Abstract：
BACKGROUND:The ultrasound cardiac output monitor (USCOM) is a continuous wave Doppler system designed to measure cardiac output (CO) non-invasively and intermittently either from the pulmonary or from the aortic valve. USCOM scan quality is critical to obtaining reliable data and during anaesthesia it is said to deteriorate with increasing age. The aim of this study was to investigate the effect of age on supra-sternal USCOM scan repeatability during anaesthesia. METHODS:We performed a series of 6 USCOM scans in 180 patients of all ages after induction for routine surgery. A 12-point Cattermole (CS) score and 10-point insonation (IS) score were used to evaluate scan quality and ease of insonation. The coefficients of variation (CVs) of USCOM variables [CO, peak velocity, stroke volume index (SVI) and the corrected flow time] were derived from the series of six readings. RESULTS:In >95% of young patients (age <50 yr), it was easy to obtain a good-quality USCOM scan (CS>8). In these patients, repeatability of serial readings was good with CVs<5% and precision of less than ±10%. In older patients (>50 yr), scan quality and ease of insonation declined, with >25% of patients >60 yr having unreliable USCOM scans (CS<5). In these patients, the CV was >5-10%. In several elderly patients (>65 yr), we failed to locate the USCOM signal. Average scan time increased with age (30 to >60 s). SVI was also strongly correlated with scan quality (R(2)=0.77). CONCLUSIONS:Increasing age has a significant effect on USCOM scan quality and data reliability.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Huang L,Critchley LAdoi
10.1093/bja/aet254subject
Has Abstractpub_date
2013-12-01 00:00:00pages
907-15issue
6eissn
0007-0912issn
1471-6771pii
S0007-0912(17)30948-0journal_volume
111pub_type
杂志文章abstract：:We report two patients who developed skin necrosis following an intramuscular injection of non-steroidal anti-inflammatory drug into the anteriolateral area of their thigh. Both patients required further multiple operations and one developed life threatening septicaemia. They were left with disfiguring scars. Skin nec...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/88.1.139
更新日期：2002-01-01 00:00:00
abstract：:In the prone knee-chest position the spread of plain 0.5% bupivacaine in the cerebrospinal fluid and associated haemodynamic changes may be different compared with the horizontal position. A randomized comparison was performed in 40 ASA I-II patients, aged 24-61 yr, undergoing lumbar disc surgery. Subarachnoid injecti...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/79.5.609
更新日期：1997-11-01 00:00:00
abstract：:A recently installed anti-pollution system, initially designed to function in a passive mode, was evaluated, but found to be inconstant in its performance. A simple method of making the system active is described and evaluated. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/49.5.439
更新日期：1977-05-01 00:00:00
abstract：:Six patients with airway stenosis were submitted to bronchoscopy under general anaesthesia. Each was ventilated with a gas mixture of 50% oxygen and nitrogen using successively manual jet insufflation (JV) using the Sanders technique at 20 b.p.m., and high frequency jet ventilation (HFJV) at rates of 150, 300 and 500 ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/55.10.969
更新日期：1983-10-01 00:00:00
abstract：:Temazepam elixir 30 mg by mouth was compared with i.v. Diazemuls titrated to a maximum dose of 20 mg in a double-blind study of 50 patients undergoing elective minor oral surgery. The treatments produced a similar reduction in anxiety score and similar degrees of patient relaxation and co-operation. The diazepam group...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/60.1.18
更新日期：1988-01-01 00:00:00
abstract：:We carried out a randomized prospective study in 60 patients who had undergone major abdominal surgery for cancer. For postoperative pain control, 30 patients received continuous extradural infusion of 0.125% bupivacaine 12.5 mg h-1 and morphine 0.25 mg h-1 (EXI group) and 30 received patient-controlled analgesia (PCA...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/80.6.742
更新日期：1998-06-01 00:00:00
abstract：BACKGROUND:In 2016, the World Health Organization (WHO) strongly recommended the use of a high fraction of inspired oxygen (FiO2) in adult patients undergoing general anaesthesia to reduce the risk of surgical site infection (SSI). Since then, further trials have been published, trials included previously have come und...
