Changes in cortical electrical activity during induction of anaesthesia with thiopental/fentanyl and tracheal intubation: a quantitative electroencephalographic analysis.

abstract：BACKGROUND:Magnesium is a calcium and an NMDA-receptor antagonist and can modify important mechanisms of nociception. We evaluated the co-analgesic effect of magnesium in the postoperative setting after on-pump cardiac surgery. METHODS:Forty patients randomly received either magnesium gluconate as an i.v. bolus of 0.2...

journal_title：British journal of anaesthesia

authors： Steinlechner B,Dworschak M,Birkenberg B,Grubhofer G,Weigl M,Schiferer A,Lang T,Rajek A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:To determine the pharmacokinetics (PK) of a new i.v. formulation of paracetamol (Perfalgan) in children ≤15 yr of age. METHODS:After obtaining written informed consent, children under 16 yr of age were recruited to this study. Blood samples were obtained at 0, 15, 30 min, 1, 2, 4, 6, and 8 h after administr...

journal_title：British journal of anaesthesia

authors： Mohammed BS,Engelhardt T,Cameron GA,Cameron L,Hawksworth GM,Hawwa AF,McElnay J,Helms PJ,McLay JS

更新日期：2012-05-01 00:00:00

abstract：:The effects of the i.v. infusion of insulin, 70 mu. kg-1h-1 for the first 60 min and 35 mu. kg-1h-1 subsequently, on the metabolic and endocrine responses to gynaecological surgery were investigated. In comparison with a control group of patients, the insulin infusion caused a marked decrease in circulating glucose, n...

journal_title：British journal of anaesthesia

authors： Hall GM,Walsh ES,Paterson JL,Mashiter K

更新日期：1983-10-01 00:00:00

abstract：:Units for the investigation of susceptibility to malignant hyperthermia (MH) were set up in Denmark in 1977 and in Sweden in 1981. Two hundred and ten patients from 76 families have been investigated. The diagnosis of MH susceptibility (MHS) was made by in vitro exposure of muscle from vastus medialis to halothane and...

journal_title：British journal of anaesthesia

authors： Ording H,Ranklev E,Fletcher R

更新日期：1984-11-01 00:00:00

abstract：:Sickle cell disease is a congenital haemoglobinopathy with a high incidence of perioperative complications. Traditional anaesthetic management, based largely on extrapolation from biochemical models, has emphasized avoidance of red cell sickling to prevent exacerbations of the disease. This historical review outlines ...

journal_title：British journal of anaesthesia

authors： Firth PG

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:We investigated the effects of spinal and general anaesthesia and surgical tourniquet on acute pain and early recovery after total knee arthroplasty (TKA). METHODS:Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without...

journal_title：British journal of anaesthesia

authors： Palanne R,Rantasalo M,Vakkuri A,Madanat R,Olkkola KT,Lahtinen K,Reponen E,Linko R,Vahlberg T,Skants N

更新日期：2020-11-01 00:00:00

abstract：Background:Identification of statistically reliable outcomes for comparison among anaesthetists is challenging. Time-weighted intraoperative mean arterial pressure <65 mm Hg (AUC 65 ) is associated with increased odds for myocardial damage. We explored retrospectively whether such hypotension before incision was statis...

journal_title：British journal of anaesthesia

authors： Epstein RH,Dexter F,Schwenk ES

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Handover of anaesthesia patient care during surgery is common; however, its association with patient outcome is unclear. This systematic review aimed to assess the impact of anaesthesia handover during surgery on patient outcome. METHODS:All prospective and retrospective clinical studies specifically invest...

journal_title：British journal of anaesthesia

authors： Boet S,Djokhdem H,Leir SA,Théberge I,Mansour F,Etherington N

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The cuff pressures may be different in oesophageal and tracheal intubations. We conducted a study to evaluate if cuff pressures of endotracheal tubes (ETTs) could provide information to distinguish tracheal or oesophageal intubations in a pig trachea-oesophagus model. METHODS:In each preparation of pig trac...

journal_title：British journal of anaesthesia

authors： Lin HJ,Chen KT,Foo NP,Hsu CC,Guo HR

更新日期：2007-11-01 00:00:00

abstract：:By analysing the EEG, reticular multi-unit activity and behavioural changes, we have classified general anaesthetics into three groups: central nervous system (CNS) depressant, CNS excitant and epileptogenic agents. Changes in CNS neural activity are associated with alteration in transmitter release. We have attempted...

