Anaphylactic reaction after methylene blue-treated plasma transfusion.


:Methylene blue-treated fresh-frozen plasma (MB-FFP) is mainly used in Europe. The advantage of the methylene blue system is that units can be treated individually. The combined action of methylene blue and illumination is a photodynamic process preventing viral RNA and DNA replication. We report the first immediate allergic hypersensitivity reaction to methylene blue-treated plasma transfusion. The clinical course and subsequent assessment of the allergic reaction, including skin tests and basophil activation test, confirmed methylene blue-induced IgE-mediated anaphylaxis. All immediate reactions after MB-FFP transfusion should be investigated to document the underlying mechanism.


Br J Anaesth


Dewachter P,Castro S,Nicaise-Roland P,Chollet-Martin S,Le Beller C,Lillo-le-Louet A,Mouton-Faivre C




Has Abstract


2011-05-01 00:00:00














  • Effect of baricity on spinal anaesthesia with amethocaine.

    abstract::Amethocaine 1% solution was mixed with equal volumes of water, 0.9% saline or 10% dextrose to prepare respectively, hypobaric, isobaric and hyperbaric solutions which were compared for intradural spinal anaesthesia in 60 patients. Thirty patients received 10 mg and 30 patients received 15 mg of amethocaine. Injections...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Brown DT,Wildsmith JA,Covino BG,Scott DB

    更新日期:1980-06-01 00:00:00

  • Continuous infusions of propofol administered to dogs: effects on ICG and propofol disposition.

    abstract::We have studied the effects of stepwise increasing infusion rates of propofol 200-500 micrograms kg-1 min-1 on blood concentrations of propofol and the disposition and clearance of a bolus dose of indocyanine green (ICG) 0.5 mg kg-1 in 10 acutely instrumented dogs. Drug concentrations and ICG clearance were measured 3...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Sear JW,Diedericks J,Foex P

    更新日期:1994-04-01 00:00:00

  • Peripheral nerve injury caused by injection needles used in regional anaesthesia: influence of bevel configuration, studied in a rat model.

    abstract::We have studied the immediate and long term (up to 28 days) effects of short and long bevelled needle impalement of the rat sciatic nerve. Three techniques were used to assess neural trauma and its consequences: stained longitudinal nerve sections were assessed by light microscopy and scored for injury; the extravasat...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Rice AS,McMahon SB

    更新日期:1992-11-01 00:00:00

  • Ergometrine or oxytocin? Blood loss and side-effects at spontaneous vertex delivery.

    abstract::Blood loss and the frequency of vomiting were assessed at 88 spontaneous vertex deliveries. An i.v. injection of oxytocin 10 u was as effective as ergometrine 0.5 mg in controlling bleeding from the uterus after delivery. The continuous infusion of a dilute solution of oxytocin in the first stage of labour was not fol...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Moir DD,Amoa AB

    更新日期:1979-02-01 00:00:00

  • Comparison of morphine alone with morphine plus clonidine for postoperative patient-controlled analgesia.

    abstract:BACKGROUND:Clonidine is an alpha 2 adrenergic agonist with analgesic properties. This study aimed to see if the addition of clonidine to morphine when given by patient-controlled analgesia (PCA) would improve analgesia beyond the first 12 h after surgery. METHODS:Sixty patients undergoing lower abdominal surgery were ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Jeffs SA,Hall JE,Morris S

    更新日期:2002-09-01 00:00:00

  • Performance assessment of a fuzzy controller for atracurium-induced neuromuscular block.

    abstract::The performance of a fuzzy controller for atracurium-induced neuromuscular block was assessed. Ten ASA I or II patients undergoing surgery anticipated to last at least 120 min were studied. A Datex Relaxograph was used to monitor neuromuscular block. Initially the T1 set point was set at 10% of baseline for at least 3...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Mason DG,Edwards ND,Linkens DA,Reilly CS

    更新日期:1996-03-01 00:00:00

  • Predicting postoperative nausea and vomiting with the application of an artificial neural network.

    abstract:BACKGROUND:Several medications have proved to be useful in preventing postoperative nausea and vomiting (PONV). However, routine antiemetic prophylaxis is not cost-effective. We evaluated the accuracy and discriminating power of an artificial neural network (ANN) to predict PONV. METHODS:We analysed data from 1086 in-...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Peng SY,Wu KC,Wang JJ,Chuang JH,Peng SK,Lai YH

    更新日期:2007-01-01 00:00:00

  • Pharmacokinetics of pancuronium in patients with normal and impaired renal function.

