Is postoperative cognitive dysfunction a risk factor for dementia? A cohort follow-up study.

abstract：BACKGROUND:The effects of thoracic epidural anaesthesia (TEA) on gastric mucosal microvascular haemoglobin oxygenation (microHbO(2)) are unclear. At the splanchnic level, reduction of sympathetic tone may promote vasodilation and increase microHbO(2). However, these splanchnic effects are counteracted by systemic effec...

journal_title：British journal of anaesthesia

authors： Schwarte LA,Picker O,Höhne C,Fournell A,Scheeren TW

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Some anaesthetic agents exhibit an age-dependent analgesic effect, for example nitrous oxide, which is ineffective in newborn rats. We investigated whether a similar time dependency existed for the responses to the volatile anaesthetic isoflurane. METHODS:The analgesic and hypnotic properties of isoflurane ...

journal_title：British journal of anaesthesia

authors： Sanders RD,Patel N,Hossain M,Ma D,Maze M

更新日期：2005-09-01 00:00:00

abstract：:We have examined the influence of electrical stimulation on caffeine-induced tension generation during contracture testing used to diagnose malignant hyperthermia. The cumulative contracture response to caffeine was compared in pairs of morphologically comparable muscle bundles obtained from the same patient. Only one...

journal_title：British journal of anaesthesia

authors： Heytens L,Martin JJ,Bossaert LL

更新日期：1992-07-01 00:00:00

abstract：:We describe a 25 mg intrathecal morphine overdose during a combined spinal-epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided. ...

journal_title：British journal of anaesthesia

authors： Cannesson M,Nargues N,Bryssine B,Debon R,Boselli E,Chassard D

更新日期：2002-12-01 00:00:00

abstract：:We tested the hypothesis that the solvent for etomidate was a factor in the incidence of pain and other side effects after injection, and that these were associated with histamine release. Nine of 10 volunteers who received etomidate in a propylene glycol formulation reported moderate to severe pain on injection; only...

journal_title：British journal of anaesthesia

authors： Doenicke AW,Roizen MF,Hoernecke R,Lorenz W,Ostwald P

更新日期：1999-09-01 00:00:00

abstract：:In order to clarify the relative contribution of hepatic metabolism to the short term disposition of methohexitone, we have measured hepatic blood flow during induction of anaesthesia with a 1.5-mg kg-1 i.v. bolus dose of methohexitone. Median hepatic clearance was 1.01 litre min-1 and hepatic extraction 87%. As a con...

journal_title：British journal of anaesthesia

authors： Lange H,Stephan H,Brand C,Zielmann S,Sonntag H

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The revised cardiac risk index (RCRI) is associated strongly with increased cardiac ischaemic risk and perioperative death. Associations with non-cardiac morbidity in non-cardiac surgery have not been explored. In the elective orthopaedic surgical population, morbidity is common but preoperative predictors a...

journal_title：British journal of anaesthesia

authors： Ackland GL,Harris S,Ziabari Y,Grocott M,Mythen M,SOuRCe Investigators.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The inhibitory effect of anaesthetic agents on hypoxic pulmonary vasoconstriction may depend upon their dose, especially when using a volatile agent. The aim of this randomized open study was to compare the effects of sevoflurane and propofol, as primary anaesthetic agents, on oxygenation during one-lung ven...

journal_title：British journal of anaesthesia

authors： Pruszkowski O,Dalibon N,Moutafis M,Jugan E,Law-Koune JD,Laloë PA,Fischler M

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Single preoperative gabapentinoid (gabapentin and pregabalin) administration has been associated with respiratory depression during Phase I anaesthesia recovery. In this study, we assess for associations between chronic (home) use and perioperative administration (preoperative and postoperative) of gabapenti...

journal_title：British journal of anaesthesia

authors： Deljou A,Hedrick SJ,Portner ER,Schroeder DR,Hooten WM,Sprung J,Weingarten TN

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Lower thoracic epidural anaesthesia and analgesia (EDA) has gained increasing importance in perioperative pain therapy. The loss-of-resistance technique used to identify the epidural space is thought to rely on the penetration of the ligamentum flavum. Investigations at the cervical and lumbar regions have d...

journal_title：British journal of anaesthesia

authors： Lirk P,Colvin J,Steger B,Colvin HP,Keller C,Rieder J,Kolbitsch C,Moriggl B

更新日期：2005-06-01 00:00:00

abstract：:We evaluated the use of an inexpensive trans-illuminating light wand for tracheal intubation. Expertise in its use was acquired quickly, thereby providing successful per-oral intubation in all patients who were able to open the mouth, irrespective of the view obtained of the epiglottis and larynx. ...

