Perianaesthetic risks and outcomes of abdominal surgery for metastatic carcinoid tumours.

Abstract:

:Patients with metastatic carcinoid tumours often undergo surgical procedures to reduce the tumour burden and associated debilitating symptoms. These procedures and anaesthesia can precipitate a life-threatening carcinoid crisis. To assess perioperative outcomes, we studied retrospectively the medical records of adult patients from 1983 to 1996 who underwent abdominal surgery for metastatic carcinoid tumours. Preoperative risk factors, intraoperative complications and complications occurring in the 30 days after surgery were recorded. Perioperative complications or death occurred in 15 of 119 patients (12.6%, exact confidence interval 7.2-19.9). None of the 45 patients who received octreotide intraoperatively experienced intraoperative complications compared with eight of the 73 patients (11.0%) who did not receive octreotide (P=0.023). The presence of carcinoid heart disease and high urinary output of 5-hydroxyindoleacetic acid preoperatively were statistically significant risk factors for perioperative complications.

journal_name

Br J Anaesth

authors

Kinney MA,Warner ME,Nagorney DM,Rubin J,Schroeder DR,Maxson PM,Warner MA

doi

10.1093/bja/87.3.447

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

447-52

issue

3

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)36643-6

journal_volume

87

pub_type

杂志文章
  • Influence of cuff volume on oropharyngeal leak pressure and fibreoptic position with the laryngeal mask airway.

    abstract::We studied the size 4 laryngeal mask airway (LMA) to test the hypothesis that oropharyngeal leak pressure and fibreoptic position improves with increasing cuff volume. After LMA insertion, 50 anaesthetized adult patients had the cuff inflated in 5-ml increments to 40 ml. Oropharyngeal leak pressure was optimal at 15 m...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/81.2.186

    authors: Keller C,Pühringer F,Brimacombe JR

    更新日期:1998-08-01 00:00:00

  • The skeletal muscle response to edrophonium during neuromuscular blockade by tubocurarine in anaesthetized man.

    abstract::Tetanic contractions of the adductor pollicis muscle in man were evaluated continuously after the administration of tubocurarine 0.2 mg/kg and during reversal by edrophonium 0.1 mg/kg. Single twitch contractions of the adductor pollicis were measured simultaneously. The response of tetanic and single twitch contractio...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/47.10.1087

    authors: Sugai N,Payne JP

    更新日期:1975-10-01 00:00:00

  • Effect of segmental extradural analgesia on placental blood flow during normal labour.

    abstract::Placental blood flow was measured during the first stage of normal labour using a xenon-133 clearance technique before and after segmental extradural analgesia. Analgesia was produced with 0.5% plain bupivacaine in eight patients and with 0.5% bupivacaine--adrenaline in 10 patients. Segmental extradural analgesia with...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/50.6.563

    authors: Jouppila R,Jouppila P,Hollmén A,Kuikka J

    更新日期:1978-06-01 00:00:00

  • Training course in local anaesthesia of the airway and fibreoptic intubation using course delegates as subjects.

    abstract:BACKGROUND:We describe a practical method of training anaesthetists in the technique of awake fibreoptic intubation. This is performed on a training course using the delegates as subjects. METHODS:The first 15 subjects underwent cardiovascular monitoring during airway fibreoptic endoscopy performed by other course mem...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aef226

    authors: Patil V,Barker GL,Harwood RJ,Woodall NM

    更新日期:2002-10-01 00:00:00

  • Efficacy of palonosetron for the prevention of postoperative nausea and vomiting: a randomized, double-blinded, placebo-controlled trial.

    abstract:BACKGROUND:The aim of this study was to evaluate the efficacy of palonosetron, the latest 5-HT3 receptor antagonist, for the prevention of postoperative nausea and vomiting (PONV) during the first 72 h after operation. METHODS:In this randomized, double-blinded, placebo-controlled study, 204 healthy inpatients who wer...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aet340

    authors: Chun HR,Jeon IS,Park SY,Lee SJ,Kang SH,Kim SI

    更新日期:2014-03-01 00:00:00

  • Anaesthesia and intensive care management of face transplantation.

    abstract::The face-grafting techniques are innovative and highly complex, requiring well-defined organization of all the teams involved. Subsequent to the first report in France in 2005, there have been 17 facial allograft transplantations performed worldwide. We describe anaesthesia and postoperative management, and the proble...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aet159

    authors: Sedaghati-nia A,Gilton A,Liger C,Binhas M,Cook F,Ait-Mammar B,Scherrer E,Hivelin M,Lantieri L,Marty J,Plaud B

