Anaphylactic reaction after methylene blue-treated plasma transfusion.

Abstract:

:Methylene blue-treated fresh-frozen plasma (MB-FFP) is mainly used in Europe. The advantage of the methylene blue system is that units can be treated individually. The combined action of methylene blue and illumination is a photodynamic process preventing viral RNA and DNA replication. We report the first immediate allergic hypersensitivity reaction to methylene blue-treated plasma transfusion. The clinical course and subsequent assessment of the allergic reaction, including skin tests and basophil activation test, confirmed methylene blue-induced IgE-mediated anaphylaxis. All immediate reactions after MB-FFP transfusion should be investigated to document the underlying mechanism.

journal_name

Br J Anaesth

authors

Dewachter P,Castro S,Nicaise-Roland P,Chollet-Martin S,Le Beller C,Lillo-le-Louet A,Mouton-Faivre C

doi

10.1093/bja/aer009

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

687-9

issue

5

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)33217-8

journal_volume

106

pub_type

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