journal_title：British journal of anaesthesia

authors： Ainsworth QP,Howells TH

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Signalling of several G-protein-coupled receptors of the Gq/11 family is time-dependently inhibited by local anaesthetics (LAs). Since LA-induced modulation of muscarinic m1 and m3 receptor function may explain their beneficial effects in clinical practice, such as decreased postoperative cognitive dysfuncti...

journal_title：British journal of anaesthesia

authors： Picardi S,Stevens MF,Hahnenkamp K,Durieux ME,Lirk P,Hollmann MW

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The role of repeated prone positioning in intubated subjects with acute respiratory distress syndrome caused by COVID-19 remains unclear. METHODS:We conducted a retrospective observational cohort study of critically ill intubated patients with COVID-19 who were placed in the prone position between March 18,...

journal_title：British journal of anaesthesia

authors： Weiss TT,Cerda F,Scott JB,Kaur R,Sungurlu S,Mirza SH,Alolaiwat AA,Kaur R,Augustynovich AE,Li J

更新日期：2021-01-01 00:00:00

abstract：:We prospectively studied spontaneous recovery from cisatracurium-induced neuromuscular block in 18 patients scheduled for cardiac surgery, and its suitability for fast-track cardiac surgery. Neuromuscular block was induced by an i.v. bolus (range 0.15-0.3 mg kg(-1)) and maintained by a continuous infusion (range 1.1-3...

journal_title：British journal of anaesthesia

authors： Ouattara A,Richard L,Charrière JM,Lanquetot H,Corbi P,Debaene B

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Emotional information has the ability to alter the formation and strength of a memory ('memory modulation'). Memory modulation by negative emotion is mediated by the amygdala. It is not known how gamma aminobutyric acid (GABA)ergic drugs affect the processes involved in memory modulation. This study investig...

journal_title：British journal of anaesthesia

authors： Pryor KO,Veselis RA,Reinsel RA,Feshchenko VA

更新日期：2004-09-01 00:00:00

abstract：:In a random, double-blind crossover trial using an ischaemic limb pain model we have assessed the speed of onset of analgesia after an i.v. bolus of equipotent doses of diamorphine and morphine in 12 healthy male volunteers. Pain and its subsequent relief were assessed by means of a visual analogue scale. Two of the s...

journal_title：British journal of anaesthesia

authors： Morrison LM,Payne M,Drummond GB

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Magnesium is a calcium and an NMDA-receptor antagonist and can modify important mechanisms of nociception. We evaluated the co-analgesic effect of magnesium in the postoperative setting after on-pump cardiac surgery. METHODS:Forty patients randomly received either magnesium gluconate as an i.v. bolus of 0.2...

journal_title：British journal of anaesthesia

authors： Steinlechner B,Dworschak M,Birkenberg B,Grubhofer G,Weigl M,Schiferer A,Lang T,Rajek A

更新日期：2006-04-01 00:00:00

abstract：:Abnormal oxygen use and organ failure in the critically ill may result from 'poisoning' of mitochondrial function. Measurement of arterial ketone body ratio (AKBR) has been proposed to reflect mitochondrial redox state and may provide a useful marker to monitor mitochondrial function in the critically ill. We measured...

journal_title：British journal of anaesthesia

authors： Yassen KA,Galley HF,Lee A,Webster NR

更新日期：1999-08-01 00:00:00

abstract：:We report the anaesthetic management of a male neonate with congenital cyst adenoid malformation (CCAM) of the lung who underwent thoracotomy for resection of CCAM 24 h after birth and again at 24 days. The initial operation involved a 10-day admission to a paediatric intensive care unit (PICU) requiring ventilation, ...

journal_title：British journal of anaesthesia

authors： Guruswamy V,Roberts S,Arnold P,Potter F

更新日期：2005-08-01 00:00:00

abstract：:We have studied the effect of milrinone on pulmonary vascular resistance (PVR) in dogs with hypoxic pulmonary vasoconstriction (HPV). Using a pulmonary arterial occlusion method, we measured effective pulmonary capillary pressure (Pcap) by which total PVR was partitioned into arterial (PVRa) and venous (PVRv) componen...

journal_title：British journal of anaesthesia

authors： Kato R,Sato J,Nishino T

更新日期：1998-12-01 00:00:00

abstract：:We have compared the ability of naïve intubators to intubate the trachea using a laryngoscope and an intubating laryngeal mask airway (ILMA) after receiving basic training, in a randomized, prospective, crossover study in 60 patients. Ventilation of the lungs via the ILMA was also compared with ventilation with a face...