journal_title：British journal of anaesthesia
pub_type： meta分析
doi：10.1016/j.bja.2018.11.024
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:In a prospective, randomized, double-blind, placebo-controlled trial, we investigated the effect of adding meperidine 10 mg to intrathecal bupivacaine on the duration of early postoperative analgesia in 40 patients having elective Caesarean section under spinal anaesthesia. METHODS:Patients received intrath...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/88.3.379
更新日期：2002-03-01 00:00:00
abstract：:We have compared bupivacaine 5 mg ml-1, either isobaric in saline 0.9% or hyperbaric in 8% glucose, for spinal anaesthesia in 100 children, aged 2-115 months, in a double-blind, randomized, parallel group, prospective study. Children were premedicated with diazepam 0.5 mg kg-1 orally. Seventy-two children were sedated...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/81.4.502
更新日期：1998-10-01 00:00:00
abstract：:The effect of gas leakage around an uncuffed tracheal tube on the performance of Heat and Moisture Exchangers (HME) was examined experimentally. Such leaks were shown to cause measurable decreases in the humidity output and efficiency of HME. The magnitude of the decrease in humidity output was shown to be dependent u...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/59.9.1181
更新日期：1987-09-01 00:00:00
abstract：BACKGROUND:Experimental studies and investigations in patients with cardiac diseases suggest that opioids at clinical concentrations have no important direct effect on myocardial relaxation and contractility. In vivo data on the effect of remifentanil on myocardial function in humans are scarce. This study aimed to inv...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeq414
更新日期：2011-04-01 00:00:00
abstract：:Several risk scores have been developed to calculate the probability of postoperative nausea and vomiting (PONV). However, the power to discriminate which individual will suffer from PONV is still limited. Thus, we wondered how the number of predictors in a score affects the discriminating power and how the characteri...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/86.6.822
更新日期：2001-06-01 00:00:00
abstract：:Plasma concentrations of pancuronium were measured in nine patients undergoing surgery because of total biliary obstruction. When compared with the averaged model-independent pharmacokinetic parameters obtained for normal patients, the terminal half-life of 270 min was more than twice normal (132 min, P less than 0.00...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/49.11.1103
更新日期：1977-11-01 00:00:00
abstract：:Maternal haemorrhage is the leading cause of preventable maternal death worldwide and encompasses antepartum, intrapartum, and postpartum bleeding. This review highlights factors that predispose to severe bleeding, its management, and the most recent treatment and guidelines. Advances in obstetric care have provided p...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aep303
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:The low and moderate doses of dexmedetomidine reduce arterial pressure and heart rate (HR), suggesting attenuation of sympathetic activity and dominance of cardiac-vagal activity. These autonomic responses under dexmedetomidine sedation may attenuate cardiovascular reflex responses to temporal reduction in a...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aep210
更新日期：2009-10-01 00:00:00
abstract：:The effect on intervillous blood flow of lumbar extradural analgesia for Caesarean section was studied in nine healthy women using xenon-133. Extradural anaesthesia was performed with lignocaine 1 1/2% 16--20 ml with adrenaline 5 microgram ml-1. Impairment of placental blood flow during the block was observed in seven...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/50.3.275
更新日期：1978-03-01 00:00:00
abstract：:We have tested the hypothesis that intradermal testing is a more effective method for determining the drug responsible for anaesthetic anaphylactic reactions than prick testing in 212 consecutive patients, aged more than 10 yr, referred to an anaesthetic allergy clinic over a 4-yr period. The study was a prospective, ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/79.1.59
更新日期：1997-07-01 00:00:00
abstract：:We report the anaesthetic management of a male neonate with congenital cyst adenoid malformation (CCAM) of the lung who underwent thoracotomy for resection of CCAM 24 h after birth and again at 24 days. The initial operation involved a 10-day admission to a paediatric intensive care unit (PICU) requiring ventilation, ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aei171
更新日期：2005-08-01 00:00:00
