Evaluation of bispectral index and auditory evoked potentials for hypnotic depth monitoring during balanced xenon anaesthesia compared with sevoflurane.

Abstract:

BACKGROUND:None of the currently available hypnosis monitoring systems have evaluated balanced xenon anaesthesia. We investigated the performance of the bispectral index (BIS) and the composite A-line autoregressive index (cAAI) while comparing balanced xenon with sevoflurane anaesthesia. METHODS:Sixty patients undergoing elective abdominal surgery participated in this registered double-blinded, controlled trial and-after written informed consent-were randomly assigned to one of the study groups (xenon, n=30; sevoflurane, n=30). After induction, general anaesthesia was maintained with xenon 60% or sevoflurane 2.0% in 30% O2. Remifentanil was titrated to clinical needs. BIS and cAAI values were recorded electronically and blinded to the performing physician. Emergence from anaesthesia was evaluated and during 12 h follow-up, patients were questioned twice for signs of recalls. RESULTS:During induction and maintenance of anaesthesia, BIS values in the xenon group were comparable with sevoflurane anaesthesia and within the recommended range. Although the cAAI remained stable in the sevoflurane group, values increased during balanced xenon anaesthesia and exceeded the recommended upper limit after 65 min. Emergence from xenon anaesthesia was significantly faster than from sevoflurane (eye opening at 3.8 vs 10.3 min, P<0.001), and BIS values were concordant with the washout of both anaesthetics. No incident of recall was reported. CONCLUSIONS:During surgery, xenon/remifentanil anaesthesia can be monitored using BIS and cAAI. However, cAAI values changed after about 1 h of anaesthesia. Further studies will be needed to address the question whether auditory signal processing is altered during extended xenon exposure.

journal_name

Br J Anaesth

authors

Fahlenkamp AV,Peters D,Biener IA,Billoet C,Apfel CC,Rossaint R,Coburn M

doi

10.1093/bja/aeq163

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

334-41

issue

3

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)33508-0

journal_volume

105

pub_type

杂志文章,随机对照试验
  • Differential effects of isoflurane on excitatory and inhibitory synaptic inputs to thalamic neurones in vivo.

    abstract:BACKGROUND:Mechanosensory thalamocortical relay neurones (TCNs) receive glutamatergic excitatory input and are subjected to gamma-aminobutyric acid (GABA)Aergic inhibitory input. This study assessed the effects of an increase in concentration of isoflurane on thalamic excitatory and inhibitory mechanisms. METHODS:TCNs...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aef170

    authors: Detsch O,Kochs E,Siemers M,Bromm B,Vahle-Hinz C

    更新日期:2002-08-01 00:00:00

  • New drugs and technologies, intravenous anaesthesia is on the move (again).

    abstract::Although well established in clinical practice, both propofol and midazolam have limitations. New hypnotics with different and potentially superior pharmacokinetics and pharmacodynamics are under development. These include the benzodiazepine receptor agonists CNS7056 and JM-1232 (-), the etomidate-based methoxycarbony...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aeq190

    authors: Sneyd JR,Rigby-Jones AE

    更新日期:2010-09-01 00:00:00

  • Nitrous oxide antagonizes CNS stimulation by laudanosine in mice.

    abstract::We have investigated whether nitrous oxide antagonizes or augments the CNS stimulant action of laudanosine in mice by comparing the mean convulsive doses (CD50 (SE] of a control group and those following pretreatment with 65% nitrous oxide in oxygen for 20 and 180 min. Nitrous oxide significantly increased CD50 from 4...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/65.5.704

    authors: Avramov MN,Mori K

    更新日期:1990-11-01 00:00:00

  • Placental blood flow during caesarean section under lumbar extradural analgesia.

    abstract::The effect on intervillous blood flow of lumbar extradural analgesia for Caesarean section was studied in nine healthy women using xenon-133. Extradural anaesthesia was performed with lignocaine 1 1/2% 16--20 ml with adrenaline 5 microgram ml-1. Impairment of placental blood flow during the block was observed in seven...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/50.3.275

    authors: Jouppila R,Jouppila P,Kuikka J,Hollmén A

    更新日期:1978-03-01 00:00:00

  • Antinociceptive effect of intrathecal ginsenosides through alpha-2 adrenoceptors in the formalin test of rats.