journal_title：British journal of anaesthesia

authors： Shichino T,Murakawa M,Adachi T,Arai T,Miyazaki Y,Mori K

更新日期：1998-03-01 00:00:00

abstract：:The experimental effort that has been expended in investigating the effects of general anaesthetics on LGICs has been enormous over the past decade. Members of all three LGIC superfamilies have been examined using electrophysiological techniques. Anaesthetics that have been examined include volatile anaesthetics, gase...

journal_title：British journal of anaesthesia

authors： Dilger JP

更新日期：2002-07-01 00:00:00

abstract：:Protein kinase C (PKC) is a key regulatory enzyme that has been implicated as a molecular target for the action of general anaesthetics. We have determined the effects of halothane on the translocation and down-regulation of conventional PKC (cPKC) by analysing the subcellular distribution of PKC activity, [3H]phorbol...

journal_title：British journal of anaesthesia

authors： Hemmings HC Jr,Adamo AI

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:The analgesia/nociception index (ANI), a 0-100 non-invasive index calculated from heart rate variability, reflects the analgesia/nociception balance during general anaesthesia. The aim of this study was to evaluate the ANI in the assessment of immediate postoperative pain in adult patients undergoing general...

journal_title：British journal of anaesthesia

authors： Boselli E,Daniela-Ionescu M,Bégou G,Bouvet L,Dabouz R,Magnin C,Allaouchiche B

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Myocardial potassium channels are complexes formed by different subunits. The subunit composition may influence the cardiotoxic action of local anaesthetics. The effects of amide local anaesthetics on HERG channels co-expressed with the putative subunit MiRP1 have not been established. It is also unclear if ...

journal_title：British journal of anaesthesia

authors： Friederich P,Solth A,Schillemeit S,Isbrandt D

更新日期：2004-01-01 00:00:00

abstract：:The use of di-isopropyl phenol (Diprivan) for induction of anaesthesia was assessed in doses ranging from 1 to 3 mg kg-1. With less than 1.75mg kg-1 not all patients were anaesthetized; 2.0 mg kg-1 appeared to be a satisfactory induction dose. Involuntary muscle movement, cough and hiccup at induction were rare with a...

journal_title：British journal of anaesthesia

authors： Briggs LP,Clarke RS,Dundee JW,Moore J,Bahar M,Wright PJ

更新日期：1981-11-01 00:00:00

abstract：:Cytokine synthesis and release is an essential component of the innate immune system, but inappropriate, excessive production results in a generalized systemic inflammatory response which damages distant organs. Recent research has identified an immunomodulatory function of the vagus nerve whereby activation of the ef...

journal_title：British journal of anaesthesia

authors： Johnston GR,Webster NR

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate whether reversal of rocuronium-induced neuromuscular blockade with sugammadex reduced the incidence of residual blockade and facilitated operating room discharge readiness. METHODS:Adult patients undergoing abdominal surgery received rocuronium, followed by randomized allocat...

journal_title：British journal of anaesthesia

authors： Brueckmann B,Sasaki N,Grobara P,Li MK,Woo T,de Bie J,Maktabi M,Lee J,Kwo J,Pino R,Sabouri AS,McGovern F,Staehr-Rye AK,Eikermann M

更新日期：2015-11-01 00:00:00

abstract：:Intrathecal midazolam causes antinociception by combining with spinal cord benzodiazepine receptors. This effect is reversible with doses of naloxone, suggesting involvement of spinal kappa or delta but not mu opioid receptors. The antinociceptive effects of intrathecally administered drugs in the spinal cord were dem...

journal_title：British journal of anaesthesia

authors： Goodchild CS,Guo Z,Musgreave A,Gent JP

更新日期：1996-12-01 00:00:00

abstract：:We have assessed a prototype laryngeal mask airway (pLMA) in 50 anaesthetized children for ease of insertion, oropharyngeal leak pressures, gastric insufflation and fibreoptic position. The pLMA has a second smaller mask, which rests against the upper oesophageal sphincter, and a second cuff to increase the seal press...

journal_title：British journal of anaesthesia

authors： Lopez-Gil M,Brimacombe J,Brain AI

更新日期：1999-01-01 00:00:00

abstract：:Arterial blood and expired gas samples were taken from 20 patients before operation and on the first day after upper abdominal surgery. After operation the patients were studied breathing air and also breathing 35% oxygen from a venturi-type mask. Preoperative Pao2 with age was exaggerated by operation. Pao2 after ope...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1975-04-01 00:00:00

abstract：:Haemodynamic effects may occur after stellate ganglion block (SGB) arising from autonomic imbalance and local anaesthetic infiltration to barosensitive areas. We report seven patients who developed severe hypertension (systolic arterial pressure >200 mm Hg) after SGB in our pain clinic service. We postulate that diffu...

