Antinociception by intrathecal midazolam involves endogenous neurotransmitters acting at spinal cord delta opioid receptors.

abstract：:The gliding characteristics were evaluated of 10-ml plastic syringes used to identify the extradural space by "loss of resistance" techniques. This was undertaken quantitatively, by measuring the force necessary to depress syringe plungers, and qualitatively, by examining travel characteristics in terms of the force a...

journal_title：British journal of anaesthesia

authors： Bricker SR,Coleman P

更新日期：1988-12-01 00:00:00

abstract：:Volume loading with crystalloid solution results in more pronounced haemodilution in patients who develop arterial hypotension during induction of extradural anaesthesia than in those who remain normotensive. The aim of this study was to describe the time course of this increase in haemodilution. Heart rate, systolic ...

journal_title：British journal of anaesthesia

authors： Drobin D,Hahn RG

更新日期：1996-08-01 00:00:00

abstract：:The time course of the plasma lignocaine concentration, following caudal anaesthesia, was studied in 11 healthy children (3.5-9 yr). Plasma lignocaine concentrations were measured for up to 6 h after administration (5 mg kg-1). Peak plasma concentration was 2.05 +/- 0.08 micrograms ml-1 and occurred at 28.2 +/- 2.9 mi...

journal_title：British journal of anaesthesia

authors： Ecoffey C,Desparmet J,Berdeaux A,Maury M,Giudicelli JF,Saint-Maurice C

更新日期：1984-12-01 00:00:00

abstract：:Pre- and postjunctional effects of three ethers (enflurane, diethyle ether, and methoxyflurane) and three non-ethers (chloroform, halothane, and trichloroethylene) were studied in the rat phrenic nerve diaphragm preparation using standard microelectrode recording techniques. Depression of postjunctional function inclu...

journal_title：British journal of anaesthesia

authors： Kennedy RD,Galindo AD

更新日期：1975-05-01 00:00:00

abstract：:We have measured plasma concentrations of bupivacaine after ilioinguinal block in children of different sizes. We studied 14 children with weights 10-15 kg and 17 children with weights 15-30 kg. Each child received 0.5% bupivacaine 0.25 ml kg-1 (1.25 mg kg-1) (Carbostesin, Astra, Germany). Venous blood was obtained be...

journal_title：British journal of anaesthesia

authors： Smith T,Moratin P,Wulf H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Recent investigations showed that isoflurane can induce pharmacological preconditioning. The present study aimed to compare the potency of four different halogenated anaesthetics to induce preconditioning. METHODS:Anaesthetized open-chest rabbits underwent 30 min of coronary artery occlusion followed by 3 h...

journal_title：British journal of anaesthesia

authors： Piriou V,Chiari P,Lhuillier F,Bastien O,Loufoua J,Raisky O,David JS,Ovize M,Lehot JJ

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:High-frequency oscillation (HFO) is a widely used lung-protective ventilatory strategy in paediatric and neonatal acute lung injury. Its safe and effective use has been hindered by inadequate recruitment of the lung during oscillation and, until recently, the lack of an adequately powered oscillator for use ...

journal_title：British journal of anaesthesia

authors： Moganasundram S,Durward A,Tibby SM,Murdoch IA

更新日期：2002-05-01 00:00:00

abstract：:We have studied the effect of P6 acupuncture on postoperative vomiting in 45 children undergoing tonsillectomy. After induction of anaesthesia and before the start of surgery, 50% of the patients received P6 acupuncture (in the middle of the ventral surface of the wrist) for 5 min. There was no difference in the incid...

journal_title：British journal of anaesthesia

authors： Yentis SM,Bissonnette B

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Short-axis ultrasound-guided placement of central venous catheters (CVCs) is widely accepted as safe practice. However, utilizing the long-axis approach could further improve safety, as it allows for better visualization of the needle as it is advanced to the target vessel. However, the long-axis approach ha...

journal_title：British journal of anaesthesia

authors： Ball RD,Scouras NE,Orebaugh S,Wilde J,Sakai T

更新日期：2012-01-01 00:00:00

abstract：:The pupils in brainstem-dead patients are classically fixed and dilated. We present a case of a brainstem-dead patient whose pupils displayed persistent asynchronous pupillary constriction and dilatation independent of external physical stimuli. Central causes for the phenomenon were excluded leaving an unexplained pe...

