Deep body temperature during the warming phase of cardiopulmonary bypass.

abstract：BACKGROUND:Signalling of several G-protein-coupled receptors of the Gq/11 family is time-dependently inhibited by local anaesthetics (LAs). Since LA-induced modulation of muscarinic m1 and m3 receptor function may explain their beneficial effects in clinical practice, such as decreased postoperative cognitive dysfuncti...

journal_title：British journal of anaesthesia

authors： Picardi S,Stevens MF,Hahnenkamp K,Durieux ME,Lirk P,Hollmann MW

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:In the context of an increasing number of publications of trial data analysed by Bayesian methods, clinicians need support to better understand Bayesian statistical methods. The existing checklists are intended for people who already know these methods. We aimed to establish and validate a checklist that c...

journal_title：British journal of anaesthesia

authors： Ferreira D,Barthoulot M,Pottecher J,Torp KD,Diemunsch P,Meyer N

更新日期：2020-08-01 00:00:00

abstract：:In vitro experiments on the rat phrenic nerve-hemidiaphragm preparation, stimulated directly or indirectly with supramaximal impulses at 0.1 Hz revealed that pethidine in concentrations greater than 5 micrograms ml-1 caused a rapid increase of the twitch. This was maximal (60% increase during direct and 70% increase d...

journal_title：British journal of anaesthesia

authors： Boros M,Chaudhry IA,Nagashima H,Duncalf RM,Sherman EH,Foldes FF

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:The oesophageal leak pressure is defined as the pressure which breaks the seal between the cuff of a supraglottic airway and the peri-cuff mucosa, allowing penetration of fluid into the pharynx and the oral cavity. As a consequence, a decrease in this variable increases the risk of reflux and can lead to pul...

journal_title：British journal of anaesthesia

authors： Hensel M,Schmidbauer W,Geppert D,Sehner S,Bogusch G,Kerner T

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Clonidine is an alpha 2 adrenergic agonist with analgesic properties. This study aimed to see if the addition of clonidine to morphine when given by patient-controlled analgesia (PCA) would improve analgesia beyond the first 12 h after surgery. METHODS:Sixty patients undergoing lower abdominal surgery were ...

journal_title：British journal of anaesthesia

authors： Jeffs SA,Hall JE,Morris S

更新日期：2002-09-01 00:00:00

abstract：:Integrated electromyographic studies in burned patients, and in normal controls, during the administration of small doses of suxamethonium (0.1 or 0.2 mg kg-1) have shown that the level of paralysis and the duration of paralysis are significantly increased in burn patients and that the effect is greater with larger bu...

journal_title：British journal of anaesthesia

authors： Brown TC,Bell B

更新日期：1987-08-01 00:00:00

abstract：:The neuromuscular blocking effects of Org 9426, the 2-morpholino, 16-allyl-pyrrolidino derivative of the 3-desacetoxy analogue of vecuronium have been investigated in anaesthetized patients. Based on data from a pilot study, two doses, 250 and 500 micrograms kg-1 (estimated as the ED90 and 2 x ED90, respectively) were...

journal_title：British journal of anaesthesia

authors： Wierda JM,de Wit AP,Kuizenga K,Agoston S

更新日期：1990-04-01 00:00:00

abstract：:Percutaneous dilatational tracheostomy (PDT) is associated with a number of life-threatening complications. We present a case of massive and fatal arterial haemorrhage that occurred in the intensive care unit during an elective PDT on an 86-year-old woman following earlier evacuation of a traumatic subdural haematoma....

journal_title：British journal of anaesthesia

authors： Shlugman D,Satya-Krishna R,Loh L

更新日期：2003-04-01 00:00:00

abstract：:We have compared the effects of dexmedetomidine and propofol on endocrine, metabolic, inflammatory and cardiovascular responses in patients in the intensive care unit (ICU) after major surgery. Twenty patients who were expected to require 8 h of post-operative sedation and ventilation were allocated randomly to receiv...

journal_title：British journal of anaesthesia

authors： Venn RM,Bryant A,Hall GM,Grounds RM

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that ultrasound guidance for paediatric regional anaesthesia can improve the quality of upper extremity and neuraxial blocks. We therefore investigated whether ultrasound guidance for sciatic and femoral nerve blocks prolongs sensory blockade in comparison with nerve stimulator guid...

journal_title：British journal of anaesthesia

authors： Oberndorfer U,Marhofer P,Bösenberg A,Willschke H,Felfernig M,Weintraud M,Kapral S,Kettner SC

