The use of propanidid and lignocaine to reduce suxamethonium fasciculations.

abstract：BACKGROUND:Circadian rhythms coordinate almost all physiological functions and are implicated in major disease development. Even though circadian rhythms have a major impact on human health, little is known about how they affect general anaesthesia. The purpose of this study was to understand if the time of day affects...

journal_title：British journal of anaesthesia

authors： Szolnoki J,Polaner DM,Eckle T

更新日期：2018-10-01 00:00:00

abstract：:Animal studies suggest that alpha 2 agonists inhibit the chemoreceptor response to hypoxia. We have examined the effect of oral clonidine on the ventilatory response to sustained, isocapnic hypoxia (SpO2 79.7% (SD 1.1%) for 20 min) in eight male subjects. The hypoxic ventilatory response was measured before and after ...

journal_title：British journal of anaesthesia

authors： Foo IT,Warren PM,Drummond GB

更新日期：1996-02-01 00:00:00

abstract：:The effects of diazepam, which acts at GABAA receptors to enhance the effects of GABA, and ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, on local rates of cerebral glucose utilization (ICMRglc) were examined in unrestrained rats. Four groups were studied: vehicle-injected controls; and ketamine...

journal_title：British journal of anaesthesia

authors： Eintrei C,Sokoloff L,Smith CB

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Beta-adrenergic agonists enhance behavioural and electroencephalographic arousal reactions. We explored whether adding esmolol, a short-acting beta(1)-adrenoceptor antagonist, to propofol anaesthesia modified the bispectral index (BIS) during induction of anaesthesia and orotracheal intubation. METHODS:Fift...

journal_title：British journal of anaesthesia

authors： Menigaux C,Guignard B,Adam F,Sessler DI,Joly V,Chauvin M

更新日期：2002-12-01 00:00:00

abstract：:Methylene blue-treated fresh-frozen plasma (MB-FFP) is mainly used in Europe. The advantage of the methylene blue system is that units can be treated individually. The combined action of methylene blue and illumination is a photodynamic process preventing viral RNA and DNA replication. We report the first immediate al...

journal_title：British journal of anaesthesia

authors： Dewachter P,Castro S,Nicaise-Roland P,Chollet-Martin S,Le Beller C,Lillo-le-Louet A,Mouton-Faivre C

更新日期：2011-05-01 00:00:00

abstract：:We have compared the effects of progressive (30% and 60%) in vitro haemodilution with hydroxyethyl starch (HES), gelatin (GEL) and albumin (ALB) with haemodilution using 0.9% saline in 96 patients by thrombelastography. Haemodilution with HES, GEL and ALB significantly (P < 0.05) compromised coagulation time (k), angl...

journal_title：British journal of anaesthesia

authors： Egli GA,Zollinger A,Seifert B,Popovic D,Pasch T,Spahn DR

更新日期：1997-06-01 00:00:00

abstract：:Bilateral superior laryngeal nerve block was combined with topical application of local anaesthetic 140 times in 135 patients to anaesthetize the upper airway and facilitate tracheal intubation, laryngeal instrumentation, or to diminish the response to the endotracheal tube, in a patient already intubated. The techniq...

journal_title：British journal of anaesthesia

authors： Gotta AW,Sullivan CA

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:There is considerable evidence that the use of tidal volumes <6 ml kg(-1) predicted body weight (PBW) reduces mortality in mechanically ventilated patients. We evaluated the effectiveness of using a large screen displaying delivered tidal volume in ml kg(-1) (PBW) for reducing tidal volumes. METHODS:We asse...

journal_title：British journal of anaesthesia

authors： Bourdeaux CP,Birnie K,Trickey A,Thomas MJ,Sterne J,Donovan JL,Benger J,Brandling J,Gould TH

更新日期：2015-08-01 00:00:00

abstract：:One hundred patients presenting for surgical treatment of fractured neck of femur were allocated to receive either spinal (SAB) or general (GA) anaesthesia. Before operation, the mean PaO2 was 9.04 kPa. There was a significant decrease in PaO2 of 0.68 kPa in GA group at 1 h after operation, while blood-gas values were...

journal_title：British journal of anaesthesia

authors： McKenzie PJ,Wishart HY,Dewar KM,Gray I,Smith G

更新日期：1980-01-01 00:00:00

abstract：:The effect of incubation at 37 degrees C, 46 degrees C, 47 degrees C and 48 degrees C for 1 h on the osmotic fragility of blood was determined. Blood taken from volunteers into ACD and CPD was examined after 1, 7, 14 and 21 days of storage. In addition, 22-day-old blood stored in CPD was examined. The osmotic fragilit...

