Neuromuscular and cardiovascular effects of atracurium during nitrous oxide-fentanyl and nitrous oxide-isoflurane anaesthesia.

abstract：:We have investigated the effect of a bolus injection of atracurium 0.6 mg kg-1 on the cardiovascular system in 16 patients undergoing aortocoronary bypass surgery. H1- and H2-receptor antagonists were administered to eight patients before the neuromuscular blocker. A standard anaesthetic was used comprising fentanyl, ...

journal_title：British journal of anaesthesia

authors： Adt M,Baumert JH,Reimann HJ

更新日期：1992-02-01 00:00:00

abstract：:The face-grafting techniques are innovative and highly complex, requiring well-defined organization of all the teams involved. Subsequent to the first report in France in 2005, there have been 17 facial allograft transplantations performed worldwide. We describe anaesthesia and postoperative management, and the proble...

journal_title：British journal of anaesthesia

authors： Sedaghati-nia A,Gilton A,Liger C,Binhas M,Cook F,Ait-Mammar B,Scherrer E,Hivelin M,Lantieri L,Marty J,Plaud B

更新日期：2013-10-01 00:00:00

abstract：:Experiments were performed on rats using two analgesimetric tests (tail-flick; hot-plate) before and after injection i.v. of graded doses of aprotinin (12.5, 25.0 and 50 KIU g-1). A dose-related analgesic effect was noted with both tests. Prior administration of naloxone 0.001 mg g-1 i.p. inhibited the analgesic actio...

journal_title：British journal of anaesthesia

authors： Novelli GP,Pieraccioli E,Peduto VA,Festimanni F

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:None of the currently available hypnosis monitoring systems have evaluated balanced xenon anaesthesia. We investigated the performance of the bispectral index (BIS) and the composite A-line autoregressive index (cAAI) while comparing balanced xenon with sevoflurane anaesthesia. METHODS:Sixty patients underg...

journal_title：British journal of anaesthesia

authors： Fahlenkamp AV,Peters D,Biener IA,Billoet C,Apfel CC,Rossaint R,Coburn M

更新日期：2010-09-01 00:00:00

abstract：:We studied the size 4 laryngeal mask airway (LMA) to test the hypothesis that oropharyngeal leak pressure and fibreoptic position improves with increasing cuff volume. After LMA insertion, 50 anaesthetized adult patients had the cuff inflated in 5-ml increments to 40 ml. Oropharyngeal leak pressure was optimal at 15 m...

journal_title：British journal of anaesthesia

authors： Keller C,Pühringer F,Brimacombe JR

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Isoflurane has been reported to induce caspase-3 activation, which may induce neurotoxicity and contribute to the pathogenesis of Alzheimer's disease. However, the underlying mechanism is largely unknown, especially whether or not isoflurane can induce ryanodine receptors (RyRs)-associated endoplasmic reticu...

journal_title：British journal of anaesthesia

authors： Wang H,Dong Y,Zhang J,Xu Z,Wang G,Swain CA,Zhang Y,Xie Z

更新日期：2014-10-01 00:00:00

abstract：:We present a new pattern of nerve stimulation--double burst stimulation (DBS)--to detect residual neuromuscular block manually. The DBS consists of two short lasting, 50-Hz tetanic stimuli or bursts separated by a 750-ms interval. The response to this pattern of stimulation is two single separated muscle contractions ...

journal_title：British journal of anaesthesia

authors： Engbaek J,Ostergaard D,Viby-Mogensen J

更新日期：1989-03-01 00:00:00

abstract：:We studied the elimination rate of nitrous oxide in 36 patients undergoing orthopaedic surgery. They were allocated randomly to one of six groups which differed in time of nitrous oxide exposure and mode of ventilation. In order to simulate recovery conditions, nitrous oxide administration was discontinued after 30, 6...

journal_title：British journal of anaesthesia

authors： Einarsson S,Stenqvist O,Bengtsson A,Houltz E,Bengtson JP

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Multiple cognitive and psychiatric disorders are associated with an increased tonic inhibitory conductance that is generated by α5 subunit-containing γ-aminobutyric acid type A (α5 GABAA) receptors. Negative allosteric modulators that inhibit α5 GABAA receptors (α5-NAMs) are being developed as treatments for...

journal_title：British journal of anaesthesia

authors： Manzo MA,Wang DS,Li WW,Pinguelo A,Popa MO,Khodaei S,Atack JR,Ross RA,Orser BA

更新日期：2020-12-30 00:00:00

abstract：:In 1849 John Snow, already the leading anaesthetic practitioner and innovator of his day, made a historic contribution to the epidemiology of infectious disease by his famous study of the distribution of cholera around the area of Broad Street in London. We report on our experience as anaesthetists in a field hospital...

