Skin necrosis following injection of non-steroidal anti-inflammatory drug.

abstract：:The kinetics of morphine were studied during balanced anaesthesia in 10 patients undergoing lower abdominal or body surface surgery, and compared with those obtained in nine awake patients receiving morphine i.v. for the relief of chronic non-cancer pain. All patients received morphine sulfphate pentahydrate 10 mg i.v...

journal_title：British journal of anaesthesia

authors： Sear JW,Hand CW,Moore RA,McQuay HJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Anaesthesia and surgery are associated with impairment of the immune system expressed as an excessive proinflammatory immune response and suppression of cell-mediated immunity that may affect the course of the postoperative period. Addition of anaesthetic agents capable of attenuating the alterations in peri...

journal_title：British journal of anaesthesia

authors： Beilin B,Rusabrov Y,Shapira Y,Roytblat L,Greemberg L,Yardeni IZ,Bessler H

更新日期：2007-10-01 00:00:00

abstract：:A blind comparison was made of butorphanol 2 mg with morphine 10 mg i.m. as the sole premedication in four groups, each of 10 women, undergoing total abdominal hysterectomy. On both subjective and objective grounds, butorphanol was as effective as morphine with the advantage of fewer unwanted side-effects, although on...

journal_title：British journal of anaesthesia

authors： Laffey DA,Kay NH

更新日期：1984-04-01 00:00:00

abstract：:As constant hypoxaemia itself may trigger development of apnoea and periodic breathing, we have studied the effect of oxygen therapy on the occurrence of late postoperative episodic hypoxaemia. Thirty-five patients without cardiopulmonary disease and undergoing elective total hip replacement were monitored with a puls...

journal_title：British journal of anaesthesia

authors： Rosenberg J,Pedersen MH,Gebuhr P,Kehlet H

更新日期：1992-01-01 00:00:00

abstract：:In a prospective randomized multi-centre study, the mortality following internal fixation surgery for fracture of the upper femur was investigated in 538 elderly patients allocated to receive subarachnoid blockade or general (narcotic-relaxant) anaesthesia. The 28-day mortality was 6.6% with subarachnoid, and 5.9% wit...

journal_title：British journal of anaesthesia

authors： Davis FM,Woolner DF,Frampton C,Wilkinson A,Grant A,Harrison RT,Roberts MT,Thadaka R

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:It was hypothesized that xenon would stabilize mean arterial pressure (MAP) in haemorrhagic shock, recovery, and volume resuscitation, because a higher MAP has been observed with xenon, when compared with isoflurane anaesthesia. The responses to haemorrhage and subsequent volume replacement were therefore co...

journal_title：British journal of anaesthesia

authors： Baumert JH,Hecker KE,Hein M,Reyle-Hahn SM,Horn NA,Rossaint R

更新日期：2005-06-01 00:00:00

abstract：:A retrospective study was carried out to determine analgesic requirements in a group of orthopaedic outpatients (n = 145) and oral surgery inpatients (n = 172). The orthopaedic patients received a codeine-paracetamol premedication, an opioid during operation, or no analgesic. Less than 50% of the orthopaedic patients ...

journal_title：British journal of anaesthesia

authors： Campbell WI

更新日期：1990-05-01 00:00:00

abstract：:Using human nasal cytological brushings, we have investigated the effects of morphine on ciliary function by measurement of cilia beat frequency in vitro, and we have also determined opioid receptor binding in these specimens. We obtained ciliated samples from seven volunteers, and measured cilia beat frequency using ...

journal_title：British journal of anaesthesia

authors： Selwyn DA,Raphael JH,Lambert DG,Langton JA

更新日期：1996-02-01 00:00:00

abstract：:Placental transfer of 14C-dimethyltubocurarine (14C-dmtc) was studied during Caesarean section. Liquid scintillation counting was used for determination of 14C activity from the maternal and foetal blood samples. Paper chromatography was used to confirm the stability of 14C-dmtc. In all cases 14C-dmtc was able to cros...