journal_title：British journal of anaesthesia

authors： Van der Walt JH,Russell WJ

更新日期：1978-08-01 00:00:00

abstract：:We have compared deep body temperature (DBT) measured at the forehead with the core temperatures of the nasopharynx, oesophagus and rectum during the warming phase of cardiopulmonary bypass (CPB) (moderate hypothermia of 26.7-29.6 degrees C) in 12 patients. DBT was measured transcutaneously by an insulated thermistor ...

journal_title：British journal of anaesthesia

authors： Sakuragi T,Mukai M,Dan K

更新日期：1993-10-01 00:00:00

abstract：:Using cats with chronically implanted brain electrodes, we have compared the effects of propofol on CNS electrical activities with those of thiopentone. Ten cats were allocated to receive either propofol (n = 5) or thiopentone (n = 5). Cats were anaesthetized initially with 4% halothane in oxygen. The trachea was intu...

journal_title：British journal of anaesthesia

authors： Tomoda K,Shingu K,Osawa M,Murakawa M,Mori K

更新日期：1993-09-01 00:00:00

abstract：Background:Identification of statistically reliable outcomes for comparison among anaesthetists is challenging. Time-weighted intraoperative mean arterial pressure <65 mm Hg (AUC 65 ) is associated with increased odds for myocardial damage. We explored retrospectively whether such hypotension before incision was statis...

journal_title：British journal of anaesthesia

authors： Epstein RH,Dexter F,Schwenk ES

更新日期：2017-07-01 00:00:00

abstract：:Carotid endarterectomy is commonly conducted under regional (deep, superficial, intermediate, or combined) cervical plexus block, but it is not known if complication rates differ. We conducted a systematic review of published papers to assess the complication rate associated with superficial (or intermediate) and deep...

journal_title：British journal of anaesthesia

authors： Pandit JJ,Satya-Krishna R,Gration P

更新日期：2007-08-01 00:00:00

abstract：:This was a prospective, non-randomized, multicentre study of rocuronium (Org 9426) in 40 elective Caesarean section patients at full term without fetal distress. Anaesthesia was induced with thiopentone 4-6 mg kg-1 i.v. and rocuronium 0.6 mg kg-1 and maintained with isoflurane and nitrous oxide in oxygen. Monitors inc...

journal_title：British journal of anaesthesia

authors： Abouleish E,Abboud T,Lechevalier T,Zhu J,Chalian A,Alford K

更新日期：1994-09-01 00:00:00

abstract：:Continuous intercostal nerve blockade was used to provide analgesia after cholecystectomy. The blockade was maintained by the insertion of a single extradural catheter into an appropriate intercostal space and by "topping-up" with local anaesthetic on demand. Of the patients studied, 92%, and 76%, required no addition...

journal_title：British journal of anaesthesia

authors： Murphy DF

更新日期：1983-06-01 00:00:00

abstract：:Forty patients (age range 60-79 yr) undergoing transurethral surgery were allocated randomly to receive 0.5% plain bupivacaine 4 ml at the L2-3 (n = 20) or L4-5 (n = 20) space. The solution was injected over 30 s with the patient in the sitting position. The patient was kept sitting for 2 min, then placed supine and, ...

journal_title：British journal of anaesthesia

authors： Olsen KH,Nielsen TH,Kristoffersen E,Husegaard HC,Wernberg M,Dørup J

更新日期：1990-02-01 00:00:00

abstract：:The isolated rat hepatocyte model has been used to assess the hepatotoxicity of a number of i.v. anaesthetic induction agents. Ketamine, Althesin and CCI 12923 (minaxolone) all inhibited gluconeogenesis and urea formation from alanine. There was also a decrease in the cell ATP concentration, and a dose-related increas...

journal_title：British journal of anaesthesia

authors： Sear JW,McGivan JD

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:There have been few studies comparing the response to asphyxia and the effectiveness of typical cardiopulmonary resuscitation (CPR) using exogenous epinephrine administration and manual closed-chest compression between total intravenous anaesthesia (TIVA) and inhalational anaesthesia. METHODS:Twenty pigs we...

journal_title：British journal of anaesthesia

authors： Kurita T,Morita K,Kazama T,Sato S

更新日期：2003-12-01 00:00:00

abstract：:We tested the hypothesis that the solvent for etomidate was a factor in the incidence of pain and other side effects after injection, and that these were associated with histamine release. Nine of 10 volunteers who received etomidate in a propylene glycol formulation reported moderate to severe pain on injection; only...

