Sex and oestrous cycle differences in visceromotor responses and vasopressin release in response to colonic distension in male and female rats anaesthetized with halothane.

abstract：:By analysing the EEG, reticular multi-unit activity and behavioural changes, we have classified general anaesthetics into three groups: central nervous system (CNS) depressant, CNS excitant and epileptogenic agents. Changes in CNS neural activity are associated with alteration in transmitter release. We have attempted...

journal_title：British journal of anaesthesia

authors： Shichino T,Murakawa M,Adachi T,Arai T,Miyazaki Y,Mori K

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) may affect blood coagulation. We studied the effects of a modified, balanced, high-molecular weight [mean molecular weight (MW) 550 kDa], high-substituted [degree of substitution (DS) 0.7] HES preparation (Hextend) on coagulation in patients undergoing major abdominal surgery. METH...

journal_title：British journal of anaesthesia

authors： Boldt J,Haisch G,Suttner S,Kumle B,Schellhaass A

更新日期：2002-11-01 00:00:00

abstract：:In a prospective, randomized, double-blind clinical study, we have studied 100 children, aged 2-12 yr, to compare halothane and sevoflurane in outpatient dental anaesthesia. All patients were unpremedicated and received inhalation induction using nitrous oxide in oxygen supplemented with either halothane (maximum insp...

journal_title：British journal of anaesthesia

authors： Paris ST,Cafferkey M,Tarling M,Hancock P,Yate PM,Flynn PJ

更新日期：1997-09-01 00:00:00

abstract：:It is generally accepted that halothane reduces airway and tissue resistance in lungs with preexisting airway tone. However, under conditions of resting airway tone, pulmonary resistance remains unaltered. In this study, we have determined the effects of halothane on respiratory system, pulmonary and chest wall resist...

journal_title：British journal of anaesthesia

authors： Reta GS,Riva JA,Piriz H,Medeiros AS,Rocco PR,Zin WA

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The minimum alveolar concentration (MAC) is a traditional index of the hypnotic potency of an inhalational anaesthetic. To investigate the anaesthetic as well as the unwanted effects of xenon (Xe) in a swine model, it is useful to know MAC(Xe). METHODS:The study was performed using ten swine (weight 27.8-35...

journal_title：British journal of anaesthesia

authors： Hecker KE,Horn N,Baumert JH,Reyle-Hahn SM,Heussen N,Rossaint R

更新日期：2004-03-01 00:00:00

abstract：:Gastric pH and volume were measured in 87 patients who had received i.v. omeprazole (a new gastric antisecretory agent) 40 mg or placebo 1 or 3 h before surgery. Omeprazole increased the pH of gastric contents in the majority of patients. Administration 1 h before surgery produced greater gastric pH and smaller volume...

journal_title：British journal of anaesthesia

authors： Cruickshank RH,Morrison DA,Bamber PA,Nimmo WS

更新日期：1989-11-01 00:00:00

abstract：:Eight patients with a history of failed tracheal intubation during pregnancy were investigated by x-ray laryngoscopy after delivery. Partial elevation of the epiglottis with no view of glottic structures was found in five patients who were therefore considered to still present difficulty. In each of these five patient...

journal_title：British journal of anaesthesia

authors： Fahy L,Horton WA,Charters P

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients after major surgery. An association between POCD and the development of dementia has been suspected. In this study, we assessed if POCD was a risk factor for the occurrence of dementia. METHODS:Danish patients enrolled b...

journal_title：British journal of anaesthesia

authors： Steinmetz J,Siersma V,Kessing LV,Rasmussen LS,ISPOCD Group.

更新日期：2013-06-01 00:00:00

abstract：:Mice, previously immunized with sheep erythrocytes, were anaesthetized with halothane and the splenic lymphoid cells were incubated with 3H-thymidine at 1-h intervals. Abiphasic response was observed; 0.9 and 1.5% halothane reduced 3H-thymidine incorporation into the primed lymphoid cells by 83 and 94% respectively, w...

journal_title：British journal of anaesthesia

authors： Bandoh T,Fujita T

更新日期：1976-12-01 00:00:00

abstract：:Abnormal oxygen use and organ failure in the critically ill may result from 'poisoning' of mitochondrial function. Measurement of arterial ketone body ratio (AKBR) has been proposed to reflect mitochondrial redox state and may provide a useful marker to monitor mitochondrial function in the critically ill. We measured...

