Morphological and biochemical defects in muscles of human carriers of the malignant hyperthermia syndrome.

abstract：BACKGROUND:A significantly increased risk of acute kidney injury (AKI) with the prophylactic use of aprotinin has been reported in adults undergoing cardiac surgery, but not in children. Blood product transfusions have also been shown to carry an independent risk of AKI. The present study assessed associations between ...

journal_title：British journal of anaesthesia

authors： Bojan M,Vicca S,Boulat C,Gioanni S,Pouard P

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Recent studies have concluded that i.v. dexamethasone can prolong the duration of peripheral nerve blockade. We hypothesized that a 4 mg dose would equally prolong the duration of psoas compartment blocks (PCBs) when compared with 8 mg, and that both doses would prolong the duration when compared with placeb...

journal_title：British journal of anaesthesia

authors： Turner JD,Dobson SW,Weller RS,Russell GB,Henshaw DS

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Interscalene brachial plexus block (ISBPB) is an effective nerve block for shoulder surgery. However, a 100% incidence of phrenic nerve palsy limits the application of ISBPB for patients with limited pulmonary reserve. We examined the incidence of phrenic nerve palsy with a low-volume ISBPB compared with a s...

journal_title：British journal of anaesthesia

authors： Riazi S,Carmichael N,Awad I,Holtby RM,McCartney CJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Circadian variation may affect many biological and pharmacological phenomena. METHODS:To assess circadian variations in labour pain perception, 222 consecutive nulliparous women with uncomplicated pregnancy, spontaneous labour, cervical dilatation (3-5 cm), ruptured membranes and normal fetal heart rate tra...

journal_title：British journal of anaesthesia

authors： Aya AG,Vialles N,Mangin R,Robert C,Ferrer JM,Ripart J,de La Coussaye JE

更新日期：2004-09-01 00:00:00

abstract：:The safety of aspirin therapy in neuraxial anaesthesia has been historically questioned, and the current recommendations are still heterogeneous. A comprehensive review of clinical evidence and a comparative analysis of European and American guidelines were performed. Low-dose aspirin produces a selective, complete an...

journal_title：British journal of anaesthesia

authors： Vela Vásquez RS,Peláez Romero R

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Patient dissatisfaction has been previously associated with motor block in shoulder surgery patients receiving brachial plexus block. For elective minor wrist and hand surgery, we tested whether a regional block accelerating the early return of upper extremity motor function would improve patient satisfactio...

journal_title：British journal of anaesthesia

authors： Fredrickson MJ,Wolstencroft PJ,Chinchanwala S,Boland MR

更新日期：2012-11-01 00:00:00

abstract：:The influence of sodium nitroprusside (SNP) on mitochondrial respiration was examined in rat liver mitochondria. The addition of SNP 1 mmol litre-1 during state 3 respiration inhibited the oxygen uptake by 63.4%. A mixture of SNP 1 mmol litre-1 and glutathione (GSH) 1 mmol litre-1 inhibited the oxygen uptake more mark...

journal_title：British journal of anaesthesia

authors： Nakamura S,Shin T,Hirokata Y,Shigematsu A

更新日期：1977-12-01 00:00:00

abstract：:We have evaluated the effect of delivering nitric oxide using a continuous flow system (CFS) or two commercially available proportional gas injection systems (PGIS), Nodomo (Dräger, Lübeck, Germany) and Pulmonox-Mini (Messer Griesheim Austria, Gumpoldskirchen, Austria) on measured and simulated concentrations of nitri...

journal_title：British journal of anaesthesia

authors： Hiesmayr MJ,Neugebauer T,Lassnigg A,Steltzer H,Haider W,Gilly H

更新日期：1998-10-01 00:00:00

abstract：:Lung function and clinical evidence of muscle weakness were assessed in 12 ASA I patients who received vecuronium 0.01 mg kg-1 pretreatment as a part of their anaesthetic management, before and 3 min after pretreatment. Most patients demonstrated ptosis and diplopia, while five of the 12 were unable to raise the head ...

journal_title：British journal of anaesthesia

authors： Mahajan RP,Laverty J

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:A multidisciplinary approach to improve postoperative outcomes in frail elderly patients is gaining interest. Multidisciplinary team care should be targeted at complex patients at high risk for adverse postoperative outcome to limit the strain on available resources and to prevent an unnecessary increase in ...

