Binding of tubocurarine, fazadinium, pancuronium and Org NC 45 to serum proteins in normal man and in patients with cirrhosis.

abstract：:Forty-five patients undergoing circumcision were allocated randomly to one of three study groups to compare topical analgesia with dorsal nerve block using the midline or lateral approach. Pain scores, side effects and analgesic requirements were recorded after surgery. Patients who received topical analgesia required...

journal_title：British journal of anaesthesia

authors： Chambers FA,Lee J,Smith J,Casey W

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:There are regional differences in the effects of anaesthetics agents and perioperative stimuli on the EEG. We studied the topography of the EEG during induction of anaesthesia and intubation in patients receiving thiopental and fentanyl to document regional electrical brain activity. METHODS:EEG was recorde...

journal_title：British journal of anaesthesia

authors： Rundshagen I,Schröder T,Prichep LS,John ER,Kox WJ

更新日期：2004-01-01 00:00:00

abstract：:We have studied the cardiovascular effects of equipotent concentrations of halothane or isoflurane, with or without 50% nitrous oxide in oxygen, in 80 patients, aged 60 yr or more, during 20 min of stable equipotent anaesthesia. Non-invasive measurement techniques were used, with suprasternal Doppler ultrasonography f...

journal_title：British journal of anaesthesia

authors： McKinney MS,Fee JP

更新日期：1998-02-01 00:00:00

abstract：:The effects of laudanosine, a metabolite of atracurium, on the behaviour of conscious mice, rats and dogs, and on cardiovascular function in conscious and anaesthetized dogs have been evaluated: EEG studies were performed in anaesthetized dogs. In mice and rats, i.v. bolus doses of laudanosine 10-20 mg kg-1, caused co...

journal_title：British journal of anaesthesia

authors： Chapple DJ,Miller AA,Ward JB,Wheatley PL

更新日期：1987-02-01 00:00:00

abstract：:Blood flow to functionally different vascular beds was examined during a sodium nitroprusside infusion in 10 dogs anaesthetized with halothane (1 MAC) in oxygen. Blood flows were measured in the ascending aorta, and the coeliac, superior mesenteric, renal and iliac arteries. In two dogs, regional vascular impedance an...

journal_title：British journal of anaesthesia

authors： Bagshaw RJ,Cox RH,Campbell KB

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Data on contributors to between-individual variability in overall tramadol clearance and O-demethyl tramadol (M1) formation in preterm neonates and young infants are limited. METHODS:A population pharmacokinetic analysis of tramadol and M1 was undertaken using non-linear mixed effects model. Covariate analy...

journal_title：British journal of anaesthesia

authors： Allegaert K,van den Anker JN,de Hoon JN,van Schaik RH,Debeer A,Tibboel D,Naulaers G,Anderson BJ

更新日期：2008-04-01 00:00:00

abstract：:We have examined the effects of the highly selective alpha 2-adrenoceptor agonist, dexmedetomidine, on noradrenaline release and cell firing in isolated, superfused slices of rat locus coeruleus. Dexmedetomidine decreased both noradrenaline release and cell firing rate in a concentration-dependent fashion, with an EC5...

journal_title：British journal of anaesthesia

authors： Jorm CM,Stamford JA

更新日期：1993-09-01 00:00:00

abstract：:Maternal haemorrhage is the leading cause of preventable maternal death worldwide and encompasses antepartum, intrapartum, and postpartum bleeding. This review highlights factors that predispose to severe bleeding, its management, and the most recent treatment and guidelines. Advances in obstetric care have provided p...

journal_title：British journal of anaesthesia

authors： Walfish M,Neuman A,Wlody D

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:In regional anaesthesia, there is a risk of direct nerve injury. The purpose of this study was to determine whether the diameter of the applied needle is associated with the magnitude of nerve injury after needle nerve perforation. METHODS:In five anaesthetized pigs, the brachial plexus were exposed bilater...

journal_title：British journal of anaesthesia

authors： Steinfeldt T,Nimphius W,Werner T,Vassiliou T,Kill C,Karakas E,Wulf H,Graf J

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The therapeutic potential of cardiac μ-opioid receptors in ischaemia-reperfusion (I/R) injury during opioid-modulating diseases, such as heart failure, is unknown. We aimed to explore the changes of cardiac μ-opioid receptor expression during heart failure, and its role in opioid-induced cardioprotection. M...

