Priming of pancuronium with magnesium.

abstract：BACKGROUND:The objective of the present study was to investigate sublingual microvascular blood flow and microcirculatory haemoglobin oxygen saturation (Smc(O(2))) during cardiopulmonary bypass (CPB) using constant systemic blood flow but different perfusion pressures achieved by phenylephrine administration. METHODS:...

journal_title：British journal of anaesthesia

authors： Maier S,Hasibeder WR,Hengl C,Pajk W,Schwarz B,Margreiter J,Ulmer H,Engl J,Knotzer H

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Low-dose droperidol is suggested to be cost-effective in preventing nausea and vomiting after ambulatory surgery. This clinical study evaluated patient postural stability using a computerized force platform after an i.v. dose of droperidol 0.625 mg in outpatients undergoing gynaecological dilatation and cure...

journal_title：British journal of anaesthesia

authors： Song D,Chung F,Yogendran S,Wong J

更新日期：2002-06-01 00:00:00

abstract：:A 39-year-old male suffered a closed chest deceleration injury. He presented with clinical and radiological signs consistent with trauma to the thoracic aorta, but also developed sinus bradycardia which was relieved by drainage of a haemothorax. The possible mechanisms of the changes in heart rate are discussed and di...

journal_title：British journal of anaesthesia

authors： Kong RS,Wood PR

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:We studied the potential neuroprotective effects of halothane and desflurane, compared with the awake state, on infarct size following 2 h of intraluminal middle cerebral artery occlusion (MCAo) and 22 h of reperfusion. METHODS:Male Sprague-Dawley rats were anaesthetized with desflurane or halothane, intuba...

journal_title：British journal of anaesthesia

authors： Haelewyn B,Yvon A,Hanouz JL,MacKenzie ET,Ducouret P,Gérard JL,Roussel S

更新日期：2003-09-01 00:00:00

abstract：:The induction dose requirements of propofol were compared in three age groups in 300 unpremedicated healthy Chinese children: group A, younger than 2 yr (n = 48); group B, 2-5 yr (n = 117); group C, 6-12 yr (n = 135). Patients in each group were allocated randomly to receive one of eight doses of propofol (1.2, 1.4, 1...

journal_title：British journal of anaesthesia

authors： Aun CS,Short SM,Leung DH,Oh TE

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Arousal after sevoflurane anaesthesia has been detectable by monitoring changes in skin conductance (SC) with similar accuracy as monitoring Bispectral Index (BIS). As SC monitoring detects changes in sympathetic tone, the measurements might be confounded by the sympatholytic properties of propofol, a compon...

journal_title：British journal of anaesthesia

authors： Ledowski T,Bromilow J,Paech MJ,Storm H,Hacking R,Schug SA

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:With the increasing prevalence of children who are overweight and with obesity, anaesthesiologists must determine the optimal dosing of medications given the altered pharmacokinetics and pharmacodynamics in this population. We therefore determined the single dose of dexmedetomidine that provided sufficient s...

journal_title：British journal of anaesthesia

authors： Wu B,Shan J,Zhou Q,Wang L

更新日期：2021-01-22 00:00:00

abstract：:Alveolar type II (ATII) cells perform many important functions within the lung, including surfactant metabolism. We have investigated the effects of isoflurane and different i.v. anaesthetics on cell metabolism in primary cultures of rat ATII cells. Biosynthesis of phosphatidylcholine, the main phospholipid component ...

journal_title：British journal of anaesthesia

authors： Molliex S,Crestani B,Dureuil B,Rolland C,Aubier M,Desmonts JM

更新日期：1999-05-01 00:00:00

abstract：:We have used mivacurium in four myasthenic patients presenting for thymectomy. Supramaximal single twitch stimulation was applied to the ulnar nerve at the wrist and the force of contraction of the adductor pollicis was measured. After an initial bolus dose of 30 micrograms kg-1 (approximately one-fifth of the normal ...

journal_title：British journal of anaesthesia

authors： Paterson IG,Hood JR,Russell SH,Weston MD,Hirsch NP

更新日期：1994-10-01 00:00:00

abstract：INTRODUCTION:Compared with term neonates, preterm babies are more likely to die from sepsis. However, the combined effects of sepsis and prematurity on neonatal postoperative mortality are largely unknown. Our objective was to quantify the proportion of neonatal postoperative mortality that is attributable to the syner...

