Effect of i.v. omeprazole on the pH and volume of gastric contents before surgery.

Abstract:

:Gastric pH and volume were measured in 87 patients who had received i.v. omeprazole (a new gastric antisecretory agent) 40 mg or placebo 1 or 3 h before surgery. Omeprazole increased the pH of gastric contents in the majority of patients. Administration 1 h before surgery produced greater gastric pH and smaller volume than administration 3 h before surgery. There was a reduction in the number of patients with a pH of less than 2.5 and a volume of 25 ml or more in the treated groups compared with the combined placebo groups. Omeprazole may have a role in prophylaxis against acid aspiration syndrome.

journal_name

Br J Anaesth

authors

Cruickshank RH,Morrison DA,Bamber PA,Nimmo WS

doi

10.1093/bja/63.5.536

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

536-40

issue

5

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)38702-0

journal_volume

63

pub_type

临床试验,杂志文章,随机对照试验
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    doi:10.1093/bja/58.1.111

    authors: Chandler M,Crawley BE

    更新日期:1986-01-01 00:00:00

  • Relationship between resonance and gas exchange during high frequency jet ventilation.

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    doi:10.1093/bja/64.4.453

    authors: Lin ES,Jones MJ,Mottram SD,Smith BE,Smith G

    更新日期:1990-04-01 00:00:00

  • Abstaining from cigarette smoking has no major effect on gastric emptying in habitual smokers.

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    journal_title:British journal of anaesthesia

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    doi:10.1093/bja/57.11.1104

    authors: Petring OU,Adelhøj B,Ibsen M,Brynnum J,Poulsen HE

    更新日期:1985-11-01 00:00:00

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/56.3.215

    authors: Drummond GB

    更新日期:1984-03-01 00:00:00

  • Noninvasive continuous cardiac output monitoring in perioperative and intensive care medicine.

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    更新日期:2015-04-01 00:00:00

  • Prospective study of device-related complications in intensive care unit detected by virtual autopsy.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2018.02.031

    authors: Wichmann D,Heinemann A,Zähler S,Vogel H,Höpker W,Püschel K,Kluge S

    更新日期:2018-06-01 00:00:00

  • Effects of thoracic epidural anaesthesia on microvascular gastric mucosal oxygenation in physiological and compromised circulatory conditions in dogs.

    abstract:BACKGROUND:The effects of thoracic epidural anaesthesia (TEA) on gastric mucosal microvascular haemoglobin oxygenation (microHbO(2)) are unclear. At the splanchnic level, reduction of sympathetic tone may promote vasodilation and increase microHbO(2). However, these splanchnic effects are counteracted by systemic effec...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeh235

    authors: Schwarte LA,Picker O,Höhne C,Fournell A,Scheeren TW

    更新日期:2004-10-01 00:00:00

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/bja/aer200

    authors: Arzola C,Wieczorek PM

    更新日期:2011-09-01 00:00:00

  • Third-generation FloTrac/Vigileo does not reliably track changes in cardiac output induced by norepinephrine in critically ill patients.

    abstract:BACKGROUND:The ability of the third-generation FloTrac/Vigileo software to track changes in cardiac index (CI) induced by volume expansion and norepinephrine in critically ill patients is unknown. METHODS:In subjects with circulatory failure, we administered volume expansion (20 subjects) and increased (20 subjects) o...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer491

    authors: Monnet X,Anguel N,Jozwiak M,Richard C,Teboul JL

    更新日期:2012-04-01 00:00:00

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    abstract:BACKGROUND:Moderate to deep sedation has been recommended during endoscopic submucosal dissection (ESD). However, it is often accompanied by adverse events such as respiratory depression or aspiration pneumonia. This study investigated the respiratory complications and ESD outcomes of two sedation protocols: moderate s...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeu555

    authors: Yoo YC,Park CH,Shin S,Park Y,Lee SK,Min KT

    更新日期:2015-07-01 00:00:00

  • Sex and oestrous cycle differences in visceromotor responses and vasopressin release in response to colonic distension in male and female rats anaesthetized with halothane.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/85.6.907

    authors: Holdcroft A,Sapsed-Byrne S,Ma D,Hammal D,Forsling ML

    更新日期:2000-12-01 00:00:00

  • Diazepam: routes of administration and rate of absorption. A study of women with pre-eclampsia.

