Cardiorespiratory effects of high frequency intermittent positive pressure ventilation in the dog.

Abstract:

:The cardiorespiratory effects of increasing respiratory frequency were investigated in two groups of dogs ventilated mechanically with a system which minimized apparatus and anatomical deadspace. In one group minute volume was constant whilst frequency was increased; in the second group minute volume was increased to maintain normal PaCO2. The reduction in tidal volume with increasing frequency was accompanied by a reduction in physiological deadspace. However, the reduction in deadspace was proportionally less than the decrease in tidal volume, so that the deadspace/tidal volume ratio increased. The peak airway pressures were minimal at a frequency of 45 b.p.m. At frequencies of 60 b.p.m. and more, the lung failed to empty so that peak airway pressures were increased and cardiac output decreased.

journal_name

Br J Anaesth

authors

Chakrabarti MK,Sykes MK

doi

10.1093/bja/52.5.475

subject

Has Abstract

pub_date

1980-05-01 00:00:00

pages

475-82

issue

5

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)41217-7

journal_volume

52

pub_type

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