journal_title：British journal of anaesthesia

authors： Kivalo I,Saarikoski S

更新日期：1976-03-01 00:00:00

abstract：:A simple method of adapting a pressure-cycled ventilator of the flow generator type to ventilate patients on a circle-absorber anaesthetic system is described. Standard lengths of corrugated black rubber tubing are placed between the ventilator and the circle-absorber is deadspace, replacing the reservoir bag. The per...

journal_title：British journal of anaesthesia

authors： Jeal DE

更新日期：1977-03-01 00:00:00

abstract：:Metoclopramide hastens emptying of the stomach. Since it may be given to patients before operation, the sedative and toxic effects of 10- and 20-mg does given i.m. were studied in patients and student volunteers. Saline and diazepam 10 mg were used as placebo and reference drugs. Neither dose of metoclopramide had as ...

journal_title：British journal of anaesthesia

authors： Dundee JW,Clarke RS,Howard PJ

更新日期：1974-07-01 00:00:00

abstract：:Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea and vomiting (IO...

journal_title：British journal of anaesthesia

authors： Mishriky BM,Habib AS

更新日期：2012-03-01 00:00:00

abstract：:Intrathecal midazolam causes antinociception by combining with spinal cord benzodiazepine receptors. This effect is reversible with doses of naloxone, suggesting involvement of spinal kappa or delta but not mu opioid receptors. The antinociceptive effects of intrathecally administered drugs in the spinal cord were dem...

journal_title：British journal of anaesthesia

authors： Goodchild CS,Guo Z,Musgreave A,Gent JP

更新日期：1996-12-01 00:00:00

abstract：:In the prone knee-chest position the spread of plain 0.5% bupivacaine in the cerebrospinal fluid and associated haemodynamic changes may be different compared with the horizontal position. A randomized comparison was performed in 40 ASA I-II patients, aged 24-61 yr, undergoing lumbar disc surgery. Subarachnoid injecti...

journal_title：British journal of anaesthesia

authors： Laakso E,Pitkänen M,Kyttä J,Rosenberg PH

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:The optimal dose of oxytocin at Caesarean section is unclear. Oxytocin may cause adverse cardiovascular effects, including tachycardia and hypotension, whereas an inadequate dose can result in increased uterine bleeding. We compared the effects of two doses of oxytocin in a randomized double-blind trial. ME...

journal_title：British journal of anaesthesia

authors： Sartain JB,Barry JJ,Howat PW,McCormack DI,Bryant M

更新日期：2008-12-01 00:00:00

abstract：:The clinical understanding of the dynamics of myocardial contraction is hampered by an over-simplified interpretation of the intramural pattern of force generation. This limits the anaesthetist's knowledge of the direct effects of commonly used anaesthetics. A discrimination between a negative inotropic effect and cha...

journal_title：British journal of anaesthesia

authors： Lunkenheimer PP,Redmann K,Whimster WF,Theissen J,Frieling G,Lunkenheimer A

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Isoflurane and other volatile anaesthetics have a cardioprotective effect and limit myocardial infarct size to the same extent as ischaemic preconditioning. Phosphatidylinositol-3-kinase (PI3K) was found to play a key role in myocardial protection by ischaemic preconditioning. The aim of the present investig...

journal_title：British journal of anaesthesia

authors： Raphael J,Rivo J,Gozal Y

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Dynamic variables reliably predict fluid responsiveness (FR) in adults, but no data are available regarding their performance in infants. The aim of this prospective study was to assess whether pulse pressure variation (PPV) and stroke volume variation (SVV), in contrast to central venous pressure (CVP) and ...

journal_title：British journal of anaesthesia

authors： Renner J,Broch O,Duetschke P,Scheewe J,Höcker J,Moseby M,Jung O,Bein B

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Patients with hip fractures are usually frail and elderly with a 30-day mortality in excess of 10% in European series. Perioperative morbidity is often multifactorial in nature, and unimodal interventions will not necessarily decrease mortality. The purpose of this prospective study was to analyse causes o...

journal_title：British journal of anaesthesia

authors： Foss NB,Kehlet H

更新日期：2005-01-01 00:00:00

abstract：:We studied 100 healthy women undergoing outpatient gynaecological laparoscopy in a randomized, double-blind and placebo-controlled study to evaluate the effect of neostigmine on postoperative nausea and vomiting (PONV). After induction of anaesthesia with propofol, anaesthesia was maintained with sevoflurane and 66% n...

