Abstract：
:In 1849 John Snow, already the leading anaesthetic practitioner and innovator of his day, made a historic contribution to the epidemiology of infectious disease by his famous study of the distribution of cholera around the area of Broad Street in London. We report on our experience as anaesthetists in a field hospital, dispatched as part of the international rescue effort to Goma, Zaire, to help combat the effects of cholera among the Rwandan refugees. :The experience of a medical team dispatched to field hospitals in Goma, Zaire, as part of an international rescue effort to combat the effects of a cholera epidemic among Rwandan refugees illustrates the importance of planning and collaboration. The mission included 5 pediatricians, 4 general practitioners, 2 anesthetists, 2 general surgeons, and 1 orthopedic surgeon. The team's goal was to function as a walk-in clinic for sick and dying refugees and as a regional hospital providing laboratory, x-ray, and surgical facilities. Through a strategy of cooperation with primary care clinics, the team was able to prioritize the treatment of the sickest patients in need of intravenous therapy. Anesthetists had a prominent role in both performing major and central venous cannulations and instructing other physicians in the procedure. Surgery was confined to pregnancy-related procedures and trauma cases. In the 2 weeks of this mission, 1200 patients were treated, most of whom were in severe shock. Where possible, bolus spinal anesthesia was used to minimize the need for postoperative respiratory support. Recommended, in future missions, are baseline electrolyte measurements, a laryngeal mask airway, portable ventilators, and monitoring of end-tidal carbon dioxide.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Ginosar Y,Shapira SCdoi
10.1093/bja/75.6.810subject
Has Abstractpub_date
1995-12-01 00:00:00pages
810-6issue
6eissn
0007-0912issn
1471-6771pii
S0007-0912(17)44002-5journal_volume
75pub_type
杂志文章abstract：BACKGROUND:Tracheal tube tip and cuff positions of different cuffed paediatric tracheal tube brands in the trachea can vary with design. METHODS:Data from three clinical studies with measured tracheal lengths were pooled in a database including 422 children aged from birth to 16 yr. Dimensional data of seven cuffed pa...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2018.05.002
更新日期：2018-08-01 00:00:00
abstract：:We have assessed a prototype laryngeal mask airway (pLMA) in 50 anaesthetized children for ease of insertion, oropharyngeal leak pressures, gastric insufflation and fibreoptic position. The pLMA has a second smaller mask, which rests against the upper oesophageal sphincter, and a second cuff to increase the seal press...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/82.1.132
更新日期：1999-01-01 00:00:00
abstract：BACKGROUND:Tobacco use interventions in surgical patients who smoke could benefit both their short-term outcome and long-term health. Anaesthesiologists and surgeons can play key roles in delivering these interventions. This study determined the practices, attitudes, and beliefs of these physicians regarding tobacco us...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,多中心研究
doi：10.1093/bja/aem400
更新日期：2008-03-01 00:00:00
abstract：:Plasma diazepam concentrations were determined following oral, i.m. and i.v. administration to a group of pregnant women with pre-eclampsia and a group of normal pregnant women. Diazepam concentrations were greater following oral as compared with i.m. administration in the control group, who received a single 5-mg dos...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/48.11.1091
更新日期：1976-11-01 00:00:00
abstract：:Sleep disordered breathing is a common problem affecting all age groups, particularly in association with certain other medical conditions and syndromes. The pathological consequences of the disorder may be severe, with significant implications for the perioperative management of sufferers. Research into the effects o...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/86.2.254
更新日期：2001-02-01 00:00:00
abstract：:Following a paravertebral surgical incision, mature, female rats under ether anaesthesia were exposed to either 3% nitrous oxide, continuously for 48 h, or 50% nitrous oxide, 4 h each day for 7 days. For each exposure group, a similar number of rats was exposed to atmospheres containing no nitrous oxide. Wound healing...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/57.6.621
更新日期：1985-06-01 00:00:00
abstract：:The effects of the i.v. infusion of insulin, 70 mu. kg-1h-1 for the first 60 min and 35 mu. kg-1h-1 subsequently, on the metabolic and endocrine responses to gynaecological surgery were investigated. In comparison with a control group of patients, the insulin infusion caused a marked decrease in circulating glucose, n...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/55.10.939