    abstract::Plasma concentrations of pancuronium were measured using a fluorimetric method in six patients with normal renal function and seven patients in chronic renal failure. A tow-compartment open model was used in the pharmacokinetic analysis of the data. With this model, the clearance of pancuronium was found to be reduce...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: McLeod K,Watson MJ,Rawlins MD

    更新日期:1976-04-01 00:00:00

  • Comparative haemodynamic effects of tubocurarine and metocurine in the dog.

    abstract::On accout of its histamine releasing and ganglion blocking properties tubocurarine is known to have significant haemodynamic effects. Methylation of the compound produces metocurine and should decrease both histamine release and ganglionic blockade. The haemodynamic effects of these two compounds were compared in 10 m...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Antonio RP,Philbin DM,Savarese JJ

    更新日期:1979-11-01 00:00:00

  • Impact of metabolic syndrome in surgical patients: should we bother?

    abstract::Clinicians inevitably encounter patients who meet the diagnostic criteria for the metabolic syndrome (MetS); these criteria include central obesity, hypertension, atherogenic dyslipidaemia, and hyperglycaemia. Regardless of the variations in its definition, MetS may be associated with adverse outcomes in patients unde...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审


    authors: Tzimas P,Petrou A,Laou E,Milionis H,Mikhailidis DP,Papadopoulos G

    更新日期:2015-08-01 00:00:00

  • Remifentanil in combination with propofol for spontaneous ventilation anaesthesia.

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    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


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  • Randomized, prospective, observational simulation study comparing residents' needle-guided vs free-hand ultrasound techniques for central venous catheter access.

    abstract:BACKGROUND:Short-axis ultrasound-guided placement of central venous catheters (CVCs) is widely accepted as safe practice. However, utilizing the long-axis approach could further improve safety, as it allows for better visualization of the needle as it is advanced to the target vessel. However, the long-axis approach ha...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验


    authors: Ball RD,Scouras NE,Orebaugh S,Wilde J,Sakai T

    更新日期:2012-01-01 00:00:00

  • Rhabdomyolysis in an obese patient after total knee arthroplasty.

    abstract::We report the case of a morbidly obese patient who developed rhabdomyolysis with acute renal failure, hepatic dysfunction, and an increase of cardiac troponin-1 after total knee arthroplasty. Postoperative rhabdomyolysis has a wide range of triggers and differential diagnoses that should be considered by the anaesthes...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Karcher C,Dieterich HJ,Schroeder TH

    更新日期:2006-12-01 00:00:00

  • The intubating laryngeal mask airway: an initial assessment of performance.

    abstract::A new prototype of the laryngeal mask airway (LMA), the intubating laryngeal mask airway (ILMA), was used to facilitate tracheal intubation in 100 fasted patients presenting for elective surgery. Alignment of the ILMA with the larynx was assessed fibreoptically before intubation without the investigator performing the...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章


    authors: Kapila A,Addy EV,Verghese C,Brain AI

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  • Beneficial effects of statins on the microcirculation during sepsis: the role of nitric oxide.

    abstract::This review describes the laboratory evidence and microvascular mechanisms responsible for the beneficial effects of statins in sepsis. During sepsis, changes occur within the microcirculation including alterations in arteriolar tone influencing blood pressure, adaptations to endothelial cell integrity causing leakage...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审


    authors: McGown CC,Brookes ZL

    更新日期:2007-02-01 00:00:00

  • Effects of subanaesthetic sevoflurane on ventilation. 1: Response to acute and sustained hypercapnia in humans.

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    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章


    authors: Pandit JJ,Manning-Fox J,Dorrington KL,Robbins PA

    更新日期:1999-08-01 00:00:00

  • Effect of segmental extradural analgesia on placental blood flow during normal labour.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Jouppila R,Jouppila P,Hollmén A,Kuikka J

    更新日期:1978-06-01 00:00:00

  • Dose-response relationships for neostigmine antagonism of rocuronium-induced neuromuscular block in children and adults.

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    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Abdulatif M,Mowafi H,al-Ghamdi A,el-Sanabary M

    更新日期:1996-12-01 00:00:00

  • Comparison of Alaris AEP index and bispectral index during propofol-remifentanil anaesthesia.