journal_title：British journal of anaesthesia

authors： Shlugman D,Parulekar M,Elston JS,Farmery A

更新日期：2001-05-01 00:00:00

abstract：:Robotic surgery pushes the frontiers of innovation in healthcare technology towards improved clinical outcomes. We discuss the evolution to five generations of robotic surgical platforms including stereotactic, endoscopic, bioinspired, microbots on the millimetre scale, and the future development of autonomous systems...

journal_title：British journal of anaesthesia

authors： Ashrafian H,Clancy O,Grover V,Darzi A

更新日期：2017-12-01 00:00:00

abstract：:The effect of gas leakage around an uncuffed tracheal tube on the performance of Heat and Moisture Exchangers (HME) was examined experimentally. Such leaks were shown to cause measurable decreases in the humidity output and efficiency of HME. The magnitude of the decrease in humidity output was shown to be dependent u...

journal_title：British journal of anaesthesia

authors： Tilling SE,Hayes B

更新日期：1987-09-01 00:00:00

abstract：:The relative analgesic efficacy and side-effect profile of peripheral nerve blockade (PNB) techniques compared with lumbar epidural analgesia for major knee surgery is unclear. We undertook a systematic review and meta-analysis of all randomized trials comparing epidural analgesia with PNB for major knee surgery. Eigh...

journal_title：British journal of anaesthesia

authors： Fowler SJ,Symons J,Sabato S,Myles PS

更新日期：2008-02-01 00:00:00

abstract：:We gave either midazolam or propofol for induction of anaesthesia to 140 ASA I or II female patients (18-60 yr). ED50 values were obtained by probit analysis for three clinical end-points: loss of response to command; loss of eyelash reflex; failure to respond to application of an anaesthetic face mask delivering 1% i...

journal_title：British journal of anaesthesia

authors： McClune S,McKay AC,Wright PM,Patterson CC,Clarke RS

更新日期：1992-09-01 00:00:00

abstract：:In obstetric patients undergoing postpartum tubal ligation, we found that metoclopramide produced dose-dependent prolongation of suxamethonium-induced neuromuscular block. Mean block times after suxamethonium 1 mg kg-1 were 8.0 min, 9.83 min and 12.45 min for control and metoclopramide 10 mg and metoclopramide 20 mg g...

journal_title：British journal of anaesthesia

authors： Kao YJ,Tellez J,Turner DR

更新日期：1990-08-01 00:00:00

abstract：:Sepsis is a constellation of clinical signs and symptoms resulting from excessive systemic host inflammatory response to infection. This inflammatory response is largely mediated by cytokines, which are released into the systemic circulation. Plasma concentrations of specific cytokines, TNF alpha, IL-1 beta, IL-6 and ...

journal_title：British journal of anaesthesia

authors： Blackwell TS,Christman JW

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Data on contributors to between-individual variability in overall tramadol clearance and O-demethyl tramadol (M1) formation in preterm neonates and young infants are limited. METHODS:A population pharmacokinetic analysis of tramadol and M1 was undertaken using non-linear mixed effects model. Covariate analy...

journal_title：British journal of anaesthesia

authors： Allegaert K,van den Anker JN,de Hoon JN,van Schaik RH,Debeer A,Tibboel D,Naulaers G,Anderson BJ

更新日期：2008-04-01 00:00:00

abstract：:Acetazolamide, a carbonic anhydrase inhibitor, may cause significant disturbances in carbon dioxide transport and elimination. In this study, end-tidal carbon dioxide monitoring has been used to study the correlation between arterial carbon dioxide (PaCO2) and end-tidal carbon dioxide partial pressure (PE'CO2) in rabb...

journal_title：British journal of anaesthesia

authors： Lee TS

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Cardiac output (CO) monitoring is helpful in the assessment of critically ill pregnant women, but invasive monitors are often unsuitable for use. We aimed to measure agreement between the non-invasive ultrasound cardiac output monitor (USCOM) and three-dimensional transthoracic echocardiography (3D-TTE) in p...

journal_title：British journal of anaesthesia

authors： McNamara H,Barclay P,Sharma V

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Ketamine is widely used as an i.v. anaesthetic agent and as a drug of abuse. Hepatocytes contribute to the metabolism of endogenous and exogenous substances. This study evaluated the toxic effects of S-(+)-ketamine and possible mechanisms using human hepatoma HepG2 cells as the experimental model. METHODS:H...

