Abstract：
:Volume loading with crystalloid solution results in more pronounced haemodilution in patients who develop arterial hypotension during induction of extradural anaesthesia than in those who remain normotensive. The aim of this study was to describe the time course of this increase in haemodilution. Heart rate, systolic arterial pressure and blood haemoglobin concentration were measured every 3 min during the onset of extradural anaesthesia in 22 elderly men undergoing short urological operations. Fluid therapy consisted of 15 ml/kg body weight of Ringer's acetate solution. Patients with a decrease in systolic pressure of > 25% retained 50% (SD 12%) of the infused fluid in the circulation, while the others retained 36 (8%) (P < 0.002). In both groups, arterial hypotension was followed by increased haemodilution after a delay of as much as 15 min. This suggests that, despite volume loading, there is relative hypovolaemia throughout the development of hypotension.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Drobin D,Hahn RGdoi
10.1093/bja/77.2.223subject
Has Abstractpub_date
1996-08-01 00:00:00pages
223-6issue
2eissn
0007-0912issn
1471-6771pii
S0007-0912(17)43590-2journal_volume
77pub_type
杂志文章abstract：:We have studied the effects of stepwise increasing infusion rates of propofol 200-500 micrograms kg-1 min-1 on blood concentrations of propofol and the disposition and clearance of a bolus dose of indocyanine green (ICG) 0.5 mg kg-1 in 10 acutely instrumented dogs. Drug concentrations and ICG clearance were measured 3...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/72.4.451
更新日期：1994-04-01 00:00:00
abstract：:To understand the sequential response of the autonomic nervous system to pregnancy, we studied heart rate variability in 23 first trimester, 23 second trimester and 21 third trimester pregnant women. Twenty non-pregnant women were recruited as controls. Time and frequency domain measures of heart rate variability in t...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/oxfordjournals.bja.a013433
更新日期：2000-03-01 00:00:00
abstract：:The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/68.4.344
更新日期：1992-04-01 00:00:00
abstract：:We have performed a prospective, randomized, double-blind clinical study to assess the efficacy of ondansetron, droperidol, or both, in preventing postoperative emesis. We studied 242 patients undergoing biliary or gynaecological surgery under general anaesthesia. Shortly before induction of anaesthesia, patients rece...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/83.5.813
更新日期：1999-11-01 00:00:00
abstract：:Respiratory obstruction has been reported as a complication of carotid endarterectomy; the causes include traumatic mucosal oedema, direct tracheal compression by haematoma and oedema secondary to lymphatic and venous congestion. We report four cases of acute respiratory obstruction complicating carotid endarterectomy...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/76.1.156
更新日期：1996-01-01 00:00:00
abstract：:We present a new pattern of nerve stimulation--double burst stimulation (DBS)--to detect residual neuromuscular block manually. The DBS consists of two short lasting, 50-Hz tetanic stimuli or bursts separated by a 750-ms interval. The response to this pattern of stimulation is two single separated muscle contractions ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/62.3.274
更新日期：1989-03-01 00:00:00
abstract：:Atropine and glycopyrronium are frequently used for premedication to reduce oral and respiratory secretions and prevent bradycardia. Glycopyrronium is said to have similar antisialagogue effects, but is less likely to cause significant tachycardia than atropine. Different antimuscarinic receptor selectivity patterns c...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/74.5.549
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND:Growing evidences indicate that inhalational anaesthetics can enhance the growth and malignant potential of tumour cells and may affect tumour recurrence after surgery. Tumour stem cells play a vital role in tumour recurrence. This study investigates the effect of sevoflurane on glioma stem cells (GSCs) in v...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeu402
更新日期：2015-05-01 00:00:00
abstract：:We have compared mivacurium and succinylcholine in 27 paediatric patients with mild (Child's A) to moderate (Child's B) liver disease undergoing oesophagogastroduodenoscopy (OGD) and injection of oesophageal varices, with 10 healthy children receiving mivacurium for ENT procedures. With mivacurium 0.2 mg kg-1, the sev...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/81.3.463
更新日期：1998-09-01 00:00:00
abstract：BACKGROUND:Hip fracture is a condition with high mortality and morbidity in elderly frail patients. Intraoperative fluid optimization may be associated with benefit in this population. We investigated whether intraoperative fluid management using pulse-contour analysis cardiac monitoring, compared with standard care in...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aeu386
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:There have been few studies comparing the response to asphyxia and the effectiveness of typical cardiopulmonary resuscitation (CPR) using exogenous epinephrine administration and manual closed-chest compression between total intravenous anaesthesia (TIVA) and inhalational anaesthesia. METHODS:Twenty pigs we...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeg259
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:Investigators planning dose-response studies of neuromuscular blockers have rarely used a priori power analysis to determine the minimal sample size their protocols require. Institutional Review Boards and peer-reviewed journals now generally ask for this information. This study outlines a proposed method fo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeq310
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Low-dose droperidol is suggested to be cost-effective in preventing nausea and vomiting after ambulatory surgery. This clinical study evaluated patient postural stability using a computerized force platform after an i.v. dose of droperidol 0.625 mg in outpatients undergoing gynaecological dilatation and cure...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/88.6.819
更新日期：2002-06-01 00:00:00
abstract：:We investigated in 60 patients scheduled for elective aorto-coronary bypass grafting if loud sounds by themselves can induce cardiovascular responses and if these could be related to mid-latency auditory evoked potentials (MLAEP). Anaesthesia was induced in group I (n = 20) with flunitrazepam-fentanyl 0.01 mg kg-1 and...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/72.3.307