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    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Kreuer S,Bruhn J,Larsen R,Hoepstein M,Wilhelm W

    更新日期:2003-09-01 00:00:00

  • Enteral absorption and haemodynamic response of clonidine in infants post-cardiac surgery.

    abstract:BACKGROUND:Clonidine is a useful analgesic-sedative agent; however, few data exist regarding its use in infants after congenital heart disease surgery. We thus aimed to assess the absorption and safety of enterally administered clonidine in this setting. METHODS:Sixteen infants (median age 6.7 months) received a singl...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Arenas-Lopez S,Mulla H,Manna S,Durward A,Murdoch IA,Tibby SM

    更新日期:2014-12-01 00:00:00

  • Hand-hygiene practices in the operating theatre: an observational study.

    abstract:BACKGROUND:The current prevalence of healthcare-associated infections (HCAIs) is a major public health concern. Patient contact in the operating theatre (OT) can contribute to HCAI via microbial contamination. The application of hand hygiene is effective in reducing infection rates. Limited data are available on adhere...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Krediet AC,Kalkman CJ,Bonten MJ,Gigengack AC,Barach P

    更新日期:2011-10-01 00:00:00

  • Aspirin and spinal haematoma after neuraxial anaesthesia: Myth or reality?

    abstract::The safety of aspirin therapy in neuraxial anaesthesia has been historically questioned, and the current recommendations are still heterogeneous. A comprehensive review of clinical evidence and a comparative analysis of European and American guidelines were performed. Low-dose aspirin produces a selective, complete an...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审


    authors: Vela Vásquez RS,Peláez Romero R

    更新日期:2015-11-01 00:00:00

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    abstract:BACKGROUND:Target-controlled infusion (TCI) systems use pharmacokinetic (PK) models to predict the drug infusion rates necessary to achieve a desired target plasma or effect-site concentration. As new PK models are developed and implemented in TCI systems, there can be uncertainty as to which target concentrations are ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Eleveld DJ,Colin P,Absalom AR,Struys MMRF

    更新日期:2020-10-01 00:00:00

  • Postoperative analgesia with Duromorph.

    abstract::The analgesic effects and bioavailability of a slow-release preparation of morphine (Duromorph) were studied in 12 patients with acute postoperative pain. Duromorph produced significant analgesia within 1-2 h of administration i.m., and there was a progressive decrease in the mean pain score for at least 8 h. None of ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Charway CL,Calvey TN,Williams NE,Murray GR

    更新日期:1985-10-01 00:00:00

  • Postpartum cerebral ischaemia after accidental dural puncture and epidural blood patch.

    abstract::Puerperal women are reported to have a rate of cerebral infarction 13 times greater than non-pregnant females. We report a case of cerebral ischaemia in a 30-yr-old healthy parturient after epidural analgesia for labour, complicated by dural puncture treated with two epidural blood patches. Investigations showed the d...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Mercieri M,Mercieri A,Paolini S,Arcioni R,Lupoi D,Passarelli F,Pinto G,Celleno D

    更新日期:2003-01-01 00:00:00

  • Studies of drugs given before anaesthesia. XXII: Metoclopramide.

    abstract::Metoclopramide hastens emptying of the stomach. Since it may be given to patients before operation, the sedative and toxic effects of 10- and 20-mg does given i.m. were studied in patients and student volunteers. Saline and diazepam 10 mg were used as placebo and reference drugs. Neither dose of metoclopramide had as ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章


    authors: Dundee JW,Clarke RS,Howard PJ

    更新日期:1974-07-01 00:00:00

  • Effect of diluting propofol on the incidence of pain on injection and venous sequelae.

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    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Stokes DN,Robson N,Hutton P

    更新日期:1989-02-01 00:00:00

  • Effect of atropine on the QT interval and T-wave amplitude in healthy volunteers.

    abstract::Prolongation of the QT interval of the ECG represents an imbalance in cardiac autonomic function and may predict cardiac arrhythmia. Vagal activity protects against prolongation of the QT interval which may be associated with flattening of the T-wave of the ECG. The changes in QT interval, T-wave amplitude and respira...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Annila P,Yli-Hankala A,Lindgren L

    更新日期:1993-11-01 00:00:00

  • Pathology in the extradural space.

    abstract::The case histories are reported of one patient who developed evidence of extradural infection 16 days postpartum, and another who spontaneously developed an extradural haematoma. Several points of interest and concern raised by these case histories are discussed. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章


    authors: Crawford JS

    更新日期:1975-03-01 00:00:00

  • Perioperative management of patients with suspected or confirmed COVID-19: review and recommendations for perioperative management from a retrospective cohort study.

    abstract:BACKGROUND:Current guidelines for perioperative management of coronavirus disease 19 (COVID-19) are mainly based on extrapolated evidence or expert opinion. We aimed to systematically investigate how COVID-19 affects perioperative management and clinical outcomes, to develop evidence-based guidelines. METHODS:First, w...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审


    authors: Zheng H,Hébert HL,Chatziperi A,Meng W,Smith BH,Yan J,Zhou Z,Zhang X,Luo A,Wang L,Zhu W,Hu J,Colvin LA

    更新日期:2020-12-01 00:00:00