Utility of clinical risk predictors for preoperative cardiovascular risk prediction.

abstract：BACKGROUND:High-dose glucocorticoid may reduce postsurgical pain and improve recovery. We hypothesized that 125 mg methylprednisolone (MP) would reduce time to meet functional discharge criteria after total hip arthroplasty (THA). METHODS:Forty-eight patients undergoing unilateral THA under spinal anaesthesia were con...

journal_title：British journal of anaesthesia

authors： Lunn TH,Andersen LØ,Kristensen BB,Husted H,Gaarn-Larsen L,Bandholm T,Ladelund S,Kehlet H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A significantly increased risk of acute kidney injury (AKI) with the prophylactic use of aprotinin has been reported in adults undergoing cardiac surgery, but not in children. Blood product transfusions have also been shown to carry an independent risk of AKI. The present study assessed associations between ...

journal_title：British journal of anaesthesia

authors： Bojan M,Vicca S,Boulat C,Gioanni S,Pouard P

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Data on bupivacaine concentrations in the cerebral spinal fluid (CSF) during spinal anaesthesia are scarce. The purpose of this study was to determine the concentration of bupivacaine in the lumbar CSF of patients with an adequate level of spinal anaesthesia after injection of plain bupivacaine 0.5%. METHOD...

journal_title：British journal of anaesthesia

authors： Ruppen W,Steiner LA,Drewe J,Hauenstein L,Brugger S,Seeberger MD

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Psychological factors are thought to drive inter-patient variations in anaesthetic and analgesic requirements. This cross-sectional study investigated whether preoperative psychological factors can predict anaesthetic requirements and postoperative pain. METHODS:Before total thyroidectomy, 100 consecutive w...

journal_title：British journal of anaesthesia

authors： Kil HK,Kim WO,Chung WY,Kim GH,Seo H,Hong JY

更新日期：2012-01-01 00:00:00

abstract：:We have studied the tone of the lower oesophageal sphincter (LOS) in 40 adults undergoing routine body surface surgery and allocated randomly to receive anaesthesia either by face mask and Guedel airway or by laryngeal mask airway. In the laryngeal mask group there was a mean (SEM) decrease in barrier pressure (LOS mi...

journal_title：British journal of anaesthesia

authors： Rabey PG,Murphy PJ,Langton JA,Barker P,Rowbotham DJ

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Pressures (Pe) exerted by bronchial blockers on the inner wall of the bronchi may cause mucosal ischaemia. Our aims were as follows: (i) to compare the intracuff pressure (Pi) and Pe exerted by commercially available bronchial blockers in an in vitro and an ex vivo model; (ii) to investigate the influence of...

journal_title：British journal of anaesthesia

authors： Carassiti M,Mattei A,Pizzo CM,Vallone N,Saccomandi P,Schena E

更新日期：2016-09-01 00:00:00

abstract：:In a double-blind, placebo-controlled three-way cross over study, the efficacy of Ro 15-1788 200 mg, a new benzodiazepine antagonist, in blocking the amnesic, cognitive, psychomotor and subjective effects of diazepam 20 mg, was investigated in a group of six healthy male volunteers. The amnesic effects of diazepam wer...

journal_title：British journal of anaesthesia

authors： O'Boyle C,Lambe R,Darragh A,Taffe W,Brick I,Kenny M

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which reflect spinal excitability, has been shown for propofol. We have assessed the concentration-dependent F-wave suppression by propofol and related it to th...

journal_title：British journal of anaesthesia

authors： Baars JH,Tas S,Herold KF,Hadzidiakos DA,Rehberg B

更新日期：2006-01-01 00:00:00

abstract：:We describe the performance of the pneuPAC hyperbaric variant HB, a ventilator designed for use in a one-man hyperbaric chamber. The ventilator delivered minute volumes of 11-23 litre at 1 atm abs to 7.6-16 litre at 2.5 atm abs. The delivered minute volume may be controlled easily from outside the chamber by manipulat...

journal_title：British journal of anaesthesia

authors： Spittal MJ,Hunter SJ,Jones L

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:The influence of common disturbances seen in preeclampsia, such as changes in strong ions and weak acids (particularly albumin) on acid-base status, has not been fully elucidated. The aims of this study were to provide a comprehensive acid-base analysis in severe preeclampsia and to identify potential new bi...

