Pharmacokinetics of edrophonium in anephric and renal transplant patients.

abstract：:We have studied 14 female patients undergoing elective laparoscopy under general anaesthesia with peritoneal insufflation of carbon dioxide in order to examine changes in physiological deadspace (VDphys), arterial to end-tidal carbon dioxide partial pressure difference (PaCO2-PE' CO2) and PaCO2. VCO2 increased after i...

journal_title：British journal of anaesthesia

authors： Puri GD,Singh H

更新日期：1992-02-01 00:00:00

abstract：:Arterial oxygenation was measured in patients being ventilated artificially for respiratory failure, initially at the FIO2 that had been selected clinically to achieve PaO2 at least normal, and then at each of two or three progressively increased FIO2 values up to about 0.9. Impairment of oxygen transfer was assessed ...

journal_title：British journal of anaesthesia

authors： Drummond GB,Zhong NS

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Miller laryngoscope blades are preferred for laryngoscopy in infants and children <2 yr of age. Despite their long history, the laryngeal view with the Miller blade size 1 has never been compared with that with the Macintosh (MAC) blade in children. This prospective, single-blinded, randomized study was desi...

journal_title：British journal of anaesthesia

authors： Passi Y,Sathyamoorthy M,Lerman J,Heard C,Marino M

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The effect of anaesthesia on postoperative outcome is unclear. Cardioprotective properties of volatile anaesthetics have been demonstrated experimentally and in haemodynamically stable patients undergoing coronary artery bypass grafting. Their effects in patients undergoing high-risk cardiac surgery have not...

journal_title：British journal of anaesthesia

authors： Landoni G,Guarracino F,Cariello C,Franco A,Baldassarri R,Borghi G,Covello RD,Gerli C,Crivellari M,Zangrillo A

更新日期：2014-12-01 00:00:00

abstract：:It is known that propofol can have effects on atrioventricular node conduction. We report a case where administration of propofol was associated with termination of supraventricular tachycardia. Although a similar phenomenon has been reported in children, this is the first such case in an adult. ...

journal_title：British journal of anaesthesia

authors： Kannan S,Sherwood N

更新日期：2002-06-01 00:00:00

abstract：:Bispectral index (BIS) was assessed as a monitor of depth of anaesthesia during fentanyl and midazolam anaesthesia for coronary bypass surgery. In 10 patients given morphine premedication, anaesthesia was induced with a combination of midazolam and fentanyl and thereafter maintained with a continuous infusion of a mix...

journal_title：British journal of anaesthesia

authors： Barr G,Anderson RE,Samuelsson S,Owall A,Jakobsson JG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Single preoperative gabapentinoid (gabapentin and pregabalin) administration has been associated with respiratory depression during Phase I anaesthesia recovery. In this study, we assess for associations between chronic (home) use and perioperative administration (preoperative and postoperative) of gabapenti...

journal_title：British journal of anaesthesia

authors： Deljou A,Hedrick SJ,Portner ER,Schroeder DR,Hooten WM,Sprung J,Weingarten TN

更新日期：2018-04-01 00:00:00

abstract：:In a controlled, randomized study, we evaluated duration of neuromuscular block in 80 patients undergoing routine abdominal surgery. Forty patients were aged 18-50 yr (control group) and 40 patients were more than 65 yr (elderly group). All patients had normal plasma creatinine concentrations. After induction of anaes...

journal_title：British journal of anaesthesia

authors： Slavov V,Khalil M,Merle JC,Agostini MM,Ruggier R,Duvaldestin P

更新日期：1995-06-01 00:00:00

abstract：:We have investigated the effect of a bolus injection of atracurium 0.6 mg kg-1 on the cardiovascular system in 16 patients undergoing aortocoronary bypass surgery. H1- and H2-receptor antagonists were administered to eight patients before the neuromuscular blocker. A standard anaesthetic was used comprising fentanyl, ...

journal_title：British journal of anaesthesia

authors： Adt M,Baumert JH,Reimann HJ

更新日期：1992-02-01 00:00:00

abstract：:A simple method of adapting a pressure-cycled ventilator of the flow generator type to ventilate patients on a circle-absorber anaesthetic system is described. Standard lengths of corrugated black rubber tubing are placed between the ventilator and the circle-absorber is deadspace, replacing the reservoir bag. The per...