    abstract:BACKGROUND:We defined the nature of the pharmacological interaction after intrathecal co-administration of ginsenosides with clonidine, and clarified the contribution of the α-2 adrenoceptors on the effect of ginsenosides. METHODS:Pain was evoked by injection of a formalin solution (5%, 50 μl) into the hindpaw of male...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeq367

    authors: Yoon MH,Huang LJ,Choi JI,Lee HG,Kim WM,Kim CM

    更新日期:2011-03-01 00:00:00

  • A multicentre comparison of the costs of anaesthesia with sevoflurane or propofol.

    abstract::Day-case anaesthesia requires rapidly eliminated anaesthetics which are relatively expensive. This multinational, multicentre European study assessed the relative costs of propofol or sevoflurane anaesthesia in 211 patients. Anaesthesia was induced and maintained with propofol in group 1, with propofol and sevoflurane...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/bja/83.4.564

    authors: Smith I,Terhoeve PA,Hennart D,Feiss P,Harmer M,Pourriat JL,Johnson IA

    更新日期:1999-10-01 00:00:00

  • Pharmacology of an emulsion formulation of ICI 35 868.

    abstract::Studies with an emulsion formulation of ICI 35 868 (2,6- diisopropylphenol ) indicate that this new formulation has anaesthetic properties in rats and mice, and haemodynamic effects in the mini-pig which are similar to those of the previously available Cremophor formulation. Administration of the emulsion formulation ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/56.6.617

    authors: Glen JB,Hunter SC

    更新日期:1984-06-01 00:00:00

  • Effect of segmental extradural analgesia on placental blood flow during normal labour.

    abstract::Placental blood flow was measured during the first stage of normal labour using a xenon-133 clearance technique before and after segmental extradural analgesia. Analgesia was produced with 0.5% plain bupivacaine in eight patients and with 0.5% bupivacaine--adrenaline in 10 patients. Segmental extradural analgesia with...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/50.6.563

    authors: Jouppila R,Jouppila P,Hollmén A,Kuikka J

    更新日期:1978-06-01 00:00:00

  • Neurosurgical operations with the patient in sitting position: analysis of risk factors using transcranial Doppler sonography.

    abstract:BACKGROUND:One major risk factor of the sitting position for neurosurgery is air embolism, especially in patients with persistent foramen ovale (PFO). The first aim of this prospective study was to evaluate a bedside method for detecting PFO using transcranial Doppler sonography (TCD) with contrast medium. A second aim...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/ael015

    authors: Engelhardt M,Folkers W,Brenke C,Scholz M,Harders A,Fidorra H,Schmieder K

    更新日期:2006-04-01 00:00:00

  • Role of the massive transfusion protocol in the management of haemorrhagic shock.

    abstract::The concept of rapid delivery of multiple blood products to the bedside of a massively haemorrhaging patient seems to be a logical approach to the management of the massively bleeding patient. However, controversy exists in the use of fixed blood component ratios. Assessing the extent of the coagulopathy through point...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aeu379

    authors: Waters JH

    更新日期:2014-12-01 00:00:00

  • Rapidity and accuracy of tracheal intubation in a mannequin: comparison of the fibreoptic with the Bullard laryngoscope.

    abstract::Successful tracheal intubation with the flexible fibreoptic bronchoscope requires a certain amount of skill which is acquired by practice. It has been suggested that the new Bullard laryngoscope may be mastered more easily. To determine if learning was superior with a flexible fibreoptic or the Bullard device, the eas...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/65.2.268

    authors: Dyson A,Harris J,Bhatia K

    更新日期:1990-08-01 00:00:00

  • Nitrous oxide does not change the incidence of postoperative delirium or cognitive decline in elderly surgical patients.

    abstract:BACKGROUND:Postoperative delirium and cognitive decline are common in elderly surgical patients after non-cardiac surgery. Despite this prevalence and clinical importance, no specific aetiological factor has been identified for postoperative delirium and cognitive decline. In experimental setting in a rat model, nitrou...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/ael106

    authors: Leung JM,Sands LP,Vaurio LE,Wang Y

    更新日期:2006-06-01 00:00:00

  • What is really dangerous: anaemia or transfusion?

    abstract::Summary While complex physiological mechanisms exist to regulate and optimize tissue oxygenation under various conditions, clinical and experimental evidence indicates that anaemia, unchecked, is associated with organ injury and unfavourable outcomes. More data (especially from human studies) are needed to answer ques...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aer350

    authors: Shander A,Javidroozi M,Ozawa S,Hare GM

    更新日期:2011-12-01 00:00:00

  • Effects of sugammadex on incidence of postoperative residual neuromuscular blockade: a randomized, controlled study.