journal_title：British journal of anaesthesia

authors： Nelskylä K,Yli-Hankala A,Soikkeli A,Korttila K

更新日期：1998-11-01 00:00:00

abstract：:A simple mathematical model of the chest wall was constructed so that during tidal breathing the relative volume contributions of the rib cage and abdomen/diaphragm could be measured in man, using four mercury-in-rubber strain gauges around the trunk. From the dimensions of the trunk and the change in circumference de...

journal_title：British journal of anaesthesia

authors： Faithfull D,Jones JG,Jordan C

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Plethysmographic variability index (PVI) is an accurate predictor of fluid responsiveness in mechanically ventilated patients. However, the site of measurement of the plethysmographic waveform impacts its morphology and its respiratory variation. The goal of this study was to investigate the ability of PVI t...

journal_title：British journal of anaesthesia

authors： Desgranges FP,Desebbe O,Ghazouani A,Gilbert K,Keller G,Chiari P,Robin J,Bastien O,Lehot JJ,Cannesson M

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Transtracheal jet ventilation (TTJV) is recommended in several airway guidelines as a potentially life-saving procedure during the 'Can't Intubate Can't Oxygenate' (CICO) emergency. Some studies have questioned its effectiveness. METHODS:Our goal was to determine the complication rates of TTJV in the CICO e...

journal_title：British journal of anaesthesia

authors： Duggan LV,Ballantyne Scott B,Law JA,Morris IR,Murphy MF,Griesdale DE

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Patients undergoing non-cardiac, non-vascular surgery are at risk of major cardiovascular complications. In non-cardiac surgery, troponin elevation has previously been shown to be an independent predictor of major adverse cardiac events and postoperative mortality; however, a majority of studies have focused...

journal_title：British journal of anaesthesia

authors： Ekeloef S,Alamili M,Devereaux PJ,Gögenur I

更新日期：2016-11-01 00:00:00

abstract：:A randomized, double-blind study of 40 women was performed to compare patient controlled anaesthesia (PCA) morphine requirements after spinal anaesthesia for elective Caesarean section. The women received 0.2 mg of either morphine or diamorphine mixed with 0.5% bupivacaine in 8% dextrose. There were no significant dif...

journal_title：British journal of anaesthesia

authors： Husaini SW,Russell IF

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:This study compared the efficacy of topical anaesthesia with levobupivacaine 0.75% vs lidocaine 2% during cataract surgery by phacoemulsification. METHODS:A prospective, randomized, double-blind study comparing two agents for topical anaesthesia in cataract surgery. Two hundred and forty-six consecutive pat...

journal_title：British journal of anaesthesia

authors： Fernández SA,Dios E,Diz JC

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Chronic pain is no longer an effective warning system, but a syndrome with co-morbidities and many causes, needing a careful evaluation. Questions remain about the pain behaviour of chronic pain patients compared with patients with acute pain, or healthy subjects that we investigated. METHODS:We compared th...

journal_title：British journal of anaesthesia

authors： Tuna T,Van Obbergh L,Van Cutsem N,Engelman E

更新日期：2018-09-01 00:00:00

abstract：:The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally painful orthopaedic hand surgery (trapeziectomy). Further investigations revealed a lifelong history...

journal_title：British journal of anaesthesia

authors： Habib AM,Okorokov AL,Hill MN,Bras JT,Lee MC,Li S,Gossage SJ,van Drimmelen M,Morena M,Houlden H,Ramirez JD,Bennett DLH,Srivastava D,Cox JJ

更新日期：2019-08-01 00:00:00

abstract：:We have documented the changes in gas exchange, haemodynamic state and associated physiological variables which occurred after graft reperfusion in 20 patients undergoing uncomplicated orthotopic liver transplantation. Gas exchange was measured during constant ventilation using a metabolic monitor. After reperfusion, ...

journal_title：British journal of anaesthesia

authors： Walsh TS,Hopton P,Garden OJ,Lee A

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the ci...

journal_title：British journal of anaesthesia

authors： Gögenur I,Wildschiøtz G,Rosenberg J

更新日期：2008-01-01 00:00:00