journal_title：British journal of anaesthesia

authors： Ortner CM,Combrinck B,Allie S,Story D,Landau R,Cain K,Dyer RA

更新日期：2015-08-01 00:00:00

abstract：:Plasma concentrations of amethocaine were measured after topical application of amethocaine cream 2 g (5% w/w) to the dorsum of the right hand of 10 adult volunteers. The cream was applied for 240 min and plasma was assayed for amethocaine and its metabolite p-n-butylaminobenzoic acid at 0, 30, 60, 90, 120 and 240 min...

journal_title：British journal of anaesthesia

authors： Mazumdar B,Tomlinson AA,Faulder GC

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Sepsis-induced organ failure is the major cause of death in critical care units, and is characterized by a massive dysregulated inflammatory response and oxidative stress. We investigated the effects of treatment with antioxidants that protect mitochondria (MitoQ, MitoE, or melatonin) in a rat model of lipop...

journal_title：British journal of anaesthesia

authors： Lowes DA,Webster NR,Murphy MP,Galley HF

更新日期：2013-03-01 00:00:00

abstract：:This report describes the anaesthetic management of a ventricular arrhythmia-prone patient with a prolonged Q-T interval for closed reduction and wiring of a mandibular fracture. The patient was premedicated with propranolol and anaesthetized with isoflurane (inhalation). Documentation of heart rate v. Q-T interval re...

journal_title：British journal of anaesthesia

authors： Medak R,Benumof JL

更新日期：1983-04-01 00:00:00

abstract：:A patient with a foreign body penetrating the neck and chest was found to have physical signs which were consistent with serious tracheal injury and included a large movement of air through the lower part of the neck. The subsequent management of the patient and the difficult problem of securing an airway are describe...

journal_title：British journal of anaesthesia

authors： Brierley JK,Oates J,Bogod DG

更新日期：1991-06-01 00:00:00

abstract：:We have undertaken a prospective, randomized study to determine the incidence of postoperative nausea and vomiting during intensive care stay after cardiac surgery, and to study the effect of addition of droperidol to an infusion of morphine used for postoperative analgesia. Data from 398 patients were examined. The u...

journal_title：British journal of anaesthesia

authors： Grebenik CR,Allman C

更新日期：1996-09-01 00:00:00

abstract：:We present an unusual case of hypercapnia and surgical emphysema during transanal endoscopic microsurgery, which led to delayed post-operative ventilatory failure. The hypercapnia and surgical emphysema were secondary to rectal insufflation with carbon dioxide used to facilitate visualization and resection of a rectal...

journal_title：British journal of anaesthesia

authors： Kerr K,Mills GH

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) pressure-volume (PV) loops were used to compare the functional effects that accompany the cardioprotection seen with desflurane, sevoflurane, and propofol in a rabbit preparation of coronary ischaemia-reperfusion (IR). METHODS:Male New Zealand White rabbits (n=48) were anaesthetized wi...

journal_title：British journal of anaesthesia

authors： Andrews DT,Royse AG,Royse CF

更新日期：2009-11-01 00:00:00

abstract：:Transoesophageal echocardiography (TOE) is valuable for perioperative monitoring in patients at risk from haemodynamic disturbance. However, its use is not practicable in patients undergoing surgical procedures under regional anaesthesia. We describe two cases showing that transthoracic echocardiography (TTE) has the ...

journal_title：British journal of anaesthesia

authors： Filipovic M,Seeberger MD,Schneider MC,Schmid M,Pargger H,Hunziker P,Skarvan K

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:A recent study showed that the noble gas helium induces early myocardial preconditioning. Cyclooxygenase-2 (COX-2) has been shown to be an important mediator in the signal transduction of late preconditioning. In the present study, we investigated whether helium induces late preconditioning in a concentratio...

journal_title：British journal of anaesthesia

authors： Huhn R,Heinen A,Weber NC,Hieber S,Hollmann MW,Schlack W,Preckel B

更新日期：2009-05-01 00:00:00

abstract：:The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome. The results, which are expressed in accordance with the criteria of the European MH Group, defined five of the subjects as MHN and one patient as MHE. It is concluded tha...

journal_title：British journal of anaesthesia

authors： Krivosic-Horber R,Adnet P,Guevart E,Theunynck D,Lestavel P

更新日期：1987-12-01 00:00:00

abstract：:The effect of pretreatment with suxamethonium, gallamine or pancuronium on suxamethonium-induced fasciculations and myalgia was studied in a controlled, randomized and double-blind clinical trial. Both fasciculations and myalgia were assessed on a four-point rating scale. There was no significant correlation between f...

