Measurement of the relative contributions of rib cage and abdomen/diaphragm to tidal breathing in man.

abstract：:We evaluated prospectively the use of Gram staining of protected pulmonary specimens to allow the early diagnosis of ventilator-associated pneumonia (VAP), compared with the use of 60 bronchoscopic protected specimen brushes (PSB) and 126 blinded plugged telescopic catheters (PTC) obtained from 134 patients. Gram stai...

journal_title：British journal of anaesthesia

authors： Mimoz O,Karim A,Mazoit JX,Edouard A,Leprince S,Nordmann P

更新日期：2000-11-01 00:00:00

abstract：:We have studied the effect of doxapram on the rates of spontaneous and neostigmine-induced recovery from neuromuscular block with atracurium and vecuronium, by measurement of the time to recovery of T1 (first twitch in the train-of-four) from 25 to 75% of control (recovery index, RI). After each neuromuscular blocking...

journal_title：British journal of anaesthesia

authors： Cooper R,McCarthy G,Mirakhur RK,Maddineni VR

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the ci...

journal_title：British journal of anaesthesia

authors： Gögenur I,Wildschiøtz G,Rosenberg J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:This study was undertaken to compare the effects of general anaesthesia (GA) and spinal anaesthesia (SA) on the need for postoperative hospitalization and early postoperative comfort in patients undergoing fast-track total knee arthroplasty (TKA). METHODS:One hundred and twenty subjects were randomly alloca...

journal_title：British journal of anaesthesia

authors： Harsten A,Kehlet H,Toksvig-Larsen S

更新日期：2013-09-01 00:00:00

abstract：:We have compared the effects of dexmedetomidine and propofol on endocrine, metabolic, inflammatory and cardiovascular responses in patients in the intensive care unit (ICU) after major surgery. Twenty patients who were expected to require 8 h of post-operative sedation and ventilation were allocated randomly to receiv...

journal_title：British journal of anaesthesia

authors： Venn RM,Bryant A,Hall GM,Grounds RM

更新日期：2001-05-01 00:00:00

abstract：:In a randomized, double-blind study, we have examined the stereoselective disposition and pharmacodynamic characteristics of ketamine in surgical patients after i.v. administration of S(+)-ketamine 1 mg/kg body weight (25 patients) or racemic ketamine 2 mg/kg body weight (25 patients). S(+)-Ketamine was not inverted t...

journal_title：British journal of anaesthesia

authors： Geisslinger G,Hering W,Thomann P,Knoll R,Kamp HD,Brune K

更新日期：1993-06-01 00:00:00

abstract：:Maternal and umbilical venous serum naloxone concentrations were measured after the i.v. (30 mothers) or i.m. (seven mothers) injection of naloxone 400 micrograms. Following i.v. naloxone there was rapid transfer to the fetus and therapeutic plasma concentrations could be expected in 1 or 2 min. However, following i.m...

journal_title：British journal of anaesthesia

authors： Hibbard BM,Rosen M,Davies D

更新日期：1986-01-01 00:00:00

abstract：:We have tested the hypothesis that intradermal testing is a more effective method for determining the drug responsible for anaesthetic anaphylactic reactions than prick testing in 212 consecutive patients, aged more than 10 yr, referred to an anaesthetic allergy clinic over a 4-yr period. The study was a prospective, ...

journal_title：British journal of anaesthesia

authors： Fisher MM,Bowey CJ

更新日期：1997-07-01 00:00:00

abstract：:Many indices are used to quantify pulmonary oxygen transfer. Indices that use only measurements from arterial blood and inspired gas assume a constant C(a-v)O2. Though variations in C(a-v)O2 are recognized, indices such as PaO2/FIO2 remain popular and are often considered the best measure of pulmonary oxygen transfer ...

journal_title：British journal of anaesthesia

authors： Nirmalan M,Willard T,Columb MO,Nightingale P

更新日期：2001-04-01 00:00:00

abstract：Background.:Perioperative administration of cefazolin reduces the incidence of perioperative infections. Intraoperative re-dosing of cefazolin is commonly given between 2 and 5 h after the initial dose. This study was undertaken to determine whether intraoperative continuous infusions of cefazolin achieve better probab...