journal_title：British journal of anaesthesia

authors： Ginosar Y,Shapira SC

更新日期：1995-12-01 00:00:00

abstract：Background:There is growing evidence that beta-blockade may reduce mortality in selected patients with sepsis. However, it is unclear if a pre-existing, chronic oral beta-blocker therapy should be continued or discontinued during the acute phase of severe sepsis and septic shock. Methods:The present secondary analysis...

journal_title：British journal of anaesthesia

authors： Fuchs C,Wauschkuhn S,Scheer C,Vollmer M,Meissner K,Kuhn SO,Hahnenkamp K,Morelli A,Gründling M,Rehberg S

更新日期：2017-10-01 00:00:00

abstract：:Intraoperative awareness, with or without recall, continues to be a topic of clinical significance and neurobiological interest. In this article, we review evidence pertaining to the incidence, sequelae, and prevention of intraoperative awareness. We also assess which aspects of the complication are well understood (i...

journal_title：British journal of anaesthesia

authors： Mashour GA,Avidan MS

更新日期：2015-07-01 00:00:00

abstract：:In this study, we simultaneously evaluated the spasmolytic effects of prostaglandin E1 (PGE1) on serotonin-induced bronchoconstriction and pulmonary hypertension. Eleven mongrel dogs (8-12 kg) anaesthetized with pentobarbital were assigned to two groups: saline (n = 4) and PGE1 (n = 7). Bronchoconstriction and pulmona...

journal_title：British journal of anaesthesia

authors： Hashimoto Y,Hirota K,Yoshioka H,Hashiba E,Kudo T,Ishihara H,Matsuki A

更新日期：2000-09-01 00:00:00

abstract：:Forty patients who had undergone coronary artery graft surgery and who required vasodilator therapy for postoperative hypertension were given infusions of either alfentanil or morphine together with bolus doses of midazolam for sedation and analgesia while ventilation was controlled artificially. Sodium nitroprusside ...

journal_title：British journal of anaesthesia

authors： McMenemin IM,Church JA,Kenny GN

更新日期：1988-12-01 00:00:00

abstract：:We have measured the partial pressure of isoflurane simultaneously in inspired gas (PIiso), end-expired gas (PE'iso), mixed-expired gas (PEiso), arterial (Paiso) and mixed venous blood (Pviso) in six patients (aged 57-79 yr) anaesthetized with nitrous oxide, oxygen and isoflurane before surgery and after PE'iso had be...

journal_title：British journal of anaesthesia

authors： Landon MJ,Matson AM,Royston BD,Hewlett AM,White DC,Nunn JF

更新日期：1993-06-01 00:00:00

abstract：:Intragastric pressure was measured in 20 patients before, and immediately after, the induction of anaesthesia with thiopentone. Intragastric pressure decreased in patients whose weights were the same as or less than expected, and increased in five of seven patients whose weights were greater than expected (P = 0.0013)...

journal_title：British journal of anaesthesia

authors： Drummond GB,Park GR

更新日期：1984-08-01 00:00:00

abstract：:The fresh gas flow rate necessary to prevent rebreathing in T-piece anaesthesia is well established at twice total ventilation. The minimum reservoir volume to avoid air dilution of anaesthetic gases in the alveolus at this flow rate is, however, undecided. A lung model was constructed to represent spontaneous respira...

journal_title：British journal of anaesthesia

authors： Naunton A

更新日期：1985-08-01 00:00:00

abstract：:Using human nasal cytological brushings, we have investigated the effects of morphine on ciliary function by measurement of cilia beat frequency in vitro, and we have also determined opioid receptor binding in these specimens. We obtained ciliated samples from seven volunteers, and measured cilia beat frequency using ...

journal_title：British journal of anaesthesia

authors： Selwyn DA,Raphael JH,Lambert DG,Langton JA

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Midlatency auditory evoked potentials (MLAEP) are a promising tool for monitoring suppression of sensory processing during anaesthesia and might help to avoid awareness. MLAEP in children are different to those in adults and the exact changes during general anaesthesia are unknown. METHODS:In 49 children of...

journal_title：British journal of anaesthesia

authors： Daunderer M,Feuerecker MS,Scheller B,Pape NB,Schwender D,Kuhnle GE

更新日期：2007-12-01 00:00:00

abstract：:Sickle cell disease is a congenital haemoglobinopathy with a high incidence of perioperative complications. Traditional anaesthetic management, based largely on extrapolation from biochemical models, has emphasized avoidance of red cell sickling to prevent exacerbations of the disease. This historical review outlines ...