journal_title：British journal of anaesthesia

authors： Verwijmeren L,Peelen LM,van Klei WA,Daeter EJ,van Dongen EPA,Noordzij PG

更新日期：2020-02-14 00:00:00

abstract：:We report the case of a morbidly obese patient who developed rhabdomyolysis with acute renal failure, hepatic dysfunction, and an increase of cardiac troponin-1 after total knee arthroplasty. Postoperative rhabdomyolysis has a wide range of triggers and differential diagnoses that should be considered by the anaesthes...

journal_title：British journal of anaesthesia

authors： Karcher C,Dieterich HJ,Schroeder TH

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate whether reversal of rocuronium-induced neuromuscular blockade with sugammadex reduced the incidence of residual blockade and facilitated operating room discharge readiness. METHODS:Adult patients undergoing abdominal surgery received rocuronium, followed by randomized allocat...

journal_title：British journal of anaesthesia

authors： Brueckmann B,Sasaki N,Grobara P,Li MK,Woo T,de Bie J,Maktabi M,Lee J,Kwo J,Pino R,Sabouri AS,McGovern F,Staehr-Rye AK,Eikermann M

更新日期：2015-11-01 00:00:00

abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Statistical analysis suggests t...

journal_title：British journal of anaesthesia

authors： Saitoh Y,Kaneda K,Hattori H,Nakajima H,Murakawa M

更新日期：2019-01-01 00:00:00

abstract：:Regional haemodynamic control by the cardiovascular baroreceptors was examined in dogs anaesthetized with 1 + MAC halothane in oxygen (1%). The open-loop relationships between carotid sinus pressure (CSP) and regional haemodynamics in the iliac, renal, mesenteric, aortic and coeliac beds were examined before vagotomy,...

journal_title：British journal of anaesthesia

authors： Bagshaw RJ,Cox RH

更新日期：1977-06-01 00:00:00

abstract：:Cobra venom consists of a neurotoxin which is responsible for respiratory paralysis simulating that associated with a non-depolarizing muscle relaxant. A combination of artificial respiration and neostigmine has been useful in resuscitating a child bitten by a snake. ...

journal_title：British journal of anaesthesia

authors： Naphade RW,Shetti RN

更新日期：1977-10-01 00:00:00

abstract：:A 39-year-old male suffered a closed chest deceleration injury. He presented with clinical and radiological signs consistent with trauma to the thoracic aorta, but also developed sinus bradycardia which was relieved by drainage of a haemothorax. The possible mechanisms of the changes in heart rate are discussed and di...

journal_title：British journal of anaesthesia

authors： Kong RS,Wood PR

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Pressure recording analytical method (PRAM) is a novel, arterial pulse contour-based method for measuring cardiac output (CO). Validation studies of PRAM in children are few, and have not assessed both absolute accuracy and ability to track changes in CO across a broad case mix. We aimed to compare CO as mea...

journal_title：British journal of anaesthesia

authors： Saxena R,Durward A,Puppala NK,Murdoch IA,Tibby SM

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Dynamic variables reliably predict fluid responsiveness (FR) in adults, but no data are available regarding their performance in infants. The aim of this prospective study was to assess whether pulse pressure variation (PPV) and stroke volume variation (SVV), in contrast to central venous pressure (CVP) and ...

journal_title：British journal of anaesthesia

authors： Renner J,Broch O,Duetschke P,Scheewe J,Höcker J,Moseby M,Jung O,Bein B

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Lower thoracic epidural anaesthesia and analgesia (EDA) has gained increasing importance in perioperative pain therapy. The loss-of-resistance technique used to identify the epidural space is thought to rely on the penetration of the ligamentum flavum. Investigations at the cervical and lumbar regions have d...

journal_title：British journal of anaesthesia

authors： Lirk P,Colvin J,Steger B,Colvin HP,Keller C,Rieder J,Kolbitsch C,Moriggl B

更新日期：2005-06-01 00:00:00

abstract：:Intracuff pressure (c.p.) was measured continuously in 12 patients during prolonged periods of tracheal intubation. High residual volume--low pressure (floppy) and low residual volume--high pressure (conventional) cuffs were studied. The mean baseline c.p. at minimal occluding pressure was significantly smaller in flo...