journal_title：British journal of anaesthesia

authors： Doenicke AW,Roizen MF,Hoernecke R,Lorenz W,Ostwald P

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Thermal, mechanical, and electrical stimuli are often used in acute pain studies and cause qualitatively different pain sensations. Yet, the comparative electroencephalogram (EEG) changes caused by these stimuli have not been studied. We hypothesized that because these stimuli cause different pain sensations...

journal_title：British journal of anaesthesia

authors： Murrell JC,Mitchinson SL,Waters D,Johnson CB

更新日期：2007-03-01 00:00:00

abstract：:We have investigated the effect of four doses of remifentanil on the incidence of respiratory depression and somatic response at incision. Remifentanil was administered as a loading dose of 0.125, 0.25, 0.375 or 0.5 microgram kg-1 and at a maintenance infusion rate of 0.025, 0.05, 0.075 or 0.1 microgram kg-1 min-1, re...

journal_title：British journal of anaesthesia

authors： Peacock JE,Luntley JB,O'Connor B,Reilly CS,Ogg TW,Watson BJ,Shaikh S

更新日期：1998-04-01 00:00:00

abstract：:The analgesic effects and bioavailability of a slow-release preparation of morphine (Duromorph) were studied in 12 patients with acute postoperative pain. Duromorph produced significant analgesia within 1-2 h of administration i.m., and there was a progressive decrease in the mean pain score for at least 8 h. None of ...

journal_title：British journal of anaesthesia

authors： Charway CL,Calvey TN,Williams NE,Murray GR

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which reflect spinal excitability, has been shown for propofol. We have assessed the concentration-dependent F-wave suppression by propofol and related it to th...

journal_title：British journal of anaesthesia

authors： Baars JH,Tas S,Herold KF,Hadzidiakos DA,Rehberg B

更新日期：2006-01-01 00:00:00

abstract：:The identification of a serum marker to assist in the diagnosis of cerebral injury after cardiac surgery is potentially useful. S100 protein is an early marker of cerebral damage. It is released after cardiac surgery performed under cardiopulmonary bypass (CPB). Its level is correlated with the duration of CPB, deep c...

journal_title：British journal of anaesthesia

authors： Ali MS,Harmer M,Vaughan R

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The minimum alveolar concentration (MAC) is a traditional index of the hypnotic potency of an inhalational anaesthetic. To investigate the anaesthetic as well as the unwanted effects of xenon (Xe) in a swine model, it is useful to know MAC(Xe). METHODS:The study was performed using ten swine (weight 27.8-35...

journal_title：British journal of anaesthesia

authors： Hecker KE,Horn N,Baumert JH,Reyle-Hahn SM,Heussen N,Rossaint R

更新日期：2004-03-01 00:00:00

abstract：:Data from two published and one new meta-analysis were reviewed to compare the antiemetic efficacy of three different anaesthetic regimens: (i) propofol anaesthesia compared with another anaesthetic (control); (ii) anaesthesia without nitrous oxide compared with the same anaesthetic with nitrous oxide (control); (iii)...

journal_title：British journal of anaesthesia

authors： Tramèr M,Moore A,McQuay H

更新日期：1997-03-01 00:00:00

abstract：:Critical narrowing of the dependent airways was examined in anaesthetized dogs with closed chests. Two techniques were used, (a) "closing" volume (CV), measured from the expired nitrogen plateau and (b) tantalum bronchography, to measure the calibre of airways of 3-8 mm diameter in the upper (UZ), middle (MZ) and lowe...

journal_title：British journal of anaesthesia

authors： Jones JG,Graf PD,Lemen R

更新日期：1978-08-01 00:00:00

abstract：:We have compared insertion of a tracheal tube and laryngeal mask airway (LMA) both with and without the presence of a tube in the oesophagus in 20 ASA I and II patients undergoing elective laparoscopy. After induction of anaesthesia and neuromuscular block, we measured the times for an experienced anaesthetist to corr...

journal_title：British journal of anaesthesia

authors： Pace NA,Gajraj NM,Pennant JH,Victory RA,Johnson ER,White PF

更新日期：1994-11-01 00:00:00

abstract：:Midazolam is often used for paediatric premedication. We have compared two methods of administering midazolam intranasally in 44 surgical day-case children allocated randomly to receive midazolam 0.2 mg kg-1 as drops or midazolam 0.1 mg kg-1 from an intranasal spray device. Behaviour was recorded on a four-point scale...

journal_title：British journal of anaesthesia

authors： Griffith N,Howell S,Mason DG

更新日期：1998-12-01 00:00:00