Remifentanil does not impair left ventricular systolic and diastolic function in young healthy patients.

abstract：:Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane...

journal_title：British journal of anaesthesia

authors： Wierda JM,Maestrone E,Bencini AF,Boyer A,Rashkovsky OM,Lip H,Karliczek R,Ket JM,Agoston S

更新日期：1989-02-01 00:00:00

abstract：:We have compared mivacurium and succinylcholine in 27 paediatric patients with mild (Child's A) to moderate (Child's B) liver disease undergoing oesophagogastroduodenoscopy (OGD) and injection of oesophageal varices, with 10 healthy children receiving mivacurium for ENT procedures. With mivacurium 0.2 mg kg-1, the sev...

journal_title：British journal of anaesthesia

authors： Green DW,Fisher M,Sockalingham I

更新日期：1998-09-01 00:00:00

abstract：:The Myotest is a new nerve stimulator which can give train-of-four, single twitch (1 and 10 s) and tetanic stimuli. Power is supplied by standard batteries, which allow 200 h effective use. The impulse is unipolar constant current, and the amplitude can be adjusted between 0 and 40 mA. These factors, plus the electron...

journal_title：British journal of anaesthesia

authors： Viby-Mogensen J,Hansen PH,Jørgensen BC,Ording H,Kann T,Fries B

更新日期：1980-05-01 00:00:00

abstract：:Maternal and umbilical venous serum naloxone concentrations were measured after the i.v. (30 mothers) or i.m. (seven mothers) injection of naloxone 400 micrograms. Following i.v. naloxone there was rapid transfer to the fetus and therapeutic plasma concentrations could be expected in 1 or 2 min. However, following i.m...

journal_title：British journal of anaesthesia

authors： Hibbard BM,Rosen M,Davies D

更新日期：1986-01-01 00:00:00

abstract：:To understand the cellular and molecular basis of the anaesthetic state, it is important to remember that, in the intact CNS, synapses operate within elaborate nerve networks. From the data presented above, it is evident that block of impulse conduction in presynaptic fibres does not explain the effects of most anesth...

journal_title：British journal of anaesthesia

authors： Pocock G,Richards CD

更新日期：1993-07-01 00:00:00

abstract：:We have compared the ability of naïve intubators to intubate the trachea using a laryngoscope and an intubating laryngeal mask airway (ILMA) after receiving basic training, in a randomized, prospective, crossover study in 60 patients. Ventilation of the lungs via the ILMA was also compared with ventilation with a face...

journal_title：British journal of anaesthesia

authors： Avidan MS,Harvey A,Chitkara N,Ponte J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Multi-injection targeted intracluster injection ultrasound-guided supraclavicular brachial plexus block has been advocated to provide a faster onset of anaesthesia compared with a double injection technique. By placing the needle within clusters of hypoechoic structures, corresponding to neural tissue, this ...

journal_title：British journal of anaesthesia

authors： Retter S,Szerb J,Kwofie K,Colp P,Sandeski R,Uppal V

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:In 2016, the World Health Organization (WHO) strongly recommended the use of a high fraction of inspired oxygen (FiO2) in adult patients undergoing general anaesthesia to reduce the risk of surgical site infection (SSI). Since then, further trials have been published, trials included previously have come und...

journal_title：British journal of anaesthesia

authors： de Jonge S,Egger M,Latif A,Loke YK,Berenholtz S,Boermeester M,Allegranzi B,Solomkin J

更新日期：2019-03-01 00:00:00

abstract：:Eighty-one consenting women undergoing elective Caesarean section under spinal anaesthesia were randomly divided into two groups. In Group O patients, ondansetron 4 mg was given intravenously at the end of the surgery and 8 mg added to the morphine solution in the PCA syringe. Patients in Group P received only morphin...

journal_title：British journal of anaesthesia

authors： Cherian VT,Smith I

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Circadian variation may affect many biological and pharmacological phenomena. METHODS:To assess circadian variations in labour pain perception, 222 consecutive nulliparous women with uncomplicated pregnancy, spontaneous labour, cervical dilatation (3-5 cm), ruptured membranes and normal fetal heart rate tra...

journal_title：British journal of anaesthesia

authors： Aya AG,Vialles N,Mangin R,Robert C,Ferrer JM,Ripart J,de La Coussaye JE

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Fluid administration to increase stroke volume index (SVi) is a cornerstone of haemodynamic resuscitation. We assessed the accuracy of SVi variation during a calibrated abdominal compression manoeuvre (ΔSVi-CAC) to predict fluid responsiveness in children. METHODS:Patients younger than 8 yr with acute circu...

