Early thromboelastometry variables predict maximum clot firmness in children undergoing cardiac and non-cardiac surgery.

abstract：:The auditory steady state response (ASSR) is a sinusoidal evoked potential elicited by rapidly repeated auditory stimuli. The ASSR was recorded in eight patients during high-dose sufentanil anaesthesia for cardiac surgery in order to assess its usefulness as a measure of the level of consciousness. The electroencephal...

journal_title：British journal of anaesthesia

authors： Plourde G,Boylan JF

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Prolonged postoperative decrease in lung function is common after major upper abdominal surgery. Evidence suggests that ventilation with low tidal volumes may limit the damage during mechanical ventilation. We compared postoperative lung function of patients undergoing upper abdominal surgery, mechanically v...

journal_title：British journal of anaesthesia

authors： Treschan TA,Kaisers W,Schaefer MS,Bastin B,Schmalz U,Wania V,Eisenberger CF,Saleh A,Weiss M,Schmitz A,Kienbaum P,Sessler DI,Pannen B,Beiderlinden M

更新日期：2012-08-01 00:00:00

abstract：:All 484 candidates for the 1988 Fellowship in Anaesthesia (Part Three) were surveyed to investigate any differences between successful and unsuccessful candidates in study techniques, work and domestic factors, and examination history that might lead to better guidance to those preparing for the examination and an imp...

journal_title：British journal of anaesthesia

authors： David AC,Elton RA,Spence AA,Hatch DJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...

journal_title：British journal of anaesthesia

authors： Marty AP,Schmelzer S,Thomasin RA,Braun J,Zalunardo MP,Spahn DR,Breckwoldt J

更新日期：2020-07-01 00:00:00

abstract：:The isolated rat hepatocyte model has been used to assess the hepatotoxicity of a number of i.v. anaesthetic induction agents. Ketamine, Althesin and CCI 12923 (minaxolone) all inhibited gluconeogenesis and urea formation from alanine. There was also a decrease in the cell ATP concentration, and a dose-related increas...

journal_title：British journal of anaesthesia

authors： Sear JW,McGivan JD

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:General anaesthesia is a balance between hypnosis and analgesia. We investigated whether an increase in remifentanil blood concentration would reduce the amount of propofol required to maintain a comparable level of anaesthesia in 60 patients undergoing ambulatory surgery. METHODS:Patients were allocated ra...

journal_title：British journal of anaesthesia

authors： Milne SE,Kenny GN,Schraag S

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:In critically ill children, monitoring of cardiac output (CO) is essential to guide haemodynamic management and facilitate cardiovascular therapy. The ultrasound dilution technique (UDT), a novel minimally invasive indicator method, was recently introduced to determine CO. We validated UDT against the 'gold ...

journal_title：British journal of anaesthesia

authors： Boehne M,Baustert M,Paetzel V,Köditz H,Schoof S,Happel CM,Bertram H

更新日期：2014-03-01 00:00:00

abstract：:We report the safe use of remifentanil as part of the anaesthetic technique in a patient undergoing major head and neck surgery who was being treated for depressive illness with the non-specific monoamine oxidase inhibitor (MAOI) phenelzine. ...

journal_title：British journal of anaesthesia

authors： Ure DS,Gillies MA,James KS

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Atelectasis is known to develop during anaesthesia and after operation atelectasis leads to impaired oxygenation. Lung recruitment manoeuvres, positive end-expiratory pressure (PEEP), and continuous positive airway pressure (CPAP) have been proposed for reduction of atelectasis but their benefits have not be...

journal_title：British journal of anaesthesia

authors： Lumb AB,Greenhill SJ,Simpson MP,Stewart J

更新日期：2010-05-01 00:00:00

abstract：:A high degree of safety from fires and explosions exists in operating theatres in the U.K. and this is reflected in the extremely low number of fatal and non-fatal accidents which occur. This has been achieved by safety precautions which in some respects have been over-careful and overexpensive. Antistatic precautions...

journal_title：British journal of anaesthesia

authors： Vickers MD

更新日期：1978-07-01 00:00:00

abstract：:Thirty-two patients received lumbar extradural anaesthesia for elective Caesarean section. The results obtained from this series were compared with those from a similar (control) group of parturients who received general anaesthesia. The extradural group (mothers and infants) were metabolically acidaemic relative to c...

