End-tidal partial pressure of carbon dioxide does not accurately reflect PaCO2 in rabbits treated with acetazolamide during anaesthesia.

Abstract:

:Acetazolamide, a carbonic anhydrase inhibitor, may cause significant disturbances in carbon dioxide transport and elimination. In this study, end-tidal carbon dioxide monitoring has been used to study the correlation between arterial carbon dioxide (PaCO2) and end-tidal carbon dioxide partial pressure (PE'CO2) in rabbits treated with acetazolamide. A significant difference in (PaCO2-PE'CO2) developed immediately after administration of acetazolamide and persisted for more than 2 h. It is concluded that PE'CO2 did not reflect accurately PaCO2 and the ventilatory status of the rabbit which received acetazolamide within 2 h.

journal_name

Br J Anaesth

authors

Lee TS

doi

10.1093/bja/73.2.225

subject

Has Abstract

pub_date

1994-08-01 00:00:00

pages

225-6

issue

2

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)44636-8

journal_volume

73

pub_type

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