journal_title：British journal of anaesthesia

authors： Mpody C,Shepherd EG,Thakkar RK,Dairo OO,Tobias JD,Nafiu OO

更新日期：2020-12-01 00:00:00

abstract：:Cholinesterase phenotyping studies have been carried out in two laboratories on blood specimens from 28 patients shown to be susceptible to malignant hyperpyrexia. In contrast to previously published reports, no evidence could be found for an increase in the frequency of the E1u E1f genotype above that known to occur ...

journal_title：British journal of anaesthesia

authors： Evans RT,Iqbal J,Ellis FR,Halsall PJ,Dietz AA,Lubrano T,Rubinstein HM

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the ci...

journal_title：British journal of anaesthesia

authors： Gögenur I,Wildschiøtz G,Rosenberg J

更新日期：2008-01-01 00:00:00

abstract：:We have evaluated the clinical utility and blood propofol concentrations produced with two different infusion regimens for propofol, given to supplement 67% nitrous oxide-morphine anaesthesia. Patients received a standardized three-step infusion of propofol based either on body weight (weight-corrected group) or on a ...

journal_title：British journal of anaesthesia

authors： Sear JW,Glen JB

更新日期：1995-04-01 00:00:00

abstract：:In a prospective randomized multi-centre study, the mortality following internal fixation surgery for fracture of the upper femur was investigated in 538 elderly patients allocated to receive subarachnoid blockade or general (narcotic-relaxant) anaesthesia. The 28-day mortality was 6.6% with subarachnoid, and 5.9% wit...

journal_title：British journal of anaesthesia

authors： Davis FM,Woolner DF,Frampton C,Wilkinson A,Grant A,Harrison RT,Roberts MT,Thadaka R

更新日期：1987-09-01 00:00:00

abstract：:Intragastric pressure was measured in 20 patients before, and immediately after, the induction of anaesthesia with thiopentone. Intragastric pressure decreased in patients whose weights were the same as or less than expected, and increased in five of seven patients whose weights were greater than expected (P = 0.0013)...

journal_title：British journal of anaesthesia

authors： Drummond GB,Park GR

更新日期：1984-08-01 00:00:00

abstract：:We describe a 25 mg intrathecal morphine overdose during a combined spinal-epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided. ...

journal_title：British journal of anaesthesia

authors： Cannesson M,Nargues N,Bryssine B,Debon R,Boselli E,Chassard D

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Early clot amplitudes measured on thromboelastometry (ROTEM®) predict maximum clot firmness (MCF) in adults. In this multicentre, retrospective study, we aimed to confirm the suspected relationship between early ROTEM® variables and MCF, in children undergoing cardiac or non-cardiac surgery. METHODS:4762 RO...

journal_title：British journal of anaesthesia

authors： Perez-Ferrer A,Vicente-Sanchez J,Carceles-Baron MD,Van der Linden P,Faraoni D

更新日期：2015-12-01 00:00:00

abstract：:One hundred patients presenting for surgical treatment of fractured neck of femur were allocated to receive either spinal (SAB) or general (GA) anaesthesia. Before operation, the mean PaO2 was 9.04 kPa. There was a significant decrease in PaO2 of 0.68 kPa in GA group at 1 h after operation, while blood-gas values were...

journal_title：British journal of anaesthesia

authors： McKenzie PJ,Wishart HY,Dewar KM,Gray I,Smith G

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:The diagnosis of abdominal compartment syndrome depends upon the demonstration of an elevated intra-abdominal pressure (IAP). Direct measures of IAP are impractical in the critical care unit; intravesical pressure (IVP) and intragastric pressure (IGP) should represent acceptable surrogate measures. IVP is th...

journal_title：British journal of anaesthesia

authors： Turnbull D,Webber S,Hamnegard CH,Mills GH

更新日期：2007-05-01 00:00:00

abstract：:The serum concentrations of fazadinium and its metabolites were measured in 14 surgical patients with end-stage renal failure and in 11 patients free from kidney disease undergoing abdominal surgery. A two-compartment open model was used in the pharmacokinetic analysis of the data. The elimination half-life (T 1/2 bet...