    abstract::Plasma diazepam concentrations were determined following oral, i.m. and i.v. administration to a group of pregnant women with pre-eclampsia and a group of normal pregnant women. Diazepam concentrations were greater following oral as compared with i.m. administration in the control group, who received a single 5-mg dos...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/48.11.1091

    authors: Sturdee DW

    更新日期:1976-11-01 00:00:00

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/50.8.735

    authors: Jones JG,Graf PD,Lemen R

    更新日期:1978-08-01 00:00:00

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    abstract::Bupivacaine is used widely as a local anaesthetic but has potential for severe cardiovascular and central nervous system (CNS) toxicity. It has an asymmetric carbon atom giving it a chiral centre, and the commercial preparation is a racemic mixture of its two enantiomers: dextro or R(+)-bupivacaine and levo or S(-)-bu...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/80.5.594

    authors: Cox CR,Checketts MR,Mackenzie N,Scott NB,Bannister J

    更新日期:1998-05-01 00:00:00

  • New drugs and technologies, intravenous anaesthesia is on the move (again).

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aeq190

    authors: Sneyd JR,Rigby-Jones AE

    更新日期:2010-09-01 00:00:00

  • The entrapped central venous catheter.

    abstract::The central venous catheter (CVC) is associated with numerous complications more so during the process of insertion. We report for the first time how an indwelling catheter was entrapped by a replacement catheter on the same side, after being speared by the introducer needle and guidewire. The diagnosis was made when ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/ael286

    authors: Dhanani J,Senthuran S,Olivotto R,Boots RJ,Lipman J

    更新日期:2007-01-01 00:00:00

  • Transoesophageal echocardiographic monitoring of pulmonary venous obstruction induced by sternotomy closure during infant heart transplantation.

    abstract::A case of an infant receiving orthotopic heart transplantation with over-sized donor heart was reported. Left lower pulmonary venous obstruction after sternotomy closure was detected by transoesophageal echocardiography (TOE) and the decision to delay sternal closure was made and the clinical outcome was very satisfac...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/88.4.590

    authors: Lin CP,Chan KC,Chou YM,Wang MJ,Tsai SK

    更新日期:2002-04-01 00:00:00

  • Role of the massive transfusion protocol in the management of haemorrhagic shock.

    abstract::The concept of rapid delivery of multiple blood products to the bedside of a massively haemorrhaging patient seems to be a logical approach to the management of the massively bleeding patient. However, controversy exists in the use of fixed blood component ratios. Assessing the extent of the coagulopathy through point...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aeu379

    authors: Waters JH

    更新日期:2014-12-01 00:00:00

  • Influence of cuff volume on oropharyngeal leak pressure and fibreoptic position with the laryngeal mask airway.

    abstract::We studied the size 4 laryngeal mask airway (LMA) to test the hypothesis that oropharyngeal leak pressure and fibreoptic position improves with increasing cuff volume. After LMA insertion, 50 anaesthetized adult patients had the cuff inflated in 5-ml increments to 40 ml. Oropharyngeal leak pressure was optimal at 15 m...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/81.2.186

    authors: Keller C,Pühringer F,Brimacombe JR

    更新日期:1998-08-01 00:00:00

  • IV fluids and minor gynaecological surgery: effect on recovery from anaesthesia.

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    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/68.6.576

    authors: Ooi LG,Goldhill DR,Griffiths A,Smith C

    更新日期:1992-06-01 00:00:00

  • What do recent human studies tell us about the association between anaesthesia in young children and neurodevelopmental outcomes?