journal_title：British journal of anaesthesia

authors： Naik BI,Roger C,Ikeda K,Todorovic MS,Wallis SC,Lipman J,Roberts JA

更新日期：2017-06-01 00:00:00

abstract：:Forty patients who had undergone coronary artery graft surgery and who required vasodilator therapy for postoperative hypertension were given infusions of either alfentanil or morphine together with bolus doses of midazolam for sedation and analgesia while ventilation was controlled artificially. Sodium nitroprusside ...

journal_title：British journal of anaesthesia

authors： McMenemin IM,Church JA,Kenny GN

更新日期：1988-12-01 00:00:00

abstract：:Seventeen patients received morphine 0.2 mgkg-1 in a 10% dextrose solution i.m. (n = 5), extradurally (n = 6) and intrathecally (n = 6) for pain after operation. Morphine was measured in plasma by radioimmunoassay. Plasma immunoreactive morphine concentration was significantly less after intrathecal administration aft...

journal_title：British journal of anaesthesia

authors： Chauvin M,Samii K,Schermann JM,Sandouk P,Bourdon R,Viars P

更新日期：1981-09-01 00:00:00

abstract：:We studied the effects of minor surgery and endotracheal intubation on postoperative breathing patterns. We measured breathing patterns and laryngeal resistance during the periods immediately before intubation (preoperative) and immediately after extubation following minor surgery (postoperative) in eight patients ana...

journal_title：British journal of anaesthesia

authors： Tanaka A,Isono S,Sato J,Nishino T

更新日期：2001-11-01 00:00:00

abstract：:Intragastric pressure was measured in 20 patients before, and immediately after, the induction of anaesthesia with thiopentone. Intragastric pressure decreased in patients whose weights were the same as or less than expected, and increased in five of seven patients whose weights were greater than expected (P = 0.0013)...

journal_title：British journal of anaesthesia

authors： Drummond GB,Park GR

更新日期：1984-08-01 00:00:00

abstract：:BW 403C65, an isoquinolinium bisquaternary compound, was investigated for its neuromuscular blocking properties. In vitro in from preparations, low concentrations induced an increase in miniature endplate potentials (m.e.p.p.) frequency without altering their amplitude. With increasing concentrations m.e.p.p. frequenc...

journal_title：British journal of anaesthesia

authors： Post EL,Sokoll MD,Gergis SD,Dretchen KL,Cronnelly R

更新日期：1975-09-01 00:00:00

abstract：:We have examined interactions between midazolam, propofol and alfentanil using two end-points of light sedation (hypnosis) and anaesthesia. Quantal dose-response curves were determined in 400 female patients for the drugs individually and in combination. At the hypnotic end-point, interactions were analysed by fitting...

journal_title：British journal of anaesthesia

authors： Short TG,Plummer JL,Chui PT

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:A pulmonary hypertensive crisis (PHC) can be a life-threatening condition. We established a PHC model by exposing rats with monocrotaline (MCT)-induced pulmonary hypertension to acute hypoxia, and investigated the effects of vasopressin, phenylephrine, and norepinephrine on the PHC. METHODS:Four weeks after...

journal_title：British journal of anaesthesia

authors： Sugawara Y,Mizuno Y,Oku S,Goto T

更新日期：2019-04-01 00:00:00

abstract：:The sedation of 50 children aged 6 months to 9 years who had undergone open heart surgery was studied. During artificial ventilation a midazolam infusion was used in conjunction with the administration of morphine (and tubocurarine). Sedation for patients breathing spontaneously with positive airway pressure was conti...

journal_title：British journal of anaesthesia

authors： Booker PD,Beechey A,Lloyd-Thomas AR

更新日期：1986-10-01 00:00:00

abstract：:Two patients are described in whom failure of the Pollard endotracheal tube produced complete respiratory obstruction. Comparisons are made of external diameters, resistance to gas flow and resistance to compression between Pollard tubes and several conventional tubes. It is concluded that the Pollard tube is not sati...

journal_title：British journal of anaesthesia

authors： Child DA,Ali MM

更新日期：1977-02-01 00:00:00

abstract：:We studied 52 adults undergoing elective craniotomy, allocated randomly to one of three opioid treatments: alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 until dural closure (group Alf.); alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 for 2 h, then remifentanil 0.25 microgra...

