Performing perioperative optimization of the high-risk surgical patient.

abstract：:The protein binding of four non-depolarizing neuromuscular blocking drugs-tubocurarine, fazadinium, pancuronium and Org NC45-was measured, in serum from normal patients and from patients with cirrhosis of the liver, by an ultracentrifugation method. The fraction bound to serum protein in normal patients was 56% for tu...

journal_title：British journal of anaesthesia

authors： Duvaldestin P,Henzel D

更新日期：1982-05-01 00:00:00

abstract：:We have studied the effect of tropisetron, a 5-HT3-receptor antagonist, on postoperative nausea, vomiting and pain in 54 patients, aged 50-83 yr, after major hip or knee surgery. The patients were given subarachnoid injection of plain 0.5% bupivacaine, mixed with preservative-free morphine 0.3 mg, for surgical and pos...

journal_title：British journal of anaesthesia

authors： Pitkänen MT,Niemi L,Tuominen MK,Rosenberg PH

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Owing to complexities of measuring dead space, ventilatory failure is difficult to quantify in critical care. A simple, novel index called ventilatory ratio (VR) can quantify ventilatory efficiency at the bedside. The study objectives were to evaluate physiological properties of VR and examine its clinical a...

journal_title：British journal of anaesthesia

authors： Sinha P,Singh S,Hardman JG,Bersten AD,Soni N,Australia and New Zealand Intensive Care Society Clinical Trials Group.

更新日期：2014-01-01 00:00:00

abstract：:Blood samples were obtained from a radial artery cannula in a 60-yr-old man during coronary artery surgery. Serum potassium concentrations of 9.3, 8.4, and 7.4 mmol litre(-1) were obtained. A simultaneous venous blood sample gave a serum potassium concentration of 4.4 mmol litre(-1). The ECG was unchanged. After the a...

journal_title：British journal of anaesthesia

authors： Mehta V,Ahmed Z

更新日期：2004-09-01 00:00:00

abstract：:The circulating blood volume (CBV) of critically ill patients may be difficult to estimate on the basis of history and physical examination. The aim of this study was to evaluate the ability of seven clinical signs and central venous pressure (CVP) to predict CBV in critically ill patients; CBV was evaluated with the ...

journal_title：British journal of anaesthesia

authors： Stéphan F,Flahault A,Dieudonné N,Hollande J,Paillard F,Bonnet F

更新日期：2001-06-01 00:00:00

abstract：:Single dose-response curves were determined for suxamethonium in neonates, infants and children during thiopentone-fentanyl-nitrous oxide anaesthesia. During onset of neuromuscular block, suxamethonium produced an increase in muscle tone which was greatest in neonates and infants. The dose-response curves for the thre...

journal_title：British journal of anaesthesia

authors： Meakin G,McKiernan EP,Morris P,Baker RD

更新日期：1989-06-01 00:00:00

abstract：:Mice, previously immunized with sheep erythrocytes, were anaesthetized with halothane and the splenic lymphoid cells were incubated with 3H-thymidine at 1-h intervals. Abiphasic response was observed; 0.9 and 1.5% halothane reduced 3H-thymidine incorporation into the primed lymphoid cells by 83 and 94% respectively, w...

journal_title：British journal of anaesthesia

authors： Bandoh T,Fujita T

更新日期：1976-12-01 00:00:00

abstract：:The serum concentrations of fazadinium and its metabolites were measured in 14 surgical patients with end-stage renal failure and in 11 patients free from kidney disease undergoing abdominal surgery. A two-compartment open model was used in the pharmacokinetic analysis of the data. The elimination half-life (T 1/2 bet...

journal_title：British journal of anaesthesia

authors： Duvaldestin P,Bertrand JC,Concina D,Henzel D,Lareng L,Desmonts JM

更新日期：1979-10-01 00:00:00

abstract：:We present a patient with a history of clomipramine-induced serotonin syndrome 5 yr prior who developed serotonin syndrome after a single dose of meperidine. This report heightens appreciation of population at risk and also recognition of potential toxicity in meperidine. ...

journal_title：British journal of anaesthesia

authors： Guo SL,Wu TJ,Liu CC,Ng CC,Chien CC,Sun HL

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Fibrinolysis contributes to coagulopathy after major trauma and surgery. We hypothesized that progressive haemodilution is responsible, at least in part, for increased fibrinolytic tendency of blood clot. METHODS:The study was performed in two parts. First, whole blood (WB) samples collected from six health...