更新日期：2007-06-01 00:00:00

abstract：:A 72-yr-old patient was to undergo a left lumbar plexus block by the posterior approach to achieve postoperative analgesia after hip replacement. The block failed after three unsuccessful attempts to identify nerve structures and a fascia iliaca compartment block was performed. Postoperatively the patient received eno...

journal_title：British journal of anaesthesia

authors： Aveline C,Bonnet F

更新日期：2004-10-01 00:00:00

abstract：:We studied 40 elderly patients undergoing cataract surgery. Ten non-insulin-dependent diabetes mellitus (NIDDM) patients received standardized general anaesthesia, 10 NIDDM patients received local anaesthesia using retrobulbar block, 10 non-diabetic control patients received general anaesthesia and 10 non-diabetic con...

journal_title：British journal of anaesthesia

authors： Barker JP,Robinson PN,Vafidis GC,Burrin JM,Sapsed-Byrne S,Hall GM

更新日期：1995-05-01 00:00:00

abstract：:The effects of physostigmine 1 mg i.v. were studied on the analgesia, sedation and reduction in respiratory rate induced by morphine 10 mg/60 kg i.v. in 10 patients recovering from surgery. Within 5-10 min, physostigmine abolished the somnolent effect of morphine and restored the respiratory rate to pre-drug values. A...

journal_title：British journal of anaesthesia

authors： Weinstock M,Davidson JT,Rosin AJ,Schnieden H

更新日期：1982-04-01 00:00:00

abstract：:Successful tracheal intubation with the flexible fibreoptic bronchoscope requires a certain amount of skill which is acquired by practice. It has been suggested that the new Bullard laryngoscope may be mastered more easily. To determine if learning was superior with a flexible fibreoptic or the Bullard device, the eas...

journal_title：British journal of anaesthesia

authors： Dyson A,Harris J,Bhatia K

更新日期：1990-08-01 00:00:00

abstract：:We report a case of massive pulmonary embolism occurring at the time of graft reperfusion in a patient undergoing orthotopic liver transplantation. The clinical diagnosis of pulmonary embolus was aided by on-table echocardiography. Cardiopulmonary bypass and surgical embolectomy prevented her death. We discuss the dif...

journal_title：British journal of anaesthesia

authors： Manji M,Isaac JL,Bion J

更新日期：1998-05-01 00:00:00

abstract：:We studied the interactive effect of dexmedetomidine and morphine on gastric emptying and gastrointestinal transit in the rat. In one group of rats, to examine the interactive effect on gastrointestinal transit, the two drugs were injected i.p. in a fixed ratio (30: 1)--that of their ED50 values--in six doses (0.062-1...

journal_title：British journal of anaesthesia

authors： Asai T,Mapleson WW,Power I

更新日期：1998-01-01 00:00:00

abstract：:One hundred patients presenting for surgical treatment of fractured neck of femur were allocated to receive either spinal (SAB) or general (GA) anaesthesia. Before operation, the mean PaO2 was 9.04 kPa. There was a significant decrease in PaO2 of 0.68 kPa in GA group at 1 h after operation, while blood-gas values were...

journal_title：British journal of anaesthesia

authors： McKenzie PJ,Wishart HY,Dewar KM,Gray I,Smith G

更新日期：1980-01-01 00:00:00

abstract：:To understand the cellular and molecular basis of the anaesthetic state, it is important to remember that, in the intact CNS, synapses operate within elaborate nerve networks. From the data presented above, it is evident that block of impulse conduction in presynaptic fibres does not explain the effects of most anesth...

journal_title：British journal of anaesthesia

authors： Pocock G,Richards CD

更新日期：1993-07-01 00:00:00

abstract：:Gastric pH and volume were measured in 87 patients who had received i.v. omeprazole (a new gastric antisecretory agent) 40 mg or placebo 1 or 3 h before surgery. Omeprazole increased the pH of gastric contents in the majority of patients. Administration 1 h before surgery produced greater gastric pH and smaller volume...

journal_title：British journal of anaesthesia

authors： Cruickshank RH,Morrison DA,Bamber PA,Nimmo WS

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:The elderly are perceived as a high-risk group for procedural sedation. Concern exists regarding the safety of sedation of this patient group by emergency physicians, particularly when using propofol. METHODS:We analysed prospectively collected data on patients aged 75 yr or older undergoing sedation betwee...

