Abstract：
BACKGROUND:It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the circadian distribution of sleep phases before and after surgery. METHODS:Eleven patients undergoing elective major abdominal surgery were included in the study. Continuous ambulatory polysomnographic monitoring was made 24 h before surgery and 36 h after surgery, thus including two nights after operation. Sleep was scored independently by two blinded observers and the recordings were reported as awake, light sleep (LS, stages I and II), slow wave sleep (SWS, stages III and IV), and REM sleep. RESULTS:There was significantly increased REM sleep (P=0.046), LS (P=0.020), and reduced time awake (P=0.016) in the postoperative daytime period compared with the preoperative daytime period. Five patients had REM sleep during the daytime after surgery. Three of these patients did not have REM sleep during the preceding postoperative night. There was significantly reduced night-time REM sleep for two nights after surgery compared with before surgery (P=0.001). CONCLUSIONS:Patients have significantly increased REM sleep, LS, and reduced time awake during the daytime period after surgery compared with before surgery. Disturbances in the circadian regulation of the sleep-wake cycle may be involved in the development of postoperative sleep disturbances.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Gögenur I,Wildschiøtz G,Rosenberg Jdoi
10.1093/bja/aem340subject
Has Abstractpub_date
2008-01-01 00:00:00pages
45-9issue
1eissn
0007-0912issn
1471-6771pii
S0007-0912(17)34593-2journal_volume
100pub_type
杂志文章abstract：:The serum vasopressin (S-AVP) concentration, serum sodium concentration and osmolality, central venous pressure and fluid balance were measured during 10-min periods in 32 patients undergoing transurethral resection of the prostate. Concentration of S-AVP was unaffected by uncomplicated resection; irrigant absorption ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/63.3.330
更新日期：1989-09-01 00:00:00
abstract：:We present a case of pulmonary thromboendarterectomy performed successfully in a patient with stomatocytosis. Stomatocytosis is a rare condition of abnormal erythrocyte morphology in which haemolysis and hyperkalaemia occur at cooler temperatures. A 35-yr-old male with stomatocytosis was referred for pulmonary thrombo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeg237
更新日期：2003-11-01 00:00:00
abstract：:We describe a 25 mg intrathecal morphine overdose during a combined spinal-epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aef286
更新日期：2002-12-01 00:00:00
abstract：:Advances in cannabis research have paralleled developments in opioid pharmacology whereby a psychoactive plant extract has elucidated novel endogenous signalling systems with therapeutic significance. Cannabinoids (CBs) are chemical compounds derived from cannabis. The major psychotropic CB delta-9-tetrahydrocannabino...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aen119
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which reflect spinal excitability, has been shown for propofol. We have assessed the concentration-dependent F-wave suppression by propofol and related it to th...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aei283
更新日期：2006-01-01 00:00:00
abstract：:The activity of a new i.v. anesthetic agent ICI 35 868, a compound unrelated to currently used barbiturate, eugenol or steroid agents, has been examined in a range of animal species. Some of the properties of ICI 35 868 resemble those of thiopentone in that it is a rapidly acting agent which produces anaesthesia of sh...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/52.8.731
更新日期：1980-08-01 00:00:00
abstract：BACKGROUND:The influence of changes in body position relevant to neuraxial blockade on the location of the spinal cord and related neural structures has not been fully quantified. Our aim was to determine the changes, if any, that occur in the location of the spinal cord tip [equivalent to the tip of the conus medullar...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aen295
更新日期：2008-12-01 00:00:00
abstract：:This is the report of a 55-yr-old female who developed severe myotonia and dystonia after general anaesthesia. Before starting on gabapentin therapy for a neuropathic pain condition, she had undergone numerous uneventful general anaesthetics. Since receiving treatment with gabapentin, she has experienced severe moveme...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aem130
更新日期：2007-08-01 00:00:00
abstract：:The neuromuscular blocking effect of repeated bolus administration of suxamethonium 1 mg/kg was observed in 10 healthy surgical patients under enflurane-nitrous oxide-oxygen anaesthesia. Tachyphylaxis and slow recovery of the thumb twitch occurred in close dose-relationships with transition of Phase I block to Phase I...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/48.2.91
更新日期：1976-02-01 00:00:00
abstract：BACKGROUND:The current prevalence of healthcare-associated infections (HCAIs) is a major public health concern. Patient contact in the operating theatre (OT) can contribute to HCAI via microbial contamination. The application of hand hygiene is effective in reducing infection rates. Limited data are available on adhere...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aer162
更新日期：2011-10-01 00:00:00
abstract：:Fires and explosions have occurred in the operating theatre for many years. Flammable inhalation anaesthetic agents were responsible for many incidents in the past, but these are no longer available in many countries. Other causes of fires and explosions still exist in the operating theatre and, from time to time, res...