journal_title：British journal of anaesthesia

authors： Yassen KA,Galley HF,Lee A,Webster NR

更新日期：1999-08-01 00:00:00

abstract：:We report the successful preoperative control and anaesthetic management of severe hypertension in a 7-month-old baby with nephroblastoma and increased renin activity. The strategy for selection of appropriate antihypertensive pharmacological agents and the anaesthetic implications and management of the condition are ...

journal_title：British journal of anaesthesia

authors： Charlton GA,Sedgwick J,Sutton DN

更新日期：1992-08-01 00:00:00

abstract：:NHS Blood and Transplant (NHSBT) was established in 2005 as a Special Health Authority when the National Blood Authority and UK Transplant merged. This helped to bring tissue banking and organ transplantation services under one umbrella organization. This merger means that ~!95% of all deceased donors (whether tissue,...

journal_title：British journal of anaesthesia

authors： Gaum L,Reynolds I,Jones MN,Clarkson AJ,Gillan HL,Kaye SB

更新日期：2012-01-01 00:00:00

abstract：:The pharmacokinetics of propofol in a dose of 2.5 mg kg-1 given via a vein in the antecubital fossa were studied in 18 patients. Anaesthesia was maintained with nitrous oxide in oxygen in all patients. The effects of pretreatment with fentanyl (n = 6) and maintenance with halothane (n = 6) on the pharmacokinetics of p...

journal_title：British journal of anaesthesia

authors： Cockshott ID,Briggs LP,Douglas EJ,White M

更新日期：1987-09-01 00:00:00

abstract：:The effects of diazepam, which acts at GABAA receptors to enhance the effects of GABA, and ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, on local rates of cerebral glucose utilization (ICMRglc) were examined in unrestrained rats. Four groups were studied: vehicle-injected controls; and ketamine...

journal_title：British journal of anaesthesia

authors： Eintrei C,Sokoloff L,Smith CB

更新日期：1999-04-01 00:00:00

abstract：:Dose-duration relationships for vecuronium were determined and the duration of action produced by vecuronium 0.3 mg kg-1 shown to equal that of pancuronium 0.1 mg kg-1. Using these doses, the neuromuscular blocking properties and cardiovascular effects of the two drugs were compared. With large dose administration of ...

journal_title：British journal of anaesthesia

authors： Rørvik K,Husby P,Gramstad L,Vamnes JS,Bitsch-Larsen L,Koller ME

更新日期：1988-08-01 00:00:00

abstract：:Progressive obstruction of an axillary vein following an axillary approach to brachial plexus blockade is described. At surgical exploration, the axillary vein was narrowed with an aneurysm of its wall. It is likely that, during the performance of the block, the needle penetrated the adventitia of the vein, causing a ...

journal_title：British journal of anaesthesia

authors： Restelli L,Pinciroli D,Conoscente F,Cammelli F

更新日期：1984-09-01 00:00:00

abstract：:In vitro experiments on the rat phrenic nerve-hemidiaphragm preparation, stimulated directly or indirectly with supramaximal impulses at 0.1 Hz revealed that pethidine in concentrations greater than 5 micrograms ml-1 caused a rapid increase of the twitch. This was maximal (60% increase during direct and 70% increase d...

journal_title：British journal of anaesthesia

authors： Boros M,Chaudhry IA,Nagashima H,Duncalf RM,Sherman EH,Foldes FF

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Ketamine is widely used as an i.v. anaesthetic agent and as a drug of abuse. Hepatocytes contribute to the metabolism of endogenous and exogenous substances. This study evaluated the toxic effects of S-(+)-ketamine and possible mechanisms using human hepatoma HepG2 cells as the experimental model. METHODS:H...

journal_title：British journal of anaesthesia

authors： Lee ST,Wu TT,Yu PY,Chen RM

更新日期：2009-01-01 00:00:00

abstract：:Both the performance of breathing systems and recommendations for the fresh gas flows to be used in patients breathing spontaneously can be expressed in ml kg-1 min-1 or fresh gas: total ventilation ratio (VF:VE). We have examined the relationship between these two descriptions. The data of 106 subjects (awake volunte...