journal_title：British journal of anaesthesia

authors： Bolliger D,Szlam F,Levy JH,Molinaro RJ,Tanaka KA

更新日期：2010-03-01 00:00:00

abstract：:It is known that propofol can have effects on atrioventricular node conduction. We report a case where administration of propofol was associated with termination of supraventricular tachycardia. Although a similar phenomenon has been reported in children, this is the first such case in an adult. ...

journal_title：British journal of anaesthesia

authors： Kannan S,Sherwood N

更新日期：2002-06-01 00:00:00

abstract：:We determined in 51 healthy patients undergoing body surface surgery the dose requirements for propofol, as part of a total i.v. anaesthesia technique with an alfentanil infusion. After premedication with temazepam, patients received alfentanil 50 micrograms kg-1 followed by an infusion of 50 micrograms kg-1 h-1. Pati...

journal_title：British journal of anaesthesia

authors： Richards MJ,Skues MA,Jarvis AP,Prys-Roberts C

更新日期：1990-08-01 00:00:00

abstract：:Cholinesterase phenotyping studies have been carried out in two laboratories on blood specimens from 28 patients shown to be susceptible to malignant hyperpyrexia. In contrast to previously published reports, no evidence could be found for an increase in the frequency of the E1u E1f genotype above that known to occur ...

journal_title：British journal of anaesthesia

authors： Evans RT,Iqbal J,Ellis FR,Halsall PJ,Dietz AA,Lubrano T,Rubinstein HM

更新日期：1981-03-01 00:00:00

abstract：:Bioactive substances in fresh frozen plasma (FFP) are considered to be related to adverse reactions after transfusion, particularly in septic or traumatized patients. Therefore, we analysed the concentration of various bioactive substances (histamine, eosinophil cationic protein, eosinophil protein X, myeloperoxidase ...

journal_title：British journal of anaesthesia

authors： Nielsen HJ,Reimert C,Pedersen AN,Dybkjoer E,Brünner N,Alsbjørn B,Skov PS

更新日期：1997-05-01 00:00:00

abstract：:Fires and explosions have occurred in the operating theatre for many years. Flammable inhalation anaesthetic agents were responsible for many incidents in the past, but these are no longer available in many countries. Other causes of fires and explosions still exist in the operating theatre and, from time to time, res...

journal_title：British journal of anaesthesia

authors： Macdonald AG

更新日期：1994-12-01 00:00:00

abstract：:Fresh gas flows of nitrous oxide, oxygen and halothane at 6, 3, 2 and 1 litre/min were introduced into a circle absorber system. Spontaneous respiration and IPPV were studied and a regression of inspired on delivered oxygen concentration % was calculated. The difference between delivered and inspired oxygen concentrat...

journal_title：British journal of anaesthesia

authors： Raymond JA

更新日期：1976-03-01 00:00:00

abstract：:The arterial to end-tidal PCO2 difference (PaCO2-PE'CO2) was measured in five anaesthetized dogs during controlled ventilation at 0.25 Hz (15 b.p.m.) and during high frequency jet ventilation at 1, 3 and 5 Hz. Because of the slow response of the infra-red carbon dioxide analyser, satisfactory recordings of end-tidal c...

journal_title：British journal of anaesthesia

authors： Mortimer AJ,Cannon DP,Sykes MK

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The revised cardiac risk index (RCRI) is associated strongly with increased cardiac ischaemic risk and perioperative death. Associations with non-cardiac morbidity in non-cardiac surgery have not been explored. In the elective orthopaedic surgical population, morbidity is common but preoperative predictors a...

journal_title：British journal of anaesthesia

authors： Ackland GL,Harris S,Ziabari Y,Grocott M,Mythen M,SOuRCe Investigators.

更新日期：2010-12-01 00:00:00

abstract：:The effect on intervillous blood flow of lumbar extradural analgesia for Caesarean section was studied in nine healthy women using xenon-133. Extradural anaesthesia was performed with lignocaine 1 1/2% 16--20 ml with adrenaline 5 microgram ml-1. Impairment of placental blood flow during the block was observed in seven...

journal_title：British journal of anaesthesia

authors： Jouppila R,Jouppila P,Kuikka J,Hollmén A

更新日期：1978-03-01 00:00:00

abstract：:We have studied the incidence of respiratory complications and hypoxic episodes during inhalation induction with isoflurane in 75 healthy unpremedicated children. Problems occurred less frequently when 4% isoflurane in oxygen was used from the outset than with traditional techniques using nitrous oxide and a gradually...