journal_title：British journal of anaesthesia

authors： He SF,Jin SY,Yang W,Pan YL,Huang J,Zhang SJ,Zhang L,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Moderate to deep sedation has been recommended during endoscopic submucosal dissection (ESD). However, it is often accompanied by adverse events such as respiratory depression or aspiration pneumonia. This study investigated the respiratory complications and ESD outcomes of two sedation protocols: moderate s...

journal_title：British journal of anaesthesia

authors： Yoo YC,Park CH,Shin S,Park Y,Lee SK,Min KT

更新日期：2015-07-01 00:00:00

abstract：:In a prospective randomized multi-centre study, the mortality following internal fixation surgery for fracture of the upper femur was investigated in 538 elderly patients allocated to receive subarachnoid blockade or general (narcotic-relaxant) anaesthesia. The 28-day mortality was 6.6% with subarachnoid, and 5.9% wit...

journal_title：British journal of anaesthesia

authors： Davis FM,Woolner DF,Frampton C,Wilkinson A,Grant A,Harrison RT,Roberts MT,Thadaka R

更新日期：1987-09-01 00:00:00

abstract：:We report the successful preoperative control and anaesthetic management of severe hypertension in a 7-month-old baby with nephroblastoma and increased renin activity. The strategy for selection of appropriate antihypertensive pharmacological agents and the anaesthetic implications and management of the condition are ...

journal_title：British journal of anaesthesia

authors： Charlton GA,Sedgwick J,Sutton DN

更新日期：1992-08-01 00:00:00

abstract：:We have studied the effects of flow and dobutamine on systemic haemodynamic variables, oxygen delivery (DO2) and oxygen consumption (VO2) in 20 patients during cardiopulmonary bypass (CPB) with mild hypothermia (34 degrees C). In a subgroup of seven patients, we also studied the effects on gastric microcirculatory blo...

journal_title：British journal of anaesthesia

authors： Karzai W,Lötte A,Günnicker M,Vorgrimler-Karzai UM,Priebe HJ

更新日期：1996-01-01 00:00:00

abstract：:The analgesic effect of subanaesthetic concentrations of ether, trichloroethylene, methoxyflurane and halothane has been investigated previously using either clinical assessment or pain threshold measurements, but with conflicting results. The purpose of the present study was to evaluate the analgesic effect of isoflu...

journal_title：British journal of anaesthesia

authors： Petersen-Felix S,Arendt-Nielsen L,Bak P,Roth D,Fischer M,Bjerring P,Zbinden AM

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Arousal after sevoflurane anaesthesia has been detectable by monitoring changes in skin conductance (SC) with similar accuracy as monitoring Bispectral Index (BIS). As SC monitoring detects changes in sympathetic tone, the measurements might be confounded by the sympatholytic properties of propofol, a compon...

journal_title：British journal of anaesthesia

authors： Ledowski T,Bromilow J,Paech MJ,Storm H,Hacking R,Schug SA

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Perioperative warming is recommended for surgery under anaesthesia, however its role during Caesarean delivery remains unclear. This meta-analysis aimed to determine the efficacy of active warming on outcomes after elective Caesarean delivery. METHODS:We searched databases for randomized controlled trials u...

journal_title：British journal of anaesthesia

authors： Sultan P,Habib AS,Cho Y,Carvalho B

更新日期：2015-10-01 00:00:00

abstract：:This study was designed to observe the effects of i.v. fluid infusion on uterine activity during normal labour in women receiving an extradural block. Thirty-four women in spontaneous labour at term gestation were allocated randomly and prospectively to one of three i.v. pre-extradural fluid load groups: group A, no f...

journal_title：British journal of anaesthesia

authors： Cheek TG,Samuels P,Miller F,Tobin M,Gutsche BB

更新日期：1996-11-01 00:00:00

abstract：:NHS Blood and Transplant (NHSBT) was established in 2005 as a Special Health Authority when the National Blood Authority and UK Transplant merged. This helped to bring tissue banking and organ transplantation services under one umbrella organization. This merger means that ~!95% of all deceased donors (whether tissue,...

journal_title：British journal of anaesthesia

authors： Gaum L,Reynolds I,Jones MN,Clarkson AJ,Gillan HL,Kaye SB

更新日期：2012-01-01 00:00:00

abstract：:Falls are a known public health problem, and there is increasing recognition of the importance of perioperative falls for risk prediction and quality assessment. Our objective was to review existing literature regarding the occurrence, injuries, and risk factors of preoperative and postoperative falls. A systematized ...