journal_title：British journal of anaesthesia

authors： Downing JW,Houlton PC,Barclay A

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Ketamine is widely used as an i.v. anaesthetic agent and as a drug of abuse. Hepatocytes contribute to the metabolism of endogenous and exogenous substances. This study evaluated the toxic effects of S-(+)-ketamine and possible mechanisms using human hepatoma HepG2 cells as the experimental model. METHODS:H...

journal_title：British journal of anaesthesia

authors： Lee ST,Wu TT,Yu PY,Chen RM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The minimum alveolar concentration (MAC) is a traditional index of the hypnotic potency of an inhalational anaesthetic. To investigate the anaesthetic as well as the unwanted effects of xenon (Xe) in a swine model, it is useful to know MAC(Xe). METHODS:The study was performed using ten swine (weight 27.8-35...

journal_title：British journal of anaesthesia

authors： Hecker KE,Horn N,Baumert JH,Reyle-Hahn SM,Heussen N,Rossaint R

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Single preoperative gabapentinoid (gabapentin and pregabalin) administration has been associated with respiratory depression during Phase I anaesthesia recovery. In this study, we assess for associations between chronic (home) use and perioperative administration (preoperative and postoperative) of gabapenti...

journal_title：British journal of anaesthesia

authors： Deljou A,Hedrick SJ,Portner ER,Schroeder DR,Hooten WM,Sprung J,Weingarten TN

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for...

journal_title：British journal of anaesthesia

authors： Zuppa AF,Nicolson SC,Wilder NS,Ibla JC,Gottlieb EA,Burns KM,Stylianou M,Trachtenberg F,Ni H,Skeen TH,Andropoulos DB,Pediatric Heart Network Investigators.

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Descriptions of the pharmacokinetics and metabolism of morphine and its metabolites in young children are scant. Previous studies have not differentiated the effects of size from those related to age during infancy. METHODS:Postoperative children 0-3 yr old were given an intravenous loading dose of morphine...

journal_title：British journal of anaesthesia

authors： Bouwmeester NJ,Anderson BJ,Tibboel D,Holford NH

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Vasopressor agents are used to prevent intraoperative hypotension and ensure adequate perfusion. Vasopressors are usually administered as intermittent boluses or manually adjusted infusions, but this practice requires considerable time and attention. We have developed a closed-loop vasopressor (CLV) controll...

journal_title：British journal of anaesthesia

authors： Joosten A,Alexander B,Duranteau J,Taccone FS,Creteur J,Vincent JL,Cannesson M,Rinehart J

更新日期：2019-10-01 00:00:00

abstract：:The insufflation of oxygen at 1 litre kg-1 min-1 via two endobronchial catheters (called continuous flow ventilation (CFV)) maintained a normal PaCO2 and a constant PaO2 in anaesthetized paralysed dogs and in five out of seven cats. In two cats with a high carbon dioxide production, CFV failed to maintain carbon dioxi...

journal_title：British journal of anaesthesia

authors： Perl A,Whitwam JG,Chakrabarti MK,Taylor VM

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the effects of phosphodiesterase type III and V (PDEIII and PDEV) inhibition on pulmonary and systemic haemodynamics in a porcine model of acute pulmonary hypertension. METHODS:Twenty-four adult swine were anaesthetized with 1 MAC isoflurane and mechanically ventilated with an FI(O(2)) of 100%. ...

journal_title：British journal of anaesthesia

authors： Lobato EB,Beaver T,Muehlschlegel J,Kirby DS,Klodell C,Sidi A

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Tetrodotoxin (TTX) is a powerful sodium channel blocker extracted from the puffer fish. The analgesic effects of TTX were investigated in different animal pain models. METHODS:Wistar rats were submitted to the formalin test and to partial ligation of the sciatic nerve (Seltzer's model). Swiss Webster mice w...

journal_title：British journal of anaesthesia

authors： Marcil J,Walczak JS,Guindon J,Ngoc AH,Lu S,Beaulieu P

更新日期：2006-06-01 00:00:00

abstract：Background:There is growing evidence that beta-blockade may reduce mortality in selected patients with sepsis. However, it is unclear if a pre-existing, chronic oral beta-blocker therapy should be continued or discontinued during the acute phase of severe sepsis and septic shock. Methods:The present secondary analysis...