abstract：:We have compared the effects of progressive (30% and 60%) in vitro haemodilution with hydroxyethyl starch (HES), gelatin (GEL) and albumin (ALB) with haemodilution using 0.9% saline in 96 patients by thrombelastography. Haemodilution with HES, GEL and ALB significantly (P < 0.05) compromised coagulation time (k), angl...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/78.6.684
更新日期：1997-06-01 00:00:00
abstract：:The role of endothelin-1, a potent vasoconstrictor released by vascular endothelium, in the vasoconstriction that develops after prolonged operations is not clear. This study was performed in order to determine if there was any relationship between endothelin-1 and the degree of vasoconstriction during prolonged plast...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/74.6.661
更新日期：1995-06-01 00:00:00
abstract：BACKGROUND:The pharmacokinetic profile of local anaesthetics is influenced by the mode of administration. We sought to compare the pharmacokinetics of two doses of ropivacaine after fascia iliaca compartment (FIC) block in children. METHODS:In this prospective, double-blind study, children received an FIC block as a p...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aeh066
更新日期：2004-03-01 00:00:00
abstract：:The plasma decay of atracurium besylate was examined in two groups of six patients. Group I received atracurium 0.6 mg kg-1 and group II 0.3 mg kg-1 as a single bolus dose i.v. The plasma concentrations were measured by high performance liquid chromatography. An individual two-compartment pharmacokinetic model was use...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/55.2.113
更新日期：1983-02-01 00:00:00
abstract：:Cardiovascular risk prediction using clinical risk factors is integral to both the European and the American algorithms for preoperative cardiac risk assessment and perioperative management for non-cardiac surgery. We have reviewed these risk factors and their ability to guide clinical decision making. We examine thei...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aer194
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Double-lumen tubes (DLTs) are frequently used to establish one-lung ventilation (OLV). Their correct placement is crucial. We hypothesized that electrical impedance tomography (EIT) reliably displays distribution of ventilation between left and right lung and may thus be used to verify correct DLT placement ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aen166
更新日期：2008-09-01 00:00:00
abstract：:In a double-blind, placebo-controlled three-way cross over study, the efficacy of Ro 15-1788 200 mg, a new benzodiazepine antagonist, in blocking the amnesic, cognitive, psychomotor and subjective effects of diazepam 20 mg, was investigated in a group of six healthy male volunteers. The amnesic effects of diazepam wer...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/55.4.349
更新日期：1983-04-01 00:00:00
abstract：:Pre- and postjunctional effects of three ethers (enflurane, diethyle ether, and methoxyflurane) and three non-ethers (chloroform, halothane, and trichloroethylene) were studied in the rat phrenic nerve diaphragm preparation using standard microelectrode recording techniques. Depression of postjunctional function inclu...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/47.5.533
更新日期：1975-05-01 00:00:00
abstract：:We have investigated the effects of clonidine on gastric emptying of liquids in 30 patients. In a double-blind, randomized design, clonidine 150 micrograms, morphine 10 mg or saline in 1 ml was given i.m. One hour later, the patient drank a paracetamol solution (1.5 g in 50 ml water). Venous blood samples were obtaine...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/78.1.28
更新日期：1997-01-01 00:00:00
abstract：:Human plasma cholinesterase (E.C. 3.1.1.8) was shown to be inhibited by physiological concentrations of propanidid and suxamethonium using a colourimetric assay at 25 degrees C and pH 7.2 unit with butyrylthiocholine as substrate. Propanidid inhibited the enzyme in a non-competitive manner (I50 = 2.0 mmol litre-1; app...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/51.3.181
更新日期：1979-03-01 00:00:00
abstract：:A retrospective study of serious non-fatal complications of extradural block in obstetric practice was carried out using a postal questionnaire. Two hundred and three obstetric units in the United Kingdom (responsible for 2,580,000 deliveries from 1982 to 1986 inclusive) responded. A total of 505,000 extradural blocks...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/64.5.537
更新日期：1990-05-01 00:00:00
abstract：:Magnesium inhibits the release of acetylcholine from the motor nerve terminal and thus potentiates the action of the non-depolarizing neuromuscular blocking drugs. We have examined the possibility that this effect might enhance the speed of onset of non-depolarizing block with pancuronium. Following the administration...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/66.2.247
更新日期：1991-02-01 00:00:00
