Abstract:
BACKGROUND:In regional anaesthesia, there is a risk of direct nerve injury. The purpose of this study was to determine whether the diameter of the applied needle is associated with the magnitude of nerve injury after needle nerve perforation. METHODS:In five anaesthetized pigs, the brachial plexus were exposed bilaterally. Up to eight nerves underwent needle nerve perforation using a 24 G pencil-point cannula (small diameter) or a 19 G pencil-point needle (large diameter). After 48 h, the nerves were resected during anaesthesia. The specimens were processed for visual examination and the detection of inflammatory cells, myelin damage and intraneural haematoma. The grade of nerve injury was scored ranging from 0 (no injury) to 4 (severe injury). RESULTS:Forty-eight nerves were examined. The applied injury score was significantly lower in the small-diameter group [median (inter-quartile range) 2.0 (2.0-2.0)] compared with the large-diameter group [3.5 (3.0-4.0) P<0.01]. Myelin damage and intraneural haematoma occurred predominantly in the large-diameter group. Signs of post-traumatic regional inflammation were comparable among both groups. CONCLUSIONS:The severity of nerve injury after needle nerve perforation was related to the diameter of the applied cannula. However, no such difference exists for regional inflammation. Functional consequences of these findings need to be determined. Currently, small-diameter cannulae may be advisable for peripheral nerve blocks to minimize the risk of nerve injury in the case of nerve perforation.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Steinfeldt T,Nimphius W,Werner T,Vassiliou T,Kill C,Karakas E,Wulf H,Graf Jdoi
10.1093/bja/aep366subject
Has Abstractpub_date
2010-02-01 00:00:00pages
245-53issue
2eissn
0007-0912issn
1471-6771pii
S0007-0912(17)34637-8journal_volume
104pub_type
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journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1977-11-01 00:00:00
abstract::We report the anaesthetic management of a male neonate with congenital cyst adenoid malformation (CCAM) of the lung who underwent thoracotomy for resection of CCAM 24 h after birth and again at 24 days. The initial operation involved a 10-day admission to a paediatric intensive care unit (PICU) requiring ventilation, ...
journal_title:British journal of anaesthesia
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更新日期:2005-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:Overt stroke after non-cardiac surgery has a substantial impact on the duration and quality of life. Covert stroke in the non-surgical setting is much more common than overt stroke and is associated with an increased risk of cognitive decline and dementia. Little is known about covert stroke after non-cardia...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,多中心研究
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更新日期:2016-08-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 杂志文章
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更新日期:1978-08-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-11-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 杂志文章
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更新日期:2002-04-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 杂志文章,评审
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更新日期:2002-07-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2020-02-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-06-01 00:00:00
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更新日期:2020-03-01 00:00:00
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更新日期:2014-02-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1016/j.bja.2019.07.030
更新日期:2019-12-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1990-02-01 00:00:00
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doi:10.1093/bja/86.3.388
更新日期:2001-03-01 00:00:00
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更新日期:2018-11-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1999-06-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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更新日期:2009-04-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/47.4.475
更新日期:1975-04-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2007-09-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/oxfordjournals.bja.a013453
更新日期:2000-03-01 00:00:00