journal_title：British journal of anaesthesia

authors： Kimura T,Nishiwaki K,Yokota S,Komatsu T,Shimada Y

更新日期：2005-06-01 00:00:00

abstract：:The rate of gastric emptying in pregnancy was measured indirectly using the rate of paracetamol absorption in four groups of 15 patients: non-pregnant controls, first trimester patients presenting for termination of pregnancy, second trimester patients presenting for prostaglandin termination of pregnancy, and patient...

journal_title：British journal of anaesthesia

authors： Macfie AG,Magides AD,Richmond MN,Reilly CS

更新日期：1991-07-01 00:00:00

abstract：:Chlorhexidine allergy has been described in the literature, mainly in Japanese individuals. Most reactions have been limited to the skin, mild in severity and a result of chlorhexidine containing solutions such as 'Savlon' (Novartis Consumer Health, Horesham, UK). We describe what we believe is the first reported case...

journal_title：British journal of anaesthesia

authors： Stephens R,Mythen M,Kallis P,Davies DW,Egner W,Rickards A

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Reported outcome benefits after surgical pleth index (SPI, GE Healthcare, Helsinki, Finland) guided anaesthesia are conflicting. One potential explanation may be the lack of evidence for the selection of meaningful SPI target values. A recently published trial found an SPI cut-off of 30 as a 'best-fit' to pr...

journal_title：British journal of anaesthesia

authors： Ledowski T,Schneider M,Gruenewald M,Goyal RK,Teo SR,Hruby J

更新日期：2019-08-01 00:00:00

abstract：:The safety of aspirin therapy in neuraxial anaesthesia has been historically questioned, and the current recommendations are still heterogeneous. A comprehensive review of clinical evidence and a comparative analysis of European and American guidelines were performed. Low-dose aspirin produces a selective, complete an...

journal_title：British journal of anaesthesia

authors： Vela Vásquez RS,Peláez Romero R

更新日期：2015-11-01 00:00:00

abstract：:A 38-yr-old woman with an atrial septum defect and Eisenmenger syndrome was scheduled for a lung biopsy via thoracoscopy during one-lung ventilation. Fluids were given to increase central venous pressure to 8 mm Hg, an epidural catheter was inserted at the sixth thoracic intervertebral space and ropivacaine 0.3%, 6 ml...

journal_title：British journal of anaesthesia

authors： Heller AR,Litz RJ,Koch T

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Cyclic redistribution of air within the cuff during respiratory pressure changes creates a self-sealing mechanism which allows tracheal sealing, despite tracheal airway pressure being above baseline cuff inflation pressure. The aim of the present study was to investigate the effect of continuous automated cu...

journal_title：British journal of anaesthesia

authors： Weiss M,Doell C,Koepfer N,Madjdpour C,Woitzek K,Bernet V

更新日期：2009-02-01 00:00:00

abstract：:The study was performed to determine the ED50 and ED95 of a continuous infusion of the emulsion formulation of propofol during 67% nitrous oxide anaesthesia in 57 patients premedicated with morphine sulphate 0.15 mg kg-1. Anaesthesia was induced with propofol 2 mg kg-1, and maintained before incision with a fixed-rate...

journal_title：British journal of anaesthesia

authors： Spelina KR,Coates DP,Monk CR,Prys-Roberts C,Norley I,Turtle MJ

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:In critically ill children, monitoring of cardiac output (CO) is essential to guide haemodynamic management and facilitate cardiovascular therapy. The ultrasound dilution technique (UDT), a novel minimally invasive indicator method, was recently introduced to determine CO. We validated UDT against the 'gold ...

journal_title：British journal of anaesthesia

authors： Boehne M,Baustert M,Paetzel V,Köditz H,Schoof S,Happel CM,Bertram H

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:There have been few studies comparing the response to asphyxia and the effectiveness of typical cardiopulmonary resuscitation (CPR) using exogenous epinephrine administration and manual closed-chest compression between total intravenous anaesthesia (TIVA) and inhalational anaesthesia. METHODS:Twenty pigs we...

journal_title：British journal of anaesthesia

authors： Kurita T,Morita K,Kazama T,Sato S

更新日期：2003-12-01 00:00:00