Analgesic effect in humans of subanaesthetic isoflurane concentrations evaluated by experimentally induced pain.

abstract：BACKGROUND:The significance of IgE antibodies to neuromuscular blocking agent (NMBA)-induced anaphylactic reactions during anaesthesia is unclear. We investigated the relevance of IgE to rocuronium using an in vitro technique. METHODS:Serum samples from 61 patients with anaphylactic reactions during anaesthesia were i...

journal_title：British journal of anaesthesia

authors： Aalberse RC,Kleine Budde I,Mulder M,Stapel SO,Paulij W,Leynadier F,Hollmann MW

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Owing to complexities of measuring dead space, ventilatory failure is difficult to quantify in critical care. A simple, novel index called ventilatory ratio (VR) can quantify ventilatory efficiency at the bedside. The study objectives were to evaluate physiological properties of VR and examine its clinical a...

journal_title：British journal of anaesthesia

authors： Sinha P,Singh S,Hardman JG,Bersten AD,Soni N,Australia and New Zealand Intensive Care Society Clinical Trials Group.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We explored whether a previously successful initiative to improve first-case on-time starts succeeded because (i) preoperative steps started earlier (but the process did not necessarily improve) or (ii) the process was brought into better control. METHODS:We analysed 35 months of data comprising 28 882 firs...

journal_title：British journal of anaesthesia

authors： Tiwari V,Ehrenfeld JM,Sandberg WS

更新日期：2018-11-01 00:00:00

abstract：:Sickle cell disease is a congenital haemoglobinopathy with a high incidence of perioperative complications. Traditional anaesthetic management, based largely on extrapolation from biochemical models, has emphasized avoidance of red cell sickling to prevent exacerbations of the disease. This historical review outlines ...

journal_title：British journal of anaesthesia

authors： Firth PG

更新日期：2005-09-01 00:00:00

abstract：:Patients with metastatic carcinoid tumours often undergo surgical procedures to reduce the tumour burden and associated debilitating symptoms. These procedures and anaesthesia can precipitate a life-threatening carcinoid crisis. To assess perioperative outcomes, we studied retrospectively the medical records of adult ...

journal_title：British journal of anaesthesia

authors： Kinney MA,Warner ME,Nagorney DM,Rubin J,Schroeder DR,Maxson PM,Warner MA

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Chronic treatment with renin-angiotensin system (RAS) antagonists frequently causes deleterious hypotension during anaesthesia. We compared the effects of angiotensin II receptor antagonists (ARA) and angiotensin-converting enzyme inhibitors (ACEI) on neurohormonal levels and haemodynamics during cardiopulmo...

journal_title：British journal of anaesthesia

authors： Oh YJ,Lee JH,Nam SB,Shim JK,Song JH,Kwak YL

更新日期：2006-12-01 00:00:00

abstract：:The determination of blood flow, i.e. cardiac output, is an integral part of haemodynamic monitoring. This is a review on noninvasive continuous cardiac output monitoring in perioperative and intensive care medicine. We present the underlying principles and validation data of the following technologies: thoracic elect...

journal_title：British journal of anaesthesia

authors： Saugel B,Cecconi M,Wagner JY,Reuter DA

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Age and diabetes mellitus have been identified as independent risk factors for cognitive decline after cardiac surgery with cardiopulmonary bypass (CPB). We tested the effects of CPB on cognitive function in aged and diabetic rats utilizing the Morris water maze (MWM). METHODS:Aged rats (26 months) were ran...

journal_title：British journal of anaesthesia

authors： de Lange F,Dieleman JM,Jungwirth B,Kalkman CJ

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:With the increasing prevalence of children who are overweight and with obesity, anaesthesiologists must determine the optimal dosing of medications given the altered pharmacokinetics and pharmacodynamics in this population. We therefore determined the single dose of dexmedetomidine that provided sufficient s...

journal_title：British journal of anaesthesia

authors： Wu B,Shan J,Zhou Q,Wang L

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:LMA CTrach (CT), a modified version of the intubating LMA Fastrach, allows continuous video-endoscopy of the tracheal intubation procedure. We tested the hypothesis that the CT is efficient for tracheal intubation of morbidly obese patients who are at risk of a difficult airway. METHODS:After Ethics' Commit...

journal_title：British journal of anaesthesia

authors： Dhonneur G,Ndoko SK,Yavchitz A,Foucrier A,Fessenmeyer C,Pollian C,Combes X,Tual L