journal_title：British journal of anaesthesia

authors： Avidan MS,Harvey A,Chitkara N,Ponte J

更新日期：1999-10-01 00:00:00

abstract：:The 119 patients who had undergone previous Caesarean section lumbar extradural block was administered to 77 (65%); the other 42 (35%) received analgesia with ketobemidone 0.8-1.0 ml i.m. or nitrous oxide in oxygen intermittently, or both. Controlled i.v. infusion of oxytocin for induction or acceleration of labour wa...

journal_title：British journal of anaesthesia

authors： Carlsson C,Nybell-Lindahl G,Ingemarsson I

更新日期：1980-08-01 00:00:00

abstract：INTRODUCTION:Current guidelines suggest a fasting time of 2 h for clear fluids, which is often exceeded in clinical practice, leading to discomfort, dehydration and stressful anaesthesia induction to patients, especially in the paediatric population. Shorter fluid fasting might be a strategy to improve patient comfort ...

journal_title：British journal of anaesthesia

authors： Schmidt AR,Buehler P,Seglias L,Stark T,Brotschi B,Renner T,Sabandal C,Klaghofer R,Weiss M,Schmitz A

更新日期：2015-03-01 00:00:00

abstract：:Diltiazem inhibited and antagonized the abnormal contractures induced by halothane, caffeine and potassium chloride in isolated skeletal muscle from pigs susceptible to malignant hyperpyrexia (MHS). Contractile responses to caffeine and electrical stimulation also were suppressed by diltiazem in control tissue. Simila...

journal_title：British journal of anaesthesia

authors： Foster PS,Denborough MA

更新日期：1989-05-01 00:00:00

abstract：:We have studied in eight rabbits the cardiovascular effects of midazolam, propofol and alfentanil with graded hypoxia. Central blood volume was reduced progressively by gradual inflation of a thoracic vena cava cuff so that cardiac index (CI) decreased at a constant rate. Under control conditions the haemodynamic resp...

journal_title：British journal of anaesthesia

authors： Blake DW,Van Leeuwen AF,Petring OU,Ludbrook J,Ventura S

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The relationship between end-tidal sevoflurane concentration, bispectral index (BIS) and the EEG bispectrum in children appears to be age dependent. The aim of this study was to quantify the BIS values at 1 MAC (minimum alveolar concentration) for desflurane and halothane, and explore the relationship with a...

journal_title：British journal of anaesthesia

authors： Tirel O,Wodey E,Harris R,Bansard JY,Ecoffey C,Senhadji L

更新日期：2006-04-01 00:00:00

abstract：:Serum concentrations of the cytokine, interleukin-6 (IL-6), increase after surgical trauma. IL-6 mediates the synthesis of acute phase proteins and stimulates secretion of pituitary hormones. We have examined the time course of circulating IL-6, and cortisol and growth hormone responses in patients undergoing hysterec...

journal_title：British journal of anaesthesia

authors： Moore CM,Desborough JP,Powell H,Burrin JM,Hall GM

更新日期：1994-03-01 00:00:00

abstract：:We describe the anaesthetic management of a patient who underwent transthoracic endoscopic vagotomy. One-lung ventilation was necessary to provide adequate surgical access. Potential intraoperative problems involved arterial oxygen saturation during one-lung ventilation, unequal intrathoracic pressures causing mediast...

journal_title：British journal of anaesthesia

authors： Chui PT,Gin T,Chung SC

更新日期：1992-03-01 00:00:00

abstract：:We have compared, in a double-blind study, the efficacy of flumazenil with that of aminophylline in antagonizing the effects of midazolam in 60 patients (ASA I-II, mean age 66 yr) undergoing transurethral resection of prostate under spinal anaesthesia. All patients received midazolam 0.075 mg kg-1 i.v. and the test dr...

journal_title：British journal of anaesthesia

authors： Sibai AN,Sibai AM,Baraka A

更新日期：1991-05-01 00:00:00

abstract：:In rats injected s.c. with formalin, behavioural correlates of the amount and pattern of Fos-like immunoreactivity (Fos-Ll) (molecular responses to pain) were studied to test if early phase treatment with 75% nitrous oxide or 2% halothane, or both, suppressed subsequent spinal sensitization. Rats were allocated to fou...

journal_title：British journal of anaesthesia

authors： Sun WZ,Shyu BC,Shieh JY

更新日期：1996-01-01 00:00:00