    abstract:BACKGROUND:This study aimed to investigate whether reversal of rocuronium-induced neuromuscular blockade with sugammadex reduced the incidence of residual blockade and facilitated operating room discharge readiness. METHODS:Adult patients undergoing abdominal surgery received rocuronium, followed by randomized allocat...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aev104

    authors: Brueckmann B,Sasaki N,Grobara P,Li MK,Woo T,de Bie J,Maktabi M,Lee J,Kwo J,Pino R,Sabouri AS,McGovern F,Staehr-Rye AK,Eikermann M

    更新日期:2015-11-01 00:00:00

  • Extradural analgesia in labour: complications of three techniques of administration.

    abstract::We have studied the complications associated with three techniques used to maintain extradural analgesia in labour: midwife top-up doses of 0.25% bupivacaine 10 ml, continuous infusion of 0.125% bupivacaine 10 ml h-1 and patient-controlled extradural analgesia (PCEA) with self-administered 3-ml bolus doses of 0.25% bu...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/73.5.619

    authors: Tan S,Reid J,Thorburn J

    更新日期:1994-11-01 00:00:00

  • Enhanced visual memory effect for negative versus positive emotional content is potentiated at sub-anaesthetic concentrations of thiopental.

    abstract:BACKGROUND:Emotional information has the ability to alter the formation and strength of a memory ('memory modulation'). Memory modulation by negative emotion is mediated by the amygdala. It is not known how gamma aminobutyric acid (GABA)ergic drugs affect the processes involved in memory modulation. This study investig...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/aeh211

    authors: Pryor KO,Veselis RA,Reinsel RA,Feshchenko VA

    更新日期:2004-09-01 00:00:00

  • Experience with spinal analgesia in a British obstetric unit.

    abstract::A series of 443 spinal anaesthetics is described. The procedures included operative vaginal delivery, removal of retained placenta and a miscellaneous group common to most obstetric units. Failure to provide effective relief of pain occurred in 5.2% of patients. There was one potentially serious complication, but with...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/51.6.531

    authors: Crawford JS

    更新日期:1979-06-01 00:00:00

  • Agreement between trainees and supervisors on first-year entrustable professional activities for anaesthesia training.

    abstract:BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2020.04.009

    authors: Marty AP,Schmelzer S,Thomasin RA,Braun J,Zalunardo MP,Spahn DR,Breckwoldt J

    更新日期:2020-07-01 00:00:00

  • Extradural morphine for the relief of pain following caesarean section.

    abstract::Thirty patients took part in a double-blind trial to compare morphine 10 mg i.m. with morphine 5 mg into the extradural space for pain relief following Caesarean section. With the extradural route the mean time to first analgesia was 7.95 h compared with 4.75 h for the i.m. route. The mean number of further doses of d...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/55.12.1201

    authors: Chambers WA,Mowbray A,Wilson J

    更新日期:1983-12-01 00:00:00

  • Association between postoperative mean arterial blood pressure and myocardial injury after noncardiac surgery.

    abstract:BACKGROUND:Myocardial injury after noncardiac surgery is common, although the exact pathophysiology is unknown. It is plausible that hypotension after surgery is relevant for the development of myocardial injury. The authors evaluated whether low mean arterial pressures (MAPs) after surgery are related to an increased ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2017.11.002

    authors: van Lier F,Wesdorp FHIM,Liem VGB,Potters JW,Grüne F,Boersma H,Stolker RJ,Hoeks SE

    更新日期:2018-01-01 00:00:00

  • Termination of supraventricular tachycardia by propofol.

    abstract::It is known that propofol can have effects on atrioventricular node conduction. We report a case where administration of propofol was associated with termination of supraventricular tachycardia. Although a similar phenomenon has been reported in children, this is the first such case in an adult. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:

    authors: Kannan S,Sherwood N

    更新日期:2002-06-01 00:00:00

  • Sex and oestrous cycle differences in visceromotor responses and vasopressin release in response to colonic distension in male and female rats anaesthetized with halothane.

    abstract::Visceromotor responses and vasopressin release before and after colonic visceral distension were compared between male (n=5 (n=4 for vasopressin)) and female rats and between females during the oestrous cycle (proestrus n=6, oestrus n=5, metestrus n=5, diestrus n=6) at a controlled depth of anaesthesia. Pre-stimulatio...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/85.6.907

    authors: Holdcroft A,Sapsed-Byrne S,Ma D,Hammal D,Forsling ML

    更新日期:2000-12-01 00:00:00

  • Tracheal tube pressure change during magnetic stimulation of the phrenic nerves as an indicator of diaphragm strength on the intensive care unit.

