary bypass, in a prospective unblinded comparative study. Emboli were recorded continuously from the time of pericardial incision until 10 ...

journal_title：British journal of anaesthesia

authors： Watters MP,Cohen AM,Monk CR,Angelini GD,Ryder IG

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:We investigated the effects of total i.v. anaesthesia (TIVA) and balanced anaesthesia (BAL) with sevoflurane on postoperative lung function in patients undergoing surgery in the prone position. METHODS:Sixty patients, aged 21-60 yr, undergoing elective lumbar disc surgery in the prone position were randomly...

journal_title：British journal of anaesthesia

authors： Tiefenthaler W,Pehboeck D,Hammerle E,Kavakebi P,Benzer A

更新日期：2011-02-01 00:00:00

abstract：:A double-blind trial was undertaken to compare the effects of trimeprazine tartrate (2 mg kg-1 or 4 mg kg-1) plus atropine 0.03 mg kg-1 for oral premedication of 192 children undergoing tonsillectomy. Demeanour before operation, side-effects after operation, recovery times and fluid balance were studied. Behaviour in ...

journal_title：British journal of anaesthesia

authors： Bramwell RG,Manford ML

更新日期：1981-08-01 00:00:00

abstract：:We investigated the effects of anaesthesia on dynamic nitric oxide production, concentrations of tetrahydrobiopterin and the accumulation of cyclic GMP (cGMP) in the rat central nervous system (CNS). Rats were assigned to anaesthesia with halothane, isoflurane, pentobarbital, diazepam, ketamine or xenon (n=6 per group...

journal_title：British journal of anaesthesia

authors： Galley HF,Le Cras AE,Logan SD,Webster NR

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:The objective of the present study was to investigate the effects of increasing doses of norepinephrine (NE) with or without arginine-vasopressin (AVP) on intestinal oxygen supply and jejunal mucosal tissue oxygen tension in an acute endotoxic pig model. METHODS:In this prospective, randomized, experimental...

journal_title：British journal of anaesthesia

authors： Maier S,Hasibeder W,Pajk W,Hengl C,Ulmer H,Hausdorfer H,Wurzinger B,Knotzer H

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:During normothermic cardiopulmonary bypass (CPB), the effect on propofol pharmacokinetics of changes in its binding to plasma proteins is consistent with the predictions of the well-stirred model of hepatic elimination for nonrestrictively cleared drug. However, whether changes in binding lead to clinically ...

journal_title：British journal of anaesthesia

authors： Takizawa E,Hiraoka H,Takizawa D,Goto F

更新日期：2006-02-01 00:00:00

abstract：:Although most local anaesthetic drugs are generally regarded as vasodilators at their site of injection, they produce systemic effects characterized by increases in peripheral resistance, cardiac output, arterial pressure heart rate. The direct depressive effects of the drugs are counterbalanced by increased sympathet...

journal_title：British journal of anaesthesia

authors： Blair MR

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:The use of lipid emulsions to reduce cardiac toxicity of local anaesthetics (LAs) has shown success in experimental studies and some clinical cases, and thus has been implemented in clinical practice. However, lipid treatment is usually given after the occurrence of neurological or cardiovascular symptoms of...

journal_title：British journal of anaesthesia

authors： Aumeier C,Kasdorf B,Gruber M,Busse H,Wiese CH,Zink W,Graf BM,Zausig YA

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:We investigated the effects of spinal and general anaesthesia and surgical tourniquet on acute pain and early recovery after total knee arthroplasty (TKA). METHODS:Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without...

journal_title：British journal of anaesthesia

authors： Palanne R,Rantasalo M,Vakkuri A,Madanat R,Olkkola KT,Lahtinen K,Reponen E,Linko R,Vahlberg T,Skants N

更新日期：2020-11-01 00:00:00

abstract：:We have studied the effect of doxapram on the rates of spontaneous and neostigmine-induced recovery from neuromuscular block with atracurium and vecuronium, by measurement of the time to recovery of T1 (first twitch in the train-of-four) from 25 to 75% of control (recovery index, RI). After each neuromuscular blocking...

journal_title：British journal of anaesthesia

authors： Cooper R,McCarthy G,Mirakhur RK,Maddineni VR

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Clinicians frequently warn patients of discomfort before potentially painful procedures, despite the lack of evidence that such communications are helpful. We aimed to compare two communications (one with, and the other without, a warning of a 'sting') immediately before i.v. cannulation in order to measure ...

