Abstract：
:We report the extradural administration of low-dose morphine in 10 ml of 10% dextrose (2-3 mg) to 98 adult patients with various types of acute and chronic pain. Extradural morphine injections were given either via a Tuohy needle (single or repeat injection) or via an extradural catheter. Pain relief was evaluated by subjective scoring and by the subsequent need for systemic analgesics. In 56% of patients, pain relief was considered good or excellent, in 24% it was fair, and in 20%, poor. The best results were after surgery and trauma and in patients with advanced peripheral vascular disease. The analgesia of each dose of extradural morphine lasted for 8 h (mean range 4-36 h). There was no motor, sensory or sympathetic blockade and no respiratory or haemodynamic complications. Dizziness and vomiting occurred in two patients, and urinary retention for about 12 h in three.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Magora F,Olshwang D,Eimerl D,Shorr J,Katzenelson R,Cotev S,Davidson JTdoi
10.1093/bja/52.3.247subject
Has Abstractpub_date
1980-03-01 00:00:00pages
247-52issue
3eissn
0007-0912issn
1471-6771pii
S0007-0912(17)47254-0journal_volume
52pub_type
杂志文章abstract：:We have documented the changes in gas exchange, haemodynamic state and associated physiological variables which occurred after graft reperfusion in 20 patients undergoing uncomplicated orthotopic liver transplantation. Gas exchange was measured during constant ventilation using a metabolic monitor. After reperfusion, ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/81.3.311
更新日期：1998-09-01 00:00:00
abstract：:The neuromuscular blocking effects of Org 9426, the 2-morpholino, 16-allyl-pyrrolidino derivative of the 3-desacetoxy analogue of vecuronium have been investigated in anaesthetized patients. Based on data from a pilot study, two doses, 250 and 500 micrograms kg-1 (estimated as the ED90 and 2 x ED90, respectively) were...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/64.4.521
更新日期：1990-04-01 00:00:00
abstract：:Neurological deterioration from intraspinal haematoma following insertion of a spinal needle is extremely rare. We present the case of a 28-yr-old female, who presented with complete paraplegia following attempted spinal anaesthesia for delivery of her third child. Space-occupying iatrogenic spinal haemorrhage from a ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/88.3.438
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:Descriptions of the pharmacokinetics and metabolism of morphine and its metabolites in young children are scant. Previous studies have not differentiated the effects of size from those related to age during infancy. METHODS:Postoperative children 0-3 yr old were given an intravenous loading dose of morphine...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aeh042
更新日期：2004-02-01 00:00:00
abstract：:A total of 1442 patients who had major gynaecological surgery were recruited into three multicentre studies using a standard general anaesthetic technique in order to assess the efficacy of various doses of orally administered ondansetron in the prevention of postoperative nausea and vomiting. A total of 1257 patients...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,meta分析,多中心研究,随机对照试验
doi：10.1093/bja/71.4.517
更新日期：1993-10-01 00:00:00
abstract：:It is known that propofol can have effects on atrioventricular node conduction. We report a case where administration of propofol was associated with termination of supraventricular tachycardia. Although a similar phenomenon has been reported in children, this is the first such case in an adult. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Pain management in craniotomy patients is challenging, with mild-to-moderate pain intensity, moderate-to-high risk of postoperative nausea and vomiting (PONV), and potentially catastrophic consequences of analgesic-related side-effects. The aim of this study was to determine whether i.v. parecoxib administer...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aer223
更新日期：2011-09-01 00:00:00
abstract：:In 1849 John Snow, already the leading anaesthetic practitioner and innovator of his day, made a historic contribution to the epidemiology of infectious disease by his famous study of the distribution of cholera around the area of Broad Street in London. We report on our experience as anaesthetists in a field hospital...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/75.6.810
更新日期：1995-12-01 00:00:00