journal_title：British journal of anaesthesia

authors： Duvaldestin P,Bertrand JC,Concina D,Henzel D,Lareng L,Desmonts JM

更新日期：1979-10-01 00:00:00

abstract：:One hundred and one patients with osteoarthritis were randomly allocated to undergo total hip arthroplasty under either spinal (subarachnoid) or general anaesthesia. Venous blood was sampled before, during and after surgery and on the 5th day after operation to study the haemostatic mechanism. There were no preoperati...

journal_title：British journal of anaesthesia

authors： Davis FM,McDermott E,Hickton C,Wells E,Heaton DC,Laurenson VG,Gillespie WJ,Foate J

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:The minimum effective volume of local anaesthetic needed to provide effective analgesia of the four main branches of the axillary brachial plexus is unknown. This study was performed to determine the minimum volume of local anaesthetic required to surround the nerves of the axillary brachial plexus and docum...

journal_title：British journal of anaesthesia

authors： Harper GK,Stafford MA,Hill DA

更新日期：2010-05-01 00:00:00

abstract：:Arterial oxygenation was measured in patients being ventilated artificially for respiratory failure, initially at the FIO2 that had been selected clinically to achieve PaO2 at least normal, and then at each of two or three progressively increased FIO2 values up to about 0.9. Impairment of oxygen transfer was assessed ...

journal_title：British journal of anaesthesia

authors： Drummond GB,Zhong NS

更新日期：1983-01-01 00:00:00

abstract：:We describe three histaminoid reactions occurring on induction of anaesthesia. The patients were all resuscitated successfully and subsequent skin testing suggested sensitivity to rocuronium. In this hospital, the incidence of such reactions is of the order of 1 in 3000. This may be coincidental but suggests that ther...

journal_title：British journal of anaesthesia

authors： Neal SM,Manthri PR,Gadiyar V,Wildsmith JA

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Propofol is used during living-related donor liver transplantation because its metabolism is not greatly affected by liver failure. However, the pharmacokinetics of propofol during liver transplantation have not been fully defined. The purpose of this study was to evaluate the apparent systemic clearance of ...

journal_title：British journal of anaesthesia

authors： Takizawa D,Sato E,Hiraoka H,Tomioka A,Yamamoto K,Horiuchi R,Goto F

更新日期：2005-11-01 00:00:00

abstract：:We have compared bispectral index (BIS), 95% spectral edge frequency (SEF) and approximate entropy (ApEn) in 37 patients during induction and recovery from a short general anaesthetic. Heart rate variability (HRV) was also compared during induction only. These indices were noted at the start of induction, when a syrin...

journal_title：British journal of anaesthesia

authors： Sleigh JW,Donovan J

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Anterograde, but not retrograde, amnesia has been demonstrated following midazolam administration. However, there have been no studies investigating whether or not immediate retrograde amnesia can be produced with midazolam. METHODS:After ethics committee approval and consent, 40 adult patients undergoing s...

journal_title：British journal of anaesthesia

authors： Bulach R,Myles PS,Russnak M

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Acute pulmonary embolism (APE) is an important clinical problem in patients after major surgery and often remains a difficult diagnosis because of unspecific clinical symptoms. Therefore, we investigated the role of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for the detection of APE. MET...

journal_title：British journal of anaesthesia

authors： Winkler BE,Schuetz W,Froeba G,Muth CM

更新日期：2012-12-01 00:00:00

abstract：:Alcuronium 0.16 mg kg-1 was used to provide neuromuscular blockade in patients with chronic renal failure undergoing renal transplantation. Relaxation was found to be adequate for intubation and surgery. There were minimal alterations to cardiovascular variables. The dose required was small, and complete reversal occu...

journal_title：British journal of anaesthesia

authors： Kaushik S,Grover VK,Singh H,Yadav RV

更新日期：1984-11-01 00:00:00

abstract：:Perioperative risk of death after general surgery is quoted as overall less than 1%. However, each individual's risk varies widely according to many identified factors with some having a significantly increased risk of a worse outcome. The observation that manipulating and targeting certain physiological parameters in...

journal_title：British journal of anaesthesia

authors： Tote SP,Grounds RM

更新日期：2006-07-01 00:00:00