journal_title：British journal of anaesthesia

authors： Jeal DE

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:The low and moderate doses of dexmedetomidine reduce arterial pressure and heart rate (HR), suggesting attenuation of sympathetic activity and dominance of cardiac-vagal activity. These autonomic responses under dexmedetomidine sedation may attenuate cardiovascular reflex responses to temporal reduction in a...

journal_title：British journal of anaesthesia

authors： Kato J,Ogawa Y,Kojima W,Aoki K,Ogawa S,Iwasaki K

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Anaesthesia and surgery are associated with impairment of the immune system expressed as an excessive proinflammatory immune response and suppression of cell-mediated immunity that may affect the course of the postoperative period. Addition of anaesthetic agents capable of attenuating the alterations in peri...

journal_title：British journal of anaesthesia

authors： Beilin B,Rusabrov Y,Shapira Y,Roytblat L,Greemberg L,Yardeni IZ,Bessler H

更新日期：2007-10-01 00:00:00

abstract：:We have compared the ability of naïve intubators to intubate the trachea using a laryngoscope and an intubating laryngeal mask airway (ILMA) after receiving basic training, in a randomized, prospective, crossover study in 60 patients. Ventilation of the lungs via the ILMA was also compared with ventilation with a face...

journal_title：British journal of anaesthesia

authors： Avidan MS,Harvey A,Chitkara N,Ponte J

更新日期：1999-10-01 00:00:00

abstract：:Methylene blue-treated fresh-frozen plasma (MB-FFP) is mainly used in Europe. The advantage of the methylene blue system is that units can be treated individually. The combined action of methylene blue and illumination is a photodynamic process preventing viral RNA and DNA replication. We report the first immediate al...

journal_title：British journal of anaesthesia

authors： Dewachter P,Castro S,Nicaise-Roland P,Chollet-Martin S,Le Beller C,Lillo-le-Louet A,Mouton-Faivre C

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The revised cardiac risk index (RCRI) is associated strongly with increased cardiac ischaemic risk and perioperative death. Associations with non-cardiac morbidity in non-cardiac surgery have not been explored. In the elective orthopaedic surgical population, morbidity is common but preoperative predictors a...

journal_title：British journal of anaesthesia

authors： Ackland GL,Harris S,Ziabari Y,Grocott M,Mythen M,SOuRCe Investigators.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:One major risk factor of the sitting position for neurosurgery is air embolism, especially in patients with persistent foramen ovale (PFO). The first aim of this prospective study was to evaluate a bedside method for detecting PFO using transcranial Doppler sonography (TCD) with contrast medium. A second aim...

journal_title：British journal of anaesthesia

authors： Engelhardt M,Folkers W,Brenke C,Scholz M,Harders A,Fidorra H,Schmieder K

更新日期：2006-04-01 00:00:00

abstract：:We have compared, in a double-blind study, the efficacy of flumazenil with that of aminophylline in antagonizing the effects of midazolam in 60 patients (ASA I-II, mean age 66 yr) undergoing transurethral resection of prostate under spinal anaesthesia. All patients received midazolam 0.075 mg kg-1 i.v. and the test dr...

journal_title：British journal of anaesthesia

authors： Sibai AN,Sibai AM,Baraka A

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Ketamine is used as an anaesthetic agent for short surgical procedures, and as a sedative and analgesic in intensive care patients. Intensive care patients with brain or spinal cord injury may have physiological changes that could alter the pharmacokinetics of ketamine. The pharmacokinetics of ketamine have ...

journal_title：British journal of anaesthesia

authors： Hijazi Y,Bodonian C,Bolon M,Salord F,Boulieu R

更新日期：2003-02-01 00:00:00

abstract：:Fires and explosions have occurred in the operating theatre for many years. Flammable inhalation anaesthetic agents were responsible for many incidents in the past, but these are no longer available in many countries. Other causes of fires and explosions still exist in the operating theatre and, from time to time, res...

journal_title：British journal of anaesthesia

authors： Macdonald AG

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is an α-2-receptor agonist which might be used as an additive to local anaesthetics for various regional anaesthetic techniques. We therefore designed this prospective, double-blinded, controlled volunteer study to investigate the effects of dexmedetomidine as an adjuvant to ropivacaine on pe...

journal_title：British journal of anaesthesia

authors： Marhofer D,Kettner SC,Marhofer P,Pils S,Weber M,Zeitlinger M

更新日期：2013-03-01 00:00:00

abstract：:We have investigated 296 inpatients in a single-blind observer study to determine the incidence, degree and duration of hypoxaemia during anaesthesia. The clinical recognition of hypoxaemia, period of time until recognition and risk factors were studied. Oxygen saturation (Spo2) was monitored continuously with a pulse...

