Isoflurane exerts antinociceptive and hypnotic properties at all ages in Fischer rats.

abstract：:A patient with Ebstein's anomaly undergoing anaesthesia for the operation of hysterectomy is reported. The considerations relating to the risk of an increased right-to-left intracardiac shunt are discussed. The patient was anaesthetized successfully with a combination of nitrous oxide, droperidol and fentanyl. ...

journal_title：British journal of anaesthesia

authors： Bengtsson IM,Magno R,Wickström I

更新日期：1977-05-01 00:00:00

abstract：:In 15 patients (ASA I-II) undergoing intraabdominal gynaecological surgery, muscle paralysis for tracheal intubation and surgery was achieved by a combined bolus and demand infusion of vecuronium. The initial loading dose of 67 micrograms kg-1 and the rate of subsequent infusion were determined by evaluation of the ta...

journal_title：British journal of anaesthesia

authors： Haraldsted VY,Nielsen JW,Joensen F,Dilling-Hansen B,Hasselstrøm L

更新日期：1988-10-01 00:00:00

abstract：:The effect of pretreatment with suxamethonium, gallamine or pancuronium on suxamethonium-induced fasciculations and myalgia was studied in a controlled, randomized and double-blind clinical trial. Both fasciculations and myalgia were assessed on a four-point rating scale. There was no significant correlation between f...

journal_title：British journal of anaesthesia

authors： O'Sullivan EP,Williams NE,Calvey TN

更新日期：1988-03-01 00:00:00

abstract：:Seventeen patients received morphine 0.2 mgkg-1 in a 10% dextrose solution i.m. (n = 5), extradurally (n = 6) and intrathecally (n = 6) for pain after operation. Morphine was measured in plasma by radioimmunoassay. Plasma immunoreactive morphine concentration was significantly less after intrathecal administration aft...

journal_title：British journal of anaesthesia

authors： Chauvin M,Samii K,Schermann JM,Sandouk P,Bourdon R,Viars P

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:The perioperative period may be associated with a marked neurohumoral stress response, significant fluid losses, and varied fluid replacement regimes. Acute changes in serum sodium concentration are therefore common, but predictors and outcomes of these changes have not been investigated in a large surgical ...

journal_title：British journal of anaesthesia

authors： Klinck J,McNeill L,Di Angelantonio E,Menon DK

更新日期：2015-04-01 00:00:00

abstract：:Thirteen of 31 Belgian Landrace pigs developed malignant hyperthermia (MH) after breathing halothane. A short period of exercise 1 h before the administration of the triggering agent increased the incidence of the syndrome to 100% in eight similar pigs. Clinical symptoms were more marked and developed more rapidly in ...

journal_title：British journal of anaesthesia

authors： van den Hende C,Lister D,Muylle E,Ooms L,Oyaert W

更新日期：1976-09-01 00:00:00

abstract：:One hundred patients presenting for surgical treatment of fractured neck of femur were allocated to receive either spinal (SAB) or general (GA) anaesthesia. Before operation, the mean PaO2 was 9.04 kPa. There was a significant decrease in PaO2 of 0.68 kPa in GA group at 1 h after operation, while blood-gas values were...

journal_title：British journal of anaesthesia

authors： McKenzie PJ,Wishart HY,Dewar KM,Gray I,Smith G

更新日期：1980-01-01 00:00:00

abstract：:The relative analgesic efficacy and side-effect profile of peripheral nerve blockade (PNB) techniques compared with lumbar epidural analgesia for major knee surgery is unclear. We undertook a systematic review and meta-analysis of all randomized trials comparing epidural analgesia with PNB for major knee surgery. Eigh...

journal_title：British journal of anaesthesia

authors： Fowler SJ,Symons J,Sabato S,Myles PS

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Tobacco use interventions in surgical patients who smoke could benefit both their short-term outcome and long-term health. Anaesthesiologists and surgeons can play key roles in delivering these interventions. This study determined the practices, attitudes, and beliefs of these physicians regarding tobacco us...

journal_title：British journal of anaesthesia

authors： Kai T,Maki T,Takahashi S,Warner DO

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Echocardiography has been shown to positively impact on the management of the critically ill patient. However, many published studies have a significant bias towards inclusion of cardiothoracic patients. We present an audit of the impact of echocardiography on the management of patients in a district general...