journal_title：British journal of anaesthesia

authors： Sneyd JR,Whaley A,Dimpel HL,Andrews CJ

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Increasing numbers of older patients prescribed clopidogrel are presenting for urgent hip fracture surgery. Best practice for the management of clopidogrel therapy is unknown, although delays to surgery are associated with increased mortality. We investigated the influence of perioperative management of clop...

journal_title：British journal of anaesthesia

authors： Collyer TC,Reynolds HC,Truyens E,Kilshaw L,Corcoran T

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Growing evidences indicate that inhalational anaesthetics can enhance the growth and malignant potential of tumour cells and may affect tumour recurrence after surgery. Tumour stem cells play a vital role in tumour recurrence. This study investigates the effect of sevoflurane on glioma stem cells (GSCs) in v...

journal_title：British journal of anaesthesia

authors： Shi QY,Zhang SJ,Liu L,Chen QS,Yu LN,Zhang FJ,Yan M

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The properties of methadone suggest a potential advantage for epidural over i.v. administration for pain relief, but little supportive evidence exists. METHODS:To investigate the pharmacokinetic and the pharmacodynamic properties of epidural and i.v. methadone, four doses of methadone (0.1, 0.25, 0.5, and 0...

journal_title：British journal of anaesthesia

authors： Haroutiunian S,Kagan L,Yifrach-Damari I,Davidson E,Ratz Y,Hoffman A

更新日期：2014-01-01 00:00:00

abstract：:The influence of halothane was studied on train-of-four fade during spontaneous recovery from neuromuscular block produced by atracurium in 42 children undergoing routine surgical procedures under general anaesthesia. The ulnar nerve was stimulated at the wrist, and compound electromyographic responses were recorded f...

journal_title：British journal of anaesthesia

authors： Woloszczuk-Gebicka B

更新日期：1990-10-01 00:00:00

abstract：:The neuromuscular and cardiovascular effects of atracurium were compared during nitrous oxide-isoflurane and nitrous oxide-fentanyl anaesthesia in healthy surgical patients. The dose-response curve was shifted significantly to the left during nitrous oxide-isoflurane anaesthesia (ED50 0.068 mg kg-1) as compared with n...

journal_title：British journal of anaesthesia

authors： Rupp SM,Fahey MR,Miller RD

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Investigators planning dose-response studies of neuromuscular blockers have rarely used a priori power analysis to determine the minimal sample size their protocols require. Institutional Review Boards and peer-reviewed journals now generally ask for this information. This study outlines a proposed method fo...

journal_title：British journal of anaesthesia

authors： Kopman AF,Lien CA,Naguib M

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Pulse pressure variation (PPV) and stroke volume variation (SVV) are robust indicators of fluid responsiveness in mechanically ventilated supine patients. The aim of the study was to evaluate the ability of PPV and SVV to predict fluid responsiveness in mechanically ventilated patients in the prone position ...

journal_title：British journal of anaesthesia

authors： Biais M,Bernard O,Ha JC,Degryse C,Sztark F

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Midlatency auditory evoked potentials (MLAEP) are a promising tool for monitoring suppression of sensory processing during anaesthesia and might help to avoid awareness. MLAEP in children are different to those in adults and the exact changes during general anaesthesia are unknown. METHODS:In 49 children of...

journal_title：British journal of anaesthesia

authors： Daunderer M,Feuerecker MS,Scheller B,Pape NB,Schwender D,Kuhnle GE

更新日期：2007-12-01 00:00:00

abstract：:We randomized women having elective Caesarean section to receive either no preload (control group, n=33) or 4% gelatin solution (Gelofusine) 15 ml kg(-1) (colloid group, n=35) i.v. before spinal anaesthesia. Intravenous metaraminol was titrated at 0.25-0.75 mg min(-1) to maintain systolic arterial pressure (SAP) in th...

journal_title：British journal of anaesthesia

authors： Ngan Kee WD,Khaw KS,Lee BB,Ng FF,Wong MM

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:There has been increasing use of invasive techniques, such as extracorporeal organ support, in intensive care units (ICU), and declining autopsy rates. Thus, new measures are needed to maintain high-quality standards. We investigated the potential of computed tomography (CT)-based virtual autopsy to substitu...

journal_title：British journal of anaesthesia

authors： Wichmann D,Heinemann A,Zähler S,Vogel H,Höpker W,Püschel K,Kluge S

更新日期：2018-06-01 00:00:00