    更新日期:2013-10-01 00:00:00

  • One-lung ventilation induces hyperperfusion and alveolar damage in the ventilated lung: an experimental study.

    abstract:BACKGROUND:One-lung ventilation (OLV) increases mechanical stress in the lung and affects ventilation and perfusion (V, Q). There are no data on the effects of OLV on postoperative V/Q matching. Thus, this controlled study evaluates the influence of OLV on V/Q distribution in a pig model using a gamma camera technique ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aen021

    authors: Kozian A,Schilling T,Fredén F,Maripuu E,Röcken C,Strang C,Hachenberg T,Hedenstierna G

    更新日期:2008-04-01 00:00:00

  • Oxygen supplementation during electroconvulsive therapy.

    abstract::The effects of ventilation with 30% and 100% oxygen were investigated on the circulatory and electrocardiographic response to electroconvulsive therapy (ECT) in 12 patients during 40 treatments. Administration of 30% oxygen resulted in a 25% decrease in seizure duration compared with 100% oxygen (P less than 0.0125). ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/61.5.593

    authors: Räsänen J,Martin DJ,Downs JB,Hodges MR

    更新日期:1988-11-01 00:00:00

  • Ability of stroke volume variation measured by oesophageal Doppler monitoring to predict fluid responsiveness during surgery.

    abstract:BACKGROUND:The objective of this study was to test whether non-invasive assessment of respiratory stroke volume variation (ΔrespSV) by oesophageal Doppler monitoring (ODM) can predict fluid responsiveness during surgery in a mixed population. The predictive value of ΔrespSV was evaluated using a grey zone approach. ME...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aes301

    authors: Guinot PG,de Broca B,Abou Arab O,Diouf M,Badoux L,Bernard E,Lorne E,Dupont H

    更新日期:2013-01-01 00:00:00

  • Effect of doxapram on the rate of recovery from atracurium and vecuronium neuromuscular block.

    abstract::We have studied the effect of doxapram on the rates of spontaneous and neostigmine-induced recovery from neuromuscular block with atracurium and vecuronium, by measurement of the time to recovery of T1 (first twitch in the train-of-four) from 25 to 75% of control (recovery index, RI). After each neuromuscular blocking...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/68.5.527

    authors: Cooper R,McCarthy G,Mirakhur RK,Maddineni VR

    更新日期:1992-05-01 00:00:00

  • Comparison between glycopyrrolate and atropine in a mixture with neostigmine for reversal of neuromuscular blockade. Studies in patients following open heart surgery.

    abstract::Atropine and glycopyrrolate were compared in a mixture with neostigmine for reversal of neuromuscular blockade in patients undergoing open heart surgery. In patients not receiving beta-blocking drugs, glycopyrrolate was shown to possess advantages over atropine in terms of a lower initial increase in heart rate, bette...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/57.2.184

    authors: Salem MG,Richardson JC,Meadows GA,Lamplugh G,Lai KM

    更新日期:1985-02-01 00:00:00

  • Minimum local analgesic concentration of extradural bupivacaine increases with progression of labour.

    abstract::We have used the technique of double-blind sequential allocation to quantify the minimum local analgesic concentration (MLAC) of extradural bupivacaine for women in early (median cervical dilatation 2 cm) and late (median cervical dilatation 5 cm) labour. The first bolus was 20 ml of the bupivacaine test solution. The...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/80.1.11

    authors: Capogna G,Celleno D,Lyons G,Columb M,Fusco P

    更新日期:1998-01-01 00:00:00

  • Experience with spinal analgesia in a British obstetric unit.

    abstract::A series of 443 spinal anaesthetics is described. The procedures included operative vaginal delivery, removal of retained placenta and a miscellaneous group common to most obstetric units. Failure to provide effective relief of pain occurred in 5.2% of patients. There was one potentially serious complication, but with...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/51.6.531

    authors: Crawford JS

    更新日期:1979-06-01 00:00:00

  • Impact of phenylephrine administration on cerebral tissue oxygen saturation and blood volume is modulated by carbon dioxide in anaesthetized patients.