journal_title：British journal of anaesthesia

authors： Fuchs C,Wauschkuhn S,Scheer C,Vollmer M,Meissner K,Kuhn SO,Hahnenkamp K,Morelli A,Gründling M,Rehberg S

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:There are no published data to predict tracheostomy tube size as growth proceeds in children requiring long-term ventilation. METHODS:A retrospective audit was undertaken of children having long-term ventilation, managed from the Southport spinal injuries unit. The dates of step-up in size of tracheostomy t...

journal_title：British journal of anaesthesia

authors： Behl S,Watt JW

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Transtracheal jet ventilation (TTJV) is recommended in several airway guidelines as a potentially life-saving procedure during the 'Can't Intubate Can't Oxygenate' (CICO) emergency. Some studies have questioned its effectiveness. METHODS:Our goal was to determine the complication rates of TTJV in the CICO e...

journal_title：British journal of anaesthesia

authors： Duggan LV,Ballantyne Scott B,Law JA,Morris IR,Murphy MF,Griesdale DE

更新日期：2016-09-01 00:00:00

abstract：:A randomized, double-blind study of 40 women was performed to compare patient controlled anaesthesia (PCA) morphine requirements after spinal anaesthesia for elective Caesarean section. The women received 0.2 mg of either morphine or diamorphine mixed with 0.5% bupivacaine in 8% dextrose. There were no significant dif...

journal_title：British journal of anaesthesia

authors： Husaini SW,Russell IF

更新日期：1998-08-01 00:00:00

abstract：:We evaluated the use of an inexpensive trans-illuminating light wand for tracheal intubation. Expertise in its use was acquired quickly, thereby providing successful per-oral intubation in all patients who were able to open the mouth, irrespective of the view obtained of the epiglottis and larynx. ...

journal_title：British journal of anaesthesia

authors： Ainsworth QP,Howells TH

更新日期：1989-05-01 00:00:00

abstract：:We have studied the pharmacokinetics of lignocaine in children after local infiltration for cleft palate surgery. After induction of anaesthesia, lignocaine 2.5 mg kg-1 with adrenaline 1:200,000 was injected into the palate. Blood samples were collected before and at 2, 5, 10, 15, 20, 30, 60 and 120 min after infiltra...

journal_title：British journal of anaesthesia

authors： Michael S,Barker I,Henderson P,Griffiths RW,Reilly CS

更新日期：1992-12-01 00:00:00

abstract：:Postoperative management following major surgery in patients with neuromuscular disorders associated with scoliosis is frequently complicated by sputum retention and ventilatory failure. This report demonstrates the successful perioperative management of an 11-yr-old boy with type II spinal muscular atrophy undergoing...

journal_title：British journal of anaesthesia

authors： Marchant WA,Fox R

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that ultrasound guidance for paediatric regional anaesthesia can improve the quality of upper extremity and neuraxial blocks. We therefore investigated whether ultrasound guidance for sciatic and femoral nerve blocks prolongs sensory blockade in comparison with nerve stimulator guid...

journal_title：British journal of anaesthesia

authors： Oberndorfer U,Marhofer P,Bösenberg A,Willschke H,Felfernig M,Weintraud M,Kapral S,Kettner SC

更新日期：2007-06-01 00:00:00

abstract：:Diaphragm strength can be assessed from twitch gastric (TwPgas), twitch oesophageal (TwPoes), and twitch transdiaphragmatic pressure (TwPdi) in response to phrenic nerve stimulation. This requires the passage of balloon catheters, which may be difficult. Changes in pressure measured at the mouth during phrenic nerve s...

journal_title：British journal of anaesthesia

authors： Mills GH,Ponte J,Hamnegard CH,Kyroussis D,Polkey MI,Moxham J,Green M

更新日期：2001-12-01 00:00:00

abstract：:This report describes the anaesthetic management of a ventricular arrhythmia-prone patient with a prolonged Q-T interval for closed reduction and wiring of a mandibular fracture. The patient was premedicated with propranolol and anaesthetized with isoflurane (inhalation). Documentation of heart rate v. Q-T interval re...

journal_title：British journal of anaesthesia

authors： Medak R,Benumof JL

更新日期：1983-04-01 00:00:00