journal_title：British journal of anaesthesia

authors： Dutt-Gupta J,Bown T,Cyna AM

更新日期：2007-12-01 00:00:00

abstract：:Following antagonism of tubocurarine block with a mixture of atropine 20 microgram/kg and neostigmine 50 microgram/kg in 20 children, heart rate decreased from a control value of 110.4 beat/min to 90.1 at 5 min and 89.2 at 6 min (P less than 0.02). Stroke volume index did not change during the first 5 min from a contr...

journal_title：British journal of anaesthesia

authors： Salem MR,Toyama T,Wong AY,Jacobs HK,Bennett EJ

更新日期：1977-09-01 00:00:00

abstract：:We have studied the effects of stepwise increasing infusion rates of propofol 200-500 micrograms kg-1 min-1 on blood concentrations of propofol and the disposition and clearance of a bolus dose of indocyanine green (ICG) 0.5 mg kg-1 in 10 acutely instrumented dogs. Drug concentrations and ICG clearance were measured 3...

journal_title：British journal of anaesthesia

authors： Sear JW,Diedericks J,Foex P

更新日期：1994-04-01 00:00:00

abstract：:A genetic disorder of the calcium releasing ryanodine receptor has recently been postulated in malignant hyperthermia (MH) and ryanodine-induced contractures differ between subjects who are malignant hyperthermia susceptible (MHS) and non-susceptible (MHN). We tested 39 patients from 26 families for MH, using the proc...

journal_title：British journal of anaesthesia

authors： Lenzen C,Roewer N,Wappler F,Scholz J,Kahl J,Blank M,Rumberger E,Schulte am Esch J

更新日期：1993-08-01 00:00:00

abstract：:All currently available aminoacylaniline local anaesthetics, except lignocaine, contain a chiral centre but are used as racemates, a fact usually ignored in pharmacokinetic studies. This study reports the cardiovascular effects, and the regional and total body clearances of the enantiomers of bupivacaine determined at...

journal_title：British journal of anaesthesia

authors： Rutten AJ,Mather LE,McLean CF

更新日期：1991-09-01 00:00:00

abstract：:We have measured in 38 patients the plasma concentration profile of atracurium and its effect on the electromyographic first response of the train-of-four. One of three techniques was used to supplement anaesthesia with 66% nitrous oxide in oxygen, 0.9% isoflurane (end-tidal), 0.5% halothane (end-tidal) or midazolam 3...

journal_title：British journal of anaesthesia

authors： Parker CJ,Hunter JM,Snowdon SL

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The pharmacokinetic profile of local anaesthetics is influenced by the mode of administration. We sought to compare the pharmacokinetics of two doses of ropivacaine after fascia iliaca compartment (FIC) block in children. METHODS:In this prospective, double-blind study, children received an FIC block as a p...

journal_title：British journal of anaesthesia

authors： Paut O,Schreiber E,Lacroix F,Meyrieux V,Simon N,Lavrut T,Camboulives J,Bruguerolle B

更新日期：2004-03-01 00:00:00

abstract：:The fate of gallamine triethiodide has been investigated in patients undergoing cholecystectomy with choledochostomy (group I), pelvic operations (group II) and orthopaedic operations (group III). Following a single i.v. injection of gallamine 2.5 mg kg(-1) the disappearance of the drug from the serum occurred in thre...

journal_title：British journal of anaesthesia

authors： Agoston S,Vermeer GA,Kersten UW,Scaf AH

更新日期：1978-04-01 00:00:00

abstract：:We have studied the complications associated with three techniques used to maintain extradural analgesia in labour: midwife top-up doses of 0.25% bupivacaine 10 ml, continuous infusion of 0.125% bupivacaine 10 ml h-1 and patient-controlled extradural analgesia (PCEA) with self-administered 3-ml bolus doses of 0.25% bu...

journal_title：British journal of anaesthesia

authors： Tan S,Reid J,Thorburn J

更新日期：1994-11-01 00:00:00

abstract：:The aim of this study was to find, using modern techniques, any histological differences in muscle biopsies between malignant hyperthermia (MH) susceptible (MHS), MH equivocal (MHE) and MH negative (MHN) patients. On the basis of the European MH contracture test carried out in 83 patients, 23 were shown to be MHS, nin...

journal_title：British journal of anaesthesia

authors： Mezin P,Payen JF,Bosson JL,Brambilla E,Stieglitz P

更新日期：1997-09-01 00:00:00

abstract：:Acetazolamide, a carbonic anhydrase inhibitor, may cause significant disturbances in carbon dioxide transport and elimination. In this study, end-tidal carbon dioxide monitoring has been used to study the correlation between arterial carbon dioxide (PaCO2) and end-tidal carbon dioxide partial pressure (PE'CO2) in rabb...