journal_title：British journal of anaesthesia

authors： Jacobson L,Greenbaum R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Even mild perioperative hypothermia is associated with several severe adverse effects. Resistive heating has possible advantages compared with other active warming systems because it can heat several fields independently. To assess this new warming system, we measured core temperature in patients during surg...

journal_title：British journal of anaesthesia

authors： Matsuzaki Y,Matsukawa T,Ohki K,Yamamoto Y,Nakamura M,Oshibuchi T

更新日期：2003-05-01 00:00:00

abstract：:Dose-response relationships for the antagonism of intermediate-acting neuromuscular blocking agents have not been evaluated previously in children. We have examined the dose-response relationships for neostigmine antagonism of 90% rocuronium-induced neuromuscular block in children and adults, during nitrous oxide-1 MA...

journal_title：British journal of anaesthesia

authors： Abdulatif M,Mowafi H,al-Ghamdi A,el-Sanabary M

更新日期：1996-12-01 00:00:00

abstract：:In 1849 John Snow, already the leading anaesthetic practitioner and innovator of his day, made a historic contribution to the epidemiology of infectious disease by his famous study of the distribution of cholera around the area of Broad Street in London. We report on our experience as anaesthetists in a field hospital...

journal_title：British journal of anaesthesia

authors： Ginosar Y,Shapira SC

更新日期：1995-12-01 00:00:00

abstract：:Integrated electromyographic studies in burned patients, and in normal controls, during the administration of small doses of suxamethonium (0.1 or 0.2 mg kg-1) have shown that the level of paralysis and the duration of paralysis are significantly increased in burn patients and that the effect is greater with larger bu...

journal_title：British journal of anaesthesia

authors： Brown TC,Bell B

更新日期：1987-08-01 00:00:00

abstract：:Seventy-two adult surgical patients were studied to compare neuromuscular and cardiovascular effects of mivacurium chloride during nitrous oxide-fentanyl-thiopentone (BAL group) or nitrous oxide-halothane (HAL group) anaesthesia. Eighteen patients in the BAL group received an initial bolus of mivacurium, either the ED...

journal_title：British journal of anaesthesia

authors： From RP,Pearson KS,Choi WW,Abou-Donia M,Sokoll MD

更新日期：1990-02-01 00:00:00

abstract：:Fires and explosions have occurred in the operating theatre for many years. Flammable inhalation anaesthetic agents were responsible for many incidents in the past, but these are no longer available in many countries. Other causes of fires and explosions still exist in the operating theatre and, from time to time, res...

journal_title：British journal of anaesthesia

authors： Macdonald AG

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:There has been a renewed interest in nitric oxide donor drugs, such as nitroglycerin, delivered by the inhalational route for treatment of pulmonary arterial hypertension (PAH). We investigated the acute effects of inhaled nitroglycerin on pulmonary and systemic haemodynamics in children with PAH associated ...

journal_title：British journal of anaesthesia

authors： Goyal P,Kiran U,Chauhan S,Juneja R,Choudhary M

更新日期：2006-08-01 00:00:00

abstract：Background:. Missense variants in the ryanodine receptor 1 gene ( RYR1 ) are associated with malignant hyperthermia but only a minority of these have met the criteria for use in predictive DNA diagnosis. We examined the utility of a simplified method of segregation analysis and a functional assay for determining the pa...

journal_title：British journal of anaesthesia

authors： Merritt A,Booms P,Shaw MA,Miller DM,Daly C,Bilmen JG,Stowell KM,Allen PD,Steele DS,Hopkins PM

更新日期：2017-04-01 00:00:00

abstract：:A 72-yr-old patient was to undergo a left lumbar plexus block by the posterior approach to achieve postoperative analgesia after hip replacement. The block failed after three unsuccessful attempts to identify nerve structures and a fascia iliaca compartment block was performed. Postoperatively the patient received eno...

journal_title：British journal of anaesthesia

authors： Aveline C,Bonnet F

更新日期：2004-10-01 00:00:00

abstract：:Units for the investigation of susceptibility to malignant hyperthermia (MH) were set up in Denmark in 1977 and in Sweden in 1981. Two hundred and ten patients from 76 families have been investigated. The diagnosis of MH susceptibility (MHS) was made by in vitro exposure of muscle from vastus medialis to halothane and...

journal_title：British journal of anaesthesia

authors： Ording H,Ranklev E,Fletcher R

更新日期：1984-11-01 00:00:00