journal_title：British journal of anaesthesia

authors： Jacquet-Lagrèze M,Tiberghien N,Evain JN,Hanna N,Courtil-Teyssedre S,Lilot M,Baudin F,Chardonnal L,Bompard D,Koffel C,Portefaix A,Javouhey E,Fellahi JL

更新日期：2018-12-01 00:00:00

abstract：:The role of endothelin-1, a potent vasoconstrictor released by vascular endothelium, in the vasoconstriction that develops after prolonged operations is not clear. This study was performed in order to determine if there was any relationship between endothelin-1 and the degree of vasoconstriction during prolonged plast...

journal_title：British journal of anaesthesia

authors： Tuominen HP,Svartling NE,Tikkanen IT,Saijonmaa O,Asko-Seljavaara S

更新日期：1995-06-01 00:00:00

abstract：:We describe the management of a patient with Eisenmenger's syndrome presenting for laparoscopic cholecystectomy. Of prime concern was maintenance of systemic vascular resistance and this was achieved using infusion of noradrenaline started before induction of anaesthesia and continued after operation. Avoidance of oth...

journal_title：British journal of anaesthesia

authors： Sammut MS,Paes ML

更新日期：1997-12-01 00:00:00

abstract：:The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...

journal_title：British journal of anaesthesia

authors： Dierking GW,Dahl JB,Kanstrup J,Dahl A,Kehlet H

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Thermal, mechanical, and electrical stimuli are often used in acute pain studies and cause qualitatively different pain sensations. Yet, the comparative electroencephalogram (EEG) changes caused by these stimuli have not been studied. We hypothesized that because these stimuli cause different pain sensations...

journal_title：British journal of anaesthesia

authors： Murrell JC,Mitchinson SL,Waters D,Johnson CB

更新日期：2007-03-01 00:00:00

abstract：:The cardiorespiratory effects of increasing respiratory frequency were investigated in two groups of dogs ventilated mechanically with a system which minimized apparatus and anatomical deadspace. In one group minute volume was constant whilst frequency was increased; in the second group minute volume was increased to ...

journal_title：British journal of anaesthesia

authors： Chakrabarti MK,Sykes MK

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Dynamic variables reliably predict fluid responsiveness (FR) in adults, but no data are available regarding their performance in infants. The aim of this prospective study was to assess whether pulse pressure variation (PPV) and stroke volume variation (SVV), in contrast to central venous pressure (CVP) and ...

journal_title：British journal of anaesthesia

authors： Renner J,Broch O,Duetschke P,Scheewe J,Höcker J,Moseby M,Jung O,Bein B

更新日期：2012-01-01 00:00:00

abstract：:A double-blind crossover volunteer trial has been carried out to determine if oral doxapram reduces the respiratory depression caused by morphine 0.12 mg kg-1 i.m. Doxapram was given to the subjects 90 min before the morphine and significantly reduced the displacement of the ventilatory response to carbon dioxide caus...

journal_title：British journal of anaesthesia

authors： Randall NP,Pleuvry BJ,Fazackerley EJ,Modla CY,Prescott LF,Healy TE

更新日期：1989-02-01 00:00:00

abstract：:The value of the continuous monitoring of end-tidal carbon dioxide concentration as an indicator of the acute intraoperative interruption of pulmonary blood flow, in patients with pre-existing restrictions of pulmonary blood flow undergoing closed heart surgery, is illustrated by two case reports. Decreases in end-tid...

journal_title：British journal of anaesthesia

authors： Schuller JL,Bovill JG,Nijveld A

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:There is considerable evidence that the use of tidal volumes <6 ml kg(-1) predicted body weight (PBW) reduces mortality in mechanically ventilated patients. We evaluated the effectiveness of using a large screen displaying delivered tidal volume in ml kg(-1) (PBW) for reducing tidal volumes. METHODS:We asse...

journal_title：British journal of anaesthesia

authors： Bourdeaux CP,Birnie K,Trickey A,Thomas MJ,Sterne J,Donovan JL,Benger J,Brandling J,Gould TH

更新日期：2015-08-01 00:00:00

abstract：:We have studied the efficacy of preoxygenation using the Triservice Anaesthetic Apparatus (TSA) in healthy patients and found it to be unsatisfactory. An alternative technique suitable for field use was explored. The Mapleson D system (Bain) was found to be suitable for preoxygenation with a fresh gas flow of only 4 l...