journal_title：British journal of anaesthesia

authors： Lee TS

更新日期：1994-08-01 00:00:00

abstract：:We have compared the viability criteria of muscle bundles used in the in vitro contracture test for susceptibility to malignant hyperthermia (MH) in a group of 28 patients with various neuromuscular diseases (NMD) and 93 MH-related family patients. In the patients with NMD, this standard test gave one positive, six eq...

journal_title：British journal of anaesthesia

authors： Adnet PJ,Krivosic-Horber RM,Krivosic I,Haudecoeur G,Reyford HG,Adamantidis MM,Medahoui H

更新日期：1994-01-01 00:00:00

abstract：:Arterial blood and expired gas samples were taken from 20 patients before operation and on the first day after upper abdominal surgery. After operation the patients were studied breathing air and also breathing 35% oxygen from a venturi-type mask. Preoperative Pao2 with age was exaggerated by operation. Pao2 after ope...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1975-04-01 00:00:00

abstract：:The effects of laudanosine, a metabolite of atracurium, on the behaviour of conscious mice, rats and dogs, and on cardiovascular function in conscious and anaesthetized dogs have been evaluated: EEG studies were performed in anaesthetized dogs. In mice and rats, i.v. bolus doses of laudanosine 10-20 mg kg-1, caused co...

journal_title：British journal of anaesthesia

authors： Chapple DJ,Miller AA,Ward JB,Wheatley PL

更新日期：1987-02-01 00:00:00

abstract：:We have investigated the incidence of regurgitation of gastric contents during general anaesthesia administered via a laryngeal mask airway (LMA) or face mask and Guedel airway in 56 patients with no risk factors for regurgitation. Patients swallowed a gelatin capsule containing methylene blue 10 min before induction ...

journal_title：British journal of anaesthesia

authors： Barker P,Langton JA,Murphy PJ,Rowbotham DJ

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Owing to complexities of measuring dead space, ventilatory failure is difficult to quantify in critical care. A simple, novel index called ventilatory ratio (VR) can quantify ventilatory efficiency at the bedside. The study objectives were to evaluate physiological properties of VR and examine its clinical a...

journal_title：British journal of anaesthesia

authors： Sinha P,Singh S,Hardman JG,Bersten AD,Soni N,Australia and New Zealand Intensive Care Society Clinical Trials Group.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The safety of performing spinal anaesthesia for both patients and anaesthetists alike in the presence of active infection with the novel coronavirus disease 2019 (COVID-19) is unclear. Here, we report the clinical characteristics and outcomes for both patients with COVID-19 and the anaesthetists who provided...

journal_title：British journal of anaesthesia

authors： Zhong Q,Liu YY,Luo Q,Zou YF,Jiang HX,Li H,Zhang JJ,Li Z,Yang X,Ma M,Tang LJ,Chen YY,Zheng F,Ke JJ,Zhang ZZ

更新日期：2020-06-01 00:00:00

abstract：:In 10 dogs, one carotid sinus was isolated from the systemic circulation without disturbing its sympathetic innervation. The isolated sinus was connected to a servo-controlled pressure generator which kept mean intrasinus pressure, pulse pressure, and frequency of pulsation constant. The carotid sinus baroreceptor ner...

journal_title：British journal of anaesthesia

authors： Behnia R,Koushanpour E,Shanks CA,McCarthy WJ

更新日期：1987-04-01 00:00:00

abstract：:Cytokine synthesis and release is an essential component of the innate immune system, but inappropriate, excessive production results in a generalized systemic inflammatory response which damages distant organs. Recent research has identified an immunomodulatory function of the vagus nerve whereby activation of the ef...

journal_title：British journal of anaesthesia

authors： Johnston GR,Webster NR

更新日期：2009-04-01 00:00:00

abstract：:BW 403C65, an isoquinolinium bisquaternary compound, was investigated for its neuromuscular blocking properties. In vitro in from preparations, low concentrations induced an increase in miniature endplate potentials (m.e.p.p.) frequency without altering their amplitude. With increasing concentrations m.e.p.p. frequenc...

journal_title：British journal of anaesthesia

authors： Post EL,Sokoll MD,Gergis SD,Dretchen KL,Cronnelly R

更新日期：1975-09-01 00:00:00