journal_title：British journal of anaesthesia

authors： Lee ST,Wu TT,Yu PY,Chen RM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...

journal_title：British journal of anaesthesia

authors： Chen A,Elia N,Dunaiceva J,Rudiger A,Walder B,Bollen Pinto B

更新日期：2020-06-01 00:00:00

abstract：:Intracuff pressure (c.p.) was measured continuously in 12 patients during prolonged periods of tracheal intubation. High residual volume--low pressure (floppy) and low residual volume--high pressure (conventional) cuffs were studied. The mean baseline c.p. at minimal occluding pressure was significantly smaller in flo...

journal_title：British journal of anaesthesia

authors： Jacobson L,Greenbaum R

更新日期：1981-01-01 00:00:00

abstract：:A simple method of adapting a pressure-cycled ventilator of the flow generator type to ventilate patients on a circle-absorber anaesthetic system is described. Standard lengths of corrugated black rubber tubing are placed between the ventilator and the circle-absorber is deadspace, replacing the reservoir bag. The per...

journal_title：British journal of anaesthesia

authors： Jeal DE

更新日期：1977-03-01 00:00:00

abstract：:The ventilatory effects of single i.v. doses of morphine 0.1 mg kg-1, pethidine 0.67 mg kg-1 and methadone 0.1 mg kg-1 were compared after ophthalmic surgery in an open, randomized study in 30 children aged 3-8 yr. Ventilatory changes after each drug had distinctive profiles, with appreciable individual variation. Acu...

journal_title：British journal of anaesthesia

authors： Hamunen K

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Cardiac surgery with cardiopulmonary bypass (CPB) is commonly perceived as a risk factor for decline in renal function, especially in patients with preoperative renal dysfunction. There are few data on the effects of CPB on renal function in patients with mild preoperative renal dysfunction. The purpose of t...

journal_title：British journal of anaesthesia

authors： Loef BG,Henning RH,Navis G,Rankin AJ,van Oeveren W,Ebels T,Epema AH

更新日期：2008-06-01 00:00:00

abstract：:The use of di-isopropyl phenol (Diprivan) for induction of anaesthesia was assessed in doses ranging from 1 to 3 mg kg-1. With less than 1.75mg kg-1 not all patients were anaesthetized; 2.0 mg kg-1 appeared to be a satisfactory induction dose. Involuntary muscle movement, cough and hiccup at induction were rare with a...

journal_title：British journal of anaesthesia

authors： Briggs LP,Clarke RS,Dundee JW,Moore J,Bahar M,Wright PJ

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Severely obese parturients have increased 'cannot intubate, cannot oxygenate' risk during Caesarean section under general anaesthesia. Front-of-neck access (FONA) at the cricothyroid membrane (CTM) is definitive management; however, attempted FONA can fail. Point-of-care ultrasonography may provide useful in...

journal_title：British journal of anaesthesia

authors： Gadd K,Wills K,Harle R,Terblanche N

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Better education of clinicians is expected to enhance patient safety. An important component of education is adherence to standard protocols, which are mainly available in written form. Believing in the potential power of videos, we hypothesized that the introduction of an educational video, based on an inst...

journal_title：British journal of anaesthesia

authors： Kandler L,Tscholl DW,Kolbe M,Seifert B,Spahn DR,Noethiger CB

更新日期：2016-05-01 00:00:00

abstract：:We have estimated the effect of omitting antagonism of neuromuscular block on postoperative nausea and vomiting. A systematic search (MEDLINE, EMBASE, Biological Abstracts, Cochrane library, reference lists and hand searching; no language restriction, up to March 1998) was performed for relevant randomized controlled ...

journal_title：British journal of anaesthesia

authors： Tramèr MR,Fuchs-Buder T

更新日期：1999-03-01 00:00:00

abstract：:We describe three histaminoid reactions occurring on induction of anaesthesia. The patients were all resuscitated successfully and subsequent skin testing suggested sensitivity to rocuronium. In this hospital, the incidence of such reactions is of the order of 1 in 3000. This may be coincidental but suggests that ther...

journal_title：British journal of anaesthesia

authors： Neal SM,Manthri PR,Gadiyar V,Wildsmith JA

更新日期：2000-01-01 00:00:00