    abstract::Diaphragm strength can be assessed from twitch gastric (TwPgas), twitch oesophageal (TwPoes), and twitch transdiaphragmatic pressure (TwPdi) in response to phrenic nerve stimulation. This requires the passage of balloon catheters, which may be difficult. Changes in pressure measured at the mouth during phrenic nerve s...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/87.6.876

    authors: Mills GH,Ponte J,Hamnegard CH,Kyroussis D,Polkey MI,Moxham J,Green M

    更新日期:2001-12-01 00:00:00

  • Effect of clonidine on gastric emptying of liquids.

    abstract::We have investigated the effects of clonidine on gastric emptying of liquids in 30 patients. In a double-blind, randomized design, clonidine 150 micrograms, morphine 10 mg or saline in 1 ml was given i.m. One hour later, the patient drank a paracetamol solution (1.5 g in 50 ml water). Venous blood samples were obtaine...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/78.1.28

    authors: Asai T,McBeth C,Stewart JI,Williams J,Vaughan RS,Power I

    更新日期:1997-01-01 00:00:00

  • Fatal cardiac tamponade as a result of a peripherally inserted central venous catheter: a case report and review of the literature.

    abstract::We present a case of fatal cardiac tamponade that occurred in association with a peripherally inserted central catheter (PICC) inserted from the right antecubital fossa. Migration of the catheter from the right atrium within 24 h of insertion lead to the administration of a potassium-enriched sodium chloride solution ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aem181

    authors: Orme RM,McSwiney MM,Chamberlain-Webber RF

    更新日期:2007-09-01 00:00:00

  • Effects of halothane on respiratory mechanics and lung histopathology in normal rats.

    abstract::It is generally accepted that halothane reduces airway and tissue resistance in lungs with preexisting airway tone. However, under conditions of resting airway tone, pulmonary resistance remains unaltered. In this study, we have determined the effects of halothane on respiratory system, pulmonary and chest wall resist...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.bja.a013443

    authors: Reta GS,Riva JA,Piriz H,Medeiros AS,Rocco PR,Zin WA

    更新日期:2000-03-01 00:00:00

  • Nitrous oxide (N(2)O) reduces postoperative opioid-induced hyperalgesia after remifentanil-propofol anaesthesia in humans.

    abstract:BACKGROUND:The aim of this study was to test if intraoperative administration of N(2)O during propofol-remifentanil anaesthesia prevented the onset of postoperative opioid-induced hyperalgesia (OIH). METHODS:Fifty adult ASA I-II patients undergoing elective open septorhinoplasty under general anaesthesia were studied....

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer323

    authors: Echevarría G,Elgueta F,Fierro C,Bugedo D,Faba G,Iñiguez-Cuadra R,Muñoz HR,Cortínez LI

    更新日期:2011-12-01 00:00:00

  • Printed three-dimensional airway model assists planning of single-lung ventilation in a small child.

    abstract:BACKGROUND:Single-lung ventilation in infants and small children is challenging because suitable sizes of double-lumen cuffed tracheal tubes are not available. A 6-yr-old child required pulmonary saline washout for primary alveolar proteinosis, and therefore needed sequential single-lung ventilation in order to achieve...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aev305

    authors: Wilson CA,Arthurs OJ,Black AE,Schievano S,Hunt C,van Hoog S,Wallis C,Sury MR

    更新日期:2015-10-01 00:00:00

  • Halothane and propofol differentially affect electroencephalographic responses to noxious stimulation.

    abstract:BACKGROUND:Anaesthetics blunt neuronal responses to noxious stimulation, including effects on electroencephalographic (EEG) responses. It is unclear how anaesthetics differ in their ability to modulate noxious stimulation-evoked EEG activation. We investigated the actions of propofol and halothane on EEG responses to n...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aei208

    authors: Orth M,Barter L,Dominguez C,Atherley R,Carstens E,Antognini JF

    更新日期:2005-10-01 00:00:00

  • Intrathecal diamorphine compared with morphine for postoperative analgesia after caesarean section under spinal anaesthesia.

    abstract::A randomized, double-blind study of 40 women was performed to compare patient controlled anaesthesia (PCA) morphine requirements after spinal anaesthesia for elective Caesarean section. The women received 0.2 mg of either morphine or diamorphine mixed with 0.5% bupivacaine in 8% dextrose. There were no significant dif...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/81.2.135

    authors: Husaini SW,Russell IF

    更新日期:1998-08-01 00:00:00