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Diagnostic accuracy of a calibrated abdominal compression to predict fluid responsiveness in children.

Abstract：

BACKGROUND:Fluid administration to increase stroke volume index (SVi) is a cornerstone of haemodynamic resuscitation. We assessed the accuracy of SVi variation during a calibrated abdominal compression manoeuvre (ΔSVi-CAC) to predict fluid responsiveness in children. METHODS:Patients younger than 8 yr with acute circulatory failure, regardless of their ventilation status, were selected. SVi, calculated as the average of five velocity-time integrals multiplied by the left ventricular outflow tract surface area, was recorded at four different steps: baseline, after an abdominal compression with a calibrated pressure of 25 mm Hg, after return to baseline, and then after a volume expansion (VE) of 10 ml kg-1 lactated Ringer solution over 10 min. Patients were classified as responders if SVi variation after volume expansion (ΔSVi-VE) increased by at least 15%. RESULTS:The 39 children included had a median [inter-quartile range (IQR)] age of 9 [5-31] months. Twenty patients were fluid responders and 19 were non-responders. ΔSVi-CAC correlated with ΔSVi-VE (r=0.829; P<0.001). The area under the receiver operating characteristic curve (ROCAUC) was 0.94 [95% confidence interval (CI), 0.85-0.99]. The best threshold for ΔSVi-CAC was 11% with a specificity of 95% [95% CI, 84-100] and a sensitivity of 75% [95% CI, 55-95]. ROCAUC of respiratory variation of IVC diameter (ΔIVC) was 0.53 [95% CI, 0.32-0.72]. CONCLUSION:ΔSVi-CAC during abdominal compression was a reliable method to predict fluid responsiveness in children with acute circulatory failure regardless of their ventilation status. CLINICAL TRIALS REGISTRATION:CPP Lyon sud est II: n° ANSM 2015-A00388-41 Clinicaltrial.gov: NCT02505646.

journal_name

Br J Anaesth

journal_title

British journal of anaesthesia

authors

Jacquet-Lagrèze M,Tiberghien N,Evain JN,Hanna N,Courtil-Teyssedre S,Lilot M,Baudin F,Chardonnal L,Bompard D,Koffel C,Portefaix A,Javouhey E,Fellahi JL

doi

10.1016/j.bja.2018.06.030

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

1323-1331

issue

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(18)30635-4

journal_volume

121

pub_type

杂志文章

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Diagnostic accuracy of a calibrated abdominal compression to predict fluid responsiveness in children.