journal_title：British journal of anaesthesia

authors： Soni N,Ooi R

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The observation that patients presenting for bariatric surgery had a high incidence of neuromuscular blocking agent (NMBA) anaphylaxis prompted this restricted case-control study to test the hypothesis that obesity is a risk factor for NMBA anaphylaxis, independent of differences in pholcodine consumption. ...

journal_title：British journal of anaesthesia

authors： Sadleir PHM,Clarke RC,Goddard CE,Day C,Weightman W,Middleditch A,Platt PR

更新日期：2021-01-13 00:00:00

abstract：:A series of 443 spinal anaesthetics is described. The procedures included operative vaginal delivery, removal of retained placenta and a miscellaneous group common to most obstetric units. Failure to provide effective relief of pain occurred in 5.2% of patients. There was one potentially serious complication, but with...

journal_title：British journal of anaesthesia

authors： Crawford JS

更新日期：1979-06-01 00:00:00

abstract：:Five-year survival following cardiac transplantation approaches 50% and such patients occasionally present for non-cardiac surgery. The application of a simple general anaesthetic technique is described in a patient undergoing minor surgery, and the problems involved in managing heart transplant recipients are discuss...

journal_title：British journal of anaesthesia

authors： Bricker SR,Sugden JC

更新日期：1985-06-01 00:00:00

abstract：:This case report outlines the clinical process whereby a patient with severe traumatic brain injury became a non-heartbeating organ donor after a withdrawal-of-care decision. This process raises a series of ethical questions regarding decision-making on grounds of futility, the role of the next of kin, informed consen...

journal_title：British journal of anaesthesia

authors： Bell MD

更新日期：2005-04-01 00:00:00

abstract：:Hypertensive patients were monitored for myocardial ischaemia during anaesthesia and surgery with the V5 lead of a standard electrocardiograph. Myocardial ischaemia was detected in 11 of 39 untreated hypertensive patients and in four of seven receiving therapy with a diuretic, but in none of 44 receiving atenolol. Fou...

journal_title：British journal of anaesthesia

authors： Stone JG,Foëx P,Sear JW,Johnson LL,Khambatta HJ,Triner L

更新日期：1988-12-01 00:00:00

abstract：:We tested the hypothesis that pressures exerted on the pharyngeal mucosa by the laryngeal mask airway (LMA) and cuffed oropharyngeal airway (COPA) differ, in 20 male and 20 female adult patients. Microchip pressure sensors were attached to the LMA and COPA at four similar anatomical locations (base of the tongue, late...

journal_title：British journal of anaesthesia

authors： Keller C,Brimacombe J

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The pathophysiology of the serotoninergic system in malignant hyperthermia (MH) is not completely understood. The serotonin-2 (5HT(2A)) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) induces typical MH symptoms, including skeletal muscle rigidity, an increase in body tempe...

journal_title：British journal of anaesthesia

authors： Gerbershagen MU,Wappler F,Fiege M,Kolodzie K,Weisshorn R,Szafarczyk W,Kudlik C,Schulte Am Esch J

更新日期：2003-08-01 00:00:00

abstract：:Cobra venom consists of a neurotoxin which is responsible for respiratory paralysis simulating that associated with a non-depolarizing muscle relaxant. A combination of artificial respiration and neostigmine has been useful in resuscitating a child bitten by a snake. ...

journal_title：British journal of anaesthesia

authors： Naphade RW,Shetti RN

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Early tracheostomy may decrease the duration of mechanical ventilation, sedation exposure, and intensive care stay, possibly resulting in improved clinical outcomes, but the evidence is conflicting. METHODS:Systematic review and meta-analysis of randomized trials in patients allocated to tracheostomy within...

journal_title：British journal of anaesthesia

authors： Szakmany T,Russell P,Wilkes AR,Hall JE

更新日期：2015-03-01 00:00:00

abstract：:Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system st...

journal_title：British journal of anaesthesia

authors： Fahey MR,Rupp SM,Canfell C,Fisher DM,Miller RD,Sharma M,Castagnoli K,Hennis PJ

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Interscalene brachial plexus block (ISBPB) is an effective nerve block for shoulder surgery. However, a 100% incidence of phrenic nerve palsy limits the application of ISBPB for patients with limited pulmonary reserve. We examined the incidence of phrenic nerve palsy with a low-volume ISBPB compared with a s...

journal_title：British journal of anaesthesia

authors： Riazi S,Carmichael N,Awad I,Holtby RM,McCartney CJ

更新日期：2008-10-01 00:00:00