Isobutene formation during halothane anaesthesia in man.

abstract：BACKGROUND:Neurological deficit after repair of a thoracic or thoracoabdominal aortic aneurysm (TAA/TAAA) remains a devastating complication. The aim of our study was to investigate the clinical value of biochemical markers [S-100B, neurone-specific enolase (NSE) and lactate dehydrogenase (LD)], evoked potentials and t...

journal_title：British journal of anaesthesia

authors： Lases EC,Schepens MA,Haas FJ,Aarts LP,ter Beek HT,van Dongen EP,Siegers HP,van der Tweel I,Boezeman EH

更新日期：2005-11-01 00:00:00

abstract：:Most human phenotypic characteristics are determined by the interplay of environmental factors (whether external, or related to the internal milieu) with the unique genetic attributes of the individual. The same is true for predisposition to and outcome from most disease states, with acute brain injury being no except...

journal_title：British journal of anaesthesia

authors： Wilson M,Montgomery H

更新日期：2007-07-01 00:00:00

abstract：:We evaluated prospectively the use of Gram staining of protected pulmonary specimens to allow the early diagnosis of ventilator-associated pneumonia (VAP), compared with the use of 60 bronchoscopic protected specimen brushes (PSB) and 126 blinded plugged telescopic catheters (PTC) obtained from 134 patients. Gram stai...

journal_title：British journal of anaesthesia

authors： Mimoz O,Karim A,Mazoit JX,Edouard A,Leprince S,Nordmann P

更新日期：2000-11-01 00:00:00

abstract：:Thrombelastography (TEG) correlates with postoperative chest drain output in patients undergoing cardiopulmonary bypass (CPB). In vitro incubation with heparinase allows TEG monitoring during CPB, despite heparin anticoagulation. Hypothermia impairs coagulation, but these effects cannot be assessed by standard coagula...

journal_title：British journal of anaesthesia

authors： Kettner SC,Kozek SA,Groetzner JP,Gonano C,Schellongowski A,Kucera M,Zimpfer M

更新日期：1998-03-01 00:00:00

abstract：:We have measured in 38 patients the plasma concentration profile of atracurium and its effect on the electromyographic first response of the train-of-four. One of three techniques was used to supplement anaesthesia with 66% nitrous oxide in oxygen, 0.9% isoflurane (end-tidal), 0.5% halothane (end-tidal) or midazolam 3...

journal_title：British journal of anaesthesia

authors： Parker CJ,Hunter JM,Snowdon SL

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Abnormal serum sodium concentrations are common in patients presenting for surgery. It remains unclear whether these abnormalities are independent risk factors for postoperative mortality. METHODS:This is a secondary analysis of the European Surgical Outcome Study (EuSOS) that provided data describing 46 53...

journal_title：British journal of anaesthesia

authors： Cecconi M,Hochrieser H,Chew M,Grocott M,Hoeft A,Hoste A,Jammer I,Posch M,Metnitz P,Pelosi P,Moreno R,Pearse RM,Vincent JL,Rhodes A,European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society o

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Propofol use during sedation for colonoscopy can result in cardiopulmonary complications. Intravenous lidocaine can alleviate visceral pain and decrease propofol requirements during surgery. We tested the hypothesis that i.v. lidocaine reduces propofol requirements during colonoscopy and improves post-colono...

journal_title：British journal of anaesthesia

authors： Forster C,Vanhaudenhuyse A,Gast P,Louis E,Hick G,Brichant JF,Joris J

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Increasing numbers of older patients prescribed clopidogrel are presenting for urgent hip fracture surgery. Best practice for the management of clopidogrel therapy is unknown, although delays to surgery are associated with increased mortality. We investigated the influence of perioperative management of clop...

journal_title：British journal of anaesthesia

authors： Collyer TC,Reynolds HC,Truyens E,Kilshaw L,Corcoran T

更新日期：2011-12-01 00:00:00

abstract：:The experimental effort that has been expended in investigating the effects of general anaesthetics on LGICs has been enormous over the past decade. Members of all three LGIC superfamilies have been examined using electrophysiological techniques. Anaesthetics that have been examined include volatile anaesthetics, gase...

journal_title：British journal of anaesthesia

authors： Dilger JP

更新日期：2002-07-01 00:00:00

abstract：:The analgesic effect of subanaesthetic concentrations of ether, trichloroethylene, methoxyflurane and halothane has been investigated previously using either clinical assessment or pain threshold measurements, but with conflicting results. The purpose of the present study was to evaluate the analgesic effect of isoflu...