    abstract:BACKGROUND:Multiple studies have shown that cerebral tissue oxygen saturation (Sct(O(2))) is decreased after phenylephrine treatment. We hypothesized that the negative impact of phenylephrine administration on Sct(O(2)) is affected by arterial blood carbon dioxide partial pressure (Pa(CO(2))) because CO(2) is a powerfu...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/aes023

    authors: Meng L,Gelb AW,Alexander BS,Cerussi AE,Tromberg BJ,Yu Z,Mantulin WW

    更新日期:2012-05-01 00:00:00

  • Effect of ivabradine on major adverse cardiovascular events and mortality in critically ill patients: a systematic review and meta-analyses of randomised controlled trials with trial sequential analyses.

    abstract:BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.bja.2020.01.027

    authors: Chen A,Elia N,Dunaiceva J,Rudiger A,Walder B,Bollen Pinto B

    更新日期:2020-06-01 00:00:00

  • Effect of pretreatment with oral pyridostigmine on subsequent activity of alcuronium in non-anaesthetized subjects.

    abstract::We have studied the effects of alcuronium in 10 healthy, non-anaesthetized volunteers after they had been taking oral pyridostigmine 30 mg 8 hourly. The responses of adductor pollicis were recorded using an isolated forearm procedure (IFP) during onset and recovery of neuromuscular block produced by 1.5 mg of relaxant...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/66.3.365

    authors: Turner GA,Williams JD,Baker DJ

    更新日期:1991-03-01 00:00:00

  • Assessment of changes in lactate concentration with intravascular microdialysis during high-risk cardiac surgery using the trend interchangeability method.

    abstract:Background:Blood lactate is a strong predictor of mortality, and repeated blood lactate assays are recommended during surgery in high-risk patients. We hypothesized that the use of intravascular microdialysis incorporated in a central venous catheter would be interchangeable with the reference blood gas technique to mo...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aex338

    authors: Gouëzel C,Lorne E,Bonnet V,Fradin S,Saplacan V,Gérard JL,Hanouz JL,Fellahi JL,Fischer MO,FHT (French Hemodynamic Team).

    更新日期:2017-12-01 00:00:00

  • Immediate extubation and epidural analgesia allow safe management in a high-dependency unit after two-stage oesophagectomy. Results of eight years of experience in a specialized upper gastrointestinal unit in a district general hospital.

    abstract:BACKGROUND:The perioperative management of two-stage oesophagectomy has not been standardized and the prevailing practice regarding the timing of extubation after the procedure varies. This audit has evaluated the outcome, in particular the respiratory morbidity and mortality, after immediate extubation in patients who...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeg091

    authors: Chandrashekar MV,Irving M,Wayman J,Raimes SA,Linsley A

    更新日期:2003-04-01 00:00:00

  • Safe use of remifentanil in a patient treated with the monoamine oxidase inhibitor phenelzine.

    abstract::We report the safe use of remifentanil as part of the anaesthetic technique in a patient undergoing major head and neck surgery who was being treated for depressive illness with the non-specific monoamine oxidase inhibitor (MAOI) phenelzine. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.bja.a013453

    authors: Ure DS,Gillies MA,James KS

    更新日期:2000-03-01 00:00:00

  • Binding of tubocurarine, fazadinium, pancuronium and Org NC 45 to serum proteins in normal man and in patients with cirrhosis.

    abstract::The protein binding of four non-depolarizing neuromuscular blocking drugs-tubocurarine, fazadinium, pancuronium and Org NC45-was measured, in serum from normal patients and from patients with cirrhosis of the liver, by an ultracentrifugation method. The fraction bound to serum protein in normal patients was 56% for tu...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/54.5.513

    authors: Duvaldestin P,Henzel D

    更新日期:1982-05-01 00:00:00

  • Comparison of hyperbaric and plain articaine in spinal anaesthesia for open inguinal hernia repair.

    abstract:BACKGROUND:Fast onset and short duration are prominent properties of the amide-type local anaesthetic articaine. Similar to bupivacaine, a hyperbaric solution of articaine may produce faster onset and shorter duration of spinal anaesthesia than a plain solution. METHODS:Patients undergoing open inguinal hernia repair ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aen294

    authors: Bachmann M,Pere P,Kairaluoma P,Rosenberg PH,Kallio H

    更新日期:2008-12-01 00:00:00

  • Effect of volatile anaesthetics on cell survival as measured by colony forming ability.

    abstract::Chinese hamster fibroblast cells in stirred suspension cultures were exposed to volatile anaesthetic agents for 3 hr or for 24 hr. Cell viability was measured as colony forming ability and was found to be reduced, in a dose related manner, by halothane, chloroform, methoxyflurane, trichloroetheylene and diethyl ether....