更新日期：1994-03-01 00:00:00
abstract：:Plain bupivacaine 0.5% or 0.75% was injected intrathecally in four groups of 10 patients. Group A received 0.75% bupivacaine 2.7 ml at L3/4, group B 0.5% bupivacaine 4 ml at L3/4, group C 0.75% bupivacaine 2.7 ml at L2/3 and group D 0.75% bupivacaine 2 ml at L3/4. A very wide range of height of block was found in each...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/58.3.292
更新日期：1986-03-01 00:00:00
abstract：BACKGROUND:Several medications have proved to be useful in preventing postoperative nausea and vomiting (PONV). However, routine antiemetic prophylaxis is not cost-effective. We evaluated the accuracy and discriminating power of an artificial neural network (ANN) to predict PONV. METHODS:We analysed data from 1086 in-...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/ael282
更新日期：2007-01-01 00:00:00
abstract：:A technique of induction of anaesthesia using propanidid, lignocaine and suxamethonium is described, and the muscle fasciculations that follow it are shown to be significantly less than those accompanying induction with methohexitone and suxamethonium. ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/47.6.723
更新日期：1975-06-01 00:00:00
abstract：:The effect of the administration of propranolol 0.15 mg per kg body weight i.v. on the metabolic response to pelvic surgery was compared with results in similar patients who had not received propranolol. The only significant difference between the two groups was a lower plasma insulin concentration in the beta-blockad...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/52.12.1231
更新日期：1980-12-01 00:00:00
abstract：:The effect of diluting propofol in 5% dextrose on the incidence of i.v. injection pain was studied in 100 adult patients. Severe injection pain occurred in 32% (16 patients) who received undiluted propofol, compared with 10% (five patients) who received dilute propofol. We concluded that the dilution of propofol signi...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/62.2.202
更新日期：1989-02-01 00:00:00
abstract：BACKGROUND:The 15-item Quality of Recovery (QoR-15) scale is a validated patient-reported outcome questionnaire that measures the quality of postoperative recovery. This study aimed to validate a translated Korean version of QoR-15 (QoR-15K) in a broad range of surgical patients. METHODS:After Korean translation of th...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2020.06.040
更新日期：2020-10-01 00:00:00
abstract：:The pharmacokinetics of edrophonium were determined in patients anaesthetized with nitrous oxide and halothane undergoing kidney transplant nephrectomy (n=6) or transplantation of a live related donor kidney (n = 6). Serum concentrations of edrophonium were assayed by high pressure liquid chromatography and pharmacoki...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/53.12.1311
更新日期：1981-12-01 00:00:00
abstract：BACKGROUND:The diagnosis of abdominal compartment syndrome depends upon the demonstration of an elevated intra-abdominal pressure (IAP). Direct measures of IAP are impractical in the critical care unit; intravesical pressure (IVP) and intragastric pressure (IGP) should represent acceptable surrogate measures. IVP is th...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aem060
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:Acute pulmonary embolism (APE) is an important clinical problem in patients after major surgery and often remains a difficult diagnosis because of unspecific clinical symptoms. Therefore, we investigated the role of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for the detection of APE. MET...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aes315
更新日期：2012-12-01 00:00:00
abstract：:Fires and explosions have occurred in the operating theatre for many years. Flammable inhalation anaesthetic agents were responsible for many incidents in the past, but these are no longer available in many countries. Other causes of fires and explosions still exist in the operating theatre and, from time to time, res...
journal_title：British journal of anaesthesia
pub_type： 历史文章,杂志文章
doi：10.1093/bja/73.6.847
更新日期：1994-12-01 00:00:00
abstract：:In 15 patients (ASA I-II) undergoing intraabdominal gynaecological surgery, muscle paralysis for tracheal intubation and surgery was achieved by a combined bolus and demand infusion of vecuronium. The initial loading dose of 67 micrograms kg-1 and the rate of subsequent infusion were determined by evaluation of the ta...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/61.4.479
更新日期：1988-10-01 00:00:00
abstract：:Delirium commonly manifests in the postoperative period as a clinical syndrome resulting from acute brain dysfunction or encephalopathy. Delirium is characterized by acute and often fluctuating changes in attention and cognition. Emergence delirium typically presents and resolves within minutes to hours after terminat...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aew475
更新日期：2017-08-01 00:00:00
abstract：:We report the extradural administration of low-dose morphine in 10 ml of 10% dextrose (2-3 mg) to 98 adult patients with various types of acute and chronic pain. Extradural morphine injections were given either via a Tuohy needle (single or repeat injection) or via an extradural catheter. Pain relief was evaluated by ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/52.3.247
更新日期：1980-03-01 00:00:00
abstract：:Midazolam is often used for paediatric premedication. We have compared two methods of administering midazolam intranasally in 44 surgical day-case children allocated randomly to receive midazolam 0.2 mg kg-1 as drops or midazolam 0.1 mg kg-1 from an intranasal spray device. Behaviour was recorded on a four-point scale...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/81.6.865
更新日期：1998-12-01 00:00:00
abstract：:Some recipients of isolated, orthotopic lung transplants have now survived to leave hospital with greatly improved quality of life. Inevitably, the successful demonstration of the feasibility of these operations means that transplant centres throughout the world may wish to participate in a lung transplant programme. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/61.4.468
更新日期：1988-10-01 00:00:00
abstract：:We have studied the plasma concentrations (Cp) and pharmacokinetics of sufentanil injected i.v. (IVS), intradurally (IS) or extradurally (ES) under general anaesthesia in 31 patients undergoing major abdominal surgery. Sufentanil appeared in plasma very rapidly and Cpmax was also attained rapidly after both extradural...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/66.4.458
更新日期：1991-04-01 00:00:00