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:In a series of ex vivo and in vivo studies we investigated the ability of repetitive ketamine administration to alter the metabolism and anaesthetic effect of propofol and the role of ketamine-mediated P-450 2B induction in rats. METHODS:Male Wistar rats were pretreated with 80 mg kg(-1) ketamine i.p. twice...

journal_title：British journal of anaesthesia

authors： Chan WH,Chen TL,Chen RM,Sun WZ,Ueng TH

更新日期：2006-09-01 00:00:00

abstract：:We describe a 25 mg intrathecal morphine overdose during a combined spinal-epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided. ...

journal_title：British journal of anaesthesia

authors： Cannesson M,Nargues N,Bryssine B,Debon R,Boselli E,Chassard D

更新日期：2002-12-01 00:00:00

abstract：:Intravenous dose-response relationships for dimethyl tubocurarine showed that vagal blockade only became appreciable (50-83%) at doses 8-16 times those sufficient for full neuromuscular paralysis in anaesthetized cats (0.0625 mg/kg) and rhesus monkeys (0.125 mg/kg); heart rate was unchanged. Sympathetic function was u...

journal_title：British journal of anaesthesia

authors： Hughes R,Chapple DJ

更新日期：1976-09-01 00:00:00

abstract：:Plasma concentrations of pancuronium were measured using a fluorimetric method in six patients with normal renal function and seven patients in chronic renal failure. A tow-compartment open model was used in the pharmacokinetic analysis of the data. With this model, the clearance of pancuronium was found to be reduce...

journal_title：British journal of anaesthesia

authors： McLeod K,Watson MJ,Rawlins MD

更新日期：1976-04-01 00:00:00

abstract：:Artery-to-muscle (A-M) onset time for five neuromuscular blocking agents was studied in 50 female patients under light endotracheal anaesthesia. Circulation to the right arm was occluded by a tourniquet and released 1 min after the injection i.v. into the left arm of a myoneural blocking drug. Muscle twitches were rec...

journal_title：British journal of anaesthesia

authors： Minsaas B,Stovner J

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:It was hypothesized that xenon would stabilize mean arterial pressure (MAP) in haemorrhagic shock, recovery, and volume resuscitation, because a higher MAP has been observed with xenon, when compared with isoflurane anaesthesia. The responses to haemorrhage and subsequent volume replacement were therefore co...

journal_title：British journal of anaesthesia

authors： Baumert JH,Hecker KE,Hein M,Reyle-Hahn SM,Horn NA,Rossaint R

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The debate on lung-protective ventilation strategies for surgical patients is ongoing. Evidence suggests that the use of low tidal volume VT improves clinical outcomes. However, the optimal levels of PEEP and recruitment manoeuvre (RM) strategies incorporated into low VT ventilation remain unclear. METHODS:...

journal_title：British journal of anaesthesia

authors： Deng QW,Tan WC,Zhao BC,Wen SH,Shen JT,Xu M

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Data on contributors to between-individual variability in overall tramadol clearance and O-demethyl tramadol (M1) formation in preterm neonates and young infants are limited. METHODS:A population pharmacokinetic analysis of tramadol and M1 was undertaken using non-linear mixed effects model. Covariate analy...

journal_title：British journal of anaesthesia

authors： Allegaert K,van den Anker JN,de Hoon JN,van Schaik RH,Debeer A,Tibboel D,Naulaers G,Anderson BJ

更新日期：2008-04-01 00:00:00

abstract：:Blood transfusion saves many lives but carries significant risk of injury. Currently, red blood cell (RBC) concentrates can be stored up to 42 days. Concerns have recently been raised about the safety and efficacy of transfusing stored RBCs. Refrigerated storage results in a 'storage lesion' that is reflected by metab...

journal_title：British journal of anaesthesia

authors： Cohen B,Matot I

更新日期：2013-12-01 00:00:00

abstract：:Gastric (GP) and lower oesophageal sphincter pressures (LOSP) were measured in non-pregnant female volunteers (group I) and pregnant women with (group III) or without (group II) heartburn. Patients in early pregnancy had greater gastric pressures than group I. Mean barrier pressure (LOSP-GP) was significantly decrease...