abstract：:In theory, setting an infrared multi-gas analyser to measure a volatile anaesthetic different from that in the sampled gas mixture may cause interference with carbon dioxide and nitrous oxide readings. The theory was investigated during evaluation of the Dräger Cicero EM anaesthetic workstation for the Medical Devices...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/76.5.737
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:Hydroxyethyl starch (HES) may affect blood coagulation. We studied the effects of a modified, balanced, high-molecular weight [mean molecular weight (MW) 550 kDa], high-substituted [degree of substitution (DS) 0.7] HES preparation (Hextend) on coagulation in patients undergoing major abdominal surgery. METH...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验,收录出版
doi：10.1093/bja/aef242
更新日期：2002-11-01 00:00:00
abstract：:Thrombelastography (TEG) correlates with postoperative chest drain output in patients undergoing cardiopulmonary bypass (CPB). In vitro incubation with heparinase allows TEG monitoring during CPB, despite heparin anticoagulation. Hypothermia impairs coagulation, but these effects cannot be assessed by standard coagula...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/80.3.313
更新日期：1998-03-01 00:00:00
abstract：:The effect of alfentanil on sympathetic reflexes evoked by supramaximal electrical stimulation of the radial nerve has been observed in five dogs anaesthetized with alpha-chloralose, paralysed with suxamethonium and artificially ventilated. In five dogs during the infusion of alfentanil at a rate of 20 micrograms kg-1...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/61.4.441
更新日期：1988-10-01 00:00:00
abstract：:A retrospective study of serious non-fatal complications of extradural block in obstetric practice was carried out using a postal questionnaire. Two hundred and three obstetric units in the United Kingdom (responsible for 2,580,000 deliveries from 1982 to 1986 inclusive) responded. A total of 505,000 extradural blocks...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/64.5.537
更新日期：1990-05-01 00:00:00
abstract：BACKGROUND:To determine whether temperature and haematocrit (Hct) alter the relationship between blood flow (BF) and blood flow velocity (BFV). METHODS:Using a transcranial Doppler apparatus, we measured the peak velocity of whole blood cells pumped by a cardiopulmonary bypass (CPB) circuit, through a 0.15-cm internal...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/88.2.277
更新日期：2002-02-01 00:00:00
abstract：:A 24-yr-old male presented after a fishing accident in which he was pulled underwater by a rope attached to a crayfish pot. He was winched out of the water with the rope still around his neck, sustaining serious neck injuries that ultimately led to his death. After initial resuscitation, he remained fully conscious fo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/oxfordjournals.bja.a013484
更新日期：2000-04-01 00:00:00
abstract：:The water soluble benzodiazepine midazolam was compared with diazepam, in doses of 0.07 mg kg-1 and 0.15 mg kg-1 respectively, administered i.v. to 100 patients undergoing gastroscopy. The degree of sedation, ease of endoscopy and recovery were comparable in the two groups. The effects of both drugs on arterial pressu...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/55.8.773
更新日期：1983-08-01 00:00:00
abstract：:We have studied the complications associated with three techniques used to maintain extradural analgesia in labour: midwife top-up doses of 0.25% bupivacaine 10 ml, continuous infusion of 0.125% bupivacaine 10 ml h-1 and patient-controlled extradural analgesia (PCEA) with self-administered 3-ml bolus doses of 0.25% bu...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/73.5.619
更新日期：1994-11-01 00:00:00
abstract：:We describe a case of a 9-yr-old child with sickle cell disease complicated by abdominal vaso-occlusive crisis and priapism. Both complications were successfully treated with a combination of epidural local anesthetics and morphine. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/87.6.935
更新日期：2001-12-01 00:00:00
abstract：:We have examined the extradural space using a flexible extraduroscope in 74 patients undergoing extradural anaesthesia at the L2-3 interspace. Extraduroscopy showed that the extradural space becomes widely patent and the fatty tissue in the extradural space diminishes with increasing age. We postulate that these age-r...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/78.2.149
更新日期：1997-02-01 00:00:00