journal_title：British journal of anaesthesia

authors： Orme RM,Oram MP,McKinstry CE

更新日期：2009-03-01 00:00:00

abstract：:A new design of tracheal tube cuff was compared with two types of high-volume, low-pressure (HVLP) cuffed tracheal tube for leakage of fluid from the subglottic space into the trachea. Spontaneous and positive-pressure ventilation were simulated using a mechanical lung, an intubated model trachea and a ventilator. Exc...

journal_title：British journal of anaesthesia

authors： Young PJ,Ridley SA,Downward G

更新日期：1998-06-01 00:00:00

abstract：:Magnesium inhibits the release of acetylcholine from the motor nerve terminal and thus potentiates the action of the non-depolarizing neuromuscular blocking drugs. We have examined the possibility that this effect might enhance the speed of onset of non-depolarizing block with pancuronium. Following the administration...

journal_title：British journal of anaesthesia

authors： James MF,Schenk PA,van der Veen BW

更新日期：1991-02-01 00:00:00

abstract：:Use of inhaled nitric oxide for treatment of pulmonary hypertension in adult critical illness is limited by its mode of delivery and high costs, prompting evaluation of alternative therapies. We report the use of oral sildenafil in a patient with severe secondary pulmonary hypertension and right ventricular dysfunctio...

journal_title：British journal of anaesthesia

authors： Ng J,Finney SJ,Shulman R,Bellingan GJ,Singer M,Glynne PA

更新日期：2005-06-01 00:00:00

abstract：:The relative sensitivity of sympathetic preganglionic and postganglionic axons, B and C fibres, respectively, to two structurally dissimilar local anaesthetics was examined. The concentration of amethocaine (ester-linked tertiary amine) or prilocaine (amide-linked secondary amine) required to reduce the B fibre compou...

journal_title：British journal of anaesthesia

authors： Scurlock JE,Heavner JE,de Jong RH

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Malposition of tracheostomy tubes is difficult to detect at the bedside and may contribute to eventual device misplacement. Endoscopic examination can be undertaken via tracheoscopic (T-view) or trans-laryngeal (L-view) approach, offering more precise detail regarding positioning within the airway. The aims ...

journal_title：British journal of anaesthesia

authors： McGrath BA,Lynch K,Templeton R,Webster K,Simpson W,Alexander P,Columb MO

更新日期：2017-01-01 00:00:00

abstract：:Protein kinase C (PKC) is a key regulatory enzyme that has been implicated as a molecular target for the action of general anaesthetics. We have determined the effects of halothane on the translocation and down-regulation of conventional PKC (cPKC) by analysing the subcellular distribution of PKC activity, [3H]phorbol...

journal_title：British journal of anaesthesia

authors： Hemmings HC Jr,Adamo AI

更新日期：1997-02-01 00:00:00

abstract：:We describe a 25 mg intrathecal morphine overdose during a combined spinal-epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided. ...

journal_title：British journal of anaesthesia

authors： Cannesson M,Nargues N,Bryssine B,Debon R,Boselli E,Chassard D

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Cut-off points (CPs) of the numeric rating scale (NRS 0-10) are regularly used in postoperative pain treatment. However, there is insufficient evidence to identify the optimal CP between mild and moderate pain. METHODS:A total of 435 patients undergoing general, trauma, or oral and maxillofacial surgery wer...

journal_title：British journal of anaesthesia

authors： Gerbershagen HJ,Rothaug J,Kalkman CJ,Meissner W

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Increasing numbers of older patients prescribed clopidogrel are presenting for urgent hip fracture surgery. Best practice for the management of clopidogrel therapy is unknown, although delays to surgery are associated with increased mortality. We investigated the influence of perioperative management of clop...

journal_title：British journal of anaesthesia

authors： Collyer TC,Reynolds HC,Truyens E,Kilshaw L,Corcoran T

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The ultrasound cardiac output monitor (USCOM) is a continuous wave Doppler system designed to measure cardiac output (CO) non-invasively and intermittently either from the pulmonary or from the aortic valve. USCOM scan quality is critical to obtaining reliable data and during anaesthesia it is said to deteri...