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/47.8.831

    authors: Sturrock JE

    更新日期:1975-08-01 00:00:00

  • Hand-hygiene practices in the operating theatre: an observational study.

    abstract:BACKGROUND:The current prevalence of healthcare-associated infections (HCAIs) is a major public health concern. Patient contact in the operating theatre (OT) can contribute to HCAI via microbial contamination. The application of hand hygiene is effective in reducing infection rates. Limited data are available on adhere...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer162

    authors: Krediet AC,Kalkman CJ,Bonten MJ,Gigengack AC,Barach P

    更新日期:2011-10-01 00:00:00

  • Determination of ED95 of a single-bolus dose of dexmedetomidine for adequate sedation in children and adolescents with and without obesity.

    abstract:BACKGROUND:With the increasing prevalence of children who are overweight and with obesity, anaesthesiologists must determine the optimal dosing of medications given the altered pharmacokinetics and pharmacodynamics in this population. We therefore determined the single dose of dexmedetomidine that provided sufficient s...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2020.11.037

    authors: Wu B,Shan J,Zhou Q,Wang L

    更新日期:2021-01-22 00:00:00

  • Local anaesthetic sensitivities of cloned HERG channels from human heart: comparison with HERG/MiRP1 and HERG/MiRP1 T8A.

    abstract:BACKGROUND:Myocardial potassium channels are complexes formed by different subunits. The subunit composition may influence the cardiotoxic action of local anaesthetics. The effects of amide local anaesthetics on HERG channels co-expressed with the putative subunit MiRP1 have not been established. It is also unclear if ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeh026

    authors: Friederich P,Solth A,Schillemeit S,Isbrandt D

    更新日期:2004-01-01 00:00:00

  • Impact of metabolic syndrome in surgical patients: should we bother?

    abstract::Clinicians inevitably encounter patients who meet the diagnostic criteria for the metabolic syndrome (MetS); these criteria include central obesity, hypertension, atherogenic dyslipidaemia, and hyperglycaemia. Regardless of the variations in its definition, MetS may be associated with adverse outcomes in patients unde...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aev199

    authors: Tzimas P,Petrou A,Laou E,Milionis H,Mikhailidis DP,Papadopoulos G

    更新日期:2015-08-01 00:00:00

  • Performance of proportional and continuous nitric oxide delivery systems during pressure- and volume-controlled ventilation.

    abstract::We have evaluated the effect of delivering nitric oxide using a continuous flow system (CFS) or two commercially available proportional gas injection systems (PGIS), Nodomo (Dräger, Lübeck, Germany) and Pulmonox-Mini (Messer Griesheim Austria, Gumpoldskirchen, Austria) on measured and simulated concentrations of nitri...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/81.4.544

    authors: Hiesmayr MJ,Neugebauer T,Lassnigg A,Steltzer H,Haider W,Gilly H

    更新日期:1998-10-01 00:00:00

  • Morbidity after day-case gynaecological surgery. Comparison of enflurane with halothane.

    abstract::In 105 patients undergoing day-case surgery recovery of consciousness was significantly faster after enfluane compared with halothane anaesthesia. There was no difference in postoperative morbidity between the two anaesthetic groups. ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/51.12.1143

    authors: Stanford BJ,Plantevin OM,Gilbert JR

    更新日期:1979-12-01 00:00:00

  • In vivo determination of concentration-effect curves of local anaesthetics in man.

    abstract::In clinical use, the concentrations of local anaesthetics at the site of action are unknown. With the method described here, concentrations of local anaesthetics can be predetermined and kept constant at the site of action. In six volunteers, a blister was raised on the ventral surface of the forearm. After removal of...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/70.5.552

    authors: Wiesemes R,Klement W,Novotny GE,Lipfert P

    更新日期:1993-05-01 00:00:00

  • Influence of the site of measurement on the ability of plethysmographic variability index to predict fluid responsiveness.

    abstract:BACKGROUND:Plethysmographic variability index (PVI) is an accurate predictor of fluid responsiveness in mechanically ventilated patients. However, the site of measurement of the plethysmographic waveform impacts its morphology and its respiratory variation. The goal of this study was to investigate the ability of PVI t...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer165

    authors: Desgranges FP,Desebbe O,Ghazouani A,Gilbert K,Keller G,Chiari P,Robin J,Bastien O,Lehot JJ,Cannesson M

    更新日期:2011-09-01 00:00:00