journal_title：British journal of anaesthesia

authors： O'Sullivan EP,Williams NE,Calvey TN

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Perioperative studies of patients following hip fracture have large heterogeneity within their reported outcomes. This study aimed to develop a core outcome set for use in perioperative studies comparing the types of anaesthesia for hip fracture surgery. METHODS:The consensus process consisted of a systemat...

journal_title：British journal of anaesthesia

authors： O'Donnell CM,Black N,McCourt KC,McBrien ME,Clarke M,Patterson CC,Blackwood B,McAuley DF,Shields MO

更新日期：2019-01-01 00:00:00

abstract：:We studied the pharmacokinetics of glycopyrronium in 11 uraemic patients undergoing cadaveric renal transplantation and in seven ASA I control patients undergoing general surgery. Glycopyrronium 4 micrograms kg-1 was given i.v. before induction of anaesthesia. Blood and urine samples were collected for up to 24 h for ...

journal_title：British journal of anaesthesia

authors： Kirvelä M,Ali-Melkkilä T,Kaila T,Iisalo E,Lindgren L

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Tapentadol is an analgesic agent for treatment of acute and chronic pain that activates the µ-opioid receptor combined with inhibition of neuronal norepinephrine reuptake. Both mechanisms are implicated in activation of descending inhibitory pain pathways. In this study, we investigated the influence of tape...

journal_title：British journal of anaesthesia

authors： Niesters M,Proto PL,Aarts L,Sarton EY,Drewes AM,Dahan A

更新日期：2014-07-01 00:00:00

abstract：:Cytokine synthesis and release is an essential component of the innate immune system, but inappropriate, excessive production results in a generalized systemic inflammatory response which damages distant organs. Recent research has identified an immunomodulatory function of the vagus nerve whereby activation of the ef...

journal_title：British journal of anaesthesia

authors： Johnston GR,Webster NR

更新日期：2009-04-01 00:00:00

abstract：:The rapid detection and evaluation of patients presenting with perioperative neurological dysfunction is of great clinical relevance. Biomarkers have been defined as biological molecules that can be used as an indicator of new onset or progression of a biological process or effect of treatment. Biomarkers have become ...

journal_title：British journal of anaesthesia

authors： Cata JP,Abdelmalak B,Farag E

更新日期：2011-12-01 00:00:00

abstract：:We studied the size 4 laryngeal mask airway (LMA) to test the hypothesis that oropharyngeal leak pressure and fibreoptic position improves with increasing cuff volume. After LMA insertion, 50 anaesthetized adult patients had the cuff inflated in 5-ml increments to 40 ml. Oropharyngeal leak pressure was optimal at 15 m...

journal_title：British journal of anaesthesia

authors： Keller C,Pühringer F,Brimacombe JR

更新日期：1998-08-01 00:00:00

abstract：:Three anaesthetic techniques based on isoflurane were compared in outpatients undergoing laparoscopy. Sixty healthy patients were randomly allocated to receive isoflurane via mask (spontaneous respiration), via tracheal tube (spontaneous respiration) or via tracheal tube with controlled ventilation. Moderate hypercarb...

journal_title：British journal of anaesthesia

authors： Kenefick JP,Leader A,Maltby JR,Taylor PJ

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The purpose of this prospective study was to assess the blood-sparing effect, the quality of analgesia, and the incidence of side-effects of a low-dose regime of intrathecal opioids (ITO) when compared with those of a high-dose regime in scoliosis surgery in children. METHODS:Forty-six children were randoml...

journal_title：British journal of anaesthesia

authors： Eschertzhuber S,Hohlrieder M,Keller C,Oswald E,Kuehbacher G,Innerhofer P

更新日期：2008-04-01 00:00:00

abstract：:We have investigated the relationship between the extent of spinal block and occurrence of sedation. In a first series of 43 patients, the distribution of sedation score (measured on the Ramsey scale) was related to the extent of spinal block (pinprick). In a second series of 33 patients, the relationship between seda...

journal_title：British journal of anaesthesia

authors： Gentili M,Huu PC,Enel D,Hollande J,Bonnet F

更新日期：1998-12-01 00:00:00