journal_title：British journal of anaesthesia

authors： Kronzer VL,Wildes TM,Stark SL,Avidan MS

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Arterial cannulation is a common anaesthetic procedure that can be challenging and time-consuming in small children. By visualizing the position of the radial artery, near-infrared vascular imaging systems (NIRVISs) might be of assistance in arterial cannulation. The present study evaluates the effectiveness...

journal_title：British journal of anaesthesia

authors： Cuper NJ,de Graaff JC,Hartman BJ,Verdaasdonk RM,Kalkman CJ

更新日期：2012-09-01 00:00:00

abstract：:We have undertaken a prospective, randomized study to determine the incidence of postoperative nausea and vomiting during intensive care stay after cardiac surgery, and to study the effect of addition of droperidol to an infusion of morphine used for postoperative analgesia. Data from 398 patients were examined. The u...

journal_title：British journal of anaesthesia

authors： Grebenik CR,Allman C

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The Laryngeal Tube (LT) performs similarly to the classic laryngeal mask airway during controlled ventilation but with an improved airway seal. We compared the laryngeal tube with the ProSeal laryngeal mask airway (PLMA) throughout anaesthesia. METHODS:Thirty-two patients were studied using a randomized cro...

journal_title：British journal of anaesthesia

authors： Cook TM,McKinstry C,Hardy R,Twigg S

更新日期：2003-11-01 00:00:00

abstract：:Human error poses significant risk for hospitalized patients causing an estimated 100,000 to 400,000 deaths in the USA annually. Medication errors contribute, with error occurring in 5.3% of medication administrations during surgery. In this study 70.3% of medication errors were deemed preventable. Given the paucity o...

journal_title：British journal of anaesthesia

authors： Wahr JA,Abernathy JH 3rd,Lazarra EH,Keebler JR,Wall MH,Lynch I,Wolfe R,Cooper RL

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The usefulness of the PFA-100 in assessing the risk of bleeding in non-cardiac surgery is not clear. This study aims to examine this by correlating preoperative PFA-100 measurement with perioperative bleeding in patients receiving cyclooxygenase (COX) inhibitors. METHODS:PFA-100 with adenosine-5'-diphosphat...

journal_title：British journal of anaesthesia

authors： Ng KF,Lawmin JC,Tsang SF,Tang WM,Chiu KY

更新日期：2009-06-01 00:00:00

abstract：:The rapid detection and evaluation of patients presenting with perioperative neurological dysfunction is of great clinical relevance. Biomarkers have been defined as biological molecules that can be used as an indicator of new onset or progression of a biological process or effect of treatment. Biomarkers have become ...

journal_title：British journal of anaesthesia

authors： Cata JP,Abdelmalak B,Farag E

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Ketamine is used as an anaesthetic agent for short surgical procedures, and as a sedative and analgesic in intensive care patients. Intensive care patients with brain or spinal cord injury may have physiological changes that could alter the pharmacokinetics of ketamine. The pharmacokinetics of ketamine have ...

journal_title：British journal of anaesthesia

authors： Hijazi Y,Bodonian C,Bolon M,Salord F,Boulieu R

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Plethysmographic variability index (PVI) is an accurate predictor of fluid responsiveness in mechanically ventilated patients. However, the site of measurement of the plethysmographic waveform impacts its morphology and its respiratory variation. The goal of this study was to investigate the ability of PVI t...

journal_title：British journal of anaesthesia

authors： Desgranges FP,Desebbe O,Ghazouani A,Gilbert K,Keller G,Chiari P,Robin J,Bastien O,Lehot JJ,Cannesson M

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The current prevalence of healthcare-associated infections (HCAIs) is a major public health concern. Patient contact in the operating theatre (OT) can contribute to HCAI via microbial contamination. The application of hand hygiene is effective in reducing infection rates. Limited data are available on adhere...

journal_title：British journal of anaesthesia

authors： Krediet AC,Kalkman CJ,Bonten MJ,Gigengack AC,Barach P

更新日期：2011-10-01 00:00:00

abstract：Background:The influence of different head and neck positions on the effectiveness of ventilation with the air-Q® self-pressurizing airway remains unevaluated. This study aimed to evaluate the influence of different head and neck positions on ventilation with the air-Q® SP airway. Methods:In this prospective, randomiz...

journal_title：British journal of anaesthesia

authors： Kim HJ,Lee K,Bai S,Kim MH,Oh E,Yoo YC

更新日期：2017-03-01 00:00:00