journal_title：British journal of anaesthesia

authors： Huang L,Critchley LA

更新日期：2013-12-01 00:00:00

abstract：:In theory, setting an infrared multi-gas analyser to measure a volatile anaesthetic different from that in the sampled gas mixture may cause interference with carbon dioxide and nitrous oxide readings. The theory was investigated during evaluation of the Dräger Cicero EM anaesthetic workstation for the Medical Devices...

journal_title：British journal of anaesthesia

authors： Wilkes AR,Mapleson WW

更新日期：1996-05-01 00:00:00

abstract：:A combination of exogenous surfactant and partial liquid ventilation (PLV) with perfluorocarbons should enhance gas exchange, improve respiratory mechanics and reduce tissue damage of the lung in acute lung injury (ALI). We used a small dose of exogenous surfactant with and without PLV in an experimental model of ALI ...

journal_title：British journal of anaesthesia

authors： Wolf S,Lohbrunner H,Busch T,Sterner-Kock A,Deja M,Sarrafzadeh A,Neumann U,Kaisers U

更新日期：2001-10-01 00:00:00

abstract：:This was a prospective, non-randomized, multicentre study of rocuronium (Org 9426) in 40 elective Caesarean section patients at full term without fetal distress. Anaesthesia was induced with thiopentone 4-6 mg kg-1 i.v. and rocuronium 0.6 mg kg-1 and maintained with isoflurane and nitrous oxide in oxygen. Monitors inc...

journal_title：British journal of anaesthesia

authors： Abouleish E,Abboud T,Lechevalier T,Zhu J,Chalian A,Alford K

更新日期：1994-09-01 00:00:00

abstract：:We have studied the efficacy of preoxygenation using the Triservice Anaesthetic Apparatus (TSA) in healthy patients and found it to be unsatisfactory. An alternative technique suitable for field use was explored. The Mapleson D system (Bain) was found to be suitable for preoxygenation with a fresh gas flow of only 4 l...

journal_title：British journal of anaesthesia

authors： Lowe DM,McFadzean W

更新日期：1991-02-01 00:00:00

abstract：:We describe the management of three patients undergoing awake carotid surgery who developed signs of cerebral ischaemia after carotid cross-clamping. Drug treatment to increase arterial blood pressure above baseline reversed the neurological deficit and an internal carotid artery shunt was not needed. Shunt insertion ...

journal_title：British journal of anaesthesia

authors： Stoneham MD,Warner O

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Circadian variation may affect many biological and pharmacological phenomena. METHODS:To assess circadian variations in labour pain perception, 222 consecutive nulliparous women with uncomplicated pregnancy, spontaneous labour, cervical dilatation (3-5 cm), ruptured membranes and normal fetal heart rate tra...

journal_title：British journal of anaesthesia

authors： Aya AG,Vialles N,Mangin R,Robert C,Ferrer JM,Ripart J,de La Coussaye JE

更新日期：2004-09-01 00:00:00

abstract：:Eighteen patients were studied, during operations under subarachnoid or extradural anaesthesia combined with general anaesthesia, to assess the influence of occlusion of inspiration on the duration of inspiration, and the likelihood of a relationship between lung volume and duration of inspiration. Ten patients breath...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:The second gas effect (SGE) is considered to be significant only during periods of large volume N(2)O uptake (VN(2)O); however, the SGE of small VN(2)O has not been studied. We hypothesized that the SGE of N(2)O on sevoflurane would become less pronounced when sevoflurane administration is started 60 min aft...

journal_title：British journal of anaesthesia

authors： Hendrickx JF,Carette R,Lemmens HJ,De Wolf AM

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The objective of the present study was to investigate sublingual microvascular blood flow and microcirculatory haemoglobin oxygen saturation (Smc(O(2))) during cardiopulmonary bypass (CPB) using constant systemic blood flow but different perfusion pressures achieved by phenylephrine administration. METHODS:...

journal_title：British journal of anaesthesia

authors： Maier S,Hasibeder WR,Hengl C,Pajk W,Schwarz B,Margreiter J,Ulmer H,Engl J,Knotzer H

更新日期：2009-04-01 00:00:00

abstract：:Seven patients are described in whom a prophylactic blood patch was instituted within 15 min of accidental dural puncture. Five of the patients received extradural anaesthesia before the blood patch, and one after the blood patch had been performed. In three of these patients further "top-up" doses of local anaestheti...

journal_title：British journal of anaesthesia

authors： Quaynor H,Corbey M

更新日期：1985-05-01 00:00:00