journal_title：British journal of anaesthesia

authors： Moller JT,Johannessen NW,Berg H,Espersen K,Larsen LE

更新日期：1991-04-01 00:00:00

abstract：:Plasma concentrations of pancuronium were measured in nine patients undergoing surgery because of total biliary obstruction. When compared with the averaged model-independent pharmacokinetic parameters obtained for normal patients, the terminal half-life of 270 min was more than twice normal (132 min, P less than 0.00...

journal_title：British journal of anaesthesia

authors： Somogyi AA,Shanks CA,Triggs EJ

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Microvascular dysfunction is considered to play an important pathophysiological role in sepsis. We addressed the hypothesis that macrovascular and microvascular flow are uncoupled in early sepsis, using a rodent model with well-characterized haemodynamic and biochemical markers of severity and subsequent mor...

journal_title：British journal of anaesthesia

authors： Dyson A,Cone S,Singer M,Ackland GL

更新日期：2012-06-01 00:00:00

abstract：:Zomepirac 100 mg and dihydrocodeine 30 mg were compared with placebo in a controlled randomized, double-blind, single-dose postoperative study. Patients continued to receive either zomepirac or dihydrocodeine for pain relief for 5 days at home in a double-blind study, being allowed to titrate the consumption of tablet...

journal_title：British journal of anaesthesia

authors： McQuay HJ,Bullingham RE,Moore RA,Carroll D,Evans PJ,O'Sullivan G,Collin J,Lloyd JW

更新日期：1985-04-01 00:00:00

abstract：:We have studied the effects of alfentanil administered intrathecally on somatosympathetic reflexes evoked by stimulation of radial and tibial nerves in 10 anaesthetized and paralysed dogs. In five animals, alfentanil was administered in doses of 100, 100, 200 and 400 micrograms in 0.8 ml and 800 micrograms in 1.6 ml p...

journal_title：British journal of anaesthesia

authors： Wang C,Chakrabarti MK,Whitwam JG

更新日期：1992-05-01 00:00:00

abstract：:We have investigated the effect of volatile anaesthetics on protein synthesis and secretion in Hartley male guinea pig liver slices. The slices (250-300 microns thick) were incubated in sealed roller vials containing Krebs-Henseleit buffer at 37 degrees C under 95% oxygen. Volatile anaesthetics were vaporized in the v...

journal_title：British journal of anaesthesia

authors： Ghantous HN,Fernando JL,Keith RL,Gandolfi AJ,Brendel K

更新日期：1992-02-01 00:00:00

abstract：:We report a case of massive pulmonary embolism occurring at the time of graft reperfusion in a patient undergoing orthotopic liver transplantation. The clinical diagnosis of pulmonary embolus was aided by on-table echocardiography. Cardiopulmonary bypass and surgical embolectomy prevented her death. We discuss the dif...

journal_title：British journal of anaesthesia

authors： Manji M,Isaac JL,Bion J

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Recent investigations showed that isoflurane can induce pharmacological preconditioning. The present study aimed to compare the potency of four different halogenated anaesthetics to induce preconditioning. METHODS:Anaesthetized open-chest rabbits underwent 30 min of coronary artery occlusion followed by 3 h...

journal_title：British journal of anaesthesia

authors： Piriou V,Chiari P,Lhuillier F,Bastien O,Loufoua J,Raisky O,David JS,Ovize M,Lehot JJ

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:An important cause of coagulopathy in cardiac surgery is impaired thrombin generation. While plasma is often used to correct this element of the coagulopathy, studies in vitro suggest that prothrombin complex concentrates (PCCs) might be more effective. Comparative data, however, are scant. METHODS:We compa...

journal_title：British journal of anaesthesia

authors： Fitzgerald J,Lenihan M,Callum J,McCluskey SA,Srinivas C,van Rensburg A,Karkouti K

更新日期：2018-05-01 00:00:00

abstract：:We have compared iontophoretically and locally applied lidocaine for relief of pain on propofol injection. Pain was assessed on insertion of a 20-gauge i.v. cannula and at 10-s intervals for 30 s after injection of propofol. Pain scores on cannulation were significantly less in the iontophoresis group (median 1.1) tha...

journal_title：British journal of anaesthesia

authors： Sadler PJ,Thompson HM,Maslowski P,Liddle A,Rowbotham DJ

更新日期：1999-03-01 00:00:00