journal_title：British journal of anaesthesia

authors： Brock-Utne JG,Dow TG,Dimopoulos GE,Welman S,Downing JW,Moshal MG

更新日期：1981-04-01 00:00:00

abstract：:Intra-oral masses in neonates can seriously compromise the airway, potentially causing hypoxia and death if not recognized and managed appropriately. We report a case in which an intra-oral mass was diagnosed on antenatal ultrasound scan. Preparation for delivery involved a multidisciplinary team approach, with a stra...

journal_title：British journal of anaesthesia

authors： Skelton VA,Goodwin A

更新日期：1999-12-01 00:00:00

abstract：:This study has examined the effect of hydration on immediate recovery from anaesthesia in two groups of 15 patients undergoing therapeutic abortion. A standard anaesthetic technique was administered. Patients in group I received no preoperative fluid; those in group II received, before anaesthesia, 20 ml kg-1 of 4% gl...

journal_title：British journal of anaesthesia

authors： Ooi LG,Goldhill DR,Griffiths A,Smith C

更新日期：1992-06-01 00:00:00

abstract：:We have investigated the effect of dopamine and dopexamine on the isolated perfused rat kidney. After an equilibration period of 20 min and two control periods of 10 min, dopexamine 1.0, 2.5 or 4.0 micrograms kg-1 min-1 or dopamine 2.0 micrograms kg-1 min-1 were perfused for a further 40 min in random order. Renal blo...

journal_title：British journal of anaesthesia

authors： Kirchhoff K,Leuwer M,Thum P,Bornscheuer A,Piepenbrock S

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:The aim of this study is to test the hypothesis that a standard 30-min break in a routine 7.5 h period of work makes a difference in cognitive function. METHODS:In a double-blinded, cross-over trial 30 residents in anaesthesia were randomized to receive or not to receive a 30-min break between the assessmen...

journal_title：British journal of anaesthesia

authors： Coburn M,Henzler D,Baumert JH,Fimm B,Drüke B,Rossaint R

更新日期：2006-09-01 00:00:00

abstract：:Gas injection systems used in several techniques of ventilation cause increases in airway pressure and physiological changes which are frequently overlooked. The momentum flux theory describes such phenomena most appropriately. We have defined and measured the characteristics of such increases in airway pressure, usin...

journal_title：British journal of anaesthesia

authors： Isabey D,Boussignac G,Harf A

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The objective of the present study was to investigate the effects of increasing doses of norepinephrine (NE) with or without arginine-vasopressin (AVP) on intestinal oxygen supply and jejunal mucosal tissue oxygen tension in an acute endotoxic pig model. METHODS:In this prospective, randomized, experimental...

journal_title：British journal of anaesthesia

authors： Maier S,Hasibeder W,Pajk W,Hengl C,Ulmer H,Hausdorfer H,Wurzinger B,Knotzer H

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Transitions into and out of the anaesthetised state exhibit resistance to state transitions known as neural inertia. As a consequence, emergence from anaesthesia occurs at a consistently lower anaesthetic concentration than induction. Motivated by stochastic switching between discrete activity patterns obser...

journal_title：British journal of anaesthesia

authors： Proekt A,Hudson AE

更新日期：2018-07-01 00:00:00

abstract：:Thirty hypertensive patients scheduled for cholecystectomy or hernia repair under general anaesthesia with thiopentone-fentanyl-nitrous oxide-pancuronium were divided into two groups of 15. One group received metoprolol tablets 200 mg in a slow release form, once daily for at least 2 weeks including the morning of sur...

journal_title：British journal of anaesthesia

authors： Magnusson J,Thulin T,Werner O,Järhult J,Thomson D

更新日期：1986-03-01 00:00:00

abstract：:Falls are a known public health problem, and there is increasing recognition of the importance of perioperative falls for risk prediction and quality assessment. Our objective was to review existing literature regarding the occurrence, injuries, and risk factors of preoperative and postoperative falls. A systematized ...

journal_title：British journal of anaesthesia

authors： Kronzer VL,Wildes TM,Stark SL,Avidan MS

更新日期：2016-12-01 00:00:00

abstract：:To assess the effect of sevoflurane anaesthesia on hepatocellular integrity, we measured plasma concentrations of glutathione S-transferase (GST) before anaesthesia and 1, 3, 6 and 24 h after the end of anaesthesia in 41 healthy, Japanese patients undergoing elective, body surface surgery. Sevoflurane (approximately 1...

journal_title：British journal of anaesthesia

authors： Ray DC,Bomont R,Mizushima A,Kugimiya T,Forbes Howie A,Beckett GJ

更新日期：1996-09-01 00:00:00