abstract：:Gastric (GP) and lower oesophageal sphincter pressures (LOSP) were measured in non-pregnant female volunteers (group I) and pregnant women with (group III) or without (group II) heartburn. Patients in early pregnancy had greater gastric pressures than group I. Mean barrier pressure (LOSP-GP) was significantly decrease...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/53.4.381
更新日期：1981-04-01 00:00:00
abstract：Background:Blood lactate is a strong predictor of mortality, and repeated blood lactate assays are recommended during surgery in high-risk patients. We hypothesized that the use of intravascular microdialysis incorporated in a central venous catheter would be interchangeable with the reference blood gas technique to mo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aex338
更新日期：2017-12-01 00:00:00
abstract：:Bispectral index (BIS) was assessed as a monitor of depth of anaesthesia during fentanyl and midazolam anaesthesia for coronary bypass surgery. In 10 patients given morphine premedication, anaesthesia was induced with a combination of midazolam and fentanyl and thereafter maintained with a continuous infusion of a mix...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/oxfordjournals.bja.a013587
更新日期：2000-06-01 00:00:00
abstract：:A blood-gas study of the respiratory effects of sodium nitroprusside during anaesthesia has shown a marked reduction in PaO2 when the drug was administered. After nitroprusside PaO2 returned to the previous values. It is suggested that the reduction in PaO2 is a result of an increased scatter of ventilation/perfusion ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/47.11.1205
更新日期：1975-11-01 00:00:00
abstract：:I.V. fluid therapy plays a fundamental role in the management of hospitalized patients. While the correct use of i.v. fluids can be lifesaving, recent literature demonstrates that fluid therapy is not without risks. Indeed, the use of certain types and volumes of fluid can increase the risk of harm, and even death, in...
journal_title：British journal of anaesthesia
pub_type： 共识发展会议,杂志文章,评审
doi：10.1093/bja/aeu300
更新日期：2014-11-01 00:00:00
abstract：:We have studied in eight rabbits the cardiovascular effects of midazolam, propofol and alfentanil with graded hypoxia. Central blood volume was reduced progressively by gradual inflation of a thoracic vena cava cuff so that cardiac index (CI) decreased at a constant rate. Under control conditions the haemodynamic resp...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/75.5.610
更新日期：1995-11-01 00:00:00
abstract：:We have conducted a randomized, double-blind comparison of 4% and 8% sevoflurane for induction of anaesthesia in unpremedicated patients aged more than 60 yr. Sevoflurane was inhaled in 50% nitrous oxide using a vital capacity breath technique, and mean, systolic and diastolic arterial pressures and heart rate were mo...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/82.1.20
更新日期：1999-01-01 00:00:00
abstract：BACKGROUND:Brachytherapy presents the anaesthetist with unique problems. Information on anaesthesia for brachytherapy, however, is limited. The aim of this paper is to report on our experience involving a large number of brachytherapy procedures. METHODS:A retrospective analysis of records of 1622 anaesthetic procedur...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aei301
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:None of the currently available hypnosis monitoring systems have evaluated balanced xenon anaesthesia. We investigated the performance of the bispectral index (BIS) and the composite A-line autoregressive index (cAAI) while comparing balanced xenon with sevoflurane anaesthesia. METHODS:Sixty patients underg...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aeq163
更新日期：2010-09-01 00:00:00
abstract：:We report two patients who developed skin necrosis following an intramuscular injection of non-steroidal anti-inflammatory drug into the anteriolateral area of their thigh. Both patients required further multiple operations and one developed life threatening septicaemia. They were left with disfiguring scars. Skin nec...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/88.1.139
更新日期：2002-01-01 00:00:00
abstract：:We have studied the effects of flow and dobutamine on systemic haemodynamic variables, oxygen delivery (DO2) and oxygen consumption (VO2) in 20 patients during cardiopulmonary bypass (CPB) with mild hypothermia (34 degrees C). In a subgroup of seven patients, we also studied the effects on gastric microcirculatory blo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/76.1.5
更新日期：1996-01-01 00:00:00