journal_title：British journal of anaesthesia

authors： Warde D,Nagi H,Raftery S

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) may affect blood coagulation. We studied the effects of a modified, balanced, high-molecular weight [mean molecular weight (MW) 550 kDa], high-substituted [degree of substitution (DS) 0.7] HES preparation (Hextend) on coagulation in patients undergoing major abdominal surgery. METH...

journal_title：British journal of anaesthesia

authors： Boldt J,Haisch G,Suttner S,Kumle B,Schellhaass A

更新日期：2002-11-01 00:00:00

abstract：:Cryoprecipitate, originally developed as a therapy for patients with antihaemophilic factor deficiency, or haemophilia A, has been in use for almost 50 yr. However, cryoprecipitate is no longer administered according to its original purpose, and is now most commonly used to replenish fibrinogen levels in patients with...

journal_title：British journal of anaesthesia

authors： Nascimento B,Goodnough LT,Levy JH

更新日期：2014-12-01 00:00:00

abstract：:We have examined the influence of electrical stimulation on caffeine-induced tension generation during contracture testing used to diagnose malignant hyperthermia. The cumulative contracture response to caffeine was compared in pairs of morphologically comparable muscle bundles obtained from the same patient. Only one...

journal_title：British journal of anaesthesia

authors： Heytens L,Martin JJ,Bossaert LL

更新日期：1992-07-01 00:00:00

abstract：:Recommendations for resuscitation of patients in early haemorrhagic shock, with active ongoing bleeding, have evolved in recent years. This review covers current theories of the pathophysiology of shock and recommended treatments, including damage control surgery, deliberate hypotensive management, administration of a...

journal_title：British journal of anaesthesia

authors： Dutton RP

更新日期：2012-12-01 00:00:00

abstract：:Skills related to driving, the ability to discriminate the fusion of flickering light, and hand and foot proprioception, were measured double-blind in 34 healthy volunteers before and after three doses of i.v. diazepam. The effects of diazepam were most harmful to co-ordination. With 0.15 mg/kg, 0.30 mg/kg and 0.45 mg...

journal_title：British journal of anaesthesia

authors： Korttila K,Linnoila M

更新日期：1975-04-01 00:00:00

abstract：:We studied the elimination rate of nitrous oxide in 36 patients undergoing orthopaedic surgery. They were allocated randomly to one of six groups which differed in time of nitrous oxide exposure and mode of ventilation. In order to simulate recovery conditions, nitrous oxide administration was discontinued after 30, 6...

journal_title：British journal of anaesthesia

authors： Einarsson S,Stenqvist O,Bengtsson A,Houltz E,Bengtson JP

更新日期：1993-08-01 00:00:00

abstract：:Bispectral index (BIS) was assessed as a monitor of depth of anaesthesia during fentanyl and midazolam anaesthesia for coronary bypass surgery. In 10 patients given morphine premedication, anaesthesia was induced with a combination of midazolam and fentanyl and thereafter maintained with a continuous infusion of a mix...

journal_title：British journal of anaesthesia

authors： Barr G,Anderson RE,Samuelsson S,Owall A,Jakobsson JG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Postoperative non-cardiac complication rates are as high as 11-28% after high-risk abdominal procedures. Emerging evidence indicates that postoperative cardiac troponin T elevations are associated with adverse outcome in non-cardiac surgery. The aim of this study was to determine the relationship between pos...

journal_title：British journal of anaesthesia

authors： Noordzij PG,van Geffen O,Dijkstra IM,Boerma D,Meinders AJ,Rettig TC,Eefting FD,van Loon D,van de Garde EM,van Dongen EP

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:During preanaesthesia evaluation at an outpatient clinic, information is summarized and structured. We aimed to estimate the effectiveness of this process by determining the proportion of patients presenting for surgery who had valid preoperative anaesthesia assessment records, and also the proportion of pat...

journal_title：British journal of anaesthesia

authors： van Klei WA,Peelen LM,Kruijswijk JE,van Wolfswinkel L

更新日期：2010-11-01 00:00:00

abstract：:Integrated electromyographic studies in burned patients, and in normal controls, during the administration of small doses of suxamethonium (0.1 or 0.2 mg kg-1) have shown that the level of paralysis and the duration of paralysis are significantly increased in burn patients and that the effect is greater with larger bu...

journal_title：British journal of anaesthesia

authors： Brown TC,Bell B

更新日期：1987-08-01 00:00:00