更新日期：1983-10-01 00:00:00
abstract：:The kinetics of morphine were studied during balanced anaesthesia in 10 patients undergoing lower abdominal or body surface surgery, and compared with those obtained in nine awake patients receiving morphine i.v. for the relief of chronic non-cancer pain. All patients received morphine sulfphate pentahydrate 10 mg i.v...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/62.1.22
更新日期：1989-01-01 00:00:00
abstract：:Atropine and glycopyrrolate were compared in a mixture with neostigmine for reversal of neuromuscular blockade in patients undergoing open heart surgery. In patients not receiving beta-blocking drugs, glycopyrrolate was shown to possess advantages over atropine in terms of a lower initial increase in heart rate, bette...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/57.2.184
更新日期：1985-02-01 00:00:00
abstract：:Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system st...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/57.11.1049
更新日期：1985-11-01 00:00:00
abstract：BACKGROUND:Double-lumen tubes (DLTs) are frequently used to establish one-lung ventilation (OLV). Their correct placement is crucial. We hypothesized that electrical impedance tomography (EIT) reliably displays distribution of ventilation between left and right lung and may thus be used to verify correct DLT placement ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aen166
更新日期：2008-09-01 00:00:00
abstract：:The pharmacokinetics of edrophonium were determined in patients anaesthetized with nitrous oxide and halothane undergoing kidney transplant nephrectomy (n=6) or transplantation of a live related donor kidney (n = 6). Serum concentrations of edrophonium were assayed by high pressure liquid chromatography and pharmacoki...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/53.12.1311
更新日期：1981-12-01 00:00:00
abstract：:We have evaluated the clinical utility and blood propofol concentrations produced with two different infusion regimens for propofol, given to supplement 67% nitrous oxide-morphine anaesthesia. Patients received a standardized three-step infusion of propofol based either on body weight (weight-corrected group) or on a ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/74.4.362
更新日期：1995-04-01 00:00:00
abstract：BACKGROUND:Chronic treatment with renin-angiotensin system (RAS) antagonists frequently causes deleterious hypotension during anaesthesia. We compared the effects of angiotensin II receptor antagonists (ARA) and angiotensin-converting enzyme inhibitors (ACEI) on neurohormonal levels and haemodynamics during cardiopulmo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/ael268
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:The therapeutic potential of cardiac μ-opioid receptors in ischaemia-reperfusion (I/R) injury during opioid-modulating diseases, such as heart failure, is unknown. We aimed to explore the changes of cardiac μ-opioid receptor expression during heart failure, and its role in opioid-induced cardioprotection. M...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2017.11.110
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Echocardiography has been shown to positively impact on the management of the critically ill patient. However, many published studies have a significant bias towards inclusion of cardiothoracic patients. We present an audit of the impact of echocardiography on the management of patients in a district general...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aen378
更新日期：2009-03-01 00:00:00
abstract：:Isolated, cultured rat pancreatic islets of Langerhans were incubated in medium containing glucose 2 or 20 mmol litre-1 and with glucose supplemented with midazolam 10, 100 or 1000 ng ml-1. Glucose 20 mmol litre-1 with the addition of noradrenaline 10 mumol litre-1 was used as a control. In contrast with noradrenaline...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/70.2.221
更新日期：1993-02-01 00:00:00
abstract：:We studied psychomotor performance in 10 healthy volunteers during recovery after a target-controlled infusion of propofol. Choice reaction time, dual task tracking with secondary reaction time and a within-list recognition task were assessed at target blood propofol concentrations of 0.8, 0.4 and 0.2 microgram ml-1. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/85.3.396
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND:Owing to complexities of measuring dead space, ventilatory failure is difficult to quantify in critical care. A simple, novel index called ventilatory ratio (VR) can quantify ventilatory efficiency at the bedside. The study objectives were to evaluate physiological properties of VR and examine its clinical a...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aet283