journal_title：British journal of anaesthesia

authors： Petersen-Felix S,Arendt-Nielsen L,Bak P,Roth D,Fischer M,Bjerring P,Zbinden AM

更新日期：1995-07-01 00:00:00

abstract：:We have tested the hypothesis that intradermal testing is a more effective method for determining the drug responsible for anaesthetic anaphylactic reactions than prick testing in 212 consecutive patients, aged more than 10 yr, referred to an anaesthetic allergy clinic over a 4-yr period. The study was a prospective, ...

journal_title：British journal of anaesthesia

authors： Fisher MM,Bowey CJ

更新日期：1997-07-01 00:00:00

abstract：:The face-grafting techniques are innovative and highly complex, requiring well-defined organization of all the teams involved. Subsequent to the first report in France in 2005, there have been 17 facial allograft transplantations performed worldwide. We describe anaesthesia and postoperative management, and the proble...

journal_title：British journal of anaesthesia

authors： Sedaghati-nia A,Gilton A,Liger C,Binhas M,Cook F,Ait-Mammar B,Scherrer E,Hivelin M,Lantieri L,Marty J,Plaud B

更新日期：2013-10-01 00:00:00

abstract：:Eight patients with a history of failed tracheal intubation during pregnancy were investigated by x-ray laryngoscopy after delivery. Partial elevation of the epiglottis with no view of glottic structures was found in five patients who were therefore considered to still present difficulty. In each of these five patient...

journal_title：British journal of anaesthesia

authors： Fahy L,Horton WA,Charters P

更新日期：1990-12-01 00:00:00

abstract：:The Walton-Brodie strain gauge arch is an instrument that quantitatively measures CF. Like many methods, the strain gauge arch is affected by loading conditions and heart rate. Nevertheless, this methodology, when properly used, has proved very useful in describing the direct action of anaesthetic drugs. Knowledge fro...

journal_title：British journal of anaesthesia

authors： Reves JG,Pruett JK

更新日期：1988-01-01 00:00:00

abstract：:Patients with Munchausen's syndrome often undergo multiple surgical operations under general anaesthesia. They tend to have multiple exposures to routinely used anaesthetic agents. A patient with Munchausen's syndrome who developed an anaphylactoid reaction to thiopentone is described and the importance of obtaining p...

journal_title：British journal of anaesthesia

authors： Frater RA,Lew JK

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Parecoxib, a cyclo oxygenase-2 inhibiting non-steroidal anti-inflammatory drug, has been widely used for postoperative analgesia. Our aim was to quantify the benefit of a single dose after coronary artery bypass grafting. METHODS:The investigation was carried out as a randomized double blind placebo control...

journal_title：British journal of anaesthesia

authors： Khalil MW,Chaterjee A,Macbryde G,Sarkar PK,Marks RR

更新日期：2006-02-01 00:00:00

abstract：:The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...

journal_title：British journal of anaesthesia

authors： Dierking GW,Dahl JB,Kanstrup J,Dahl A,Kehlet H

更新日期：1992-04-01 00:00:00

abstract：:Human error poses significant risk for hospitalized patients causing an estimated 100,000 to 400,000 deaths in the USA annually. Medication errors contribute, with error occurring in 5.3% of medication administrations during surgery. In this study 70.3% of medication errors were deemed preventable. Given the paucity o...

journal_title：British journal of anaesthesia

authors： Wahr JA,Abernathy JH 3rd,Lazarra EH,Keebler JR,Wall MH,Lynch I,Wolfe R,Cooper RL

更新日期：2017-01-01 00:00:00

abstract：:We have compared iontophoretically and locally applied lidocaine for relief of pain on propofol injection. Pain was assessed on insertion of a 20-gauge i.v. cannula and at 10-s intervals for 30 s after injection of propofol. Pain scores on cannulation were significantly less in the iontophoresis group (median 1.1) tha...

journal_title：British journal of anaesthesia

authors： Sadler PJ,Thompson HM,Maslowski P,Liddle A,Rowbotham DJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:The safety of performing spinal anaesthesia for both patients and anaesthetists alike in the presence of active infection with the novel coronavirus disease 2019 (COVID-19) is unclear. Here, we report the clinical characteristics and outcomes for both patients with COVID-19 and the anaesthetists who provided...

journal_title：British journal of anaesthesia

authors： Zhong Q,Liu YY,Luo Q,Zou YF,Jiang HX,Li H,Zhang JJ,Li Z,Yang X,Ma M,Tang LJ,Chen YY,Zheng F,Ke JJ,Zhang ZZ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Cut-off points (CPs) of the numeric rating scale (NRS 0-10) are regularly used in postoperative pain treatment. However, there is insufficient evidence to identify the optimal CP between mild and moderate pain. METHODS:A total of 435 patients undergoing general, trauma, or oral and maxillofacial surgery wer...