journal_title：British journal of anaesthesia

authors： Firth PG

更新日期：2005-09-01 00:00:00

abstract：:We have studied the tone of the lower oesophageal sphincter (LOS) in 40 adults undergoing routine body surface surgery and allocated randomly to receive anaesthesia either by face mask and Guedel airway or by laryngeal mask airway. In the laryngeal mask group there was a mean (SEM) decrease in barrier pressure (LOS mi...

journal_title：British journal of anaesthesia

authors： Rabey PG,Murphy PJ,Langton JA,Barker P,Rowbotham DJ

更新日期：1992-10-01 00:00:00

abstract：:Midazolam 0.3 mg kg-1 was given as a single dose to three groups of children undergoing cardiac surgery to determine its pharmacokinetic profile in this situation. The first group, undergoing closed heart surgery, received the midazolam during the operation. The other groups underwent cardiopulmonary bypass (CPB) with...

journal_title：British journal of anaesthesia

authors： Mathews HM,Carson IW,Lyons SM,Orr IA,Collier PS,Howard PJ,Dundee JW

更新日期：1988-09-01 00:00:00

abstract：:Relative humidity of air produced by simple compressors used to drive ventilators was measured at different working pressures. At normal working pressures, a relative humidity of 100% was found and condensation occurred, mainly at the high pressure air/oxygen mixer valve. This resulted in blockages and loss of accurac...

journal_title：British journal of anaesthesia

authors： Conely JI,Railton R,MacKenzie AI

更新日期：1981-05-01 00:00:00

abstract：Background:Checklists can reduce medical errors. However, the effectiveness of checklists is hampered by lack of acceptance and compliance. Recently, a new type of checklist with dynamic properties has been created to provide more specific checklist items for each individual patient. Our purpose in this simulation-base...

journal_title：British journal of anaesthesia

authors： De Bie AJR,Nan S,Vermeulen LRE,Van Gorp PME,Bouwman RA,Bindels AJGH,Korsten HHM

更新日期：2017-08-01 00:00:00

abstract：:Cytokine synthesis and release is an essential component of the innate immune system, but inappropriate, excessive production results in a generalized systemic inflammatory response which damages distant organs. Recent research has identified an immunomodulatory function of the vagus nerve whereby activation of the ef...

journal_title：British journal of anaesthesia

authors： Johnston GR,Webster NR

更新日期：2009-04-01 00:00:00

abstract：:Lung function and clinical evidence of muscle weakness were assessed in 12 ASA I patients who received vecuronium 0.01 mg kg-1 pretreatment as a part of their anaesthetic management, before and 3 min after pretreatment. Most patients demonstrated ptosis and diplopia, while five of the 12 were unable to raise the head ...

journal_title：British journal of anaesthesia

authors： Mahajan RP,Laverty J

更新日期：1992-09-01 00:00:00

abstract：:The identification of a serum marker to assist in the diagnosis of cerebral injury after cardiac surgery is potentially useful. S100 protein is an early marker of cerebral damage. It is released after cardiac surgery performed under cardiopulmonary bypass (CPB). Its level is correlated with the duration of CPB, deep c...

journal_title：British journal of anaesthesia

authors： Ali MS,Harmer M,Vaughan R

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The minimum alveolar concentration (MAC) is a traditional index of the hypnotic potency of an inhalational anaesthetic. To investigate the anaesthetic as well as the unwanted effects of xenon (Xe) in a swine model, it is useful to know MAC(Xe). METHODS:The study was performed using ten swine (weight 27.8-35...

journal_title：British journal of anaesthesia

authors： Hecker KE,Horn N,Baumert JH,Reyle-Hahn SM,Heussen N,Rossaint R

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:One major risk factor of the sitting position for neurosurgery is air embolism, especially in patients with persistent foramen ovale (PFO). The first aim of this prospective study was to evaluate a bedside method for detecting PFO using transcranial Doppler sonography (TCD) with contrast medium. A second aim...

journal_title：British journal of anaesthesia

authors： Engelhardt M,Folkers W,Brenke C,Scholz M,Harders A,Fidorra H,Schmieder K

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:High-dose glucocorticoid may reduce postsurgical pain and improve recovery. We hypothesized that 125 mg methylprednisolone (MP) would reduce time to meet functional discharge criteria after total hip arthroplasty (THA). METHODS:Forty-eight patients undergoing unilateral THA under spinal anaesthesia were con...

journal_title：British journal of anaesthesia

authors： Lunn TH,Andersen LØ,Kristensen BB,Husted H,Gaarn-Larsen L,Bandholm T,Ladelund S,Kehlet H

更新日期：2013-01-01 00:00:00