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Inconsistent and poorly coordinated systems of tracheostomy care commonly result in frustrations, delays, and harm. Quality improvement strategies described by exemplar hospitals of the Global Tracheostomy Collaborative have potential to mitigate such problems. This 3 yr guided implementation programme inves...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bja.2020.04.064
更新日期：2020-07-01 00:00:00
abstract：:Blood transfusion saves many lives but carries significant risk of injury. Currently, red blood cell (RBC) concentrates can be stored up to 42 days. Concerns have recently been raised about the safety and efficacy of transfusing stored RBCs. Refrigerated storage results in a 'storage lesion' that is reflected by metab...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aet405
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Single preoperative gabapentinoid (gabapentin and pregabalin) administration has been associated with respiratory depression during Phase I anaesthesia recovery. In this study, we assess for associations between chronic (home) use and perioperative administration (preoperative and postoperative) of gabapenti...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2017.11.113
更新日期：2018-04-01 00:00:00
abstract：:We calculated oxygen consumption by the reverse Fick principle (cVO2) using cardiac output measured with a new technique of continuous thermal dilution and compared these values with measurements made at the same time using a gas exchange method (mVO2). We studied nine patients in a stable condition after cardiac surg...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/75.6.719
更新日期：1995-12-01 00:00:00
abstract：BACKGROUND:Mechanosensory thalamocortical relay neurones (TCNs) receive glutamatergic excitatory input and are subjected to gamma-aminobutyric acid (GABA)Aergic inhibitory input. This study assessed the effects of an increase in concentration of isoflurane on thalamic excitatory and inhibitory mechanisms. METHODS:TCNs...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aef170
更新日期：2002-08-01 00:00:00
abstract：Background:Cognitive aids improve the technical performance of individuals and teams dealing with high-stakes crises. Hand-held electronic cognitive aids have rarely been investigated. A randomized controlled trial was conducted to investigate the effects of a smartphone application, named MAX (for Medical Assistance e...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aex256
更新日期：2017-11-01 00:00:00
abstract：:The fate of gallamine triethiodide has been investigated in patients undergoing cholecystectomy with choledochostomy (group I), pelvic operations (group II) and orthopaedic operations (group III). Following a single i.v. injection of gallamine 2.5 mg kg(-1) the disappearance of the drug from the serum occurred in thre...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/50.4.345
更新日期：1978-04-01 00:00:00
abstract：BACKGROUND:Preoperative anaemia affects one third of patients undergoing cardiac surgery and is associated with increased mortality and morbidity. Although it is recommended that perioperative teams should identify and treat patients with preoperative anaemia before surgery, introducing new treatment protocols can be c...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bja.2019.11.023
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:There are no studies comparing local anaesthetic requirements for obese and normal parturients. Obesity has been associated with a higher incidence of Caesarean section and higher levels of epidural block have also been found in obese obstetric patients, suggesting they may require less local anaesthetic. Th...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aei284
更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:Patients with hip fractures are usually frail and elderly with a 30-day mortality in excess of 10% in European series. Perioperative morbidity is often multifactorial in nature, and unimodal interventions will not necessarily decrease mortality. The purpose of this prospective study was to analyse causes o...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aei010
更新日期：2005-01-01 00:00:00
abstract：:We have evaluated the level of state and trait anxiety, neuroticism, extroversion and coping style as predictors of the effectiveness of patient-controlled analgesia (PCA) in 110 patients undergoing total abdominal hysterectomy. After operation patients were allocated to receive pain control with either PCA or i.m. in...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/74.3.271
更新日期：1995-03-01 00:00:00