journal_title：British journal of anaesthesia
pub_type： 历史文章,杂志文章
doi：10.1093/bja/73.6.847
更新日期：1994-12-01 00:00:00
abstract：BACKGROUND:We measured the effect of two weight adjusted i.v. doses (0.2 mg per 70 kg and 0.4 mg per 70 kg) of the potent opioid buprenorphine on analgesia and respiratory depression in healthy volunteers. The aim of the study was to compare buprenorphine's behaviour with respect to the occurrence of ceiling (or appare...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/ael051
更新日期：2006-05-01 00:00:00
abstract：:The sedation of 50 children aged 6 months to 9 years who had undergone open heart surgery was studied. During artificial ventilation a midazolam infusion was used in conjunction with the administration of morphine (and tubocurarine). Sedation for patients breathing spontaneously with positive airway pressure was conti...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/58.10.1104
更新日期：1986-10-01 00:00:00
abstract：BACKGROUND:Cyclic redistribution of air within the cuff during respiratory pressure changes creates a self-sealing mechanism which allows tracheal sealing, despite tracheal airway pressure being above baseline cuff inflation pressure. The aim of the present study was to investigate the effect of continuous automated cu...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aen355
更新日期：2009-02-01 00:00:00
abstract：:Two patients are described in whom failure of the Pollard endotracheal tube produced complete respiratory obstruction. Comparisons are made of external diameters, resistance to gas flow and resistance to compression between Pollard tubes and several conventional tubes. It is concluded that the Pollard tube is not sati...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/49.2.179
更新日期：1977-02-01 00:00:00
abstract：:The fate of gallamine triethiodide has been investigated in patients undergoing cholecystectomy with choledochostomy (group I), pelvic operations (group II) and orthopaedic operations (group III). Following a single i.v. injection of gallamine 2.5 mg kg(-1) the disappearance of the drug from the serum occurred in thre...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/50.4.345
更新日期：1978-04-01 00:00:00
abstract：:Chronic pain affects ∼20% of the European population and is commoner in women, older people, and with relative deprivation. Its management in the community remains generally unsatisfactory, partly because of lack of evidence for effective interventions. Epidemiological study of chronic pain, through an understanding o...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aet123
更新日期：2013-07-01 00:00:00
abstract：:Metoclopramide hastens emptying of the stomach. Since it may be given to patients before operation, the sedative and toxic effects of 10- and 20-mg does given i.m. were studied in patients and student volunteers. Saline and diazepam 10 mg were used as placebo and reference drugs. Neither dose of metoclopramide had as ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/46.7.509
更新日期：1974-07-01 00:00:00
abstract：BACKGROUND:The posterolateral and medial aspect of the arm is supplied by the axillary (AXN) and intercostobrachial nerves (ICBN), which are not anaesthetised by an axillary brachial plexus block (ABPB). Blockade of the AXN and the ICBN has been reported in the quadrangular space (QS) posteriorly or by serratus plane b...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2018.06.006
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:A recent study showed that the noble gas helium induces early myocardial preconditioning. Cyclooxygenase-2 (COX-2) has been shown to be an important mediator in the signal transduction of late preconditioning. In the present study, we investigated whether helium induces late preconditioning in a concentratio...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aep042
更新日期：2009-05-01 00:00:00
abstract：:A simple mathematical model of the chest wall was constructed so that during tidal breathing the relative volume contributions of the rib cage and abdomen/diaphragm could be measured in man, using four mercury-in-rubber strain gauges around the trunk. From the dimensions of the trunk and the change in circumference de...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/51.5.391
更新日期：1979-05-01 00:00:00
abstract：BACKGROUND:The AirWay Scope (AWS) is a fibreoptic device that allows for intubation without alignment of the oral, pharyngeal, and tracheal axes. It may be useful for patients with an unstable cervical-spine (C-spine) or when C-spine movement is undesirable. This study was conducted to fluoroscopically evaluate upper C...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aen207
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Dexmedetomidine has been proposed as a perineural local anaesthetic (LA) adjunct to prolong peripheral nerve block duration; however, results from our previous meta-analysis in the setting of brachial plexus block (BPB) did not support its use. Many additional randomized trials have since been published. We ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,meta分析,评审
doi：10.1093/bja/aew411
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2020.04.009
更新日期：2020-07-01 00:00:00
abstract：:It is generally accepted that halothane reduces airway and tissue resistance in lungs with preexisting airway tone. However, under conditions of resting airway tone, pulmonary resistance remains unaltered. In this study, we have determined the effects of halothane on respiratory system, pulmonary and chest wall resist...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/oxfordjournals.bja.a013443
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:There is little advice on the posture to be used when intubating the trachea. Does the stance used depend on experience? METHODS:Twenty-six subjects with varying experience of intubation were photographed during laryngoscopy of an intubation training mannequin. Posture was measured from the photographs and ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:Investigators planning dose-response studies of neuromuscular blockers have rarely used a priori power analysis to determine the minimal sample size their protocols require. Institutional Review Boards and peer-reviewed journals now generally ask for this information. This study outlines a proposed method fo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeq310
更新日期：2011-02-01 00:00:00
abstract：:Thirty-two patients received lumbar extradural anaesthesia for elective Caesarean section. The results obtained from this series were compared with those from a similar (control) group of parturients who received general anaesthesia. The extradural group (mothers and infants) were metabolically acidaemic relative to c...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/51.4.367
更新日期：1979-04-01 00:00:00
abstract：:Loss of resistance dorsal to the ligamentum flavum was recorded in 10 of 16 patients aged 43--75 yr whilst performing extradural anaesthesia at the L2--3 interspace via the midline approach. Degeneration of the interspinous ligament with cavity formation is observed frequently in the elderly and may account for false ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/51.3.253
更新日期：1979-03-01 00:00:00
abstract：BACKGROUND:Myocardial injury after noncardiac surgery is common, although the exact pathophysiology is unknown. It is plausible that hypotension after surgery is relevant for the development of myocardial injury. The authors evaluated whether low mean arterial pressures (MAPs) after surgery are related to an increased ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2017.11.002
更新日期：2018-01-01 00:00:00