    abstract::Anaesthetic and sedative drugs transiently disrupt normal neural activity to facilitate healthcare procedures in children, but they can also cause long-term brain injury in experimental animal models. The US Food and Drug Administration (FDA) has recently advised that repeated or lengthy exposures to anaesthetic and s...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aex141

    authors: O'Leary JD,Warner DO

    更新日期:2017-09-01 00:00:00

  • A measure of consciousness and memory during isoflurane administration: the coherent frequency.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/71.5.633

    authors: Munglani R,Andrade J,Sapsford DJ,Baddeley A,Jones JG

    更新日期:1993-11-01 00:00:00

  • Cytotoxicity of i.v. anaesthetic agents on the isolated rat hepatocyte.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/51.8.733

    authors: Sear JW,McGivan JD

    更新日期:1979-08-01 00:00:00

  • Impaired endothelial function after aneurysmal subarachnoid haemorrhage correlates with arginine:asymmetric dimethylarginine ratio.

    abstract:BACKGROUND:Endothelial dysfunction might be involved in the development of cerebral vasospasm after aneurysmal subarachnoid haemorrhage (SAH). METHODS:This prospective observational study of 48 SAH subjects and 23 control subjects examined associations between reactive hyperaemia index (RHI) measured by peripheral art...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aet331

    authors: Bergström A,Staalsø JM,Romner B,Olsen NV

    更新日期:2014-02-01 00:00:00

  • Regurgitation of gastric contents during general anaesthesia using the laryngeal mask airway.

    abstract::We have investigated the incidence of regurgitation of gastric contents during general anaesthesia administered via a laryngeal mask airway (LMA) or face mask and Guedel airway in 56 patients with no risk factors for regurgitation. Patients swallowed a gelatin capsule containing methylene blue 10 min before induction ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/69.3.314

    authors: Barker P,Langton JA,Murphy PJ,Rowbotham DJ

    更新日期:1992-09-01 00:00:00

  • A sheep preparation for studying interactions between blood flow and drug disposition. IV: The effects of general and spinal anaesthesia on blood flow and cefoxitin disposition.

    abstract::Control measurements of blood flow through and cefoxitin extraction ratios across heart and lungs, liver, kidneys and gut were made under steady-state conditions in awake unrestrained sheep. The studies then were repeated with the same animals anaesthetized with 1.5% halothane or whilst undergoing high thoracic (to ap...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/57.12.1239

    authors: Runciman WB,Mather LE,Ilsley AH,Carapetis RJ,Upton RN

    更新日期:1985-12-01 00:00:00

  • Mivacurium compared with succinylcholine in children with liver disease.

    abstract::We have compared mivacurium and succinylcholine in 27 paediatric patients with mild (Child's A) to moderate (Child's B) liver disease undergoing oesophagogastroduodenoscopy (OGD) and injection of oesophageal varices, with 10 healthy children receiving mivacurium for ENT procedures. With mivacurium 0.2 mg kg-1, the sev...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/81.3.463

    authors: Green DW,Fisher M,Sockalingham I

    更新日期:1998-09-01 00:00:00

  • Feasibility of measuring memory response to increasing dexmedetomidine sedation in children.

    abstract:BACKGROUND:The memory effect of dexmedetomidine has not been prospectively evaluated in children. We evaluated the feasibility of measuring memory and sedation responses in children during dexmedetomidine sedation for non-painful radiological imaging studies. Secondarily, we quantified changes in memory in relation to ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aew421

    authors: Mason KP,Kelhoffer ER,Prescilla R,Mehta M,Root JC,Young VJ,Robinson F,Veselis RA

    更新日期:2017-02-01 00:00:00

  • Review of perioperative falls.

    abstract::Falls are a known public health problem, and there is increasing recognition of the importance of perioperative falls for risk prediction and quality assessment. Our objective was to review existing literature regarding the occurrence, injuries, and risk factors of preoperative and postoperative falls. A systematized ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aew377

    authors: Kronzer VL,Wildes TM,Stark SL,Avidan MS

    更新日期:2016-12-01 00:00:00

  • Effect of propofol on heart rate, arterial pressure and digital plethysmograph variability.

    abstract::We have investigated the effects of propofol on beat-to-beat fluctuations in heart rate, arterial pressure (continuous arterial tonometry) and infrared finger plethysmography in 10 healthy male patients undergoing elective surgery. Administration of Diprivan (propofol 10 mg ml-1) 0.2 ml kg-1, followed by an infusion o...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/73.2.167

    authors: Robinson BJ,Buyck HC,Galletly DC

    更新日期:1994-08-01 00:00:00