journal_title：British journal of anaesthesia

authors： Homfray G,Palmer A,Grimsmo-Powney H,Appelboam A,Lloyd G

更新日期：2018-12-01 00:00:00

abstract：:The efficacy of nitroglycerine, verapamil and nifedipine in controlling post-sternotomy hypertension was compared in four groups of 20 patients anaesthetized with fentanyl 100 micrograms kg-1 undergoing elective coronary artery surgery. Vasodilators were started before surgery and adjusted to maintain systolic arteria...

journal_title：British journal of anaesthesia

authors： van Wezel HB,Bovill JG,Schuller J,Gielen J,Hoeneveld MH

更新日期：1986-03-01 00:00:00

abstract：:Studies with an emulsion formulation of ICI 35 868 (2,6- diisopropylphenol ) indicate that this new formulation has anaesthetic properties in rats and mice, and haemodynamic effects in the mini-pig which are similar to those of the previously available Cremophor formulation. Administration of the emulsion formulation ...

journal_title：British journal of anaesthesia

authors： Glen JB,Hunter SC

更新日期：1984-06-01 00:00:00

abstract：:To assess the usefulness of the Gram stain in the early diagnosis of ventilator-associated pneumonia (VAP), we performed 146 protected specimen brushings (PSB) and bronchoalveolar lavages (BAL) in 118 patients suspected of having nosocomial pneumonia. Gram stain and counts of infected cells were performed in all sampl...

journal_title：British journal of anaesthesia

authors： Allaouchiche B,Jaumain H,Chassard D,Boulétreau P

更新日期：1999-12-01 00:00:00

abstract：:Gas injection systems used in several techniques of ventilation cause increases in airway pressure and physiological changes which are frequently overlooked. The momentum flux theory describes such phenomena most appropriately. We have defined and measured the characteristics of such increases in airway pressure, usin...

journal_title：British journal of anaesthesia

authors： Isabey D,Boussignac G,Harf A

更新日期：1989-01-01 00:00:00

abstract：:Postoperative management following major surgery in patients with neuromuscular disorders associated with scoliosis is frequently complicated by sputum retention and ventilatory failure. This report demonstrates the successful perioperative management of an 11-yr-old boy with type II spinal muscular atrophy undergoing...

journal_title：British journal of anaesthesia

authors： Marchant WA,Fox R

更新日期：2002-10-01 00:00:00

abstract：:In order to clarify the relative contribution of hepatic metabolism to the short term disposition of methohexitone, we have measured hepatic blood flow during induction of anaesthesia with a 1.5-mg kg-1 i.v. bolus dose of methohexitone. Median hepatic clearance was 1.01 litre min-1 and hepatic extraction 87%. As a con...

journal_title：British journal of anaesthesia

authors： Lange H,Stephan H,Brand C,Zielmann S,Sonntag H

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Pressures (Pe) exerted by bronchial blockers on the inner wall of the bronchi may cause mucosal ischaemia. Our aims were as follows: (i) to compare the intracuff pressure (Pi) and Pe exerted by commercially available bronchial blockers in an in vitro and an ex vivo model; (ii) to investigate the influence of...

journal_title：British journal of anaesthesia

authors： Carassiti M,Mattei A,Pizzo CM,Vallone N,Saccomandi P,Schena E

更新日期：2016-09-01 00:00:00

abstract：:A variant of a rebreathing/indicator-dilution technique was used to measure lung volume. Two or three indicators, which should have essentially the same pulmonary volume of distribution, were used. Gas compositions were measured by respiratory mass spectrometry and an extrapolation was used to allow for oxygen consump...

journal_title：British journal of anaesthesia

authors： Black AM,Hahn CE,Maynard P,Scott IL

更新日期：1984-03-01 00:00:00

abstract：:Single dose-response curves were determined for suxamethonium in neonates, infants and children during thiopentone-fentanyl-nitrous oxide anaesthesia. During onset of neuromuscular block, suxamethonium produced an increase in muscle tone which was greatest in neonates and infants. The dose-response curves for the thre...

journal_title：British journal of anaesthesia

authors： Meakin G,McKiernan EP,Morris P,Baker RD

更新日期：1989-06-01 00:00:00

abstract：:A 4-year-old girl developed severe hepatitis following the fourth administration of halothane in a period of 5 months. She was shown to have a circulating antibody which acted specifically against rabbit hepatocyte previously sensitized to halothane. The patient made a full recovery from the hepatitis, but 5 months la...

journal_title：British journal of anaesthesia

authors： Lewis RB,Blair M

更新日期：1982-03-01 00:00:00