journal_title：British journal of anaesthesia

authors： Gerbershagen HJ,Rothaug J,Kalkman CJ,Meissner W

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Owing to complexities of measuring dead space, ventilatory failure is difficult to quantify in critical care. A simple, novel index called ventilatory ratio (VR) can quantify ventilatory efficiency at the bedside. The study objectives were to evaluate physiological properties of VR and examine its clinical a...

journal_title：British journal of anaesthesia

authors： Sinha P,Singh S,Hardman JG,Bersten AD,Soni N,Australia and New Zealand Intensive Care Society Clinical Trials Group.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:There has been increasing use of invasive techniques, such as extracorporeal organ support, in intensive care units (ICU), and declining autopsy rates. Thus, new measures are needed to maintain high-quality standards. We investigated the potential of computed tomography (CT)-based virtual autopsy to substitu...

journal_title：British journal of anaesthesia

authors： Wichmann D,Heinemann A,Zähler S,Vogel H,Höpker W,Püschel K,Kluge S

更新日期：2018-06-01 00:00:00

abstract：:We have investigated the effect of dopamine and dopexamine on the isolated perfused rat kidney. After an equilibration period of 20 min and two control periods of 10 min, dopexamine 1.0, 2.5 or 4.0 micrograms kg-1 min-1 or dopamine 2.0 micrograms kg-1 min-1 were perfused for a further 40 min in random order. Renal blo...

journal_title：British journal of anaesthesia

authors： Kirchhoff K,Leuwer M,Thum P,Bornscheuer A,Piepenbrock S

更新日期：1999-12-01 00:00:00

abstract：:We have investigated the value of lower oesophageal contractility (LOC) in detecting awareness during anaesthesia in 20 human volunteer patients. LOC was measured either with subjects awake or after induction with propofol, during induction with propofol, and then as consciousness returned. Statistically significant c...

journal_title：British journal of anaesthesia

authors： Isaac PA,Rosen M

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Balloon dilatational tracheostomy using the Ciaglia Blue Dolphin device has recently been introduced as a modification of the Ciaglia technique. The aim of this study was to compare the new Dolphin system with the single-step dilatational tracheostomy (Ciaglia Blue Rhino) in intensive care unit (ICU) patient...

journal_title：British journal of anaesthesia

authors： Cianchi G,Zagli G,Bonizzoli M,Batacchi S,Cammelli R,Biondi S,Spina R,Peris A

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:We investigated the extent and frequency of dose errors and treatment delays made as a consequence of preparing drug infusions at the bedside, rather than using pre-filled syringes. METHODS:Forty-eight nurses with critical care experience volunteered to take part in this randomized, blinded, controlled stud...

journal_title：British journal of anaesthesia

authors： Adapa RM,Mani V,Murray LJ,Degnan BA,Ercole A,Cadman B,Williams CE,Gupta AK,Wheeler DW

更新日期：2012-11-01 00:00:00

abstract：:Single dose-response curves were determined for suxamethonium in neonates, infants and children during thiopentone-fentanyl-nitrous oxide anaesthesia. During onset of neuromuscular block, suxamethonium produced an increase in muscle tone which was greatest in neonates and infants. The dose-response curves for the thre...

journal_title：British journal of anaesthesia

authors： Meakin G,McKiernan EP,Morris P,Baker RD

更新日期：1989-06-01 00:00:00

abstract：:We tested the hypothesis that premedication with i.m. midazolam decreases core temperature dose-dependently. We studied six male volunteers, in random order, on 3 days: (1) no midazolam administration (control day), (2) midazolam 0.025 mg kg-1 i.m., (3) midazolam 0.075 mg kg-1 i.m. On the first day, subjects were main...

journal_title：British journal of anaesthesia

authors： Matsukawa T,Hanagata K,Ozaki M,Iwashita H,Koshimizu M,Kumazawa T

更新日期：1997-04-01 00:00:00

abstract：:The study was performed to determine the ED50 and ED95 of a continuous infusion of the emulsion formulation of propofol during 67% nitrous oxide anaesthesia in 57 patients premedicated with morphine sulphate 0.15 mg kg-1. Anaesthesia was induced with propofol 2 mg kg-1, and maintained before incision with a fixed-rate...

journal_title：British journal of anaesthesia

authors： Spelina KR,Coates DP,Monk CR,Prys-Roberts C,Norley I,Turtle MJ

更新日期：1986-10-01 00:00:00