journal_title：British journal of anaesthesia

authors： Lowe DM,McFadzean W

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Increasing numbers of older patients prescribed clopidogrel are presenting for urgent hip fracture surgery. Best practice for the management of clopidogrel therapy is unknown, although delays to surgery are associated with increased mortality. We investigated the influence of perioperative management of clop...

journal_title：British journal of anaesthesia

authors： Collyer TC,Reynolds HC,Truyens E,Kilshaw L,Corcoran T

更新日期：2011-12-01 00:00:00

abstract：:A genetic disorder of the calcium releasing ryanodine receptor has recently been postulated in malignant hyperthermia (MH) and ryanodine-induced contractures differ between subjects who are malignant hyperthermia susceptible (MHS) and non-susceptible (MHN). We tested 39 patients from 26 families for MH, using the proc...

journal_title：British journal of anaesthesia

authors： Lenzen C,Roewer N,Wappler F,Scholz J,Kahl J,Blank M,Rumberger E,Schulte am Esch J

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:The objective of this study was to develop a pharmacokinetic (PK) model to characterize the influence of obesity on propofol PK parameters. METHODS:Nineteen obese ASA II patients undergoing bariatric surgery were studied. Patients received propofol 2 mg kg(-1) bolus dose followed by a 5-20-40-120 min, 10-8-...

journal_title：British journal of anaesthesia

authors： Cortínez LI,Anderson BJ,Penna A,Olivares L,Muñoz HR,Holford NH,Struys MM,Sepulveda P

更新日期：2010-10-01 00:00:00

abstract：:We have examined dimethylthiourea, a potent scavenger of free radicals, for its anaesthetic properties in mice and rats. In mice, dimethylthiourea abolished the righting reflex at intraperitoneal doses greater than 1.5 mg g-1 bodyweight; in rats, it decreased the MAC value for isoflurane in a dose-dependent fashion. D...

journal_title：British journal of anaesthesia

authors： Koblin DD,Laster MJ,Liu J

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Desflurane (DES)-induced preconditioning is mediated by large-conductance calcium-activated potassium channels (BK(Ca)). Whether BK(Ca) are involved in anaesthetic-induced post-conditioning is unknown. We tested the hypothesis that DES-induced post-conditioning is mediated by BK(Ca) upstream of the mitochond...

journal_title：British journal of anaesthesia

authors： Stumpner J,Lange M,Beck A,Smul TM,Lotz CA,Kehl F,Roewer N,Redel A

更新日期：2012-04-01 00:00:00

abstract：:Using cats with chronically implanted brain electrodes, we have compared the effects of propofol on CNS electrical activities with those of thiopentone. Ten cats were allocated to receive either propofol (n = 5) or thiopentone (n = 5). Cats were anaesthetized initially with 4% halothane in oxygen. The trachea was intu...

journal_title：British journal of anaesthesia

authors： Tomoda K,Shingu K,Osawa M,Murakawa M,Mori K

更新日期：1993-09-01 00:00:00

abstract：:Falls are a known public health problem, and there is increasing recognition of the importance of perioperative falls for risk prediction and quality assessment. Our objective was to review existing literature regarding the occurrence, injuries, and risk factors of preoperative and postoperative falls. A systematized ...

journal_title：British journal of anaesthesia

authors： Kronzer VL,Wildes TM,Stark SL,Avidan MS

更新日期：2016-12-01 00:00:00

abstract：:Ketamine, as the sole anaesthetic agent, was assessed in a double-blind study of 135 female patients who underwent laparoscopic sterilization. The patients were allocated randomly to one of four groups according to the type (pentobarbitone or droperidol) and route (i.v. or i.m.) of premedication. In addition all the p...

journal_title：British journal of anaesthesia

authors： Figallo EM,Casali H,McKenzie R,Tantisira B,Wadhwa RK,Taylor FH

更新日期：1977-11-01 00:00:00

abstract：:The effects of bolus doses of phenoperidine 1-2 mg i.v. either alone, or combined with pancuronium 2-4 mg, were investigated in seven patients in traumatic coma. Phenoperidine alone significantly reduced mean arterial pressure (MAP) by a mean (+/- SEM) of 13.2 (+/- 2.8) mm Hg. Overall there was no significant change i...

journal_title：British journal of anaesthesia

authors： Bingham RM,Hinds CJ

更新日期：1987-05-01 00:00:00